阅读说明：本技术 一种葛根配方颗粒的制备方法 (Preparation method of radix puerariae formula granules ) 是由 方元平 周佑成 于 2018-09-10 设计创作，主要内容包括：本发明公开了一种制备葛根配方颗粒的方法,包括以下配方：葛根片100-200份、淀粉10-30份、蔗糖5-25份、糊精5-20份、乳糖20-50份。包括以下过程：将葛根饮片加质量6～15倍量水,微沸回流1～3小时,回流提取2～3次；将提取液减压干燥为干浸膏,按照浸膏与辅料质量比为1∶1～1∶5的比例加入可溶性淀粉、蔗糖粉、糊精或乳糖,按浸膏与乙醇质量比为5∶1的比例加60％～90％的乙醇制成软材,软材过12～14号筛制成颗粒,在65℃干燥,整粒,即得葛根配方颗粒。本发明优点在于过程简单,产品中葛根素等活性成分含量高。将传统的葛根饮片改变为颗粒剂,可以有效地去除植物纤维等无活性成分,增加稳定性,易储存,服用方便。(The invention discloses a method for preparing kudzu root formula granules, which comprises the following formula: 100-200 parts of kudzuvine root tablet, 10-30 parts of starch, 5-25 parts of cane sugar, 5-20 parts of dextrin and 20-50 parts of lactose. The method comprises the following steps: adding water with the mass being 6-15 times of that of the radix puerariae decoction pieces, slightly boiling, refluxing for 1-3 hours, and refluxing and extracting for 2-3 times; and drying the extracting solution under reduced pressure to obtain dry extract, adding soluble starch, sucrose powder, dextrin or lactose according to the mass ratio of the extract to the auxiliary materials of 1: 1-1: 5, adding 60-90% of ethanol according to the mass ratio of the extract to the ethanol of 5: 1 to prepare soft materials, sieving the soft materials through a No. 12-14 sieve to prepare granules, drying at 65 ℃, and finishing granules to obtain the kudzu root formula granules. The invention has the advantages of simple process and high content of active ingredients such as puerarin in the product. The traditional radix puerariae decoction pieces are changed into granules, so that inactive ingredients such as plant fibers can be effectively removed, the stability is improved, the storage is easy, and the taking is convenient.)

1. A method for preparing kudzu root formula granules is characterized by comprising the following formula: 100-200 parts of kudzuvine root tablet, 10-30 parts of starch, 5-25 parts of cane sugar, 5-20 parts of dextrin and 20-50 parts of lactose. The method comprises the following steps: adding water with the mass being 6-15 times of that of the radix puerariae decoction pieces, slightly boiling, refluxing for 1-3 hours, and refluxing and extracting for 2-3 times; and drying the extracting solution under reduced pressure to obtain dry extract, adding soluble starch, sucrose powder, dextrin or lactose according to the mass ratio of the extract to the auxiliary materials of 1: 1-1: 5, adding 60-90% of ethanol according to the mass ratio of the extract to the ethanol of 5: 1 to prepare soft materials, sieving the soft materials through a No. 12-14 sieve to prepare granules, drying at 65 ℃, and finishing granules to obtain the kudzu root formula granules.

2. The method of claim 1, comprising the following formulation: 100 parts of kudzuvine root tablets, 10 parts of starch, 5 parts of cane sugar, 5 parts of dextrin and 20 parts of lactose. The method comprises the following steps: adding 6 times of water by mass into radix Puerariae decoction pieces, boiling slightly, refluxing for 1 hr, and reflux extracting for 2 times; and drying the extracting solution under reduced pressure to obtain dry extract, adding soluble starch, sucrose powder, dextrin or lactose according to the mass ratio of the extract to the auxiliary materials of 1: 1-1: 5, adding 60-90% of ethanol according to the mass ratio of the extract to the ethanol of 5: 1 to prepare soft materials, sieving the soft materials through a No. 12-14 sieve to prepare granules, drying at 65 ℃, and finishing granules to obtain the kudzu root formula granules.

3. The method of claim 1, comprising the following formulation: 150 parts of kudzu root slices, 20 parts of starch, 15 parts of cane sugar, 15 parts of dextrin and 30 parts of lactose. The method comprises the following steps: adding 10 times of water by mass into radix Puerariae decoction pieces, boiling slightly, refluxing for 2 hr, and reflux extracting for 2 times; and drying the extracting solution under reduced pressure to obtain dry extract, adding soluble starch, sucrose powder, dextrin or lactose according to the mass ratio of the extract to the auxiliary materials of 1: 1-1: 5, adding 60-90% of ethanol according to the mass ratio of the extract to the ethanol of 5: 1 to prepare soft materials, sieving the soft materials through a No. 12-14 sieve to prepare granules, drying at 65 ℃, and finishing granules to obtain the kudzu root formula granules.

4. The method of claim 1, comprising the following formulation: 200 parts of kudzuvine root tablets, 30 parts of starch, 25 parts of cane sugar, 20 parts of dextrin and 50 parts of lactose. The method comprises the following steps: adding 15 times of water by mass into the kudzuvine root decoction pieces, slightly boiling, refluxing for 3 hours, and extracting for 3 times by refluxing; and drying the extracting solution under reduced pressure to obtain dry extract, adding soluble starch, sucrose powder, dextrin or lactose according to the mass ratio of the extract to the auxiliary materials of 1: 1-1: 5, adding 60-90% of ethanol according to the mass ratio of the extract to the ethanol of 5: 1 to prepare soft materials, sieving the soft materials through a No. 12-14 sieve to prepare granules, drying at 65 ℃, and finishing granules to obtain the kudzu root formula granules.

Technical Field

The invention relates to a preparation method of traditional Chinese medicine formula granules, in particular to a method for preparing kudzuvine root formula granules.

Background

Radix Puerariae is a Chinese medicine with high medicinal value, has effects of relieving exterior syndrome, clearing heat, promoting fluid production, quenching thirst, and relieving diarrhea, and can be used for treating fever, anhidrosis, thirst, headache, and neck stiffness, measles without adequate eruption, diarrhea, dysentery, etc. The kudzu root is widely used for treating cardiovascular and cerebrovascular diseases such as coronary heart disease, angina pectoris, myocardial infarction, cerebral infarction and the like clinically, and has obvious curative effect and safe medication. Compared with traditional Chinese medicine decoction, the granule can effectively remove inactive ingredients such as plant fiber in decoction pieces, reduce dosage, increase stability, and has controllable quality, easy storage and convenient administration.

Disclosure of Invention

The invention aims to provide a method for preparing kudzuvine root formula particles, which aims to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme:

a method for preparing radix Puerariae granule comprises the following formula: 100-200 parts of kudzuvine root tablet, 10-30 parts of starch, 5-25 parts of cane sugar, 5-20 parts of dextrin and 20-50 parts of lactose. The method comprises the following steps: adding water with the mass being 6-15 times of that of the radix puerariae decoction pieces, slightly boiling, refluxing for 1-3 hours, and refluxing and extracting for 2-3 times; and drying the extracting solution under reduced pressure to obtain dry extract, adding soluble starch, sucrose powder, dextrin or lactose according to the mass ratio of the extract to the auxiliary materials of 1: 1-1: 5, adding 60-90% of ethanol according to the mass ratio of the extract to the ethanol of 5: 1 to prepare soft materials, sieving the soft materials through a No. 12-14 sieve to prepare granules, drying at 65 ℃, and finishing granules to obtain the kudzu root formula granules.

As a further scheme of the invention: the method for preparing the kudzuvine root formula granules comprises the following formula: 100 parts of kudzuvine root tablets, 10 parts of starch, 5 parts of cane sugar, 5 parts of dextrin and 20 parts of lactose. The method comprises the following steps: adding 6 times of water by mass into radix Puerariae decoction pieces, boiling slightly, refluxing for 1 hr, and reflux extracting for 2 times; and drying the extracting solution under reduced pressure to obtain dry extract, adding soluble starch, sucrose powder, dextrin or lactose according to the mass ratio of the extract to the auxiliary materials of 1: 1-1: 5, adding 60-90% of ethanol according to the mass ratio of the extract to the ethanol of 5: 1 to prepare soft materials, sieving the soft materials through a No. 12-14 sieve to prepare granules, drying at 65 ℃, and finishing granules to obtain the kudzu root formula granules.

As a still further scheme of the invention: the method for preparing the kudzuvine root formula granules comprises the following formula: 150 parts of kudzu root slices, 20 parts of starch, 15 parts of cane sugar, 15 parts of dextrin and 30 parts of lactose. The method comprises the following steps: adding 10 times of water by mass into radix Puerariae decoction pieces, boiling slightly, refluxing for 2 hr, and reflux extracting for 2 times; and drying the extracting solution under reduced pressure to obtain dry extract, adding soluble starch, sucrose powder, dextrin or lactose according to the mass ratio of the extract to the auxiliary materials of 1: 1-1: 5, adding 60-90% of ethanol according to the mass ratio of the extract to the ethanol of 5: 1 to prepare soft materials, sieving the soft materials through a No. 12-14 sieve to prepare granules, drying at 65 ℃, and finishing granules to obtain the kudzu root formula granules.

As a still further scheme of the invention: the method for preparing the kudzuvine root formula granules comprises the following formula: 200 parts of kudzuvine root tablets, 30 parts of starch, 25 parts of cane sugar, 20 parts of dextrin and 50 parts of lactose. The method comprises the following steps: adding 15 times of water by mass into the kudzuvine root decoction pieces, slightly boiling, refluxing for 3 hours, and extracting for 3 times by refluxing; and drying the extracting solution under reduced pressure to obtain dry extract, adding soluble starch, sucrose powder, dextrin or lactose according to the mass ratio of the extract to the auxiliary materials of 1: 1-1: 5, adding 60-90% of ethanol according to the mass ratio of the extract to the ethanol of 5: 1 to prepare soft materials, sieving the soft materials through a No. 12-14 sieve to prepare granules, drying at 65 ℃, and finishing granules to obtain the kudzu root formula granules.

Compared with the prior art, the invention has the beneficial effects that: the invention has the advantages of simple process and high content of active ingredients such as puerarin in the product. The traditional radix puerariae decoction pieces are changed into granules, so that inactive ingredients such as plant fibers can be effectively removed, the stability is improved, the storage is easy, and the taking is convenient.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.