阅读说明：本技术 一种改善睡眠的调制乳粉及其制备方法 (Modified milk powder for improving sleep and preparation method thereof ) 是由 张岩春 戴智勇 汪家琦 潘丽娜 董玲 陈希苗 蒋怡乐 彭灿 于 2019-09-29 设计创作，主要内容包括：本发明提供了一种改善睡眠的调制乳粉。本发明提供的改善睡眠的调制乳粉,通过富含α-乳白蛋白牛乳清浓缩蛋白粉或富含α-乳白蛋白羊乳清浓缩蛋白粉、牛乳清蛋白水解肽粉或羊乳清蛋白水解肽粉、牛酪蛋白水解肽粉或羊酪蛋白水解肽粉、人乳低聚糖、人源益生菌、DHA、牛磺酸及缬草提取物等有效成分在体内起到各自功能,同时起到相互协同促进作用,既能合理的补营养,又能起到缓解精神压力及精神紧张、改善睡眠和调整肠道微生态的功能。本发明提供的改善睡眠的调制乳粉的制备方法,工艺合理,工艺参数易于控制,生产的产品质量稳定,合格率高。(The invention provides a modified milk powder for improving sleep. The modified milk powder for improving sleep provided by the invention has respective functions in vivo through effective components such as the concentrated bovine whey protein powder rich in alpha-lactalbumin or the concentrated goat whey protein powder rich in alpha-lactalbumin, the hydrolyzed peptide powder of bovine whey protein or the hydrolyzed peptide powder of goat whey protein, the hydrolyzed peptide powder of bovine casein or the hydrolyzed peptide powder of goat casein, human milk oligosaccharide, human probiotics, DHA, taurine and valerian extract, and has the function of mutual synergistic promotion, thereby not only supplementing nutrition reasonably, but also having the functions of relieving mental stress and mental stress, improving sleep and adjusting intestinal microecology. The preparation method of the modified milk powder for improving sleep provided by the invention has the advantages of reasonable process, easily controlled process parameters, stable quality of the produced product and high qualification rate.)

1. The modified milk powder for improving sleep is characterized by being prepared from the following raw materials in parts by weight:

30-50 parts of full-fat milk powder or full-fat sheep milk powder, 10-30 parts of concentrated albumen powder rich in alpha-lactalbumin and cow whey or concentrated albumen powder rich in alpha-lactalbumin and sheep whey, 5-15 parts of solid corn syrup or lactose or maltodextrin, 5-15 parts of hydrolyzed peptide powder of cow whey protein or hydrolyzed peptide powder of sheep whey protein, 5-12 parts of hydrolyzed peptide powder of cow casein or hydrolyzed peptide powder of sheep casein, 0.05-3 parts of human milk oligosaccharide, 0.02-0.5 part of human probiotic, 0-0.1 part of docosahexaenoic acid, 0.03-0.05 part of taurine, 0-0.3 part of soybean phospholipid, 0.1-1.5 parts of compound mineral substance, 0.1-1 part of compound vitamin and 0-0.5 part of valerian extract.

2. The modified milk powder of claim 1, wherein the alpha-lactalbumin-rich bovine whey protein concentrate or alpha-lactalbumin-rich sheep whey protein concentrate is an alpha-lactalbumin-rich protein concentrate with a protein content of 80% or more and an alpha-lactalbumin content of 25% or more, and the percentages are by weight.

3. The modified milk powder of claim 1, wherein the bovine whey protein hydrolysate or the sheep whey protein hydrolysate is a whey protein hydrolysate obtained by hydrolysis, separation, concentration, drying and the like of bovine whey protein or sheep whey protein serving as a raw material; the whey protein hydrolysate is peptides with a relative molecular mass less than or equal to 3000 dalton accounting for more than 70%.

4. The modified milk powder of claim 1, wherein the bovine casein hydrolysate powder or the ovine casein hydrolysate powder is a casein hydrolysate obtained by separating casein, hydrolyzing and spray-drying skim milk or skim sheep milk; the casein hydrolysate is peptide with relative molecular mass not more than 3000 dalton accounting for 70%.

5. The modified milk powder of claim 1, wherein the human milk oligosaccharide is 2 '-fucosyllactose, 3' -sialyllactose, 3 '-sialyl-N-acetyllactosamine, 6' -sialyllactose, 6 '-sialyl-N-acetyllactosamine, 3' -sialyl-3-fucosyllactose, disialyllactose, monofucosyl, monosialyllactose, lacto-N-trisaccharide, lacto-N-tetrasaccharide, lacto-N-neotetraose, sialyllacto-N-tetrasaccharide a, sialyllacto-N-tetrasaccharide b, sialyllacto-N-tetrasaccharide c, sialyllacto-N-tetrasaccharide d, disialyllactose-N-tetrasaccharide d, or the like, Lacto-difucotetraose, monosialyl, monofucolacto-N-tetraose, monosialyl, monofucolacto-N-neotetraose, trifucolacto-N-neotetraose I, lacto-N-fucopentaose II, lacto-N-fucopentaose III, lacto-N-fucopentaose VI, lacto-N-fucopentaose V, sialyl-lacto-N-fucopentaose V, lacto-N-neofucopentaose I, lacto-N-hexaose, p-lacto-N-hexaose, lacto-N-neohexaose, fuco-p-lacto-N-hexaose, bis-p-lacto-N-hexaose, mono-sialyl, mono-fucopentaose I, mono-sialyl-N-tetraose II, lacto-N-fucopentaose II, lacto-N-fucopentaose, monosialyl-lacto-N-neohexaose, monofucolacto-N-hexaose I, monofucolacto-N-hexaose III, difucolacto-N-hexaose a, difucolacto-N-hexaose b, difucolacto-N-hexaose c, difucolacto-N-neohexaose b, difuco-p-lacto-N-hexaose, monosialyl, difucolacto-N-neohexaose, difuco-p-lacto-N-neohexaose, difucolacto-N-hexaose, trifuco-lacto-N-hexaose, tri-p-lacto-N-hexaose, At least one of lacto-N-difucohexaose I, lacto-N-difucohexaose II, lacto-N-difucohexaose IV, lacto-N-neodifucohexaose II, para-lacto-N-neohexaose, lacto-N-neodecaose, and tri-fuco-iso-lacto-N-decaose.

6. The modified milk powder of claim 1, wherein the probiotic bacteria of human origin are one or more of bifidobacterium bifidum, bifidobacterium infantis, bifidobacterium adolescentis, bifidobacterium breve, bifidobacterium lactis, bifidobacterium longum, bifidobacterium animalis, lactobacillus acidophilus, lactobacillus rhamnosus, streptococcus lactis, lactococcus lactis, lactobacillus fermentum, lactobacillus casei, lactobacillus paracasei, lactobacillus gasseri, lactobacillus salivarius, and lactobacillus reuteri.

7. The modified milk powder of claim 1, wherein the docosahexaenoic acid is fish oil-derived DHA extract embedded powder or algae oil-derived DHA extract embedded powder;

the composite mineral substance meets the types and the addition amount of mineral substances which can be added into the modified milk powder, and the produced finished product meets the national standard requirement of the modified milk powder;

the compound vitamin meets the types and the addition amount of the vitamins which can be added in the modified milk powder, and the produced finished product meets the national standard requirement of the modified milk powder;

the extraction steps of the valerian extract comprise: pulverizing fresh or dried rhizoma et radix Valerianae, extracting with water under heating to obtain water extractive solution, and concentrating under reduced pressure; taking a water-soluble capsule material, adding a proper amount of water, heating and stirring to dissolve, and cooling to room temperature; adding the above concentrated extractive solution, stirring, mixing, spray granulating, and drying to obtain rhizoma et radix Valerianae extract.

8. A method for preparing the modified sleep powder milk according to any one of claims 1 to 7, comprising the steps of:

A) preparing materials:

mixing full-fat milk powder or full-fat sheep milk powder, concentrated alpha-lactalbumin-enriched milk whey protein powder or concentrated alpha-lactalbumin-enriched sheep whey protein powder, solid corn syrup or lactose or maltodextrin, hydrolyzed peptide powder of bovine whey protein or hydrolyzed peptide powder of sheep whey protein, hydrolyzed peptide powder of bovine casein or hydrolyzed peptide powder of sheep casein, docosahexaenoic acid, soybean phospholipid and valerian extract according to a predetermined proportion, adding 3-4 times of purified water with the weight of 40-55 ℃, uniformly stirring to obtain a first material, and pumping the first material into a temporary storage tank I;

or, mixing the concentrated protein powder rich in alpha-lactalbumin bovine whey or the concentrated protein powder rich in alpha-lactalbumin sheep whey, solid corn syrup or lactose or maltodextrin, hydrolyzed peptide powder of bovine whey protein or hydrolyzed peptide powder of sheep whey protein, hydrolyzed peptide powder of bovine casein or sheep casein, docosahexaenoic acid, soybean phospholipid and valerian extract according to a predetermined proportion, directly adding the mixture into full-fat bovine emulsion or full-fat sheep emulsion at the temperature of 40-55 ℃, and uniformly stirring to obtain a first material;

then, dissolving the vitamin complex and the compound mineral substances respectively in 8-12 times of purified water at 40-55 ℃ in advance according to a predetermined proportion, and uniformly mixing the dissolved vitamin complex and the compound mineral substances with the first material to obtain a second material;

B) sequentially shearing and filtering the second material, homogenizing, sterilizing, concentrating, spray drying and cooling with a fluidized bed to obtain base powder;

C) and adding the base powder, the human milk oligosaccharide, the humanized probiotics and the taurine into the base powder to obtain the modified milk powder for improving sleep.

9. A method for preparing the modified sleep powder milk according to any one of claims 1 to 7, comprising the steps of:

a) first-stage dry mixing:

according to the formula proportion, adding docosahexenoic acid powder, valerian extract, vitamin complex, compound mineral substances, human milk oligosaccharide, humanized probiotics, taurine, partial proportion of full-fat milk powder or full-fat goat milk powder, partial proportion of concentrated alpha-lactalbumin-enriched milk whey protein powder or concentrated alpha-lactalbumin-enriched goat milk whey protein powder, partial proportion of solid corn syrup or lactose or maltodextrin, partial proportion of hydrolyzed peptide powder of the milk whey protein or the goat milk albumin, partial proportion of hydrolyzed peptide powder of the milk casein protein or the hydrolyzed peptide powder of the goat casein protein into a three-dimensional mixer for uniformly mixing to obtain a first material, and conveying the first material into a high-speed mixer through dense phase;

b) second-stage dry mixing:

and putting the rest part of the whole milk powder or the whole sheep milk powder, the rest part of the concentrated protein powder rich in alpha-lactalbumin and bovine whey or the concentrated protein powder rich in alpha-lactalbumin and sheep whey, the rest part of the solid corn syrup or lactose or maltodextrin, the rest part of the hydrolyzed peptide powder of bovine whey protein or the hydrolyzed peptide powder of sheep whey protein, and the rest part of the hydrolyzed peptide powder of bovine casein or the hydrolyzed peptide powder of sheep casein into a high-speed mixer to be uniformly mixed with the first material to obtain the modified milk powder for improving sleep.

Technical Field

The invention belongs to the technical field of food, and particularly relates to modified milk powder for improving sleep and a preparation method thereof.

Background

The level of consciousness of a person is reduced or lost while sleeping, and most of the physiological activities and reactions enter a state of inertia. The fatigue nerve cells can recover normal physiological function, and the spirit and the physical strength can be recovered through sleeping. At present, the most common method for eliminating sleep disorder is to take hypnotics, but the drugs are resistant and addictive after being taken for a long time and have certain side effects. Therefore, the development of functional food which has the functions of resisting anxiety, improving sleep, reducing blood pressure, regulating the function of brain nerve cells, and safely and effectively improving sleep is of great significance. The sleep quality plays an important role in the aspects of the growth and development of children and teenagers and the health care of middle-aged and elderly people. Due to the study and work pressure of the people, the domestic pressure and the mood fluctuation in families, the problems of sleep disorder, poor sleep quality and the like generally exist. Prolonged sleep disturbance and poor sleep quality can lead to physical health related physiological and psychological disorders such as: the symptoms of insufficient energy, fatigue, anorexia, inattention, hypoimmunity, even physical weakness, mental hallucination, absentmindedness and the like occur, and the problems are extremely unfavorable for the normal physiological metabolism and the body functions of the human body. Therefore, the development of the modified milk powder for improving sleep has important practical significance and practical value.

Disclosure of Invention

In view of the above, the technical problem to be solved by the present invention is to provide a modified milk powder for improving sleep and a preparation method thereof, wherein the modified milk powder provided by the present invention not only has a nutritional effect on children, teenagers and middle-aged and elderly people, but also can improve the sleep quality of these people.

The invention provides modified milk powder for improving sleep, which is prepared from the following raw materials in parts by weight:

30-50 parts of full-fat milk powder or full-fat sheep milk powder, 10-30 parts of concentrated albumen powder rich in alpha-lactalbumin and cow whey or concentrated albumen powder rich in alpha-lactalbumin and sheep whey, 5-15 parts of solid corn syrup or lactose or maltodextrin, 5-15 parts of hydrolyzed peptide powder of cow whey protein or hydrolyzed peptide powder of sheep whey protein, 5-12 parts of hydrolyzed peptide powder of cow casein or hydrolyzed peptide powder of sheep casein, 0.05-3 parts of human milk oligosaccharide, 0.02-0.5 part of human probiotic, 0-0.1 part of docosahexaenoic acid, 0.03-0.05 part of taurine, 0-0.3 part of soybean phospholipid, 0.1-1.5 parts of compound mineral substance, 0.1-1 part of compound vitamin and 0-0.5 part of valerian extract.

Preferably, the alpha-lactalbumin-enriched bovine whey concentrated protein powder or the alpha-lactalbumin-enriched sheep whey concentrated protein powder is alpha-lactalbumin concentrated protein powder with the protein content of more than or equal to 80 percent and the alpha-lactalbumin of more than or equal to 25 percent, and the percentage is mass percentage.

Preferably, the bovine whey protein hydrolysate peptide powder or the sheep whey protein hydrolysate peptide powder is a whey protein hydrolysate obtained by taking bovine whey protein or sheep whey protein as a raw material and performing processes such as hydrolysis, separation, concentration, drying and the like; the whey protein hydrolysate is peptides with a relative molecular mass less than or equal to 3000 dalton accounting for more than 70%.

Preferably, the bovine casein hydrolysate powder or the sheep casein hydrolysate powder is a casein hydrolysate which is obtained by taking skim milk or skim sheep milk as a raw material and performing casein separation, hydrolysis and spray drying; the casein hydrolysate is peptide with relative molecular mass not more than 3000 dalton accounting for 70%.

Preferably, the human milk oligosaccharide is 2 '-fucosyllactose, 3' -sialyllactose, 3 '-sialyl-N-acetyllactosamine, 6' -sialyllactose, 6 '-sialyl-N-acetylated lactosamine, 3' -sialyl-3-fucosyllactose, disialyllactose, monofucosyl, monosialyllactose, lacto-N-trisaccharide, lacto-N-tetraose, lacto-N-neotetraose, sialyllacto-N-tetraose a, sialyllacto-N-tetraose b, sialyllacto-N-tetraose c, sialyllacto-N-tetraose d, disialyllacto-N-tetraose, lacto-difucotetraose, Monosialyl, monofucosyllacto-N-tetraose, monosialyl, monofucosyllacto-N-neotetraose, trifucosyllacto-N-neotetraose I, lacto-N-fucopentaose II, lacto-N-fucopentaose III, lacto-N-fucopentaose VI, lacto-N-fucopentaose V, sialyl-lacto-N-fucopentaose V, lacto-N-neofucopentaose I, lacto-N-hexaose, p-lacto-N-hexaose, lacto-N-neohexaose, fuco-p-lacto-N-hexaose, difuco-p-lacto-N-hexaose, di-lacto-N-hexaose, mono-sialyl, mono-fucosyllacto-N-tetraose, tri-N-fucopentaose, lacto-N, monosialyl-lacto-N-neohexaose, monofucolacto-N-hexaose I, monofucolacto-N-hexaose III, difucolacto-N-hexaose a, difucolacto-N-hexaose b, difucolacto-N-hexaose c, difucolacto-N-neohexaose b, difuco-p-lacto-N-hexaose, monosialyl, difucolacto-N-neohexaose, difuco-p-lacto-N-neohexaose, difucolacto-N-hexaose, trifuco-lacto-N-hexaose, tri-p-lacto-N-hexaose, At least one of lacto-N-difucohexaose I, lacto-N-difucohexaose II, lacto-N-difucohexaose IV, lacto-N-neodifucohexaose II, para-lacto-N-neohexaose, lacto-N-neodecaose, and tri-fuco-iso-lacto-N-decaose.

Preferably, the human-derived probiotics are one or more of bifidobacterium bifidum, bifidobacterium infantis, bifidobacterium adolescentis, bifidobacterium breve, bifidobacterium lactis, bifidobacterium longum, bifidobacterium animalis, lactobacillus acidophilus, lactobacillus rhamnosus, streptococcus lactis, lactococcus lactis, lactobacillus fermentum, lactobacillus casei, lactobacillus paracasei, lactobacillus gasseri, lactobacillus salivarius and lactobacillus reuteri.

Preferably, the docosahexaenoic acid is fish oil-derived DHA extract embedded powder or algae oil-derived DHA extract embedded powder;

the composite mineral substance meets the types and the addition amount of mineral substances which can be added into the modified milk powder, and the produced finished product meets the national standard requirement of the modified milk powder;

the compound vitamin meets the types and the addition amount of the vitamins which can be added in the modified milk powder, and the produced finished product meets the national standard requirement of the modified milk powder;

the extraction steps of the valerian extract comprise: pulverizing fresh or dried rhizoma et radix Valerianae, extracting with water under heating to obtain water extractive solution, and concentrating under reduced pressure. Taking a water-soluble capsule material, adding a proper amount of water, heating and stirring to dissolve, and cooling to room temperature; adding the above concentrated extractive solution, stirring, mixing, spray granulating, and drying to obtain rhizoma et radix Valerianae extract.

The invention also provides a preparation method of the modified milk powder for improving sleep, which comprises the following steps:

A) preparing materials:

mixing full-fat milk powder or full-fat sheep milk powder, concentrated alpha-lactalbumin-enriched milk whey protein powder or concentrated alpha-lactalbumin-enriched sheep whey protein powder, solid corn syrup or lactose or maltodextrin, hydrolyzed peptide powder of bovine whey protein or hydrolyzed peptide powder of sheep whey protein, hydrolyzed peptide powder of bovine casein or hydrolyzed peptide powder of sheep casein, soybean phospholipid docosahexaenoic acid and valerian extract according to a predetermined proportion, adding 3-4 times of purified water with the weight of 40-55 ℃, uniformly stirring to obtain a first material, and pumping the first material into a temporary storage tank I;

or, mixing the concentrated protein powder rich in alpha-lactalbumin bovine whey or the concentrated protein powder rich in alpha-lactalbumin sheep whey, solid corn syrup or lactose or maltodextrin, hydrolyzed peptide powder of bovine whey protein or hydrolyzed peptide powder of sheep whey protein, hydrolyzed peptide powder of bovine casein or sheep casein, docosahexaenoic acid, soybean phospholipid and valerian extract according to a predetermined proportion, directly adding the mixture into full-fat bovine emulsion or full-fat sheep emulsion at the temperature of 40-55 ℃, and uniformly stirring to obtain a first material;

then, dissolving the vitamin complex and the compound mineral substances respectively in 8-12 times of purified water at 40-55 ℃ in advance according to a predetermined proportion, and uniformly mixing the dissolved vitamin complex and the compound mineral substances with the first material to obtain a second material;

B) sequentially shearing and filtering the second material, homogenizing, sterilizing, concentrating, spray drying and cooling with a fluidized bed to obtain base powder;

C) and adding the base powder, the human milk oligosaccharide, the humanized probiotics and the taurine into the base powder to obtain the modified milk powder for improving sleep.

The invention also provides a preparation method of the modified milk powder for improving sleep, which comprises the following steps:

a) first-stage dry mixing:

according to the formula proportion, adding docosahexenoic acid powder, valerian extract, vitamin complex, compound mineral substances, human milk oligosaccharide, humanized probiotics, taurine, partial proportion of full-fat milk powder or full-fat goat milk powder, partial proportion of concentrated alpha-lactalbumin-enriched milk whey protein powder or concentrated alpha-lactalbumin-enriched goat milk whey protein powder, partial proportion of solid corn syrup or lactose or maltodextrin, partial proportion of hydrolyzed peptide powder of the milk whey protein or the goat milk albumin, partial proportion of hydrolyzed peptide powder of the milk casein protein or the hydrolyzed peptide powder of the goat casein protein into a three-dimensional mixer for uniformly mixing to obtain a first material, and conveying the first material into a high-speed mixer through dense phase;

b) second-stage dry mixing:

and putting the rest part of the whole milk powder or the whole sheep milk powder, the rest part of the concentrated protein powder rich in alpha-lactalbumin and bovine whey or the concentrated protein powder rich in alpha-lactalbumin and sheep whey, the rest part of the solid corn syrup or lactose or maltodextrin, the rest part of the hydrolyzed peptide powder of bovine whey protein or the hydrolyzed peptide powder of sheep whey protein, and the rest part of the hydrolyzed peptide powder of bovine casein or the hydrolyzed peptide powder of sheep casein into a high-speed mixer to be uniformly mixed with the first material to obtain the modified milk powder for improving sleep.

Compared with the prior art, the invention provides modified milk powder for improving sleep, which is prepared from the following raw materials in parts by weight: 30-50 parts of full-fat milk powder or full-fat sheep milk powder, 10-30 parts of concentrated albumen powder rich in alpha-lactalbumin and cow whey or concentrated albumen powder rich in alpha-lactalbumin and sheep whey, 5-15 parts of solid corn syrup or lactose or maltodextrin, 5-15 parts of hydrolyzed peptide powder of cow whey protein or hydrolyzed peptide powder of sheep whey protein, 5-12 parts of hydrolyzed peptide powder of cow casein or hydrolyzed peptide powder of sheep casein, 0.05-3 parts of human milk oligosaccharide, 0.02-0.5 part of human probiotic, 0-0.1 part of docosahexaenoic acid, 0.03-0.05 part of taurine, 0-0.3 part of soybean phospholipid, 0.1-1.5 parts of compound mineral substance, 0.1-1 part of compound vitamin and 0-0.5 part of valerian extract. The modified milk powder for improving sleep provided by the invention has respective functions in vivo through effective components such as the concentrated bovine whey protein powder rich in alpha-lactalbumin or the concentrated goat whey protein powder rich in alpha-lactalbumin, the hydrolyzed peptide powder of bovine whey protein or the hydrolyzed peptide powder of goat whey protein, the hydrolyzed peptide powder of bovine casein or the hydrolyzed peptide powder of goat casein, human milk oligosaccharide, human probiotics, DHA, taurine and valerian extract, and has the function of mutual synergistic promotion, thereby not only supplementing nutrition reasonably, but also having the functions of relieving mental stress and mental stress, improving sleep and adjusting intestinal microecology. The preparation method of the modified milk powder for improving sleep provided by the invention has the advantages of reasonable process, easily controlled process parameters, stable quality of the produced product and high qualification rate.

Detailed Description

The invention provides modified milk powder for improving sleep, which is prepared from the following raw materials in parts by weight:

30-50 parts of full-fat milk powder or full-fat sheep milk powder, 10-30 parts of concentrated albumen powder rich in alpha-lactalbumin and cow whey or concentrated albumen powder rich in alpha-lactalbumin and sheep whey, 5-15 parts of solid corn syrup or lactose or maltodextrin, 5-15 parts of hydrolyzed peptide powder of cow whey protein or hydrolyzed peptide powder of sheep whey protein, 5-12 parts of hydrolyzed peptide powder of cow casein or hydrolyzed peptide powder of sheep casein, 0.05-3 parts of human milk oligosaccharide, 0.02-0.5 part of human probiotic, 0-0.1 part of docosahexaenoic acid, 0.03-0.05 part of taurine, 0-0.3 part of soybean phospholipid, 0.1-1.5 parts of compound mineral substance, 0.1-1 part of compound vitamin and 0-0.5 part of valerian extract.

The preparation raw materials of the modified milk powder for improving sleep provided by the invention comprise 30-50 parts by weight of full-fat milk powder or full-fat goat milk powder, preferably 35-45 parts by weight, and more preferably 37-42 parts by weight. Wherein, the whole milk powder or the whole goat milk powder can be replaced by corresponding whole milk cow milk or whole goat milk. When the raw material is full-fat bovine milk or full-fat sheep milk, the weight of the full-fat bovine milk or the full-fat sheep milk is 8.3 (the weight of the full-fat bovine milk powder or the full-fat sheep milk powder).

The preparation raw materials of the modified milk powder for improving sleep comprise 10-30 parts by weight of concentrated alpha-lactalbumin-rich bovine whey protein powder or concentrated alpha-lactalbumin-rich sheep whey protein powder. The concentrated alpha-lactalbumin protein powder rich in bovine whey or the concentrated alpha-lactalbumin protein rich in sheep whey is the concentrated alpha-lactalbumin protein powder with the protein content of more than or equal to 80 percent and the alpha-lactalbumin of more than or equal to 25 percent, and the percentage is mass percent.

The whey protein rich in alpha-lactalbumin not only contains abundant tryptophan, but also has higher relative concentration of other essential amino acids. The alpha-lactalbumin prebiotic effect includes: the milk albumin containing the alpha-lactalbumin can better meet the requirement of essential amino acid by lower protein intake compared with the common milk albumin. Tryptophan plays an important role in the growth, development and metabolism of humans and is called the second essential amino acid. In vivo, the tryptophan can be used for synthesizing hormones such as 5-hydroxytryptamine, and physiologically active substances such as alkaloid and coenzyme, and can be used for preventing and treating pellagra, and relieving mental stress and improving sleep. The milk is rich in a biochemical substance capable of causing people to be tired and sleepy, and also contains trace morphine substances which have certain sedative and hypnotic effects. In particular, tryptophan is the main raw material for the brain to synthesize serotonin. Serotonin plays a key role in brain sleep, and can temporarily inhibit brain thought activity, so that people want to sleep without any side effect. In addition, the milk is well adhered to the stomach wall for absorption, and the calcium in the milk can also eliminate tension, so that the milk is more beneficial to the sleep of the old. Therefore, people can drink milk at night, and rest and sleep are facilitated.

The raw materials for preparing the modified milk powder for improving sleep also comprise 5-15 parts by weight of solid corn syrup or lactose or maltodextrin, preferably 7-13 parts by weight, and more preferably 9-11 parts by weight.

The raw materials for preparing the modified milk powder for improving sleep also comprise 5-15 parts by weight of bovine whey protein hydrolysate peptide powder or sheep whey protein hydrolysate peptide powder, preferably 7-13 parts by weight, and more preferably 9-11 parts by weight. The bovine whey protein hydrolysate peptide powder or the sheep whey protein hydrolysate peptide powder is a whey protein hydrolysate obtained by taking bovine whey protein or sheep whey protein as a raw material and performing the processes of hydrolysis, separation, concentration, drying and the like; the whey protein hydrolysate is peptides with a relative molecular mass less than or equal to 3000 dalton accounting for more than 70%.

The cow whey protein hydrolysate peptide powder or the sheep whey protein hydrolysate peptide powder not only reduces the allergenicity of protein nutrition, but also better promotes the absorption and utilization of protein. The bovine casein hydrolysate peptide powder or the sheep casein hydrolysate peptide powder is a pure natural, safe, effective and pressure-resistant food without toxic and side effects, for example, casein hydrolysate obtained from milk is easy to be absorbed by human bodies, and the sleep quality of testees can be improved. Sufficient sleep can not only eliminate fatigue, but also improve human immunity, better play the physiological function of organisms, improve the physical and mental health of human bodies and achieve the effects of strengthening brain and soothing nerves.

The raw materials for preparing the modified milk powder for improving sleep also comprise 5-12 parts by weight of bovine casein hydrolyzed peptide powder or sheep casein hydrolyzed peptide powder, preferably 6-11 parts by weight, and more preferably 7-10 parts by weight. The bovine casein hydrolyzed peptide powder or the sheep casein hydrolyzed peptide powder is a casein hydrolysate which is obtained by taking skim milk or skim sheep milk as a raw material and performing casein separation, hydrolysis and spray drying; the casein hydrolysate is peptide with relative molecular mass not more than 3000 dalton accounting for 70%.

The raw materials for preparing the modified milk powder for improving sleep also comprise 0.05-3 parts by weight of human milk oligosaccharide, preferably 0.1-2.5 parts by weight, and more preferably 0.5-2.0 parts by weight. The human milk oligosaccharide is 2 '-fucosyllactose, 3' -sialyllactose, 3 '-sialyl-N-acetyllactosamine, 6' -sialyllactose, 6 '-sialyl-N-acetyllactosamine, 3' -sialyl-3-fucosyllactose, disialoyllactose, monofucosyl, monosialyllactose, lacto-N-trisaccharide, lacto-N-tetraose, lacto-N-neotetraose, sialyllacto-N-tetraose a, sialyllacto-N-tetraose b, sialyllacto-N-tetraose c, sialyllacto-N-tetraose d, disialyllacto-N-tetraose, lacto-bis-tetraose, Monosialyl, monofucosyllacto-N-tetraose, monosialyl, monofucosyllacto-N-neotetraose, trifucosyllacto-N-neotetraose I, lacto-N-fucopentaose II, lacto-N-fucopentaose III, lacto-N-fucopentaose VI, lacto-N-fucopentaose V, sialyl-lacto-N-fucopentaose V, lacto-N-neofucopentaose I, lacto-N-hexaose, p-lacto-N-hexaose, lacto-N-neohexaose, fuco-p-lacto-N-hexaose, difuco-p-lacto-N-hexaose, di-lacto-N-hexaose, mono-sialyl, mono-fucosyllacto-N-tetraose, tri-N-fucopentaose, lacto-N, monosialyl-lacto-N-neohexaose, monofucolacto-N-hexaose I, monofucolacto-N-hexaose III, difucolacto-N-hexaose a, difucolacto-N-hexaose b, difucolacto-N-hexaose c, difucolacto-N-neohexaose b, difuco-p-lacto-N-hexaose, monosialyl, difucolacto-N-neohexaose, difuco-p-lacto-N-neohexaose, difucolacto-N-hexaose, trifuco-lacto-N-hexaose, tri-p-lacto-N-hexaose, At least one of lacto-N-difucohexaose I, lacto-N-difucohexaose II, lacto-N-difucohexaose IV, lacto-N-neodifucohexaose II, para-lacto-N-neohexaose, lacto-N-neodecaose, and tri-fuco-iso-lacto-N-decaose.

The functional effects of human milk oligosaccharides, also known as human milk oligosaccharides, are attributable to the presence of various bioactive factors in breast milk. Human Milk Oligosaccharides (HMOs) are the third largest solid component in human breast milk to lactose and fat only. HMO has high level in colostrum, which can reach 22-23g/L, and the concentration of the HMO in the colostrum is reduced and stabilized at 12-13g/L in the normal milk 2 months after parturition and lactation. Since the monosaccharide and glycosidic bond constituting human milk oligosaccharide are different in connection mode, the human milk oligosaccharide is complex and diverse in structure and function, and more than 200 kinds of oligosaccharide are proved to be contained in human milk at present.

The preparation raw materials of the modified milk powder for improving sleep also comprise 0.02-0.5 part by weight of human-derived probiotics, preferably 0.05-0.45 part by weight, and more preferably 0.15-0.35 part by weight. The human-derived probiotics is one or more of bifidobacterium bifidum, bifidobacterium infantis, bifidobacterium adolescentis, bifidobacterium breve, bifidobacterium lactis, bifidobacterium longum, bifidobacterium animalis, lactobacillus acidophilus, lactobacillus rhamnosus, streptococcus lactis, lactococcus lactis, lactobacillus fermentum, lactobacillus casei, lactobacillus paracasei, lactobacillus gasseri, lactobacillus salivarius and lactobacillus reuteri.

The human-derived probiotics are active microorganisms which can regulate the micro-ecological balance of the intestinal tract of a human body, have beneficial effect on the health of the human body and are derived from the human body. From the last century, people have realized that microorganisms and metabolites thereof can affect the organism, and screened from the human body to obtain many times of microorganisms considered beneficial probiotics, so that many of the microorganisms become well-known probiotics and create great economic and social values.

The raw materials for preparing the modified milk powder for improving sleep also comprise 0-0.1 weight part of docosahexaenoic acid (DHA), preferably 0.02-0.08 weight part, and more preferably 0.04-0.06 weight part. The docosahexaenoic acid is fish oil source DHA extract embedded powder or algae oil source DHA extract embedded powder. Docosahexaenoic acid (DHA) is derived from fish oil and fish oil extracts or from algae DHA extracts, wherein the fish oil DHA is rich in omega-3 fatty acids such as EPA, DHA and the like, the algae oil DHA is rich in omega-3 fatty acids which can sufficiently nourish cells, and the DHA is an essential fatty acid essential for brain and nerve cell activities.

The preparation raw materials of the modified milk powder for improving sleep also comprise 0.03-0.05 part by weight of taurine, and preferably 0.04-0.05 part by weight.

The preparation raw materials of the modified milk powder for improving sleep also comprise 0-0.3 weight part of soybean lecithin, preferably 0.05-0.25 weight part, and more preferably 0.1-0.2 weight part.

The raw materials for preparing the modified milk powder for improving sleep also comprise 0-0.5 weight part of valerian extract, preferably 0.1-0.4 weight part, and more preferably 0.2-0.3 weight part. The extraction steps of the valerian extract comprise: pulverizing fresh or dried rhizoma et radix Valerianae, extracting with water under heating to obtain water extractive solution, and concentrating under reduced pressure. Taking a water-soluble capsule wall material, adding a proper amount of water, heating and stirring to dissolve the water-soluble capsule wall material, and cooling to room temperature; adding the above concentrated extractive solution, stirring, mixing, spray granulating, and drying to obtain rhizoma et radix Valerianae extract.

Valerian belongs to the genus Valerianaceae (Valerianaceae) Valeriana (Valerianal.) perennial herbaceous plants of more than 250 species, distributed mainly in the continental Europe, south America and North America. Valeriana officinalis is about 30 in China, and is mainly distributed in southwest and northeast regions. As described earlier in Ben Cao gang mu of the Ming Dynasty, Valeriana officinalis is sweet and neutral in nature and its rhizome has been used as analgesic and hypnotic in folk. In 1966, the valerian triester component is firstly separated from valerian, and is the earliest obtained iridoid ester compound, and the component is preliminarily proved to be a main active substance with sedative effect and simultaneously has various biological activities such as cytotoxicity, tumor resistance and the like. Experiments prove that main components of valerian extract, valerenic acid and valerenol, can enhance the reaction of gamma-aminobutyric acid (GABA) receptors. Experiments show that the serum corticosterone level of rats in the administration groups (valerenic acid and valerenol) is also obviously reduced, which indicates that the valerian has obvious anxiolytic effect. The valerian is a green sleeping aid without toxic and side effects, is widely used for sedation, hypnosis and convulsion resistance at home and abroad, and can lead the emotion of people to become mild.

The preparation raw materials of the modified milk powder for improving sleep also comprise 0.1-1.5 parts by weight of composite minerals, preferably 0.5-1.0 part by weight, and more preferably 0.6-0.9 part by weight. The composite mineral substance meets the types and the addition amount of mineral substances which can be added into the modified milk powder, and the produced finished product meets the national standard requirements of the modified milk powder.

The raw materials for preparing the modified milk powder for improving sleep also comprise 0.1-1 part by weight of composite vitamin, preferably 0.3-0.8 part by weight, and more preferably 0.4-0.7 part by weight. The compound vitamin meets the types and the addition amount of the vitamins which can be added in the modified milk powder, and the produced finished product meets the national standard requirement of the modified milk powder.

The invention also provides a preparation method of the modified milk powder for improving sleep, which comprises the following steps:

A) preparing materials:

mixing full-fat milk powder or full-fat sheep milk powder, concentrated alpha-lactalbumin-enriched milk whey protein powder or concentrated alpha-lactalbumin-enriched sheep whey protein powder, solid corn syrup or lactose or maltodextrin, hydrolyzed peptide powder of bovine whey protein or hydrolyzed peptide powder of sheep whey protein, hydrolyzed peptide powder of bovine casein or hydrolyzed peptide powder of sheep casein, docosahexaenoic acid powder, soybean phospholipid and valerian extract according to a predetermined proportion, adding 3-4 times of purified water with the weight of 40-55 ℃, stirring uniformly to obtain a first material, and pumping the first material into a temporary storage tank I;

or, mixing the concentrated alpha-lactalbumin-enriched bovine whey protein powder or the concentrated alpha-lactalbumin-enriched sheep whey protein powder, solid corn syrup or lactose or maltodextrin, bovine whey protein hydrolysate peptide powder or sheep whey protein hydrolysate peptide powder, bovine casein hydrolysate peptide powder or sheep casein hydrolysate peptide powder, docosahexenoic acid powder, soybean phospholipid and valerian extract according to a predetermined proportion, directly adding the mixture into full-fat bovine emulsion or full-fat sheep emulsion at the temperature of 40-55 ℃, and uniformly stirring to obtain a first material;

then, dissolving the vitamin complex and the compound mineral substances respectively in 8-12 times of purified water at 40-55 ℃ in advance according to a predetermined proportion, and uniformly mixing the dissolved vitamin complex and the compound mineral substances with the first material to obtain a second material;

B) sequentially shearing and filtering the second material, homogenizing, sterilizing, concentrating, spray drying and cooling with a fluidized bed to obtain base powder;

specifically, the shearing and filtering are as follows:

placing the second mixed material in a high-speed shearing tank through a proportioning pump or directly pouring the second mixed material into the high-speed shearing tank, stirring for 8-15 minutes, and pumping the second mixed material into the proportioning tank through a duplex filter to obtain a third material;

wherein, the stirring of the batching tank should be kept in a continuous stirring state, so as to ensure the even mixing of the batching liquid and prevent the batching layering;

homogenizing:

homogenizing the third material at the temperature of 55-65 ℃ and the pressure of 20-25 MPa to obtain a fourth material;

the sterilization comprises the following steps:

sterilizing the fourth material at 85-95 ℃ for 18-25 seconds to obtain a fifth material;

concentrating to obtain:

concentrating the sterilized fifth material to a concentration of 20-24 Baume under the conditions of a vacuum degree of-21 to-8 kPa and a temperature of 55-62 ℃ to obtain a sixth material;

the spray drying comprises the following steps:

spray drying the sixth material under the conditions that the pressure is 15-20 MPa, the feeding air inlet temperature is 175-200 ℃ and the exhaust air temperature is 80-90 ℃ to obtain a seventh material;

the bean jelly in the fluidized bed is as follows:

and cooling the seventh material to be close to room temperature through a fluidized bed, wherein the water content in the seventh material is 2.5-5.0 wt%, and thus the modified milk powder base powder for improving sleep is obtained, and the eighth material is obtained.

C) And adding the base powder, the human milk oligosaccharide, the humanized probiotics and the taurine into the base powder to obtain the modified milk powder for improving sleep.

The invention can also adopt a dry mixing method to prepare the modified milk powder for improving sleep, which comprises the following steps:

a) first-stage dry mixing:

according to the formula proportion, adding docosahexenoic acid powder (fish oil extract or algae oil extract embedded powder), valerian extract, compound vitamins, compound minerals, human milk oligosaccharides, humanized probiotics, taurine, partial proportion of full-fat milk powder or full-fat sheep milk powder, partial proportion of alpha-lactalbumin-rich bovine whey concentrated protein powder or alpha-lactalbumin-rich sheep whey concentrated protein powder, partial proportion of solid corn syrup or lactose or maltodextrin, partial proportion of bovine whey protein hydrolyzed peptide powder or sheep whey protein hydrolyzed peptide powder and partial proportion of bovine casein protein hydrolyzed peptide powder or sheep casein protein hydrolyzed peptide powder into a three-dimensional mixer for uniformly mixing to obtain a first material, and conveying the first material into a high-speed mixer through a dense phase;

b) second-stage dry mixing:

and putting the rest part of the whole milk powder or the whole sheep milk powder, the rest part of the concentrated protein powder rich in alpha-lactalbumin and bovine whey or the concentrated protein powder rich in alpha-lactalbumin and sheep whey, the rest part of the solid corn syrup or lactose or maltodextrin, the rest part of the hydrolyzed peptide powder of bovine whey protein or the hydrolyzed peptide powder of sheep whey protein, and the rest part of the hydrolyzed peptide powder of bovine casein or the hydrolyzed peptide powder of sheep casein into a high-speed mixer to be uniformly mixed with the first material to obtain the modified milk powder for improving sleep.

The modified milk powder for improving sleep provided by the invention has respective functions in vivo through effective components such as the concentrated bovine whey protein powder rich in alpha-lactalbumin or the concentrated goat whey protein powder rich in alpha-lactalbumin, the hydrolyzed peptide powder of bovine whey protein or the hydrolyzed peptide powder of goat whey protein, the hydrolyzed peptide powder of bovine casein or the hydrolyzed peptide powder of goat casein, human milk oligosaccharide, human probiotics, DHA, taurine and valerian extract, and has the function of mutual synergistic promotion, thereby not only supplementing nutrition reasonably, but also having the functions of relieving mental stress and mental stress, improving sleep and adjusting intestinal microecology. The modified milk powder is a good choice of food for improving sleep, has nutrition effect on children, teenagers and middle-aged and elderly people, and can improve sleep quality of the people. The preparation method of the modified milk powder for improving sleep provided by the invention has the advantages of reasonable process, easily controlled process parameters, stable quality of the produced product and high qualification rate.

For further understanding of the present invention, the modified milk powder for improving sleep and the preparation method thereof provided by the present invention are described below with reference to the following examples, and the scope of the present invention is not limited by the following examples.

The specific preparation method of the bovine whey protein hydrolyzed peptide powder used in the following examples and comparative examples:

the method is characterized in that bovine whey protein powder is taken as a raw material, dissolved in water and subjected to ultrasonic treatment, and then papain is utilized under the condition that no acid or alkali is added: neutral protease: the flavourzyme is prepared by mixing 1: 1: 1, performing composite enzymolysis at 50-65 ℃ for 2.0 hours to change macromolecular proteins into peptides, inactivating enzymes of zymolyte, cooling, filtering and separating, performing membrane separation and ultrafiltration (adopting a 10kDa ultrafiltration membrane) to separate, concentrating the separated peptide solution, and performing spray drying to finally obtain the bovine whey protein peptide powder.

The bovine whey protein hydrolyzed peptide powder is peptides with the relative molecular mass less than or equal to 3000 daltons and accounts for more than 70%.

The specific preparation method of bovine casein hydrolysate peptide powder used in the following examples and comparative examples:

dissolving bovine casein powder serving as a raw material in water, performing ultrasonic treatment, adjusting the pH value to 1.5-4.0, adding pepsin, and performing hydrolysis reaction at the temperature of 50-60 ℃ for 1-2 hours; keeping the temperature of the hydrolysis reaction system unchanged, adjusting the pH value of the system to 6.0-8.0, adding trypsin, and continuing to hydrolyze for 1-2 hours. Heating the reaction system to 85-90 ℃, and keeping for 25-30 min to obtain the bovine casein hydrolysate; inactivating enzyme, cooling, filtering, separating with membrane separation ultrafiltration (10kDa ultrafiltration membrane), concentrating the separated peptide solution, and spray drying to obtain bovine casein peptide powder.

The bovine casein hydrolyzed peptide powder is polypeptide with the molecular weight less than or equal to 3000 daltons and accounts for more than 70%.

The specific preparation method of the sheep whey protein hydrolysate peptide powder used in the following examples and comparative examples:

the method is characterized in that sheep whey protein powder is used as a raw material, water is added for dissolving, ultrasonic treatment is carried out, and then papain is utilized under the condition that no acid or alkali is added: neutral protease: the flavourzyme is prepared by mixing 1: 1: 1, performing composite enzymolysis at 50-65 ℃ for 2.0 hours to change macromolecular proteins into peptides, inactivating enzymes of zymolyte, cooling, filtering and separating, performing membrane separation and ultrafiltration (adopting a 10kDa ultrafiltration membrane) to separate, concentrating the separated peptide solution, and performing spray drying to finally obtain the sheep whey protein peptide powder.

The sheep whey protein hydrolysis peptide powder is peptides with the relative molecular mass less than or equal to 3000 daltons and accounts for more than 70%.

The specific preparation method of the sheep casein hydrolysate peptide powder used in the following examples and comparative examples:

dissolving feta protein powder serving as a raw material in water, performing ultrasonic treatment, adjusting the pH value to 1.5-4.0, adding pepsin, and performing hydrolysis reaction at the temperature of 50-60 ℃ for 1-2 hours; keeping the temperature of the hydrolysis reaction system unchanged, adjusting the pH value of the system to 6.0-8.0, adding trypsin, and continuing to hydrolyze for 1-2 hours. Heating the reaction system to 85-90 ℃, and keeping for 25-30 min to obtain feta protein hydrolysate; inactivating enzyme, cooling, filtering, separating with membrane separation ultrafiltration (10kDa ultrafiltration membrane), concentrating the separated peptide solution, and spray drying to obtain sheep casein peptide powder.

The sheep casein hydrolyzed peptide powder is polypeptide with molecular weight less than or equal to 3000 dalton accounting for more than 70%.

The specific preparation method of valerian extracts used in the following examples and comparative examples was:

the valerian extract is prepared from the root and rhizome of valerian of Valerianaceae by extracting with water, concentrating, and spray drying, wherein the valerian acid content is 0.55%.