阅读说明：本技术 一种片剂粉末直压成型装置及方法 (Tablet powder direct-pressing forming device and method ) 是由 邵兴军 仲延龙 朱慧芬 沈井旺 周娟 马明明 毛日文 于 2021-08-12 设计创作，主要内容包括：本发明公开了一种片剂粉末直压成型装置及方法,包括支撑机构、上料机构和成型机构；所述支撑机构包括基台,所述基台上固定连接有支撑架；所述上料机构包括料仓,所述料仓固定连接在所述支撑架上,所述料仓下侧固定连通有进料管,所述进料管内部设置有拨料组件；所述成型机构包括固定台,所述固定台上开设有下料孔,所述固定台的上表面设置平面,所述固定台上侧设置有转盘,所述转盘的下表面和所述固定台的上表面固定连接。本发明在转轴上设置套管和弹性杆,在转轴转动时,可带动弹性杆击打连接架,从而使料仓轻微颤动,从而使堆积在料仓上侧的粉状物料落到料仓下侧,便于进料管下料；在不需要时弹性杆击打连接架,可将弹性杆收到套管中。(The invention discloses a tablet powder direct-pressing forming device and a tablet powder direct-pressing forming method, wherein the tablet powder direct-pressing forming device comprises a supporting mechanism, a feeding mechanism and a forming mechanism; the supporting mechanism comprises a base platform, and a supporting frame is fixedly connected to the base platform; the feeding mechanism comprises a bin, the bin is fixedly connected to the support frame, a feeding pipe is fixedly communicated with the lower side of the bin, and a material stirring assembly is arranged in the feeding pipe; the forming mechanism comprises a fixed table, a blanking hole is formed in the fixed table, the upper surface of the fixed table is provided with a plane, a turntable is arranged on the upper side of the fixed table, and the lower surface of the turntable is fixedly connected with the upper surface of the fixed table. According to the invention, the sleeve and the elastic rod are arranged on the rotating shaft, and when the rotating shaft rotates, the elastic rod can be driven to hit the connecting frame, so that the storage bin slightly vibrates, and therefore, powdery materials accumulated on the upper side of the storage bin fall to the lower side of the storage bin, and the feeding of the feeding pipe is facilitated; when the elastic rod is not needed, the connecting frame is hit by the elastic rod, and the elastic rod can be received in the sleeve.)

1. A tablet powder direct compression molding apparatus, comprising:

the supporting mechanism (1), the supporting mechanism (1) includes a base platform (11), the base platform (11) is fixedly connected with a supporting frame (12);

the feeding mechanism (2) comprises a bin (21), the bin (21) is fixedly connected to the support frame (12), a feeding pipe (22) is fixedly communicated with the lower side of the bin (21), and a material stirring assembly (23) is arranged in the feeding pipe (22);

the forming mechanism (3) comprises a fixed table (31), a blanking hole (311) is formed in the fixed table (31), a plane is arranged on the upper surface of the fixed table (31), a rotary table (32) is arranged on the upper side of the fixed table (31), the lower surface of the rotary table (32) is fixedly connected with the upper surface of the fixed table (31), forming holes (321) are formed in the rotary table (32), and the forming holes (321) are distributed in an annular equidistant mode relative to the axis of the rotary table (32);

forming mechanism (3) is including still including lifting and drop depression bar (33), the lower extreme fixedly connected with mounting panel (34) of lifting and drop depression bar (33), mounting panel (34) downside is connected with compresses tightly subassembly (35) and unloading subassembly (36).

2. The tablet powder direct compression molding device according to claim 1, wherein the material stirring assembly (23) comprises a motor (231), a base of the motor (231) is fixedly connected with a connecting frame (234), and the connecting frame (234) is fixedly connected to the outer wall of the storage bin (21);

the output fixedly connected with pivot (232) of motor (231), the circumference fixed surface of pivot (232) is connected with helical blade (233), the outward flange of helical blade (233) with the inner wall laminating of inlet pipe (22).

3. A tablet powder direct compression molding device according to claim 2, characterized in that a sleeve (24) is fixedly connected to the rotating shaft (232), and an elastic rod (25) is slidably arranged inside the sleeve (24);

the sleeve (24) is connected with a jacking screw (241) in a rotating mode through threads, the end portion of the jacking screw (241) extends into the sleeve (24), and the end portion of the jacking screw (241) is pressed and attached to the surface of the elastic rod (25).

4. A tablet powder direct compression molding apparatus as claimed in claim 3, wherein the elastic rod (25) is an elastic rubber rod, positioning holes (251) are equidistantly formed on the surface of the elastic rod (25), and the tightening screws (241) extend into the positioning holes (251).

5. A tablet powder direct compression molding apparatus according to claim 4, wherein the sleeve (24), the elastic rod (25) and the tightening screw (241) are provided in plurality, and the sleeve (24) is annularly and equidistantly distributed on the rotating shaft (232).

6. The tablet powder direct compression molding device according to claim 1, wherein the pressing assembly (35) comprises a first threaded barrel (351), the first threaded barrel (351) is embedded on the mounting plate (34) in a penetrating manner, a first threaded rod (352) is rotatably connected inside the first threaded barrel (351), a molding pressing block (353) is fixedly connected to the lower end of the first threaded rod (352), and a driving lever (354) is fixedly connected to the upper end of the first threaded rod (352).

7. The tablet powder direct compression molding device of claim 1, wherein the pressing assembly (35) further comprises a second threaded cylinder (355), the second threaded cylinder (355) is embedded in the mounting plate (34) in a penetrating manner, a second threaded rod (356) is rotatably connected inside the second threaded cylinder (355), an elastic member (357) is fixedly connected to the lower end of the second threaded rod (356), a pre-pressing block (358) is fixedly connected to the lower end of the elastic member (357), and a vent hole (3581) is formed in the pre-pressing block (358).

8. A tablet powder direct compression molding apparatus as claimed in claim 1, wherein the blanking assembly (36) comprises a vertical rod (361), and an elastic rubber layer (362) is fixedly connected to the lower end of the vertical rod (361);

a material receiving disc (363) is fixedly connected to the base platform (11), and the material receiving disc (363) is arranged on the lower side of the blanking hole (311).

9. The tablet powder direct compression molding device according to claim 1, wherein the turntable (32) is provided with a notch (322), and the distance from the side of the notch (322) close to the center of the turntable (32) is smaller than the distance from the molding hole (321) close to the center of the turntable (32).

10. A tablet powder direct compression molding method is characterized by comprising the following steps:

s1, placing the powdery raw material in a bin (21), and driving a helical blade (233) to rotate by a motor (231) through a rotating shaft (232), so that the powdery raw material is quantitatively conveyed into a forming hole (321); the sleeve (24) and the elastic rod (25) are arranged on the rotating shaft (232), and when the rotating shaft (232) rotates, the elastic rod (25) can be driven to hit the connecting frame (234), so that the storage bin (21) slightly vibrates, and the powdery material accumulated on the upper side of the storage bin (21) falls to the lower side of the storage bin (21), and the feeding of the feeding pipe (22) is facilitated; when the elastic rod (25) strikes the connecting frame (234) when not needed, the elastic rod (25) can be received in the sleeve (24);

s2, the lifting pressure lever (33) drives the mounting plate (34) to descend, the mounting plate (34) is provided with a compaction assembly (35), and the elastic piece (357) and the prepressing pressing block (358) preliminarily press and form the powdery raw materials, so that air in the powder gap is discharged from the vent hole (3581);

s3, rotating the turntable (32) to enable the tablet medicament subjected to pre-pressing forming to reach the lower side of the forming pressing block (353), and further pressing and forming the forming pressing block (353); when the flaky medicament with different thicknesses needs to be molded, the first threaded rod (352) can be rotated to enable the molding pressing block (353) to ascend or descend;

s4, the turntable (32) rotates to enable the pressed and formed tablet medicament to reach the lower side of the blanking assembly (36), and the blanking assembly (36) extends into the forming hole (321) under the driving of the mounting plate (34), so that the tablet medicament is pressed downwards and falls into the receiving tray (363) through the blanking hole (311);

s5, placing the cleaning tool into the notch (322) at intervals, and driving the cleaning tool to clean the powder residue on the fixed table (31) by rotating the turntable (32).

Technical Field

The invention relates to the technical field of tablet powder direct compression molding, in particular to a tablet powder direct compression molding device and method.

Background

The preparation process of the tablet mainly comprises several methods such as wet granulation tabletting, dry granulation tabletting, direct powder tabletting and freeze-drying tabletting. The direct powder compression is to directly compress the medicine powder and proper auxiliary materials into tablets without granulation (wet granules or dry granules) after sieving and mixing the medicine powder and the proper auxiliary materials respectively. Because the process is simple, granulation and drying are not needed, energy and time are saved, the stability of the medicine is protected, the dissolution rate of the medicine is improved, the industrial automation degree is high, and the like, the method is increasingly adopted by pharmaceutical enterprises of various countries.

The existing tablet powder forming device is not convenient to exhaust air in powder raw materials, so that the formed tablet is not firm; the material is easy to block during feeding.

Disclosure of Invention

Technical problem to be solved

The invention can solve the problem of low single-channel detection mode efficiency of the existing test strip fluorescence detection device.

(II) technical scheme

In order to achieve the above object, the present invention adopts the following technical solution, and an apparatus for direct compression molding of tablet powder comprises:

the supporting mechanism comprises a base station, and a supporting frame is fixedly connected to the base station;

the feeding mechanism comprises a bin, the bin is fixedly connected to the support frame, a feeding pipe is fixedly communicated with the lower side of the bin, and a material stirring assembly is arranged in the feeding pipe;

the forming mechanism comprises a fixed table, a blanking hole is formed in the fixed table, the upper surface of the fixed table is provided with a plane, a turntable is arranged on the upper side of the fixed table, the lower surface of the turntable is fixedly connected with the upper surface of the fixed table, forming holes are formed in the turntable, and the forming holes are distributed in an annular equidistant mode relative to the axis of the turntable;

the forming mechanism comprises a lifting compression rod, a mounting plate is fixedly connected to the lower end of the lifting compression rod, and a pressing assembly and a blanking assembly are connected to the lower side of the mounting plate.

As a preferred technical scheme of the invention, the material shifting assembly comprises a motor, a base of the motor is fixedly connected with a connecting frame, and the connecting frame is fixedly connected to the outer wall of the storage bin;

the output fixedly connected with pivot of motor, the circumference fixed surface of pivot is connected with helical blade, helical blade's outward flange with the inner wall laminating of inlet pipe.

As a preferred technical scheme of the invention, a sleeve is fixedly connected to the rotating shaft, and an elastic rod is arranged in the sleeve in a sliding manner;

the sleeve is connected with a jacking screw in a rotating mode through threads, the end portion of the jacking screw extends into the sleeve, and the end portion of the jacking screw is tightly pressed and attached to the surface of the elastic rod.

As a preferred technical solution of the present invention, the elastic rod is an elastic rubber rod, positioning holes are equidistantly formed in the surface of the elastic rod, and the tightening screw extends into the positioning holes.

As a preferable technical scheme of the invention, the sleeve, the elastic rod and the jacking screw are all provided with a plurality of sleeves, and the sleeves are distributed on the rotating shaft in an annular and equidistant manner.

As a preferred technical scheme of the present invention, the pressing assembly includes a first threaded cylinder, the first threaded cylinder is inserted into the mounting plate, a first threaded rod is rotatably connected to the inside of the first threaded cylinder, a forming press block is fixedly connected to the lower end of the first threaded rod, and a shift lever is fixedly connected to the upper end of the first threaded rod.

As a preferred technical scheme of the present invention, the pressing assembly further includes a second threaded cylinder, the second threaded cylinder is inserted into the mounting plate, a second threaded rod is rotatably connected inside the second threaded cylinder, an elastic member is fixedly connected to a lower end of the second threaded rod, a pre-pressing block is fixedly connected to a lower end of the elastic member, and a vent hole is formed in the pre-pressing block.

As a preferred technical scheme of the invention, the blanking assembly comprises an upright rod, wherein the lower end of the upright rod is fixedly connected with an elastic rubber layer;

fixedly connected with take-up pan on the base station, the take-up pan sets up the downside in unloading hole.

As a preferable technical scheme of the present invention, the turntable is provided with a notch, and a distance from one side of the notch close to the center of the turntable is smaller than a distance from the forming hole close to the center of the turntable.

A tablet powder direct compression molding method comprises the following steps:

s1, placing the powdery raw material in a bin, and driving a helical blade to rotate by a motor through rotation of a rotating shaft so as to quantitatively convey the powdery raw material to a forming hole; the sleeve and the elastic rod are arranged on the rotating shaft, and when the rotating shaft rotates, the elastic rod can be driven to hit the connecting frame, so that the storage bin slightly vibrates, and the powdery material accumulated on the upper side of the storage bin falls to the lower side of the storage bin, and the feeding of the feeding pipe is facilitated; when the elastic rod is not needed, the connecting frame is hit by the elastic rod, and the elastic rod can be received in the sleeve;

s2, the lifting pressure rod drives the mounting plate to descend, the mounting plate is provided with a compaction assembly, and the elastic piece and the pre-compaction pressing block preliminarily press and form the powdery raw material, so that air in the powder gap is discharged from the vent hole;

s3, rotating the turntable to enable the tablet medicament subjected to pre-pressing forming to reach the lower side of the forming pressing block, and further pressing and forming the forming pressing block; when flaky medicaments with different thicknesses are required to be molded, the first threaded rod can be rotated to enable the molding pressing block to ascend or descend;

s4, rotating the turntable to enable the pressed and formed flaky medicament to reach the lower side of the blanking assembly, and driving the blanking assembly to extend into the forming hole under the driving of the mounting plate, so that the flaky medicament is pressed downwards and falls into the receiving disc through the blanking hole;

s5, placing the cleaning tool into the notch at intervals, and driving the cleaning tool to clean the powder residue on the fixing table by rotating the turntable.

(III) advantageous effects

Putting the powdery raw material into a bin, and driving a helical blade to rotate by a motor through rotation of a rotating shaft so as to quantitatively convey the powdery raw material into a forming hole; the sleeve and the elastic rod are arranged on the rotating shaft, and when the rotating shaft rotates, the elastic rod can be driven to hit the connecting frame, so that the storage bin slightly vibrates, and the powdery material accumulated on the upper side of the storage bin falls to the lower side of the storage bin, and the feeding of the feeding pipe is facilitated; when the elastic rod is not needed, the connecting frame is hit by the elastic rod, and the elastic rod can be received in the sleeve;

the mounting plate is provided with the compaction assembly, and the elastic piece and the pre-pressing block preliminarily press and form the powdery raw material, so that air in powder gaps is discharged from the vent holes, and the subsequent forming is firmer;

the turntable rotates to enable the pre-pressed and formed flaky medicament to reach the lower side of the forming press block, and the forming press block is further pressed and formed; when flaky medicaments with different thicknesses are required to be molded, the first threaded rod can be rotated to enable the molding pressing block to ascend or descend.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.

FIG. 1 is a schematic front view of the present invention;

FIG. 2 is a schematic view of the interior of the feed mechanism of the present invention;

FIG. 3 is a cross-sectional top view of portion A-A of FIG. 2 of the present invention;

FIG. 4 is a schematic top view of the cannula and resilient stem portion of the present invention;

FIG. 5 is an enlarged schematic view of portion B of FIG. 1 of the present invention;

FIG. 6 is an enlarged schematic view of section C of FIG. 1 of the present invention;

fig. 7 is a schematic top view of the turntable of the present invention.

In the figure: 1. a support mechanism; 11. a base station; 12. a support frame; 2. a feeding mechanism; 21. a storage bin; 22. a feed pipe; 23. a material poking component; 3. a molding mechanism; 31. a fixed table; 311. a blanking hole; 32. a turntable; 321. forming holes; 33. a lifting pressure lever; 34. mounting a plate; 35. a compression assembly; 36. a blanking assembly; 231. a motor; 232. a rotating shaft; 233. a helical blade; 234. a connecting frame; 24. a sleeve; 25. an elastic rod; 241. jacking the screw tightly; 251. positioning holes; 351. a first threaded barrel; 352. a first threaded rod; 353. forming and pressing blocks; 354. a deflector rod; 355. a second threaded barrel; 356. a second threaded rod; 357. an elastic member; 358. prepressing a pressing block; 3581. a vent hole; 361. erecting a rod; 362. an elastic rubber layer; 363. a take-up pan; 322. and (4) a notch.

The implementation, functional features and advantages of the objects of the present invention will be further explained with reference to the accompanying drawings.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings of the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.

In the description of the present invention, it is to be understood that the terms "longitudinal", "upper", "lower", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.

As shown in fig. 1-7, a tablet powder direct compression molding apparatus comprises a supporting mechanism 1, a feeding mechanism 2 and a molding mechanism 3;

the supporting mechanism 1 comprises a base platform 11, and a supporting frame 12 is fixedly connected to the base platform 11;

the feeding mechanism 2 comprises a bin 21, the bin 21 is fixedly connected to the support frame 12, a feeding pipe 22 is fixedly communicated with the lower side of the bin 21, and a material stirring assembly 23 is arranged inside the feeding pipe 22;

illustratively, the material stirring assembly 23 includes a motor 231, a base of the motor 231 is fixedly connected with a connecting frame 234, and the connecting frame 234 is fixedly connected to an outer wall of the storage bin 21;

the output fixedly connected with pivot 232 of motor 231, the circumferential surface fixed connection of pivot 232 is connected with helical blade 233, the outward flange of helical blade 233 with the inner wall laminating of inlet pipe 22.

Preferably, a sleeve 24 is fixedly connected to the rotating shaft 232, and an elastic rod 25 is slidably arranged inside the sleeve 24;

the sleeve 24 is rotatably connected with a tightening screw 241 through a thread, the end of the tightening screw 241 extends into the sleeve 24, and the end of the tightening screw 241 is pressed and attached to the surface of the elastic rod 25.

Preferably, the elastic rod 25 is an elastic rubber rod, positioning holes 251 are equidistantly formed in the surface of the elastic rod 25, and the tightening screws 241 extend into the positioning holes 251.

Preferably, the sleeve 24, the elastic rod 25 and the tightening screw 241 are all provided in plurality, and the sleeve 24 is arranged on the rotating shaft 232 in an annular and equidistant manner.

The forming mechanism 3 comprises a fixed table 31, a blanking hole 311 is formed in the fixed table 31, a plane is arranged on the upper surface of the fixed table 31, a turntable 32 is arranged on the upper side of the fixed table 31, the lower surface of the turntable 32 is fixedly connected with the upper surface of the fixed table 31, forming holes 321 are formed in the turntable 32, and the forming holes 321 are distributed in an annular equidistant manner relative to the axis of the turntable 32;

the forming mechanism 3 comprises a lifting compression rod 33, a mounting plate 34 is fixedly connected to the lower end of the lifting compression rod 33, and a pressing assembly 35 and a blanking assembly 36 are connected to the lower side of the mounting plate 34.

A notch 322 is formed in the turntable 32, and the distance from one side of the notch 322 close to the center of the turntable 32 is smaller than the distance from the forming hole 321 close to the center of the turntable 32.

The cleaning tool is placed in the notch 322, and the turntable 32 rotates to drive the cleaning tool to clean the powder residue on the fixing table 31.

The pressing assembly 35 includes a first threaded cylinder 351, the first threaded cylinder 351 is inserted into the mounting plate 34, a first threaded rod 352 is rotatably connected to the inside of the first threaded cylinder 351, a forming pressing block 353 is fixedly connected to the lower end of the first threaded rod 352, and a driving lever 354 is fixedly connected to the upper end of the first threaded rod 352.

The pressing assembly 35 further includes a second threaded cylinder 355, the second threaded cylinder 355 is inserted into the mounting plate 34, a second threaded rod 356 is rotatably connected inside the second threaded cylinder 355, an elastic member 357 is fixedly connected to a lower end of the second threaded rod 356, a pre-pressing block 358 is fixedly connected to a lower end of the elastic member 357, and a vent 3581 is formed in the pre-pressing block 358.

For example, the elastic member 357 may be a spring or a spring.

The blanking component 36 comprises a vertical rod 361, and an elastic rubber layer 362 is fixedly connected to the lower end of the vertical rod 361;

a receiving tray 363 is fixedly connected to the base 11, and the receiving tray 363 is arranged at the lower side of the blanking hole 311.

A tablet powder direct compression molding method comprises the following steps:

s1, placing the powdery raw material in the bin 21, and driving the helical blade 233 to rotate by the rotation of the motor 231 through the rotating shaft 232, so that the powdery raw material is quantitatively conveyed into the forming hole 321; the sleeve 24 and the elastic rod 25 are arranged on the rotating shaft 232, and when the rotating shaft 232 rotates, the elastic rod 25 can be driven to hit the connecting frame 234, so that the storage bin 21 slightly vibrates, and the powdery material accumulated on the upper side of the storage bin 21 falls to the lower side of the storage bin 21, so that the feeding of the feeding pipe 22 is facilitated; when not needed, the elastic rod 25 strikes the connecting frame 234, and the elastic rod 25 can be received in the sleeve 24;

s2, the lifting pressure rod 33 drives the mounting plate 34 to descend, the compacting assembly 35 is arranged on the mounting plate 34, the elastic piece 357 and the pre-pressing compact 358 preliminarily press and form the powdery raw material, and therefore air in the powder gap is discharged from the vent 3581;

s3, rotating the turntable 32 to enable the tablet medicament subjected to pre-pressing forming to reach the lower side of the forming pressing block 353, and further pressing and forming the forming pressing block 353; when flaky medicaments with different thicknesses need to be molded, the first threaded rod 352 can be rotated to enable the molding pressing block 353 to ascend or descend;

s4, rotating the turntable 32 to make the pressed tablet reach the lower side of the blanking assembly 36, and under the driving of the mounting plate 34, the blanking assembly 36 extends into the forming hole 321 to press the tablet downwards to make the tablet fall into the receiving tray 363 through the blanking hole 311;

s5, placing the cleaning tool into the notch 322 at intervals, and rotating the turntable 32 to drive the cleaning tool to clean the powder residue on the fixed table 31.

Illustratively, the device and the method can be used for producing selenium vitamin C vitamin E tablets, and the main raw materials comprise selenium-enriched yeast, vitamin C and vitamin E; the adjuvants include microcrystalline cellulose, lactose, silicon dioxide, magnesium stearate, fructus Citri sinensis essence, aspartame, lemon yellow aluminum lake, and sunset yellow aluminum lake.

The formula proportion and the quality standard of the raw materials and the auxiliary materials are as follows:

selenium-rich yeast: 17 percent of

Implementing the national drug Standard WS1- (x-005) -99Z selenium Yeast Se (in Se, ug);

vitamin E50% and powder 12%

Executing GB 14756: "vitamin E (dl-alpha-tocopherol acetate)," vitamin E (mg, in terms of d-alpha-tocopherol ");

vitamin C: 5.5 percent

Executing vitamin C (in terms of L-ascorbic acid, mg) of GB14754 vitamin C (ascorbic acid);

microcrystalline cellulose (PH 102): 35.25 percent

GB 1886.103-2015 food additive appointed standard food additive microcrystalline cellulose is executed;

lactose (direct compression): 27.445 percent

Reference is made to GB 25595 national standards lactose for food safety or pharmacopoeia of the people's republic of China;

silicon dioxide: 1 percent of

Reference is made to GB 25576 national food safety standard, namely, silicon dioxide as a food additive; silicon dioxide in the current pharmacopoeia of the people's republic of China;

magnesium stearate: 0.5 percent

Reference GB 1886.91 national food safety Standard food additive magnesium stearate; magnesium stearate in the current pharmacopoeia of the people's republic of China;

sweet orange essence: 1 percent of

Reference GB 2760;

aspartame: 0.25 percent

Reference GB 2760;

lemon yellow aluminum lake: 0.025%

Reference GB 2760;

sunset yellow aluminum lake: 0.030%

Reference is made to GB 2760.

The production of the above-mentioned medicament is merely illustrative and not limitative of the present invention, and the present device can also be used for processing other tablets.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.