阅读说明：本技术 一种祛风散寒、除湿通痹的组合物及其制备方法和用途 (Composition for expelling wind, clearing away cold, removing dampness and relieving arthralgia, preparation method and application thereof ) 是由 罗霞 于 2019-12-23 设计创作，主要内容包括：本发明提供了一种祛风散寒、除湿通痹的组合物及其制备方法和用途。该组合物是由如下重量配比的原料制备而成：牛膝10～20份,羌活5～15份,独活5～15份,桑寄生5～15份,杜仲2～8份,续断2～8份,狗脊5～15份,伸筋草2～8份,川芎5～15份,灵芝5～10份。本发明组合物具有祛风散寒、除湿通痹、强筋利骨的功效,能够有效缓解、甚至根治疗肌肉和关节的酸痛、僵硬。以本发明组合物为活性成分,可以用于制备具有祛风散寒、除湿通痹、强筋利骨功效,治疗或/和预防痛症的外用药物。同时,本发明使用的原料来源于中草药,成分天然、使用安全,可以用于制备治疗或/和预防痛症的日化用品,如化妆品,具有良好的应用前景。(The invention provides a composition for expelling wind, clearing away cold, removing dampness and relieving arthralgia, a preparation method and application thereof. The composition is prepared from the following raw materials in parts by weight: 10-20 parts of achyranthes bidentata, 5-15 parts of notopterygium roots, 5-15 parts of radix angelicae pubescentis, 5-15 parts of parasitic loranthus, 2-8 parts of eucommia ulmoides, 2-8 parts of teasel roots, 5-15 parts of rhizoma cibotii, 2-8 parts of lycopodium clavatum, 5-15 parts of ligusticum wallichii and 5-10 parts of lucid ganoderma. The composition has the effects of expelling wind and clearing away cold, removing dampness and freeing paralysis, and strengthening tendons and bones, and can effectively relieve, even radically cure and treat aching pain and stiffness of muscles and joints. The composition of the invention is used as an active ingredient and can be used for preparing external medicines which have the effects of expelling wind and removing cold, removing dampness and removing obstruction of vital energy and blood flow in the channels and collaterals and strengthening the muscles and bones and can treat or/and prevent pains. Meanwhile, the raw materials used by the invention are derived from Chinese herbal medicines, have natural components and safe use, can be used for preparing daily chemical products for treating or/and preventing pains, such as cosmetics, and have good application prospect.)

1. A composition for expelling wind, clearing away cold, removing dampness and relieving arthralgia is characterized in that: the composition is prepared from the following raw materials in parts by weight: 10-20 parts of achyranthes bidentata, 5-15 parts of notopterygium roots, 5-15 parts of radix angelicae pubescentis, 5-15 parts of parasitic loranthus, 2-8 parts of eucommia ulmoides, 2-8 parts of teasel roots, 5-15 parts of rhizoma cibotii, 2-8 parts of lycopodium clavatum, 5-15 parts of ligusticum wallichii and 5-10 parts of lucid ganoderma.

2. The composition of claim 1, wherein: the composition is prepared from the following raw materials in parts by weight: 15 parts of achyranthes root, 10 parts of notopterygium root, 10 parts of radix angelicae pubescentis, 10 parts of parasitic loranthus, 5 parts of eucommia bark, 5 parts of teasel root, 10 parts of rhizoma cibotii, 5 parts of lycopodium clavatum, 10 parts of ligusticum wallichii and 5 parts of lucid ganoderma.

3. A process for preparing the composition of claim 1 or 2, characterized in that: it comprises the following steps:

(1) weighing the raw material medicines according to the weight ratio;

(2) adding water into the raw material medicines, extracting for 2-3 times by refluxing, adding 20-30 times (v/w) of water each time, extracting for 30-60 min, filtering after extraction, and combining filtrates;

(3) concentrating the filtrate, adding flocculant, flocculating, filtering, and sterilizing.

4. The method of claim 3, wherein:

in the step (2), the reflux extraction is reflux extraction for 2 times, 20 times (v/w) of water is added each time, and the extraction is carried out for 30 min;

and/or, in the step (3), the concentrated extracting solution is concentrated to 12.5 times (v/w) of the weight of the raw material medicine;

and/or in the step (3), the flocculating agent is butanediol, the using amount of the flocculating agent is 0.9 per mill (w/v), and the flocculation condition is flocculation at 50 ℃ for 30 min;

and/or, in the step (3), filtering is carried out by a filter membrane of 0.45 μm after filtering by filter cloth;

and/or in the step (3), the sterilization is performed through a 0.22 mu m filter membrane.

5. Use of the composition of claim 1 or 2 for preparing an external medicine having the effects of expelling wind and removing cold, removing dampness and dredging arthralgia, and strengthening tendons and bones.

6. Use of the composition according to claim 1 or 2 for the preparation of a medicament for external use or a daily chemical product for the treatment or/and prevention of pain.

7. Use according to claim 6, characterized in that: the pain symptoms are stiff neck, soreness of waist and back, joint stabbing pain and muscle soreness.

8. A daily chemical article characterized by: the daily chemical product is prepared by taking the composition as an active ingredient in claim 1 or 2 and adding auxiliary materials or auxiliary ingredients commonly used in the daily chemical field.

9. A daily chemical article according to claim 8, wherein: the daily chemical product is a cosmetic.

10. A daily chemical article according to claim 9, wherein: the cosmetic is in the form of spray, lotion, liniment, unguent, cream, essence, essential oil, lotion, powder, pellicle, or patch.

Technical Field

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a composition for expelling wind and clearing away cold, and removing dampness and dredging paralysis, and a preparation method and application thereof.

Background

With the development of society, the change of living habits of people and the pain of joints and muscles become common phenomena. The stiff neck is easy to cause when the user looks at the mobile phone with his head down for a long time; prolonged sitting and lack of movement can lead to spinal deformity and soreness of the lumbar spine. In addition, joint stabbing pain and muscle soreness become serious with age and bone loss; long-term excessive exercise can also cause joint sprain and muscle strain, and pain occurs. General studies on the Global Pain Index (GPI) have shown that 94% of the nations are affected by joint and muscle pain. With six adults experiencing pain for as long as several hours or more per time.

From the perspective of traditional Chinese medicine, the cause of pain, namely pain, is basically two-fold: "obstructed" and "not honored". Obstruction is called arthralgia syndrome, which means that pathogenic qi blocks meridians and collaterals to obstruct the circulation of qi and blood, so that the obstruction of qi and blood circulation can cause pain. The so-called pathogenic qi refers to the abnormal climate change such as wind, cold, dampness and heat coming from the external environment, as mentioned in Huangdi's classic questions of the menstruation Bi syndrome: wind-damp-cold, three qi mixed into a whole, also called arthralgia. "can also refer to internal problems of the human body, such as qi stagnation and phlegm-dampness in the body caused by improper diet or lack of exercise, which can either affect the circulation of qi and blood in the meridians or collaterals alone or be accompanied by exogenous pathogens to affect the body, thus causing pain.

In life, common pain is common and very easy to ignore, but can have serious consequences, such as: the pain is aggravated to be difficult to treat, the dysfunction of each system of the body and the reduction of immunity are caused, complications are induced, even the patients are disabled or the lives of the patients are threatened, and the physical, psychological and life quality of the patients are seriously affected. Meanwhile, many pains cannot be cured radically, common plaster massage and the like have slight curative effect, and meanwhile, the plaster used in the traditional Chinese medicine for treating the pains has heavy taste and slow effect, and sensitive skin is easy to become red and itchy.

The traditional Chinese medicine daily chemical product is a medicine daily chemical product which is prepared from traditional Chinese medicines or is prepared by adding traditional Chinese medicines or traditional Chinese medicine active ingredients into chemical synthetic substances by taking the traditional Chinese medicine theory as guidance, is natural and green and also has certain efficacy. With the continuous pursuit of health, naturalness and greenness, the daily chemical products of the traditional Chinese medicine are popular with people. The number of daily chemical products of traditional Chinese medicine on the market is gradually increased, such as traditional Chinese medicine cosmetics. Among them, the famous traditional Chinese medicine cosmetics include overlord, herborist, etc.

At present, although the traditional Chinese medicine cosmetics on the market are various in types, most of the traditional Chinese medicine cosmetics have the effects of cleaning, maintaining and beautifying. There are few traditional Chinese medicine cosmetics which can treat and/or prevent pain and can relieve pain. If the traditional Chinese medicine cosmetic capable of relieving pain can be prepared, the pain can be relieved in daily life, and the market prospect is good.

Disclosure of Invention

The invention aims to provide a composition for expelling wind and clearing away cold, removing dampness and freeing paralysis, a preparation method and application thereof.

The invention provides a composition for expelling wind, clearing away cold, removing dampness and relieving arthralgia, which is prepared from the following raw materials in parts by weight: 10-20 parts of achyranthes bidentata, 5-15 parts of notopterygium roots, 5-15 parts of radix angelicae pubescentis, 5-15 parts of parasitic loranthus, 2-8 parts of eucommia ulmoides, 2-8 parts of teasel roots, 5-15 parts of rhizoma cibotii, 2-8 parts of lycopodium clavatum, 5-15 parts of ligusticum wallichii and 5-10 parts of lucid ganoderma.

Further, the composition is prepared from the following raw materials in parts by weight: 15 parts of achyranthes root, 10 parts of notopterygium root, 10 parts of radix angelicae pubescentis, 10 parts of parasitic loranthus, 5 parts of eucommia bark, 5 parts of teasel root, 10 parts of rhizoma cibotii, 5 parts of lycopodium clavatum, 10 parts of ligusticum wallichii and 5 parts of lucid ganoderma.

The present invention also provides a process for preparing the aforementioned composition, comprising the steps of:

(1) weighing the raw material medicines according to the weight ratio;

(2) adding water into the raw material medicines, extracting for 2-3 times by refluxing, adding 20-30 times (v/w) of water each time, extracting for 30-60 min, filtering after extraction, and combining filtrates;

(3) concentrating the filtrate, adding flocculant, flocculating, filtering, and sterilizing.

Further, the air conditioner is provided with a fan,

in the step (2), the reflux extraction is reflux extraction for 2 times, 20 times (v/w) of water is added each time, and the extraction is carried out for 30 min;

and/or, in the step (3), the concentrated extracting solution is concentrated to 12.5 times (v/w) of the weight of the raw material medicine;

and/or in the step (3), the flocculating agent is butanediol, the using amount of the flocculating agent is 0.9 per mill (w/v), and the flocculation condition is flocculation at 50 ℃ for 30 min;

and/or, in the step (3), filtering is carried out by a filter membrane of 0.45 μm after filtering by filter cloth;

and/or in the step (3), the sterilization is performed through a 0.22 mu m filter membrane.

The invention also provides application of the composition in preparing an external medicine with the effects of expelling wind and removing cold, removing dampness and freeing paralysis, and strengthening tendons and bones.

The invention also provides application of the composition in preparing an external medicine or a daily chemical product for treating or/and preventing pain.

Further, the pain symptoms are stiff neck, soreness of the waist and back, pricking pain of joints and soreness of muscles.

The invention also provides the daily chemical product which is prepared by taking the composition as an active ingredient and adding auxiliary materials or auxiliary ingredients commonly used in the daily chemical field.

Further, the daily chemical product is a cosmetic.

Further, the cosmetic is spray, lotion, liniment, ointment, cream, essence, essential oil, emulsion, powder, pellicle, patch.

The composition is prepared from ten medicines of achyranthes root, notopterygium root, pubescent angelica root, Chinese taxillus twig, eucommia bark, himalayan teasel root, east Asian tree fern rhizome, common clubmoss herb, Szechuan lovage rhizome and lucid ganoderma. In the prescription, the notopterygium root, the radix angelicae pubescentis and the ligusticum wallichii are used together to achieve the effects of expelling wind, removing cold, relieving pain, expelling wind-damp and benefiting joints as monarch drugs; because the kidney stores essence and governs bones, the waist is the house of the kidney, and the liver stores blood and governs tendons, the Chinese taxillus herb, the eucommia bark, the teasel root and the rhizoma cibotii are used together to achieve the effects of tonifying liver and kidney, strengthening bones and muscles, removing rheumatism, dredging channels and collaterals and relieving pain as ministerial drugs; the achyranthes root has the functions of promoting blood circulation, removing blood stasis, eliminating dampness, relieving pain, expelling wind and removing cold, the lycopodium clavatum has the functions of removing dampness, reducing swelling, relaxing tendons and activating collaterals, and the two medicines are used together to strengthen the functions of expelling wind and removing cold, removing dampness and relieving arthralgia. Ganoderma has effects in invigorating spleen, tranquilizing mind, and relieving pain.

The composition has the effects of expelling wind and clearing away cold, removing dampness and freeing paralysis, and strengthening tendons and bones, and can effectively relieve, even radically cure and treat aching pain and stiffness of muscles and joints. The composition of the invention is used as an active ingredient and can be used for preparing external medicines which have the effects of expelling wind and removing cold, removing dampness and removing obstruction of vital energy and blood flow in the channels and collaterals and strengthening the muscles and bones and can treat or/and prevent pains. Meanwhile, the raw materials used by the invention are derived from Chinese herbal medicines, have natural components and safe use, can be used for preparing daily chemical products for treating or/and preventing pains, such as cosmetics, and have good application prospect.

Obviously, many modifications, substitutions, and variations are possible in light of the above teachings of the invention, without departing from the basic technical spirit of the invention, as defined by the following claims.

The present invention will be described in further detail with reference to the following examples. This should not be understood as limiting the scope of the above-described subject matter of the present invention to the following examples. All the technologies realized based on the above contents of the present invention belong to the scope of the present invention.

Detailed Description

The raw materials and equipment used in the embodiment of the present invention are known products and obtained by purchasing commercially available products.