阅读说明：本技术 杀真菌组合物 (Fungicidal compositions ) 是由 L·夸兰塔 F·博哈姆丹 M·魏斯 于 2019-09-24 设计创作，主要内容包括：披露了一种杀真菌组合物,其包含组分(A)和组分(B)的混合物,其中组分(A)是具有式I的8-氟喹啉-3-甲酰胺并且组分(B)选自由以下组成的组：氟唑菌酰羟胺、苯并烯氟菌唑、苯醚甲环唑、己唑醇、嘧菌酯、咯菌腈、嘧菌环胺、氟啶胺、吡唑萘菌胺、咯喹酮、三环唑、百菌清、丙环唑、氨基吡分、戊菌唑、丙硫菌唑、代森锰锌、丁苯吗啉、苯锈啶、硫以及枯草芽孢杆菌菌株,以及所述组合物在农业或园艺学中用于控制或预防植物病原性微生物、优选真菌侵染植物的用途。(Disclosed is a fungicidal composition comprising a mixture of component (A) and component (B), wherein component (A) is an 8-fluoroquinoline-3-carboxamide having formula I and component (B) is selected from the group consisting of: fluxapyroxad, benzovindiflupyr, difenoconazole, hexaconazole, azoxystrobin, fludioxonil, cyprodinil, fluazinam, isopyrazam, pyroquilon, tricyclazole, chlorothalonil, propiconazole, aminopyridine, penconazole, prothioconazole, mancozeb, fenpropimorph, fenpropidin, sulphur and bacillus subtilis strains, and the use of said compositions in agriculture or horticulture for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi.)

1. a fungicidal composition comprising a mixture of component (A) and component (B), wherein component (A) is a compound having the formula (I)

Wherein

R₁Is hydrogen or methyl;

R₂is hydrogen or methyl;

R₃is hydrogen or methyl;

R₄is-C (Cl) ═ CH₂Isopropyl, 1-methylcyclopropyl, trifluoromethyl, -C (CH)₃)＝CH₂Or a tert-butyl group;

or a salt, enantiomer and/or N-oxide thereof;

and is

Component (B) is a compound selected from the group consisting of:

fluxapyroxad,

Benzovindiflupyr,

Difenoconazole,

Hexaconazole,

Azoxystrobin,

Fludioxonil, fludioxonil,

Cyprodinil,

Fluazinam,

Isopyrazam,

A praziquantel,

Tricyclazole,

Chlorothalonil,

Propiconazole,

Amino pyridine,

Penconazole,

Prothioconazole,

Mancozeb,

Fenpropimorph,

Fenpropidin,

Sulfur, and

biological fungicides containing strains of Bacillus subtilis, e.g.(A biological fungicide comprising Bacillus amyloliquefaciens variant strain FZB24, available from Novitin Biotech, Inc. of 24153 Sehlem 5400, Virginia, USA),(based on strain QST713) or(based on strain MBI 600);

wherein the weight ratio of component (A) to component (B) is from 20:1 to 1: 40.

2. The fungicidal composition according to claim 1, wherein component (a) is a compound selected from the group consisting of:

2-benzyl-N- (8-fluoro-2-methyl-3-quinolyl) -2-methyl-3- (1-methylcyclopropyl) propanamide (E-99),

2-benzyl-N- (8-fluoro-4-methyl-3-quinolyl) -2-methyl-3- (1-methylcyclopropyl) propanamide (E-100),

2-benzyl-N- (8-fluoro-2-methyl-3-quinolyl) -3- (1-methylcyclopropyl) propanamide (E-89),

2-benzyl-N- (8-fluoro-4-methyl-3-quinolyl) -3- (1-methylcyclopropyl) propanamide (E-90),

2-benzyl-N- (8-fluoro-3-quinolyl) -3- (1-methylcyclopropyl) propanamide (E-91),

2-benzyl-N- (8-fluoro-3-quinolyl) -2-methyl-3- (1-methylcyclopropyl) propanamide (E-70),

2-benzyl-N- (8-fluoro-4-methyl-3-quinolinyl) -2, 4-dimethyl-pent-4-enamide (E-65),

2-benzyl-N- (8-fluoro-2-methyl-3-quinolinyl) -2, 4-dimethyl-pent-4-enamide (E-66),

2-benzyl-N- (8-fluoro-3-quinolinyl) -2, 4-dimethyl-pent-4-enamide (E-74),

2-benzyl-4-chloro-N- (8-fluoro-4-methyl-3-quinolinyl) -2-methyl-pent-4-enamide (E-20),

2-benzyl-4-chloro-N- (8-fluoro-2-methyl-3-quinolinyl) -2-methyl-pent-4-enamide (E-21),

2-benzyl-4-chloro-N- (8-fluoro-3-quinolinyl) -2-methyl-pent-4-enamide (E-53),

2-benzyl-4, 4, 4-trifluoro-N- (8-fluoro-2-methyl-3-quinolinyl) -2-methyl-butyramide (E-47),

2-benzyl-4, 4, 4-trifluoro-N- (8-fluoro-4-methyl-3-quinolinyl) -2-methyl-butyramide (E-50),

2-benzyl-4, 4, 4-trifluoro-N- (8-fluoro-3-quinolinyl) -2-methyl-butyramide (E-80),

2-benzyl-N- (8-fluoro-4-methyl-3-quinolinyl) -2, 4-dimethyl-pentanamide (E-84),

2-benzyl-N- (8-fluoro-2-methyl-3-quinolinyl) -2, 4-dimethyl-pentanamide (E-86),

2-benzyl-N- (8-fluoro-3-quinolinyl) -2, 4-dimethyl-pentanamide (E-87),

2-benzyl-N- (8-fluoro-4-methyl-3-quinolinyl) -4, 4-dimethyl-pentanamide (E-96),

2-benzyl-N- (8-fluoro-2-methyl-3-quinolinyl) -4, 4-dimethyl-pentanamide (E-97) and

2-benzyl-N- (8-fluoro-3-quinolyl) -4, 4-dimethyl-pentanamide (E-98),

Or a salt, enantiomer or N-oxide thereof.

3. The fungicidal composition according to claim 1 or claim 2, wherein component (a) is 2-benzyl-N- (8-fluoro-2-methyl-3-quinolinyl) -2, 4-dimethyl-pentanamide (E-86); or a salt, enantiomer or N-oxide thereof.

4. The fungicidal composition according to claim 1 or claim 2, wherein component (a) is

2-benzyl-4, 4, 4-trifluoro-N- (8-fluoro-2-methyl-3-quinolinyl) -2-methyl-butyramide (E-47); or a salt, enantiomer or N-oxide thereof.

5. The fungicidal composition according to claim 1 or claim 2, wherein component (a) is 2-benzyl-4, 4, 4-trifluoro-N- (8-fluoro-4-methyl-3-quinolinyl) -2-methyl-butyramide (E-50); or a salt, enantiomer or N-oxide thereof.

6. The fungicidal composition according to claim 1 or claim 2, wherein component (a) is 2-benzyl-N- (8-fluoro-4-methyl-3-quinolinyl) -2, 4-dimethyl-pentanamide (E-84); or a salt, enantiomer or N-oxide thereof.

7. A fungicidal composition according to any preceding claim, wherein component (a) is present as its (S) -enantiomer, or a salt or N-oxide.

8. A fungicidal composition according to any preceding claim, wherein component (a) is present as its (R) -enantiomer, or a salt or N-oxide.

9. The fungicidal composition according to any preceding claim, wherein component (B) is a compound selected from the group consisting of: fluxapyroxad, benzovindiflupyr [1072957-71-1]Difenoconazole, hexaconazole, prothioconazole, mancozeb, azoxystrobin, fludioxonil, cyprodinil, fluazinam, isopyrazam, propiconazole, aminopyridine, pyroquilon, tricyclazole, chlorothalonil, penconazole, fenpropimorph, fenpropidin, sulphur, and biological fungicides containing strains of bacillus subtilis, such as(A biological fungicide comprising Bacillus amyloliquefaciens variant strain FZB24, available from Novitin Biotech, Inc. of 24153 Sellerm 5400, Virginia, USA).

10. The fungicidal composition according to any preceding claim, wherein component (B) is a compound selected from the group consisting of: fluxapyroxad, benzovindiflupyr [1072957-71-1], difenoconazole, hexaconazole, prothioconazole, mancozeb, azoxystrobin, fludioxonil, cyprodinil, fluazinam, isopyrazam, propiconazole, aminopyridine, pyroquilon, tricyclazole and chlorothalonil.

11. The fungicidal composition according to any preceding claim, wherein the composition comprises one or more additional pesticides selected from the group consisting of:

fungicides selected from the group consisting of hymexazol, fluazinam, benalaxyl-M or kiralaxyl-M, furalaxyl, metalaxyl-M or mefenoxam, doxine, N ' - (2, 5-dimethyl-4-phenoxy-phenyl) -N-ethyl-N-methyl-formamidine, N ' - [4- (4, 5-dichloro-thiazol-2-yloxy) -2, 5-dimethyl-phenyl ] -N-ethyl-N-methyl-formamidine, N ' - [4- [ [3- [ (4-chlorophenyl) methyl ] -1,2, 4-thiadiazol-5-yl ] oxy ] -2, 5-dimethyl-phenyl ] -N-ethyl-N-methyl-formamidine, ethirimide, 3' -chloro-2-methoxy-N- [ (3RS) -tetrahydro-2-oxofuran-3-yl ] acetyl-2 ',6' -dimethylaniline (imazamide), cyprodinil, mepanipyrim, pyrimethanil, dithianon, aureomycin, blasticidin-S, biphenyl, dicyclopentadine, chloronitramine, hexachlorobenzene, quintozene, Tetraoxynitrobenzene (TCNB), tolclofos-methyl, aminopyridine, metrafenone, 2, 6-dichloro-N- (4-trifluoromethylbenzyl) -benzamide, fluopyram (fluopiolide or flucolide), thiocyanobenzamide, flusulfamide, benomyl, carbendazim hydrochloride, chlorophenol, cornin, thiabendazole, thiophanate-methyl, benthiavalicarb-isopropyl, fluazid, trifluralin, thifluazid, thifluazi, Triticonazole, thiabendazole, acibenzolar, monocalcin, pioglitazone (IKF-309), acibenzolar-S-methyl, pyribencarb (KIF-7767), butylamine, 3-iodo-2-propynyl N-butylcarbamate (IPBC), iodocarb (iodocarb) (isopropyl butylcarbamate), isopropyl butylcarbamate (iodocarb), penconazole, polycarbamate, propamocarb, toprocarb, 3- (difluoromethyl) -N- (7-fluoro-1, 1,3, 3-tetramethyl-indan-4-yl) -1-methyl-pyrazole-4-carboxamide, diclorocarbam, N- [ (5-chloro-2-isopropyl-phenyl) methyl ] -N-cyclopropyl-3- (difluoromethyl) -5-fluoro-methyl) -5-fluoro-pyrad -1-methyl-pyrazole-4-carboxamide, N-cyclopropyl-3- (difluoromethyl) -5-fluoro-N- [ (2-isopropylphenyl) methyl ] -1-methyl-pyrazole-4-carboxamide, cyprodinil, chlorothalonil, flumorph, oxine-copper, cymoxanil, cyazoxystrobin, cyazofamid, fluthiacet-ethyl, thiabendazole, iprodione, procymidone, pyrithiofamide sulfonate, clofenprophenicol, fenvalerate, chlorfenapyr, alexan, fenpyrad, diphenylamine, chlorophosphine, 2, 6-dimethyl- [1,4] dichloroanthraquinone [2,3-c:5,6-c' ] dipyrrole-1, 3,5,7(2H,6H) -tetraone, thiram oxide, thiazone, ferbam, mancozeb, maneb, metam, metiram (metaram or polyram), metiram-Zn, sodium metiram, propineb, thiram, metam (vapam or metam sodium), zineb, ziram, dimethyldisulfide, isoprothiolane, ethaboxam, trisethylphosphonic acid, fosetyl-Al or fosetyl-Al, methyl bromide, methyl iodide, methyl isothiocyanate, cyclamamide, methylfuroamide, validamycin, streptomycin, (2RS) -2-bromo-2- (bromomethyl) glutaronitrile (bromothalonil), dodecetin, dodecylguanidineacetate, biguanide, iminoctadine, octyltriacetate, 2,4-D, 2,4-DB, kasugamycin, metidine, fenhexamid, hymexazol, imazalil sulfate, imazalil, Imidazole, pefurazoate, prochloraz, triflumizole, imazaquin, boldo mixture, calcium polysulfide, copper acetate, copper carbonate, copper hydroxide, copper naphthenate, copper oleate, copper oxychloride, copper hydroxyquinoline, copper silicate, copper sulfate, copper fatty acid, cuprous oxide, sulfur, carbaryl, phthalide (or fthalide), pyrisoxazole (mycosphax), epirubine (fluorothiazolepyrithylin), carfentrazone, mandipropamid, KSF-1002, benzomorph, dimethomorph, fenpropimorph, tridemorph, dodemorph, diethofencarb, triphenyltin acetate, triphenyltin hydroxide, carboxin, fenamidone, oxazaquin, oxazalozoline, m-phenylphenol, p-phenylphenol, Tribromophenol (TBP), 2- [2- [ (7, 8-difluoro-2-methyl-3-quinolyl) oxy ] -6-fluoro-phenyl ] propane-2-one -alcohol, 2- [ 2-fluoro-6- [ (8-fluoro-2-methyl-3-quinolyl) oxy ] phenyl ] propan-2-ol, cyflufenamid, furflutolanil, oxadixyl, flutolanil, fenamido, iprothiamid, fenpiclonil, fludioxonil, pencycuron, edifenphos, iprobenfos, captafol, folpet, ethoprophos, fluazid, fenpropidin, hymexazol, 1-methylcyclopropene, 4-CPA, chlormequat, pyridazinoic acid, 2, 4-dipropionic acid, thionine, endothal, ethonium, ethephon, fluvalinamide, iprodione, gibberellin, hymexazol, malehydrazide, mepiquat, naphthylacetamide, paclobutrazol, prohexadione, thidiazuron, tribenuron (tributyl trithiophosphate), trithiofos, Trinexapac-ethyl, uniconazole, alpha-naphthylacetic acid, polyoxin D (polyoxin D or polyoxrim), BLAD, chitosan, cyanamide, folpet, 3- (difluoromethyl) -N-methoxy-1-methyl-N- [ 1-methyl-2- (2,4, 6-trichlorophenyl) ethyl ] pyrazole-4-carboxamide, bispyribac-sodium, fluxapyroxad, furametpyr, pyrazolonaphthiomide, penflufen, penthiopyrad, epoxiconazole, fenpyrazamide, pyridazone, pyribenzoxim-oxime, boscalid, fluopyram, difluorolin, fenarimol, 5-fluoro-2- (p-tolyl methoxy) pyrimidin-4-amine, pyrimethanone (dimetachlone or dimethaclone), dimethachlon, pyroquilon, propoxymine, ethoxyquin, quine, fluquinacrine, fluquindox, and, Quinoxyfen, 4,4, 5-trifluoro-3, 3-dimethyl-1- (3-quinolinyl) isoquinoline, 4, 4-difluoro-3, 3-dimethyl-1- (3-quinolinyl) isoquinoline, 5-fluoro-3, 3,4, 4-tetramethyl-1- (3-quinolinyl) isoquinoline, 9-fluoro-2, 2-dimethyl-5- (3-quinolinyl) -3H-1, 4-benzooxazepine, isobutoxyquinoline, oxolinic acid, imazamox (chinomethionate or oxythioquinol or quinoxymethenonate), spiroxamine, (E) -N-methyl-2- [2- (2, 5-dimethylphenoxymethyl) phenyl ] -2-methoxy-iminoacetamide, (mandiprin), azoxystrobin, coumoxystrobin, dimoxystrobin, enestroburin, fluoxastrobin, kresoxim-methyl, mandipropamid, metominostrobin, picoxystrobin, pyraclostrobin, clostrobilurin, trifloxystrobin, amisulbrom, dichlofluanid, tolylfluanid, but-3-alkynyl N- [6- [ [ (Z) - [ (1-methyltetrazol-5-yl) -phenyl-methylene ] amino ] oxymethyl ] -2-pyridinyl ] carbamate, dazomethyl, isotianil, tiadinil, thifluzamide, thiocyan (TCMTB), sulfenamide, zoxamide, prochloraz, tricyclazole, (+ -) -cis-1- (4-chlorophenyl) -2- (1H-1,2, 4-triazol-1-yl) -cycloheptanol (cyproconazole), 1- (5-bromo-2-pyridyl) -2- (2, 4-difluorophenyl) -1, 1-difluoro-3- (1,2, 4-triazol-1-yl) propan-2-ol, 2- (1-tert-butyl) -1- (2-chlorophenyl) -3- (1,2, 4-triazol-1-yl) -propan-2-ol (TCDP), azaconazole, bitertanol or biloxazol), bromuconazole, climbazole, cyproconazole, difenoconazole, dimeticonazole, diniconazole-M, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, cyproconazole, difenoconazole, flutriafol, epoxiconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, meperflutonazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, imidazoxazine, triticonazole, 2- [ [ (1R,5S) -5- [ (4-fluorophenyl) methyl ] -1-hydroxy-2, 2-dimethyl-cyclopentyl ] methyl ] -4H-1,2, 4-triazole-3-thione, 2- [ [3- (2-chlorophenyl) -2- (2, 4-difluorophenyl) oxiran-2-yl ] methyl ] -4H-1,2, 4-triazole-3-thione, cyprodinil (imid), Iprovalicarb, propamocarb, 2-benzyl-4-chlorophenol (benzylchlorophenol), allyl alcohol, azalidone, benzalkonium chloride, chloropicrin, cresol, dalargin, dichlorphen (dichlorophen or dichlorophene), oat bran, pyrithione, N- (2-p-chlorobenzoylethyl) -minium hexachloride, NNF-0721, octhioketone, rimsulfuron, propamidine, and propionic acid; or

An insecticide selected from abamectin, acephate, acetamiprid, sulfadiazine (S-1955), abamectin, azadirachtin, methyl glutethion, bifenthrin, diphenyl hydrazine, phenthoate, carbofuran, badan, chlorantraniliprole (DPX-E2Y45), chlorfenapyr, chlorfluazuron, chlorpyrifos-methyl, chromafenozide, clothianidin, cyflumetofen, cyfluthrin, beta-cyfluthrin, lambda-cyhalothrin, cypermethrin, cyromazine, deltamethrin, diafenthiuron, diazinon, dieldrin, pyrethrin, tetramethrin, dimethoate, dinotefuran, benaete, emamectin, endosulfan, fenvalerate, ethiprole, carbosulfan, fenoxycarb, fenpropathrin, pentathrin, flufenapyr, flonicamid, flufenapyr, fluvalinate, flubenflumethrin, cyhalothrin, fluvalicarb, fluvalinate, fluvalicarb, flubencarb, cy, Pyriminostrobin (UR-50701), flufenoxuron, chlorfenapyr hydrazide, hexaflumuron, hydramethylnon, imidacloprid, indoxacarb, isoxathion, lufenuron, malathion, metaflumizone, metaldehyde, methamidophos, methidathion, methomyl, methoprene, methoxychloride, metocloprid, methoxyfenozide, nitenpyram, nitro ethylurea thiazole, novaluron, noviflumuron (XDE-007), oxamyl, parathion-methyl, permethrin, phorate, vozapyr, phosmet, metafenozide, pirimicarb, profenofos, pyfluthrin, pymetrozine, pyrazinenitrile, pyrethrin, pyridalyl, 2060, chlorpyrifos, tebufenpyrad, fenugine, lanugine, ethosulfan, bsdinil, spirodiclofen (N-methyl 2060), thion, 2060, Tebufenozide, tefluthrin, terbufos, carbofuran, thiacloprid, thiamethoxam, thiodicarb, dimehypo, tralomethrin, triazamate, trichlorfon and chlorsulfuron; or

A bactericide selected from the group consisting of streptomycin; or

An acaricide selected from amitraz, chlorfenapyr, chlorobenzen, cyenopyrafen, cyhexatin, dicofol, dichlofenprox, etoxazole, fenazaquin, fenbutatin, fenpropathrin, fenpyroximate, hexythiazox, propargite, pyridaben and tebufenpyrad; or

A biological agent selected from the group consisting of bacillus thuringiensis, bacillus thuringiensis delta endotoxins, baculoviruses and entomopathogenic bacteria, viruses and fungi.

12. The fungicidal composition according to any preceding claim, wherein the composition further comprises an agriculturally acceptable carrier, and optionally a surfactant and/or a formulation aid.

13. A method for controlling or preventing phytopathogenic diseases, especially phytopathogenic fungi, on useful plants or propagation material thereof, which comprises applying a fungicidal composition as defined in any of claims 1 to 12 to the useful plants, the locus thereof or propagation material thereof.

14. The method of claim 13, wherein component (a) and component (B) of the composition are applied in a sequential manner.

15. A compound selected from

Or a compound selected from: