阅读说明：本技术 一种抑制病原微生物繁殖的防护口罩的制备工艺及其制品 (Preparation process of protective mask for inhibiting propagation of pathogenic microorganisms and product thereof ) 是由 刘达治 于 2020-05-28 设计创作，主要内容包括：本发明公开了一种抑制病原微生物繁殖的防护口罩的制备工艺,通过二甲基十八烷基[3-(三羟基硅烷基)丙基]氯化铵的使用结合特定的工艺参数,在口罩上形成稳固的涂层,可以实现口罩在接触到空气中颗粒物所携带的病原微生物时直接抑制其活性,避免其在口罩表面繁殖,解决因佩戴过程造成的手污染和使用后丢弃时带来的废弃物生物污染。该技术有别于使用银离子或铜离子等技术,无游离,不会透过皮肤屏障,无皮肤刺激性。(The invention discloses a preparation process of a protective mask for inhibiting propagation of pathogenic microorganisms, which is characterized in that a firm coating is formed on the mask by combining the use of dimethyl octadecyl [3- (trihydroxy silyl) propyl ] ammonium chloride with specific process parameters, so that the mask can directly inhibit the activity of the pathogenic microorganisms carried by particles in the air when contacting the pathogenic microorganisms, the propagation of the pathogenic microorganisms on the surface of the mask is avoided, and the hand pollution caused by the wearing process and the biological pollution of wastes caused by discarding after use are solved. The technology is different from the technology using silver ions or copper ions and the like, has no dissociation, cannot penetrate through skin barriers, and has no skin irritation.)

1. A preparation process of a protective mask for inhibiting the propagation of pathogenic microorganisms is characterized by comprising the following steps: and (3) finishing dimethyl octadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride on the surface of the non-woven fabric, and drying the non-woven fabric to prepare the mask.

2. The process for preparing a protective mask capable of inhibiting pathogenic microorganisms from propagating according to claim 1, wherein the finishing method is one selected from padding, soaking and spraying.

3. The process for preparing a protective mask capable of inhibiting pathogenic microorganisms from propagating according to claim 1, wherein the non-woven fabric is made of one material selected from PP, PET and PA.

4. The process for preparing a protective mask capable of inhibiting pathogenic microorganism propagation according to claim 1, wherein the amount of the dimethyloctadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride is 3 to 5 wt% of the nonwoven fabric.

5. The process for preparing a protective mask capable of inhibiting the propagation of pathogenic microorganisms according to claim 1, wherein the temperature of the non-woven fabric is maintained at 40-60 ℃.

6. The process for preparing a protective mask capable of inhibiting pathogenic microorganism propagation according to claim 1, wherein the pH value of the non-woven fabric in the preparation process is not more than 6.

7. The process for preparing a protective mask capable of inhibiting pathogenic microorganisms from propagating according to claim 4, wherein the pH value is adjusted by using citric acid or acetic acid.

8. The process for preparing a protective mask capable of inhibiting pathogenic microorganism propagation according to any one of claims 1 to 7, wherein the finishing time is 10 to 30 min.

9. A protective mask for inhibiting the propagation of pathogenic microorganisms, which is prepared by the preparation process according to any one of claims 1 to 8.

10. The respirator for inhibiting the propagation of pathogenic microorganisms as claimed in claim 9, wherein the sterilization rate of the respirator to staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, pseudomonas pneumoniae and candida albicans is greater than 99.9% according to the AATCC 100-.

Technical Field

The invention relates to the field of protective articles, in particular to a preparation process of a protective mask for inhibiting the propagation of pathogenic microorganisms and a product thereof.

Background

The mask is a sanitary article, is worn at the mouth and nose part and is used for filtering air entering the mouth and nose so as to achieve the effect of blocking harmful gas, smell, spray, virus and other substances, and under the condition of epidemic prevention and control normalization, the protective mask becomes an essential daily article for people to work and live.

In practical application, the antibacterial performance and the filtering performance of the protective mask are put in the first place, when the filtering performance is continuously improved, pathogenic microorganisms can be attached to the outside of the mask, and the microorganisms can be continuously propagated, so that the treatment of mask wastes becomes a difficult problem, and the contact pollution of hands can be caused in the wearing process. At present, antibacterial metal ions such as silver ions and copper ions are added into protective masks on the market, all belong to heavy metals, and can possibly penetrate through skin barriers to cause stimulation to the skin; some mask products can adopt an antibacterial coating technology to realize an antibacterial effect, however, the coatings have poor stability and poor antibacterial effect under outdoor strong illumination.

Disclosure of Invention

In order to solve the above problems, a first aspect of the present invention provides a process for preparing a protective mask for inhibiting the propagation of pathogenic microorganisms, comprising the steps of: and (3) finishing dimethyl octadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride on the surface of the non-woven fabric, and drying the non-woven fabric to prepare the mask.

As a preferable technical scheme, the finishing method is selected from one of padding, soaking and spraying.

As a preferable technical solution, the material of the non-woven fabric is selected from one of PP, PET and PA.

As a preferable technical scheme, the dosage of the dimethyl octadecyl [3- (trihydroxy silyl) propyl ] ammonium chloride is 3-5 wt% of the non-woven fabric.

As a preferable technical scheme, the temperature of the non-woven fabric in the preparation process is kept at 40-60 ℃.

As a preferable technical scheme, the pH value of the non-woven fabric in the preparation process is not more than 6.

As a preferred technical scheme, the pH value is adjusted by using citric acid or acetic acid.

As a preferable technical scheme, the finishing time is 10-30 min.

The second aspect of the present invention provides a protective mask for inhibiting the propagation of pathogenic microorganisms, which is prepared by the preparation process as described above.

As a preferable technical scheme, according to the test of AATCC 100-.

Has the advantages that: the invention provides a preparation process of a protective mask for inhibiting propagation of pathogenic microorganisms, wherein a firm coating is formed on the mask by combining the use of dimethyl octadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride with specific process parameters, so that the mask can directly inhibit the activity of the pathogenic microorganisms carried by particles in the air when contacting the pathogenic microorganisms, the propagation of the pathogenic microorganisms on the surface of the mask is avoided, and the problems of hand pollution caused by the wearing process and waste biological pollution caused by discarding after use are solved. The technology is different from the technology using silver ions or copper ions and the like, has no dissociation, cannot penetrate through skin barriers, and has no skin irritation.

Drawings

In order to further explain the beneficial effects of the manufacturing process of the protective mask for inhibiting the propagation of pathogenic microorganisms and the product thereof, provided by the invention, the corresponding drawings are provided, and it should be noted that the drawings provided by the invention are only selected from individual examples in all drawings and are not intended to limit the claims, and all other corresponding maps obtained through the drawings provided by the application should be considered to be within the protection scope of the application.

FIG. 1 shows the results of the antibacterial property test of example 1 of the present invention.

FIG. 2 is a photograph of a Staphylococcus aureus test.

FIG. 3 is a photograph of a test for Klebsiella pneumoniae.

FIG. 4 shows the results of skin irritation experiments with dimethyloctadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride.

FIG. 5 shows the results of the filtration efficiency and airflow resistance tests of example 1 of the present invention.

Fig. 6 is an article of the present invention.

Detailed Description

The invention will be further understood by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. To the extent that a definition of a particular term disclosed in the prior art is inconsistent with any definitions provided herein, the definition of the term provided herein controls.

As used herein, a feature that does not define a singular or plural form is also intended to include a plural form of the feature unless the context clearly indicates otherwise. It will be further understood that the term "prepared from …," as used herein, is synonymous with "comprising," including, "comprising," "having," "including," and/or "containing," when used in this specification means that the recited composition, step, method, article, or device is present, but does not preclude the presence or addition of one or more other compositions, steps, methods, articles, or devices. Furthermore, the use of "preferred," "preferably," "more preferred," etc., when describing embodiments of the present application, is meant to refer to embodiments of the invention that may provide certain benefits, under certain circumstances. However, other embodiments may be preferred, under the same or other circumstances. In addition, the recitation of one or more preferred embodiments does not imply that other embodiments are not useful, nor is it intended to exclude other embodiments from the scope of the invention.

In order to solve the above problems, a first aspect of the present invention provides a process for preparing a protective mask for inhibiting the propagation of pathogenic microorganisms, comprising the steps of: and (3) finishing dimethyl octadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride on the surface of the non-woven fabric, and drying the non-woven fabric to prepare the mask.

Dimethyl octadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride (CAS number: 199111-50-7) as a quaternary ammonium salt can be combined with pathogenic microorganisms through the acting forces of electrostatic force, hydrogen bond force and the like to play a role in sterilization, has higher reaction activity compared with alkoxy organosilicon compounds, can be used for efficiently finishing non-woven fabrics, and simultaneously, because of the high activity, the processing conditions of the finishing process are severer.

Dimethyloctadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride in this application was purchased from Syngnan chemical (Shanghai) Co., Ltd.

In some preferred embodiments, the method of finishing is selected from one of padding, soaking, spraying.

Dimethyloctadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride is usually diluted with water by a factor of 10 to 30 when used. The method comprises the following steps of dispersing dimethyl octadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride in water, immersing non-woven fabric in the water, or padding or spraying aqueous solution of dimethyl octadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride on the non-woven fabric, wherein the compound has a positive electricity center, is attached to the surface of the non-woven fabric under the attraction of electrostatic force, is subjected to intermolecular dehydration condensation, forms a film on the surface of the non-woven fabric, and long-chain alkyl can penetrate into fibers to enhance the binding force between the film and the non-woven fabric.

In some preferred embodiments, the material of the non-woven fabric is selected from one of PP, PET, PA. Materials such as PP (polypropylene), PET (polyester), PA (nylon) and the like have excellent chemical resistance, so that the finishing effect of a common finishing agent is poor, the function is difficult to maintain for a long time, and the dimethyl octadecyl [3- (trihydroxy silyl) propyl ] ammonium chloride has a special structure and can be stably combined with the materials such as PP, PET, PA and the like under the condition of matching with a specific process.

From the viewpoint of enhancing the antimicrobial effect and reducing the waste of raw materials, in some preferred embodiments, the dimethyloctadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride is used in an amount of 3 to 5 wt% based on the nonwoven fabric. The inventors have found that dimethyloctadecyl [3- (trihydroxysilyl) propyl ] ammonium chloride can stably attach the antibacterial groups to the surface fibers of the substrate by forming covalent bonds, and thus the number of the bonding sites is also relative, and the antibacterial activity is best exhibited when saturated. When the amount of the compound is too small, the bactericidal activity cannot be achieved, however, when the amount exceeds the preferable range, the compound is not bonded to the surface layer of the substrate more, and thus the excessive amount becomes ineffective.

In some preferred embodiments, the temperature of the non-woven fabric in the preparation process is kept between 40 ℃ and 60 ℃ from the viewpoint of improving the bacteriostatic effect of the non-woven fabric and the efficiency of the preparation process; further preferably, the temperature of the non-woven fabric in the preparation process is kept at 40-55 ℃. The inventor finds that the silicon hydroxyl and the fiber surface can be bonded, the bonding force of the compound and the non-woven fabric is further improved, the compound can be more quickly bonded with the substrate within a preferable reaction temperature range, the reaction speed of the compound is reduced when the temperature is reduced, but the activity of the compound is obviously improved when the temperature is too high, and the compound which is free in water is subjected to dehydration condensation, so that the number of the compound attached to the surface of the non-woven fabric is greatly reduced, and a complete covering film is difficult to form. In the case of the compound amount of 5 wt%, the temperature may be suitably lowered but not lower than 40 ℃.

In some preferred embodiments, the pH value of the non-woven fabric in the preparation process is not more than 6, from the viewpoint of improving the antibacterial effect, the lasting effect and the wearing comfort of the mask; more preferably, the pH value of the non-woven fabric is 4-5. The inventor finds that the bonding force between the compound and the surface of the non-woven fabric is good and the antibacterial effect is excellent under the condition that the surface of the non-woven fabric is in a weakly acidic environment, the compound can be promoted to be dehydrated and condensed to form a coating film by a certain acidity, but the condensation reaction is accelerated when the compound exceeds a preferable range, the compound which is not timely attached to the surface of the non-woven fabric is also greatly condensed, the bonding quantity between the compound and the surface layer molecules of the matrix is reduced, and the antibacterial effect is greatly reduced. In addition, the alkaline condition also contributes to the improvement of the reactivity of the compound, but because the surface of human skin is weakly acidic, the alkaline mask surface can stimulate the skin, and the wearing comfort is affected.

The method for measuring the pH value of the nonwoven fabric in the present application may be any one known to those skilled in the art, for example, the method described in GB/T7573-2009 determination of pH value of aqueous textile extract.

In some preferred embodiments, the pH is adjusted using citric acid or acetic acid.

In some preferred embodiments, the finishing time is 10 to 30min from the viewpoint of improving the protective effect and the production efficiency of the mask. The inventor finds that the materials of the non-woven fabric are usually very good in chemical stability, and conventional auxiliary agents are difficult to react with the non-woven fabric, so that the chemical compounds can be contacted with the surface layer molecules of the fibers for a certain time at a certain temperature to ensure that the chemical compounds can establish stable covalent bonds with the surface layer molecules of the fibers, and meanwhile, the sufficient amount of the chemical compounds is ensured.

The inventors have unexpectedly found that the protective mask prepared by the above preparation process has excellent ultraviolet resistance and antistatic performance because the above preparation process enables a coating structure formed by the compound to have high crosslinking density and strong bonding force with non-woven fabrics, chemical bonds in the coating structure can bear high-energy ultraviolet rays without fracture, the continuity of the formed film is strong, and positive centers are close to each other, so that the coating has certain conductivity, and the antistatic performance is improved.

The second aspect of the present invention provides a protective mask for inhibiting the propagation of pathogenic microorganisms, which is prepared by the preparation process as described above.

According to the test of AATCC 100-.