用于无创胚胎移植优先级评级的系统和方法

文档序号:831801 发布日期:2021-03-30 浏览:7次 >En<

阅读说明:本技术 用于无创胚胎移植优先级评级的系统和方法 (System and method for non-invasive embryo transfer priority rating ) 是由 邹央云 姚雅馨 陆思嘉 薄世平 夏滢颖 于 2020-07-21 设计创作,主要内容包括:本发明为用于无创胚胎移植优先级评级的系统和方法,提供生物特征和生物特征的组合,其可用于基于胚胎培养液和/或囊胚腔液的胚胎整倍体概率预测和胚胎植入优先级的评级。本发明还涉及将这些生物特征的量值输入分类系统例如随机森林以预测胚胎整倍体概率的方法,以及利用该胚胎整倍体概率来评级胚胎的植入优先级的方法。本发明也提供包含用于确定所述生物特征和生物特征组合的试剂在本发明预测和评级方法中的应用、以及用于所述预测方法和评级方法的系统和计算机程序产品。(The present invention provides a combination of biological features and biological characteristics useful for embryo euploid probability prediction and embryo implantation priority ranking based on embryo culture fluid and/or blastocoel fluid. The invention also relates to a method of inputting the magnitudes of these biological characteristics into a classification system, such as a random forest, to predict embryo euploid probabilities, and a method of using the embryo euploid probabilities to rank the implantation priority of embryos. The invention also provides for the use of agents comprising combinations for determining said biological features and biological features in the prediction and rating methods of the invention, as well as systems and computer program products for use in said prediction methods and rating methods.)

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