抗体、使用其的复合材料、检测装置和方法

文档序号:1563811 发布日期:2020-01-24 浏览:34次 >En<

阅读说明:本技术 抗体、使用其的复合材料、检测装置和方法 (Antibody, composite material using same, detection device, and detection method ) 是由 池内江美奈 于 2019-07-12 设计创作,主要内容包括:本发明涉及包含氨基酸序列的抗体,其中氨基酸序列按N至C方向包含以下结构域:N-FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4-C,其中FR指构架区氨基酸序列并且CDR指互补决定区氨基酸序列;CDR1包含由SEQ ID NO:1代表的氨基酸序列;CDR2包含由SEQ ID NO:2代表的氨基酸序列;和CDR3包含由SEQ ID NO:3代表的氨基酸序列。所述抗体能够与流感病毒的核内蛋白质结合。本发明还涉及含有所述抗体结合至选自固相支持物和标记物质中的至少一种的复合材料、包含所述复合材料和检测器的检测装置、以及基于复合材料和分析物中所含核内蛋白质的抗原-抗体反应检测物理量变化的检测方法。(The present invention relates to antibodies comprising an amino acid sequence comprising the following domains in the N to C direction: N-FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4-C, wherein FR denotes a framework region amino acid sequence and CDR denotes a complementarity determining region amino acid sequence; CDR1 comprises the amino acid sequence represented by SEQ ID NO. 1; CDR2 comprises the amino acid sequence represented by SEQ ID NO. 2; and CDR3 comprises the amino acid sequence represented by SEQ ID NO. 3. The antibody is capable of binding to an influenza virus nuclear protein. The present invention also relates to a composite material containing the antibody bound to at least one selected from the group consisting of a solid support and a labeling substance, a detection device comprising the composite material and a detector, and a detection method for detecting a change in a physical quantity based on an antigen-antibody reaction of the composite material and an intranuclear protein contained in an analyte.)

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