阅读说明：本技术 一种制备藏药成分锡灰的方法 (Method for preparing Tibetan medicine component tin ash ) 是由 多吉当智 马文俊 陈海莲 刘有菊 胡燕芹 于 2020-04-16 设计创作，主要内容包括：本发明公开一种制备藏药成分锡灰的方法,该方法包括以下步骤：将锡薄片、诃子粉、毛诃子粉、余甘子粉在水中微火煮沸浓缩去毒,洗净,然后放入童子尿和沙棘汁中用微火煮沸煮沸去锈,将硼砂,硫磺和含核诃子粉液调和成糊状涂在铅锡片上,煅烧成灰,用清水清洗干净即得,该方法操作简单,制得的锡灰不但除去了毒性,还保持了作为藏药成分的药性。(The invention discloses a method for preparing Tibetan medicine component tin ash, which comprises the following steps: boiling tin slice, myrobalan powder, terminalia bellerica powder and emblic leafflower fruit powder in water with slow fire, concentrating, detoxifying, cleaning, then adding urine of boys and sea buckthorn juice, boiling with slow fire, removing rust, blending borax, sulfur and the liquid containing the myrobalan powder into paste, coating the paste on a lead-tin sheet, calcining into ash, and cleaning with clear water.)

1. A method for preparing tin ash of Tibetan medicine components comprises the following steps:

1) detoxification: placing 10g of tin sheet into a container, adding equivalent myrobalan powder, fructus terminaliae billericae powder and fructus phyllanthi powder, adding 200ml of water, boiling with slow fire, concentrating to about 50g, repeating the above process for 3 times, washing the residual tin sheet surface with clear water, and cleaning the stain on the tin sheet with clean gauze to remove the toxin;

2) derusting: putting the tin sheet obtained in the step 1) into a container, adding the boy urine and the sea buckthorn juice, boiling for 25-40 minutes by slow fire, washing with clear water, repeating the process for 4 times, and scrubbing stains on the tin sheet by using clean gauze to remove rust;

3) calcining auxiliary materials: weighing the tin sheets obtained in the step 2), weighing the same amount of borax and sulfur, blending the myrobalan powder with the core into paste with water, uniformly coating the paste on each tin sheet, wrapping the paste with gauze, and drying the paste;

4) and (3) calcining: putting the tin sheet obtained in the step 3) into a pottery jar for calcining, cooling and grinding to obtain tin ash;

5) cleaning: cleaning the tin ash obtained in the step 4) with hot water, drying, grinding and sieving to obtain the tin ash.

2. The method of claim 1, wherein in step 1), the weight ratio of tin to clear water is 1: 20.

3. the method according to claim 1, wherein in step 1), the weight ratio of tin to myrobalan powder, terminalia bellerica powder and emblic leafflower powder is 1:1:1: 1.

4. the method of claim 1, wherein in step 1) the boiling time with a slow fire is 30 minutes.

5. The method according to claim 1, wherein in the step 2), the weight volume ratio of tin to the boy urine and the sea buckthorn juice is 1g:50ml:50 ml.

6. The method of claim 1, wherein the slow fire boiling time of step 2) is 30 minutes.

7. The method of claim 1, wherein the tin flakes are tin flakes.

Technical Field

The invention belongs to the technical field of traditional Tibetan medicine national medicine, and particularly relates to a preparation method of metal tin ash of a Tibetan medicine component.

Background

Tibetan medicine is a wonderful medicine which attracts attention of the world on the magical land of Qinghai-Tibet plateau, and she bark on the top of the world in Indian medicine, western traditional medicine and traditional Chinese medicine. The Chinese important traditional national medicine has long history and unique curative effect, and plays a great role in maintaining the life health of Tibetan people to this day

However, with the development and popularization of Tibetan medicines, people pay more and more attention to the safety problem of Tibetan medicines while paying attention to the unique curative effect of Tibetan medicines, and particularly heavy metals contained in Tibetan medicines are the same as the current attention to the standard exceeding event of traditional Chinese medicine heavy metals, so that the problem to be solved urgently in the modernization process of traditional Chinese medicines is formed.

In the Tibetan medicine preparation, the twenty-five-ingredient coral pills, the twenty-five-ingredient pine stone pills, the renqing everlasting, the renqing and the mangoes and the like have the most traditional classic Tibetan medicines and are commonly used in Tibetan regions. And zolpidem is an important component of these classic Tibetan medicines. The Zote Tai is blue-black powder prepared from eight metals of gold, silver, red copper, bronze, brass, iron, lead and tin, and eight minerals of gold ore, silver ore, native copper, magnetite, aluminite, Orpimentum, Realgar and red mica by a special and complex process, is not used alone clinically, but is used as an additive component of Tibetan medicine preparations, and has the effects of promoting granulation, strengthening spleen, nourishing, strengthening, resisting diseases, building body, prolonging life and the like. Because the raw materials for refining the Zote comprise lead, arsenic-containing minerals of Orpimentum and Realgar, the Tibetan medicine preparation must contain heavy metals of lead and arsenic when being used as Zong, ren Qing Chang Zhi and seventy-flavor pearl pills. The targeted research is very important when the Tibetan medicine contains ingredients which cannot be explained at the present stage or are contrary to the understanding of modern science, such as high-content lead and arsenic. Lead and arsenic are internationally recognized toxic heavy metal elements (arsenic is a metalloid), acute toxicity is generated by a large amount of contact, long-term toxicity is generated by accumulation in a body by continuous contact, and strict control is required in the aspects of food, medicine, drinking water, environment and the like. The metal such as mercury, arsenic, silver, zinc, lead and the like has an inhibiting effect on the CYP450 enzyme activity, and the research results show that the moderate dose and the large dose of the zotaro have a remarkable inhibiting effect on the activities of CYP1A2 and NAT 2. According to literature reports, the analysis and evaluation of the heavy metal content of typical famous Tibetan medicines in the 18 th stage of volume 3 of 9 months in 2013 have the following analysis results: (1) ren Qing Chang Zhi: cellulose, carbonate (less); (2) seventy-ingredient pearl pills: carbonates, cellulose; (3) twenty five-ingredient pearl pills: carbonates, cellulose; (4) renqing mangoes: cellulose, carbonate. The analytical results were as follows: (1) the contents of Pb, Hg, As, Cu, Zn, Mn, Al, Ca, Fe, K, Mg, Na and P in the Renqueing normal feeling are higher; (2) the seventy-ingredient pearl pills have high Pb, Hg, As, Cu, Zn, Mn, Ba, Al, Ca, Fe, K, Mg, Na and P contents; (3) the twenty-five pearl pills have high Hg, Cu, Ba, Ca, Fe, K, Mg, Na and P contents; (4) in the ren Qing mango juice, the contents of Hg, Cu, Zn, Mn, Ba, Al, Ca, Fe, K, Mg, Na and P are higher. Generally, the contents of toxic and harmful heavy metals considered by modern health science in 4 precious Tibetan medicines such As Pb, Hg, As, Cu, Zn, Mn and the like are generally high, and the Tibetan medicines have certain health and safety risks after being taken for a long time; however, no obvious toxic effect caused by taking the Tibetan medicines is found in the real life, and the Tibetan medicine has unique curative effect on some diseases. The content of heavy metals in 4 Tibetan medicines is generally higher, especially the content of Pb, Hg, Cu and Zn in part of the Tibetan medicines is quite high. Sn is also one of the taizo 8 gold ashes. Therefore, traditional Tibetan medicines require detoxification treatment of these heavy metals. Such as the metal detoxification in the tezomib process, generally includes

1) The derusting process comprises placing the above three spice powders and hydrargyrum into a leather bag, tightening the bag, manually kneading, taking out after 3 days, cleaning with clear water, and adding sea buckthorn water overnight. Putting the hydrargyrum into stone tank, sequentially adding trona, green salt powder, triacid water, various salts, Natrii sulfas, Borax, Bulbus Allii water, and ghee, and stirring for about 21 days. Cleaning with clear water, and adding sea buckthorn water overnight.

2) The process of removing toxicity by a boiling method is carried out and the raw materials are boiled greatly; 3 kinds of calcite and triacid water are added into the above hydrargyrum, and the mixture is boiled in warm water in a stone pot for about 4 days. Intermediate cooking: the above mercury can be washed with water and boiled with water containing eight kinds of gold ashes and three kinds of acid water for about 2 days. Short cooking: cleaning the above mercury with water, adding radix Aconiti Kusnezoffii powder and Ciba Cinchonae ash, decocting, taking out mercury after about 1 day, and cleaning with water.

3) The mercury obtained by the method is placed in a stone tank to be added with prepared sulfur, and after the prepared sulfur is held in eight-color gold ash and the like, the mixture is fully stirred until the mercury particles are in a degree of mercury. Finally processing the mixture into a black powdery finished product 'Zote', which can float on the water surface without any sediment.

After the heavy metal is detoxified, the original toxic property of the heavy metal is basically lost, and the medicinal value is retained. Therefore, all the metal materials in the Tibetan medicine are not directly used as the medicine, but are processed into the powder by a special processing technology. The so-called "ash" is essentially metal-free in nature. The concept that the Tibetan medicine has high heavy metal content and many toxic medicinal materials is very wrong.

Although Tibetan medicine has a long history, the theoretical system is complete. However, for various reasons, the theory and practice system of Tibetan medicine is greatly damaged, mainly shown in the following aspects:

1. the traditional mode of 'transmission of ears and ears', 'transmission of apprentices and fathers and children' and the excellent 'Saita' processing skills are not known and applied by most people due to the limitation of regions and the closure of nationalities, and only exist in the national minority temple institute of Qinghai-Tibet plateau and Tibetan medicine production units. Therefore, it cannot be inherited completely, so that the processing technique of Tibetan medicine is endangered to be extinct. 2. The processing of the Tibetan medicines comprises the processing of plant medicines, animal medicines, mineral medicines, metal medicines and mineral medicines and the like. The gold processing process is more than 300, so that the common people are difficult to learn, and the young people are not so loved to learn, so that fewer people can master the process.

At present, in the traditional Tibetan medicine process, the detoxification treatment of heavy metals is complex, the study is difficult, and the potential risk of gazelle is existed on the safety of the Tibetan medicine. Therefore, it is necessary to improve and innovate the heavy metal detoxification process, develop a simple, more stable and suitable industrial production process, and ensure the safety and effectiveness of the Tibetan medicine.

Disclosure of Invention

The invention aims to provide a preparation method of Tibetan medicine metal tin ash, which can effectively remove the toxicity of Tibetan medicine component tin and simultaneously keep the property of the Tibetan medicine.

The invention relates to a method for preparing Tibetan medicine component tin ash, which comprises the following steps:

1) placing 10g of tin sheet into a container, adding equivalent myrobalan powder, fructus terminaliae billericae powder and fructus phyllanthi powder, adding 200ml of water, boiling with slow fire, concentrating to about 50g, repeating the above process for 3 times, washing the surface residue (such as fructus terminaliae billericae powder and other auxiliary materials) of the tin sheet with clear water, and cleaning the stain on the tin sheet with clean gauze to remove the toxin;

2) derusting, namely putting the tin sheet obtained in the step 1) into a container, adding 500ml of urina hominis and 500m L of a proper amount of sea buckthorn juice, boiling for 25-40 minutes by slow fire, preferably for 30 minutes, washing by using clear water, repeating the process for 4 times, and scrubbing stains on the tin sheet by using clean gauze to remove the rust;

3) calcining auxiliary materials: weighing the tin slices obtained in the step 2), weighing the same amount of borax and sulfur, blending the mixture into paste by using a myrobalan powder aqueous solution with a core, uniformly coating the paste on each tin slice, wrapping the paste by using gauze, and drying the paste;

4) and (3) calcining: putting the tin sheet obtained in the step 3) into a pottery jar for calcining, cooling and grinding to obtain tin ash;

5) cleaning: cleaning the tin ash obtained in the step 4) with hot water, drying, grinding and sieving to obtain the tin ash.

Preferably, in the method of the present invention, in step 1), the weight ratio of tin to clear water is 1: 20, the weight ratio of the tin to the myrobalan powder, the terminalia bellerica powder and the emblic leafflower powder is 1:1:1:1 respectively, and the mixture is boiled for 30 minutes by mild fire

Preferably, in the method of the present invention, in the step 2), the weight volume ratio of tin to urina hominis and sea buckthorn juice is 1g:50ml:50 ml.

In one embodiment, the invention provides a preparation method of tin ash of a Tibetan medicine component, which comprises the following steps:

1) detoxification: placing 10g of tin slices into a container, adding equivalent myrobalan powder, terminalia bellerica powder and emblic leafflower powder, adding 200ml of water, boiling and concentrating with slow fire to about 50g, boiling for 3 times by the same method, washing with clear water for multiple times, and cleaning stains on tin foil with clean gauze to remove toxins;

2) removing rust, namely putting the tin sheet obtained by the ① method into a container, adding 500ml of boy urine and 500ml of sea buckthorn juice, boiling for 30 minutes by slow fire, washing with clear water, boiling and scrubbing for 4 times by the same method, scrubbing stains on tin foil by clean gauze, and drying to remove rust;

3) calcining adjuvants, weighing the tin slices obtained by ② method, weighing equal amount of borax and sulfur, concocting with fructus Chebulae powder with core with water solution to obtain paste, uniformly coating on each tin slice, wrapping with gauze, and air drying;

4) calcining, namely calcining the tin sheet obtained by the ③ method in a special pottery jar, cooling, taking out and grinding to obtain the tin-based composite material;

5) cleaning, namely cleaning the tin ash obtained by the ④ method with hot water, drying, grinding, sieving and storing for later use.

The preparation method of the tin ash is simple, the quality is safe and easy to control, the quality is stable, the toxicity of tin is effectively removed, the property of the tin ash serving as a Tibetan medicine component is kept, and the effects of attenuation and synergism are achieved. Is suitable for industrial and commercial production.

Detailed Description

The following examples are merely representative for further illustration and understanding of the spirit of the present invention, and are not intended to limit the scope of the present invention, which is intended to cover any simple changes or modifications within the scope of the present invention.