阅读说明：本技术 用于在疾病的预防和/或治疗中使用的疫苗 (Vaccine for use in the prevention and/or treatment of disease ) 是由 P.霍尔斯特 C.蒂里翁 L.诺伊基尔希 于 2018-08-30 设计创作，主要内容包括：本发明涉及能够编码病毒样颗粒(VLP)的腺病毒载体,所述VLP展示无活性的免疫抑制结构域(ISD)。本发明的疫苗显示来自由CD4T细胞或CD8T细胞起始的两种应答途径中任一者的改善的免疫应答。(The present invention relates to adenoviral vectors capable of encoding virus-like particles (VLPs) displaying an inactive immunosuppressive domain (ISD). The vaccines of the present invention show improved immune responses from either of two response pathways initiated by CD4T cells or CD8T cells.)