阅读说明：本技术 一种中医外用软膏贴及其制备方法和应用 (Traditional Chinese medicine external ointment paste and preparation method and application thereof ) 是由 付宝麟 于 2021-08-26 设计创作，主要内容包括：本发明公开了一种中医外用软膏贴及其制备方法和应用,软膏贴由以下质量份数的组分制成：薄荷脑油7.5-8.5份,重楼6.5-7.5份,白芨4.5-5.5份,白芷4.5-5.5份,土荆皮4.5-5.5份,麝香4.5-5.5份,田螺壳4.5-5.5份,红霉素4.5-5.5份,消炎粉4.5-5.5份,载体45-55份；其由以下步骤制成：S1、称取上述原料；S2、将田螺壳加热后研磨并过筛得到炙田螺壳粉,将红霉素研磨后过筛得到红霉素粉,将除载体外的其余原料均打碎混合并,过100目筛,与炙田螺壳粉、红霉素粉混合均匀,得到第一混合物,将第一混合物加入载体中搅拌均匀得到第二混合物；S3、将第二混合物均匀涂抹在空白膏贴上,得到中医外用软膏贴。本发明公开的中医外用软膏贴具有消炎镇痛、排毒等作用,对阑尾炎及恶性肿瘤如癌症等具有很好的治疗效果。(The invention discloses an external traditional Chinese medicine ointment paste and a preparation method and application thereof, wherein the ointment paste is prepared from the following components in parts by mass: 7.5-8.5 parts of menthol oil, 6.5-7.5 parts of rhizoma paridis, 4.5-5.5 parts of bletilla striata, 4.5-5.5 parts of angelica dahurica, 4.5-5.5 parts of golden larch bark, 4.5-5.5 parts of musk, 4.5-5.5 parts of viviparidae shell, 4.5-5.5 parts of erythromycin, 4.5-5.5 parts of anti-inflammatory powder and 45-55 parts of carrier; the method comprises the following steps: s1, weighing the raw materials; s2, heating the river snail shells, grinding and sieving to obtain roasted river snail shell powder, grinding and sieving erythromycin to obtain erythromycin powder, crushing and mixing the other raw materials except the carrier, sieving by a 100-mesh sieve, uniformly mixing the raw materials with the roasted river snail shell powder and the erythromycin powder to obtain a first mixture, adding the first mixture into the carrier, and uniformly stirring to obtain a second mixture; s3, uniformly smearing the second mixture on the blank plaster to obtain the traditional Chinese medicine external ointment plaster. The traditional Chinese medicine external ointment paste disclosed by the invention has the effects of diminishing inflammation, easing pain, expelling toxin and the like, and has a good treatment effect on appendicitis and malignant tumors such as cancer and the like.)

1. The traditional Chinese medicine external ointment patch is characterized by being prepared from the following components in parts by mass:

7.5-8.5 parts of menthol oil, 6.5-7.5 parts of rhizoma paridis, 4.5-5.5 parts of bletilla striata, 4.5-5.5 parts of angelica dahurica, 4.5-5.5 parts of golden larch bark, 4.5-5.5 parts of musk, 4.5-5.5 parts of viviparidae shell, 4.5-5.5 parts of erythromycin, 4.5-5.5 parts of anti-inflammatory powder and 45-55 parts of carrier.

2. The traditional Chinese medicine ointment patch for external use according to claim 1, wherein the musk is artificial musk.

3. The traditional Chinese medicine ointment patch for external use according to claim 1, wherein the anti-inflammatory powder is sulfonamide anti-inflammatory powder.

4. The topical ointment patch of traditional Chinese medicine according to claim 1, wherein the carrier is petrolatum.

5. A method for preparing the traditional Chinese medicine ointment patch for external use according to claim 1, which is characterized by comprising the following steps:

s1, weighing the following raw materials in parts by weight:

7.5-8.5 parts of menthol oil, 6.5-7.5 parts of rhizoma paridis, 4.5-5.5 parts of bletilla striata, 4.5-5.5 parts of angelica dahurica, 4.5-5.5 parts of golden larch bark, 4.5-5.5 parts of musk, 4.5-5.5 parts of viviparidae shell, 4.5-5.5 parts of erythromycin, 4.5-5.5 parts of anti-inflammatory powder and 45-55 parts of carrier;

s2, heating the escargot shells at the temperature of 150-220 ℃ until the surfaces of the escargot shells turn brown, grinding the escargot shells and sieving the ground escargot shells through a 100-mesh sieve to obtain roasted escargot shell powder, grinding the erythromycin and sieving the erythromycin through the 100-mesh sieve to obtain erythromycin powder, crushing the mint naphtha, the paris polyphylla, the bletilla striata, the angelica dahurica, the golden larch bark and the musk, mixing the crushed mint naphtha, the crushed substances with the inflammation diminishing powder, sieving the smashed mint naphtha, the smashed escargot shell powder and the erythromycin powder through the 100-mesh sieve to obtain a first mixture, adding the first mixture into the carrier, and uniformly stirring the first mixture to obtain a second mixture;

s3, uniformly smearing the second mixture on a blank plaster to obtain the traditional Chinese medicine external ointment plaster.

6. The method for preparing a traditional Chinese medicine ointment patch for external use according to claim 5, wherein a plurality of air holes are formed in the surface of the blank ointment patch.

7. An application of the topical ointment of claim 1 in treating appendicitis and malignant tumor.

8. An oral anti-inflammatory tea used in combination with the traditional Chinese medicine external ointment patch of claim 1 is characterized by being prepared from the following components in parts by mass:

5-10 parts of radix tetrastigme, 1.8-2.2 parts of lysimachia christinae hance, 1.8-2.2 parts of wild chrysanthemum flower and 1.4-1.6 parts of licorice.

9. The use method of the oral anti-inflammatory tea according to claim 8, comprising the steps of:

step A, weighing the following raw materials in parts by weight:

5-10 parts of radix tetrastigme, 1.8-2.2 parts of lysimachia christinae hance, 1.8-2.2 parts of wild chrysanthemum and 1.4-1.6 parts of liquorice;

step B, soaking the raw materials in the step A for 3-5min by using 1000 parts of water with the temperature of more than 96 ℃ to obtain tea soup, and drinking the tea soup;

and C, repeating the step B1 times every 4-6h, and repeating the steps 3-7 times in total.

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to an external traditional Chinese medicine ointment paste and a preparation method and application thereof.

Background

Appendicitis is an inflammatory change caused by various factors, is a common surgical disease and is most common in young years. The existing appendicitis treatment modes are mainly divided into two categories of non-operative treatment and operative treatment. Surgical treatment, although it can eradicate appendicitis, carries a certain risk and can cause patients to have inconvenience and suffering for a long time; the existing non-operative treatment mode generally takes a large amount of antibiotics to relieve or eliminate inflammation, but on one hand, the method still treats the symptoms and the root causes, and the disease is easy to relapse once the medicine is stopped; on the other hand, it will cause a large burden on the body of the patient, especially on the organs such as the kidney.

Cancer is a common malignant tumor, and in the past of medical technology's failure, cancer is essentially equivalent to the declared death. With the continuous development of medical technology, more and more medical means for effectively treating cancer are available, wherein chemotherapy and radiotherapy are the most typical. However, the large amount of chemical drugs to be taken during chemotherapy or the large dose of radiation to be born during radiotherapy can cause serious influence on the body of the patient, and the patient suffers from serious pain.

Moreover, it can be seen from the above that antibiotic therapy, surgical therapy, and chemotherapy and radiotherapy, which are commonly used for treating appendicitis, and cancer, are typical western medicine approaches. In fact, the application of the traditional Chinese medicine technology in the above fields is well documented.

In summary, there is an urgent need for a Chinese medicine with less pain and obvious effect for patients to relieve the pain of patients caused by appendicitis, cancer and other diseases and to have good therapeutic effect on these diseases.

Disclosure of Invention

Therefore, the embodiment of the invention provides a traditional Chinese medicine external ointment paste and a preparation method and application thereof, and aims to solve the problems in the prior art.

In order to achieve the above object, the embodiments of the present invention provide the following technical solutions:

in a first aspect, the embodiment of the invention provides a traditional Chinese medicine external ointment patch which is prepared from the following components in parts by mass:

7.5-8.5 parts of menthol oil, 6.5-7.5 parts of rhizoma paridis, 4.5-5.5 parts of bletilla striata, 4.5-5.5 parts of angelica dahurica, 4.5-5.5 parts of golden larch bark, 4.5-5.5 parts of musk, 4.5-5.5 parts of viviparidae shell, 4.5-5.5 parts of erythromycin, 4.5-5.5 parts of anti-inflammatory powder and 45-55 parts of carrier.

Preferably, the musk is an artificial musk.

Preferably, the carrier is petrolatum.

Preferably, the anti-inflammatory powder is sulfonamide anti-inflammatory powder.

In a second aspect, an embodiment of the present invention provides a method for preparing the above external traditional Chinese medicine ointment patch, including the following steps:

s1, weighing the following raw materials in parts by weight:

7.5-8.5 parts of menthol oil, 6.5-7.5 parts of rhizoma paridis, 4.5-5.5 parts of bletilla striata, 4.5-5.5 parts of angelica dahurica, 4.5-5.5 parts of golden larch bark, 4.5-5.5 parts of musk, 4.5-5.5 parts of viviparidae shell, 4.5-5.5 parts of erythromycin, 4.5-5.5 parts of anti-inflammatory powder and 45-55 parts of carrier;

s2, heating the escargot shells at 220 ℃ below 150 ℃ to enable the surfaces of the escargot shells to be brown, grinding the escargot shells and sieving the ground escargot shells through a 100-mesh sieve to obtain roasted escargot shell powder, grinding erythromycin and sieving the erythromycin through the 100-mesh sieve to obtain erythromycin powder, crushing the menthol oil, the paris polyphylla, the bletilla striata, the radix angelicae, the golden larch bark and the musk, mixing the crushed substances with the anti-inflammatory powder, sieving the crushed substances through the 100-mesh sieve, uniformly mixing the crushed substances with the roasted escargot shell powder and the erythromycin powder to obtain a first mixture, adding the first mixture into a carrier, and uniformly stirring the mixture to obtain a second mixture;

s3, uniformly smearing the second mixture on the blank plaster to obtain the traditional Chinese medicine external ointment plaster.

Preferably, the surface of the blank plaster is provided with a plurality of air holes.

In a third aspect, the embodiment of the invention provides the application of the traditional Chinese medicine external ointment paste in treating appendicitis, malignant tumors and cancers.

In a fourth aspect, the embodiment of the invention provides an oral anti-inflammatory tea used in combination with the traditional Chinese medicine external ointment patch, which is prepared from the following components in parts by mass:

5-10 parts of radix tetrastigme, 1.8-2.2 parts of lysimachia christinae hance, 1.8-2.2 parts of wild chrysanthemum flower and 1.4-1.6 parts of licorice.

In a fifth aspect, the embodiment of the invention provides a use method of the oral anti-inflammatory tea, which comprises the following steps:

step A, weighing the following raw materials in parts by weight:

5-10 parts of radix tetrastigme, 1.8-2.2 parts of lysimachia christinae hance, 1.8-2.2 parts of wild chrysanthemum and 1.4-1.6 parts of liquorice;

step B, soaking the raw materials in the step A for 3-5min by using 500-1000 parts of water with the temperature of more than 96 ℃ to obtain tea soup, and drinking the tea soup;

and C, repeating the step B1 times every 4-6h, and repeating the steps 3-7 times in total.

Compared with the prior art, the invention has at least the following beneficial effects:

(1) the traditional Chinese medicine external ointment paste provided by the embodiment of the invention has very good treatment effects on appendicitis, tumor and cancer, swelling and pain in brain, lumbar tuberculosis, gastric ulcer, bone necrosis, various tumor abscess bags and the like, can quickly stop pain and ulcer, and has a mild medicinal effect and an obvious effect.

(2) The traditional Chinese medicine ointment patch for external use provided by the embodiment of the invention has the advantages of rigorous compatibility of the prescription, mutual promotion and synergistic effect among all the medicinal materials, obvious anti-inflammatory and analgesic effects, no toxic or side effect on a human body, no need of oral administration and almost no harm to the human body.

(3) The traditional Chinese medicine external ointment paste provided by the embodiment of the invention has the advantages of small dosage, small medicine types, easy carrying of various medicinal materials, simple and quick manufacturing method, small limitation by appliances, places and environments, capability of quickly emergent sudden onset self-rescue or rescue of patients with sudden onset of illness, suitability for various occasions such as hospitals, families, disaster relief sites, field first-aid and the like, and high popularization value.

(4) The traditional Chinese medicine external ointment patch provided by the embodiment of the invention can be used together with the oral anti-inflammatory tea provided by the embodiment of the invention, can be used internally and externally, can supplement each other, and has very obvious promotion effect on the drug effects of the oral anti-inflammatory tea and the oral anti-inflammatory tea.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail with reference to specific embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

In the description of the present invention, "a plurality" means two or more unless otherwise specified. The terms "first," "second," "third," "fourth," and the like (if any) in the description and in the claims of the present invention are intended to distinguish between the referenced items. For a scheme with a time sequence flow, the term expression does not need to be understood as describing a specific sequence or a sequence order, and for a scheme of a device structure, the term expression does not have distinction of importance degree, position relation and the like.

Furthermore, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements specifically listed, but may include other steps or elements not expressly listed that are inherent to such process, method, article, or apparatus or that are added to such process, method, article, or apparatus based on the optimization concepts of the present invention.

Examples 1 to 3 respectively provide a traditional Chinese medicine ointment patch for external use, which comprises the following components in parts by mass as shown in table 1 below:

table 1-examples 1-3 provide the components of the topical Chinese medicinal plaster in parts by mass

The preparation method of the traditional Chinese medicine external ointment patch provided in embodiment 1 comprises the following steps:

s1, weighing the following raw materials in parts by weight:

7.5 parts of menthol oil, 6.5 parts of paris polyphylla, 4.5 parts of bletilla striata, 4.5 parts of angelica dahurica, 4.5 parts of golden larch bark, 4.5 parts of musk, 4.5 parts of escargots shell, 4.5 parts of erythromycin, 4.5 parts of sulfanilamide anti-inflammatory powder and 45 parts of carrier;

s2, heating the river snail shells at 220 ℃ until the surfaces of the river snail shells turn brown, grinding the river snail shells and sieving the ground river snail shells with a 100-mesh sieve to obtain fried river snail shell powder, grinding the erythromycin in S1 and sieving the ground river snail shell powder with the 100-mesh sieve to obtain erythromycin powder, crushing the menthol oil, the rhizoma paridis, the bletilla striata, the radix angelicae, the golden larch bark and the musk, mixing the smashed mint oil, the smashed rhizoma paridis, the smashed rhizoma bletillae, the smashed radix angelicae, the golden larch bark and the musk with sulfanilamide type anti-inflammatory powder, sieving the smashed mint oil with the 100-mesh sieve, uniformly mixing the smashed mint oil, the rhizoma paridis, the dahurian angelica sinensis, the golden larch bark and the musk with roasted river snail shell powder and the erythromycin powder to obtain a first mixture, adding the first mixture into a carrier, and uniformly stirring the first mixture to obtain a second mixture;

s3, uniformly smearing the second mixture on a blank plaster with a plurality of holes on the surface to obtain the traditional Chinese medicine external ointment plaster.

Examples 2 to 3 provide a method for preparing a topical plaster of chinese medicine in the same manner as in example 1.

In the treatment of appendicitis, the application method of the traditional Chinese medicine external ointment patch provided in example 1 is as follows:

before use, the epidermis of the pain part of the patient is cleaned, cleaned and wiped dry, and 100g of the second mixture prepared in example 1 is prepared into a traditional Chinese medicine ointment patch for external use, and the traditional Chinese medicine ointment patch is pasted on the epidermis. Changing the medicine 1-2 times daily, and 5-7 days as a course of treatment, and determining the number of the course of treatment according to the situation.

In the treatment of swelling and pain in the brain, tuberculosis of lumbar vertebrae, gastric ulcer, necrosis of bone, malignant tumor, gastric cancer, lung cancer, liver cancer and other cancers, abscess, etc., the application method of the traditional Chinese medicine external ointment patch provided in example 1 is as follows:

taking a proper amount of the second mixture prepared in the embodiment 1 according to the size of the affected part to prepare a traditional Chinese medicine external ointment paste, wherein the ointment paste can completely cover the affected part; the topical ointment of example 1 was applied to the affected part after the patient had cleaned and dried, and the dressing was changed 1 time a day. 5-7 days as a course of treatment, and the number of the course of treatment is determined according to the situation; the sepsis can be pulled out after the ointment paste is used for some diseases, and the wound can be automatically healed only by cleaning the wound when the sepsis is drained and stopping taking the ointment for 2-5 days as the case may be.

Examples 2 to 3 provide a method of using the external traditional Chinese medicine ointment patch in the same manner as in example 1.

Examples 1 to 3 also provide oral anti-inflammatory tea used in combination with the traditional Chinese medicine ointment patch, wherein the following components are shown in table 2:

TABLE 2-quality parts of the components of oral anti-inflammatory tea provided in examples 1-3

Examples	Radix tetrastigme	Herba Lysimachiae Christinae	Chrysanthemum morifolium Ramat	Licorice root, radix Glycyrrhizae
					Example 1	5	1.8	1.8	1.4
Example 2	7.5	2.0	2.0	1.5
					Example 3	10	2.2	2.2	1.6

The use method of the oral anti-inflammatory tea matched with the traditional Chinese medicine external ointment patch provided by the embodiment 1 comprises the following steps:

step A, weighing the following raw materials in parts by weight:

5 parts of radix tetrastigme, 1.8 parts of desmodium, 1.8 parts of wild chrysanthemum and 1.4 parts of liquorice;

step B, soaking the raw materials in the step A for 5min by 500 parts of water with the temperature of 98 ℃ to obtain tea soup, and drinking the tea soup;

and C, repeating the step B1 times every 4h for 7 times.

Examples 2-3 provide oral anti-inflammatory teas using the same method as example 1, except that:

in example 2, step B was repeated every 5h, 5 times;

in example 3, step B was repeated every 5h, 3 times.

Several real cases will now be provided to illustrate the advantageous effects of the embodiments of the present invention.

Patients 1, male, 45 years old and appendicitis are cured after 2 treatment courses by using the traditional Chinese medicine external ointment paste provided by the embodiment of the invention, and no operation or oral antibiotic treatment is performed in the period.

Patients 2, 7 years old and 7 years old have acute appendicitis attack in morning and have hard pain, the traditional Chinese medicine external ointment paste provided by the embodiment of the invention is used, the anti-inflammatory tea provided by the embodiment of the invention is taken at the same time, the pain feeling is obviously relieved in afternoon in the same day, the ointment paste is continuously used for a half treatment course, the anti-inflammatory tea is taken in the same period, and then the ointment paste is sent to a hospital for disease-free examination.

Patients 3, male, 40 years old and lung cancer, who want to give up at a time because they cannot bear the pain and economic pressure caused by frequent chemotherapy and radiotherapy, use the traditional Chinese medicine external ointment patch provided by the embodiment of the invention for 10 courses of treatment later, and the combined dose is lower than that of the previous chemotherapy and radiotherapy, so that the existing condition is gradually stable and has obvious signs of improvement.

The above specific embodiments may be combined with each other, and details of the same or similar concepts or processes may not be repeated in some embodiments.

All the technical features of the above embodiments can be combined arbitrarily, and for simplicity of description, all possible combinations of the technical features of the above embodiments are not described; these examples, which are not explicitly described, should be considered to be within the scope of the present description.

The present invention has been described in considerable detail by the general description and the specific examples given above. It should be noted that it is obvious that several variations and modifications can be made to these specific embodiments without departing from the inventive concept, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.