阅读说明：本技术 改善儿童睡眠障碍的奶粉及其制备方法 (Milk powder for improving sleep disorder of children and preparation method thereof ) 是由 薛玉玲 王世杰 朱宏 冯丽莉 荀一萍 张栋 贾晓江 封肖颖 于 2020-05-22 设计创作，主要内容包括：本发明属于食品领域,具体公开了一种改善儿童睡眠障碍的奶粉及其制备方法,由生牛乳、乳清蛋白粉、浓缩乳清蛋白粉、乳糖、1,3-二油酸-2-棕榈酸甘油三酯粉、脱盐乳清粉、大豆油、低聚半乳糖、低聚果糖、磷脂份、碳酸钙、花生四烯酸粉剂、鱼油粉、氯化胆碱、复合维生素、复合矿物质、营养补充粉剂、复合菌粉Ⅰ、复合菌粉Ⅱ、水等原料,经生牛乳验收、净乳、预巴杀、混合调配、杀菌、闪蒸、过滤、浓缩、喷雾干燥、冷却、干混等步骤制备。本发明提供的奶粉为儿童提供丰富的营养物质的同时,达到了改善儿童睡眠障碍,促进睡眠的效果；本发明提供的制备方法易于控制。本发明的制备方法适用于制备改善儿童睡眠障碍的奶粉,所制奶粉适用于儿童。(The invention belongs to the field of food, and particularly discloses milk powder for improving sleep disorder of children and a preparation method thereof. The milk powder provided by the invention provides abundant nutrient substances for children, and achieves the effects of improving the sleep disorder of the children and promoting the sleep; the preparation method provided by the invention is easy to control. The preparation method is suitable for preparing the milk powder for improving the sleep disorder of children, and the prepared milk powder is suitable for children.)

1. The milk powder for improving the sleep disorder of children is characterized in that raw materials for preparing active ingredients of the milk powder comprise, by weight, 250-350 parts of raw milk, 32.5-42.5 parts of whey protein powder, 36-42 parts of concentrated whey protein powder, 12.5-15.5 parts of lactose, 7.5-10.5 parts of 1, 3-dioleate-2-palmitic triglyceride powder, 20-28 parts of desalted whey powder, 4-6 parts of soybean oil, 2.5-4 parts of galactose oligomer, 1.2-2.4 parts of fructo-oligosaccharide, 0.6-0.9 part of phospholipid, 0.4-0.7 part of calcium carbonate, 0.3-0.6 part of arachidonic acid powder, 0.22-0.4 part of fish oil powder, 0.17-0.25 part of choline chloride, 0.25-0.3 part of compound vitamin, 0.15-0.2 part of compound mineral substance supplementing powder, 7.21-8.7 parts of nutrient powder, 0.05-0.05 part of compound bacteria powder I, 0.2-0.2 part of bacteria powder and 3-20 parts of compound water;

wherein, the raw materials for preparing the effective components of the nutrition supplementing powder comprise the following components in percentage by weight of 1: 2: 2: 1: 0.5 of corn flour, millet flour, chickpea flour, oat flour and litchi flour;

the raw materials for preparing the effective components of the composite bacterial powder I comprise the following components in percentage by weight: 2: 1 lactobacillus paracasei N1115, lactobacillus plantarum, lactobacillus acidophilus;

the raw materials for preparing the effective components of the compound bacterial powder II comprise the following components in percentage by weight: 2: 1: 1 lactobacillus paracasei N1115, bifidobacterium animalis, lactobacillus acidophilus and lactobacillus rhamnosus.

2. The milk powder for improving sleep disorder of children as claimed in claim 1, wherein the content of probiotics in the composite bacteria powder I is 1 × 10¹²～1.5×10¹²The content of the probiotics in the compound bacteria powder II is 1 × 10¹²～1.5×10¹²CFU/kg。

3. The milk powder for improving sleep disorder of children according to claim 1 or 2, wherein the raw materials for preparing the active ingredients of the multivitamin comprise, by weight, 1: 40: 8: 0.01: 30 of vitamin a, vitamin D, vitamin E, vitamin C and B vitamins.

4. The milk powder for improving sleep disorder of children according to claim 1 or 2, wherein the raw materials for preparing the composite mineral active ingredients comprise, by weight, 5: 1 magnesium and iron.

5. The milk powder for improving sleep disorder of children as claimed in claim 3, wherein the raw materials for preparing the composite mineral active ingredients comprise the following components in weight ratio of 5: 1 magnesium and iron.

6. A method for preparing milk powder for improving sleep disorder of children as claimed in any one of claims 1 to 5, wherein the method comprises the following steps:

first, checking and accepting raw milk, purifying milk and pre-pasteurizing

Standardizing raw milk, separating impurities, pasteurizing, and cooling to obtain product A;

mixing and blending

(a) Dissolving the nutrition supplementing powder and the compound bacterium powder I in water, and standing at a maintained temperature to obtain a product B;

(b) dissolving the compound vitamin and choline chloride in water to obtain a product C;

(c) dissolving the composite mineral substance and calcium carbonate in water to obtain a product D;

(d) mixing whey protein powder, desalted whey powder, lactose, concentrated whey protein powder, phospholipid, soybean oil, galacto-oligosaccharide, fructo-oligosaccharide, product B, product C and product D, homogenizing and cooling to obtain product E;

thirdly, sterilizing, flash evaporating, filtering and concentrating

Mixing the product A and the product E, and then sterilizing, flashing, filtering and concentrating to obtain a product F;

spray drying and cooling

Spray-drying the product F, and cooling to obtain a product G;

mixing by a dry method

And (3) mixing the product G with 1, 3-dioleoyl-2-palmitic acid triglyceride powder, arachidonic acid powder, fish oil powder and compound bacteria powder II by a dry method to obtain the milk powder for improving the sleep disorder of children.

7. The method according to claim 6, wherein the pasteurization temperature in the first step is 53-58 ℃ and the temperature reduction temperature is 0-6 ℃.

8. The preparation method according to claim 6 or 7, wherein the dissolving temperature in the second step (a) is 37-42 ℃, and the standing time is 2-4 h; the dissolving temperature in the second step (b) is 33-37 ℃; in the second step (c), the dissolving temperature is 48-52 ℃; and (d) in the homogenization in the step two (d), the first-stage homogenization pressure is 80-120 bar, the second-stage homogenization pressure is 25-35 bar, the third-stage homogenization pressure is 170-210 bar, and the cooling temperature is 4-8 ℃.

9. The preparation method according to claim 8, wherein the mixture obtained in the third step is stirred for 20-30 min, sterilized at 94-96 ℃ for 5s, flash evaporated by a flash evaporator, filtered by a duplex filter with a diameter of 500 μm, and evaporated and concentrated by a triple-effect falling film evaporator.

10. The preparation method according to any one of claims 6, 7 and 9, wherein in the spray drying in the fourth step, the spray pressure is 170-240 bar, the inlet air temperature is 150-170 ℃, the exhaust air temperature is 85-90 ℃, the pressure in the drying chamber is-110 to-90 Pa, and the cooling temperature is less than 30 ℃.

Technical Field

The invention belongs to the field of food, and relates to milk powder, in particular to milk powder for improving sleep disorder of children and a preparation method thereof.

Background

Sleep disorder is a common clinical disease, and is the manifestation of abnormal sleep quality and abnormal behavior in sleep, and the manifestation of alternating disorder of normal rhythmicity of sleep and wakefulness. Investigation shows that many people suffer from sleep disorders or sleep-related diseases, the proportion of sleep disorders of adults is up to 30%, and about 30% -45% of children and teenagers in China also suffer from sleep disorders of different degrees, and the sleep disorders have high morbidity and are clinically manifested by the problems of difficulty in falling asleep, poor sleep quality and the like.

The sleep plays an important role in the growth and development process of children, and the sleep disorder not only can influence the growth and development of children, but also can cause serious negative effects on immunity, intelligence development, psychology and behaviors. Therefore, sleeping plays an important role in physical and mental health of children.

For children, the special population, the use of drugs to improve sleep disorder is not desirable, and general hypnotic drugs can act on the nervous system to influence the growth and development of children. Therefore, the method is a safe and effective way for improving the sleep quality of children through the regulation of nutrient elements and active substances.

Disclosure of Invention

The invention aims at children and provides milk powder for improving sleep disorder of children, so that the milk powder can comprehensively supplement nutrition for the children and simultaneously improve the sleep disorder of the children; another object of the present invention is to provide a method for preparing the milk powder for improving sleep disorders of children.

In order to achieve the purpose, the invention adopts the following technical scheme:

the milk powder for improving the sleep disorder of children comprises, by weight, 250-350 parts of raw milk, 32.5-42.5 parts of whey protein powder, 36-42 parts of concentrated whey protein powder, 12.5-15.5 parts of lactose, 7.5-10.5 parts of 1, 3-dioleate-2-palmitic acid triglyceride powder, 20-28 parts of desalted whey powder, 4-6 parts of soybean oil, 2.5-4 parts of galacto-oligosaccharide, 1.2-2.4 parts of fructo-oligosaccharide, 0.6-0.9 part of phospholipid, 0.4-0.7 part of calcium carbonate, 0.3-0.6 part of arachidonic acid powder, 0.22-0.4 part of fish oil powder, 0.17-0.25 part of choline chloride, 0.25-0.3 part of compound vitamin, 0.15-0.2 part of compound mineral substance, 7.21-8.7 parts of nutrition supplementing powder, 0.05-0.05 part of compound bacteria powder, 0.1.2-0.2 part of compound bacteria powder and 3-20 parts of water;

wherein, the raw materials for preparing the effective components of the nutrition supplementing powder comprise the following components in percentage by weight of 1: 2: 2: 1: 0.5 of corn flour, millet flour, chickpea flour, oat flour and litchi flour;

the raw materials for preparing the effective components of the composite bacterial powder I comprise the following components in percentage by weight: 2: 1 lactobacillus paracasei N1115, lactobacillus plantarum, lactobacillus acidophilus;

the raw materials for preparing the effective components of the compound bacterial powder II comprise the following components in percentage by weight: 2: 1: 1 lactobacillus paracasei N1115, bifidobacterium animalis, lactobacillus acidophilus and lactobacillus rhamnosus.

The content of probiotics in the composite bacteria powder I is 1 × 10 as a limit¹²～1.5×10¹²The content of the probiotics in the compound bacteria powder II is 1 × 10¹²～1.5×10¹²CFU/kg。

As a further limitation: the raw materials for preparing the active ingredients of the compound vitamin comprise the following components in percentage by weight: 40: 8: 0.01: 30 of vitamin a, vitamin D, vitamin E, vitamin C and B vitamins.

As a further limitation: the raw materials for preparing the effective components of the compound minerals comprise the following components in percentage by weight: 1 magnesium and iron.

The invention also provides a preparation method of the milk powder for improving the sleep disorder of children, which comprises the following steps:

first, checking and accepting raw milk, purifying milk and pre-pasteurizing

Standardizing raw milk, separating impurities, pasteurizing, and cooling to obtain product A;

mixing and blending

(a) Dissolving the nutrition supplementing powder and the compound bacterium powder I in water, and standing at a maintained temperature to obtain a product B;

(b) dissolving the compound vitamin and choline chloride in water to obtain a product C;

(c) dissolving the composite mineral substance and calcium carbonate in water to obtain a product D;

(d) mixing whey protein powder, desalted whey powder, lactose, concentrated whey protein powder, phospholipid, soybean oil, galacto-oligosaccharide, fructo-oligosaccharide, product B, product C and product D, homogenizing and cooling to obtain product E;

thirdly, sterilizing, flash evaporating, filtering and concentrating

Mixing the product A and the product E, and then sterilizing, flashing, filtering and concentrating to obtain a product F;

spray drying and cooling

Spray-drying the product F, and cooling to obtain a product G;

mixing by a dry method

And (3) mixing the product G with 1, 3-dioleoyl-2-palmitic acid triglyceride powder, arachidonic acid powder, fish oil powder and compound bacteria powder II by a dry method to obtain the milk powder for improving the sleep disorder of children.

As a limitation: in the first step, the pasteurization temperature is 53-58 ℃, and the cooling temperature is 0-6 ℃.

As a further limitation: in the second step (a), the dissolving temperature is 37-42 ℃, and the standing time is 2-4 h; the dissolving temperature in the second step (b) is 33-37 ℃; in the second step (c), the dissolving temperature is 48-52 ℃; and (d) in the homogenization in the step two (d), the first-stage homogenization pressure is 80-120 bar, the second-stage homogenization pressure is 25-35 bar, the third-stage homogenization pressure is 170-210 bar, and the cooling temperature is 4-8 ℃.

As yet a further limitation: mixing in the third step, stirring for 20-30 min, sterilizing at 94-96 deg.C for 5s, flash evaporating, filtering with 500 μm duplex filter, and evaporating and concentrating with triple-effect falling-film evaporator.

As a further limitation: in the spray drying of the fourth step, the spray pressure is 170-240 bar, the air inlet temperature is 150-170 ℃, the air exhaust temperature is 85-90 ℃, the pressure in the drying chamber is-110-90 Pa, and the cooling temperature is less than 30 ℃.

Due to the adoption of the scheme, compared with the prior art, the invention has the beneficial effects that:

(1) alpha-lactalbumin is the protein with the highest tryptophan content in food protein, the increase of tryptophan can induce the synthesis of 5-hydroxytryptamine, and the 5-hydroxytryptamine participates in the generation and maintenance of sleep. The milk powder for improving the sleep disorder of children improves the content of alpha-lactalbumin in the milk powder by reasonably proportioning the raw milk, the whey protein powder, the concentrated whey protein powder and the desalted whey powder, thereby improving the content of 5-hydroxytryptamine, promoting the adjustment of the sleep function and improving the sleep quality;

(2) the gamma-aminobutyric acid can inhibit nerve center, has effects of improving sleep and tranquilizing, and has no side effects. The milk powder for improving the sleep disorder of children provided by the invention produces gamma-aminobutyric acid by fermenting litchi with lactobacillus paracasei N1115, lactobacillus plantarum and lactobacillus acidophilus, and simultaneously, glucose, protein and sodium glutamate provided by corn flour, millet flour, chickpea flour and oat flour further improve the amount of gamma-aminobutyric acid produced by fermenting strains;

(3) the B vitamins have certain sleep regulating effect. The milk powder for improving the sleep disorder of children promotes intestinal flora to generate B vitamins by the cooperation of lactobacillus paracasei N1115, bifidobacterium animalis, lactobacillus acidophilus, lactobacillus rhamnosus, galacto-oligosaccharide and fructo-oligosaccharide, so that the sleep is promoted to be recovered to be normal;

(4) the compound vitamins in the milk powder for improving the sleep disorder of children provided by the invention contain vitamin D, vitamin E, vitamin C and vitamin B related to sleep, and the effects of regulating sleep and improving sleep quality are achieved through reasonable proportioning;

(5) corn contains abundant magnesium and B vitamins, millet contains abundant tryptophan and vitamins, and chickpea contains vitamin B₆The oat contains natural sleep-aiding nutrient elements such as N-acetyl-5-methoxytryptamine and the like. The milk powder for improving the sleep disorder of children improves the sleep-aiding effect of the milk powder and also provides more abundant nutrient substances for children by reasonably proportioning the corn flour, the millet flour, the chickpea flour and the oat flour;

(6) calcium and magnesium regulate the contraction and relaxation of muscles, while calcium, together with tryptophan, produces melatonin, which contributes to sleep, and in addition, iron deficiency in children, also produces symptoms of fatigue and sleep disorders. The milk powder for improving the sleep disorder of children provided by the invention has the advantages that the calcium, the magnesium and the iron are reasonably added, so that the maximum functional effect is exerted on the basis of ensuring the required amount of children, and the sleep of the children is promoted;

(7) the preparation method provided by the invention comprises the steps of raw milk acceptance, milk purification, pre-pasteurization, mixing and blending, sterilization, flash evaporation, filtration, concentration, spray drying, cooling, dry mixing and the like, and the process is easy to control;

in conclusion, the milk powder provided by the invention provides abundant nutrient substances for children, and achieves the effects of improving the sleep disorder of the children and promoting the sleep; the preparation method provided by the invention is easy to control.

The preparation method is suitable for preparing the milk powder for improving the sleep disorder of children, and the prepared milk powder for improving the sleep disorder of children is suitable for children.

Detailed Description

The present invention is further described with reference to the following examples, but it should be understood by those skilled in the art that the present invention is not limited to the following examples, and any modifications and variations based on the specific examples of the present invention are within the scope of the claims of the present invention.