诱导调节性t细胞的增殖或积累的组合物
阅读说明:本技术 诱导调节性t细胞的增殖或积累的组合物 (Composition for inducing proliferation or accumulation of regulatory T cells ) 是由 本田贤也 新幸二 伊藤喜久治 田上大 于 2011-06-03 设计创作,主要内容包括:本发明涉及诱导调节性T细胞的增殖或积累的组合物。本发明人发现属于梭菌属的细菌在结肠中诱导调节性T细胞(Treg细胞)的积累。此外,本发明人发现由这些细菌诱导的调节性T细胞(Treg细胞)阻遏效应T细胞的增殖。根据这些发现,本发明人发现利用属于梭菌属的细菌或由其获得的生理活性物质使得可能诱导调节性T细胞(Treg细胞)的增殖或积累,并进一步阻遏免疫功能。(The present invention relates to compositions that induce proliferation or accumulation of regulatory T cells. The present inventors found that bacteria belonging to the genus clostridium induce accumulation of regulatory T cells (Treg cells) in the colon. Furthermore, the inventors found that regulatory T cells (Treg cells) induced by these bacteria suppress the proliferation of effector T cells. Based on these findings, the present inventors found that the use of bacteria belonging to the genus Clostridium or physiologically active substances obtained therefrom makes it possible to induce proliferation or accumulation of regulatory T cells (Treg cells) and further suppress immune function.)