阅读说明：本技术 可用于合成软海绵素大环内酯及其类似物的普林斯反应和化合物 (Prins reaction and compounds useful for the synthesis of halichondrin macrolides and analogs thereof ) 是由 H-W·蔡 F·G·方 于 2019-01-03 设计创作，主要内容包括：本发明提供了利用普林斯反应制备化合物的方法,所述化合物可以用作合成软海绵素大环内酯及其类似物的中间体。本发明还提供了可以用作合成软海绵素大环内酯的中间体的化合物及其制备方法。(The present invention provides a process for preparing compounds useful as intermediates in the synthesis of halichondrin macrolides and analogs thereof using the prins reaction. The invention also provides compounds useful as intermediates in the synthesis of halichondrin macrolides and methods for their preparation.)