阅读说明：本技术 预防龋齿的儿童咀嚼型口香糖及其制备方法 (Children chewing gum for preventing dental caries and preparation method thereof ) 是由 董志红 龚家宝 于 2019-09-24 设计创作，主要内容包括：本发明公开了预防龋齿的儿童咀嚼型口香糖及其制备方法,包括以下步骤：步骤一：将胶基重量比为15％-30％在40°下加热3-5小时后,分1/2批次依次加入香精重量比为0.5-2％,甘油重量比为0.7％-1.5％,70％山梨醇重量比为5-15％,麦芽糊精重量比为3-8％和生物活性材料重量比为5-25％；步骤二：搅拌均匀,将混合料液加热至45°左右,冷却压制成型,包装；步骤三：将材料选择后,进行干燥,过200目筛子,将水含量控制在4％-5％以内,通过造粒机以湿法进行加工造粒,即获得口香糖；解决了以往不健康饮食直接破坏牙釉质,使牙齿表面的矿物质软化,松动,严重的导致矿物质脱落,露出牙本质,进而导致龋齿的问题。(The invention discloses a children chewing gum for preventing decayed teeth and a preparation method thereof, wherein the children chewing gum comprises the following steps: the method comprises the following steps: heating gum base 15-30 wt% at 40 deg.C for 3-5 hr, sequentially adding 1/2 batches of essence 0.5-2 wt%, glycerin 0.7-1.5 wt%, 70% sorbitol 5-15 wt%, maltodextrin 3-8 wt% and bioactive material 5-25 wt%; step two: stirring, heating the mixed solution to about 45 deg.C, cooling, press-forming, and packaging; step three: selecting materials, drying, sieving with a 200-mesh sieve, controlling the water content within 4% -5%, and processing and granulating by a wet method through a granulator to obtain the chewing gum; solves the problems that the traditional unhealthy diet directly destroys enamel, softens and loosens minerals on the surface of teeth, seriously causes the minerals to fall off, exposes dentin and further causes dental caries.)

1. The preparation method of the children chewing gum for preventing the decayed teeth is characterized by comprising the following steps:

step S1: heating gum base 15-30 wt% at 40 deg.C for 3-5 hr, sequentially adding 1/2 batches of essence 0.5-2 wt%, glycerin 0.7-1.5 wt%, 70% sorbitol 5-15 wt%, maltodextrin 3-8 wt% and bioactive material 5-25 wt%;

step S2: stirring uniformly, heating the mixed liquid to 45 ℃, cooling, pressing, molding and packaging;

step S3: selecting materials, drying, sieving with a 200-mesh sieve, controlling the water content within 4% -5%, and processing and granulating by a wet method through a granulator to obtain the chewing gum.

2. The children chewing gum for preventing the decayed tooth is characterized by comprising the following conventional chewing gum formula raw materials in percentage by weight: 15 to 30 percent; the essence comprises the following components in percentage by weight: 0.5-2%; the weight ratio of the glycerol is 0.7-1.5%; 70% sorbitol 5-15%, maltodextrin 3-8%, and bioactive material 5-25%.

3. The children's chewing gum for preventing dental caries according to claim 2, wherein the particle size of the bioactive material is controlled in nano and micro sizes of 100-500nm and 1-5um, respectively, and the bioactive material is a biomedical ceramic material.

4. The children chewing gum for preventing the decayed teeth as claimed in claim 2, wherein the essence is a sweetening agent, and the sweetening agent is one or more of essence, cane sugar and acesulfame; the glycerin is a humectant which is one or more of glycerin, sorbitol and polyethylene glycol; the maltodextrin is used for adjusting viscosity.

5. The children's chewing gum for preventing dental caries according to claim 2, wherein the children's chewing gum for preventing dental caries is used for releasing bioactive materials while chewing the children's chewing gum for preventing dental caries, restoring acid-etched enamel under the action of saliva, and protecting the loss of tooth minerals.

Technical Field

The invention relates to the field of food and medicine, in particular to children chewing gum for preventing decayed teeth and a preparation method thereof.

Background

Oral health atlas issued by world subfamily alliance (FDI) in 2015: challenges in oral disease-call for global action reports that 60-90% of children are suffering from dental caries, but most children are not effectively treated due to conditions for oral health, economic reasons, and lack of oral professional skills. In particular, children in developing countries, such as argentina, have caries, and in our country, epidemiological findings from the fourth oral health show: the prevalence of children in the 12 year old age group has risen from 28.9% by 10 years to 38.5% by 2015, with a rise of nearly 10%. The children in rural areas rise more obviously from 28.6% to 40%; the causes of dental caries are many, such as unhealthy diet, bad oral hygiene, excessive intake of sugar, and various carbonated drinks. Can directly damage enamel, soften and loosen mineral substances on the surface of teeth, seriously cause the mineral to fall off and expose dentin. Leading to dental caries. The development of caries is a progressive process, and children do not brush their teeth properly, resulting in more food residues left on the teeth. The outer most hard enamel layer, if damaged, is extremely susceptible to erosion because it contains one third as much inorganic mineral content as enamel. Therefore, protecting the tooth enamel is the primary barrier to caries. Moreover, teeth are different from bones, although they are comparable in composition, and can regenerate, while enamel, which is the outermost layer of teeth, has no nerves and blood vessels and cannot regenerate after being damaged. Therefore, it is crucial to protect their teeth.

How to improve the environmental sanitation of children oral cavity is a problem to be solved urgently at present. The products aiming at protecting and repairing the teeth of children in the market are few, and the toothpaste for children and children cannot brush teeth correctly, so that the efficacy is not satisfactory. At present, frequent chewing of chewing gum is a good choice, in addition to regular gargling. Because the children often chew the chewing gum, the facial muscles of the children, such as masticatory muscles, can be exercised, and temporomandibular joints can be moved, so that the facial muscle lines can be displayed conveniently. Meanwhile, the teeth can be firmer, and the secretion of digestive juice can be directly stimulated during continuous chewing, so that the appetite of children is improved. Especially the effective components in the chewing gum can repair the acid etched enamel to a certain extent and improve the remineralization effect of the teeth.

Biomedical ceramic materials, such as calcium-silicon-based (e.g., calcium silicate, fluorine-based calcium silicate, bioglass) and calcium-phosphorus-based (e.g., tricalcium phosphate) materials, have been widely used clinically as a repair and replacement for artificial bones. The material has good biological activity and osteoinductivity, and can form new mineralized phase-nano hydroxyapatite in the environment of simulated body fluid, and the component is mainly the main component of teeth and bones. In the process of inducing the formation of apatite, the fluorine ion radius is smaller than that of hydroxyl, so that the surface area of the formed fluorine-based apatite crystal is smaller, the fluorine-based calcium silicate is more compact and firmer, and the erosion of foreign substances can be improved. And the addition of fluorine can accelerate the deposition of apatite, improve the crystallinity of crystals, arrange the crystals more orderly and accelerate the remineralization of glaze.

Disclosure of Invention

In order to solve the problems in the prior art, the invention provides the children chewing gum for preventing the decayed tooth and the preparation method thereof, and solves the problems that the original unhealthy diet directly destroys the enamel of teeth, causes the minerals on the surfaces of the teeth to soften and loosen, seriously causes the minerals to fall off, exposes the dentin and further causes the decayed tooth.

The invention adopts the technical scheme that the preparation method of the children chewing gum for preventing decayed teeth comprises the following steps:

step S1: heating gum base 15-30 wt% at 40 deg.C for 3-5 hr, sequentially adding 1/2 batches of essence 0.5-2 wt%, glycerin 0.7-1.5 wt%, 70% sorbitol 5-15 wt%, maltodextrin 3-8 wt% and bioactive material 5-25 wt%;

step S2: stirring uniformly, heating the mixed liquid to 45 ℃, cooling, pressing, molding and packaging;

step S3: selecting materials, drying, sieving with a 200-mesh sieve, controlling the water content within 4% -5%, and processing and granulating by a wet method through a granulator to obtain the chewing gum.

Preferably, the children chewing gum for preventing the decayed teeth comprises the following conventional chewing gum formula raw materials in percentage by weight: 15 to 30 percent; the essence comprises the following components in percentage by weight: 0.5-2%; 0.7-1.5% of glycerin by weight; 70% sorbitol 5-15%, maltodextrin 3-8%, and bioactive material 5-25%.

Preferably, the particle size of the bioactive material can be controlled between nanometer and micrometer, 100-500nm and 1-5um respectively.

Preferably, the essence is a sweetening agent, and the sweetening agent is one or more of essence, sucrose and acesulfame; glycerin is used as humectant, which is one or more of glycerin, sorbitol and polyethylene glycol; maltodextrin is used for regulating viscosity.

Preferably, the children chewing gum for preventing the decayed tooth is used for releasing the bioactive material while chewing the children chewing gum for preventing the decayed tooth, repairing the acid-etched enamel under the action of saliva and protecting the loss of tooth mineral substances.

The children chewing gum for preventing decayed teeth and the preparation method thereof have the following beneficial effects:

the product of the invention has the characteristics of chewing gum and also has the repairing effect, and because the added bioactive materials have the obvious symptoms of repairing demineralized enamel, mineral loosening and the like, the product can prevent the occurrence of early decayed teeth of children.

Drawings

FIG. 1 is a scanning electron microscope observation chart of a chewing gum for children for preventing dental caries, which is obtained by soaking deciduous teeth in coca-cola for 1 minute, simulating chewing gum form, 10 minutes, and soaking in saliva simulating oral cavity for 48 hours

FIG. 2 is a graph showing the tooth restoration effect of chewing gum made of bioactive materials containing different components in simulated oral saliva environment for 48 hours, according to the chewing gum for children for preventing dental caries and the preparation method thereof

FIG. 3 is an XRD pattern of a children chewing gum for preventing dental caries and a preparation method thereof, which is prepared by adding 5% of active materials into the chewing gum, and repairing the surface of enamel after simulated chewing of acid-etched enamel for 48 hours

FIG. 4 is a block diagram of a children's chewing gum for preventing dental caries and a method for preparing the same according to the present invention

Detailed Description

The following description of the embodiments of the present invention is provided to facilitate the understanding of the present invention by those skilled in the art, but it should be understood that the present invention is not limited to the scope of the embodiments, and it will be apparent to those skilled in the art that various changes may be made without departing from the spirit and scope of the invention as defined and defined in the appended claims, and all matters produced by the invention using the inventive concept are protected.

As shown in fig. 4, the method for preparing children's chewing gum for preventing dental caries includes the following steps:

step S1: heating gum base 15-30 wt% at 40 deg.C for 3-5 hr, sequentially adding 1/2 batches of essence 0.5-2 wt%, glycerin 0.7-1.5 wt%, 70% sorbitol 5-15 wt%, maltodextrin 3-8 wt% and bioactive material 5-25 wt%;

step S2: stirring, heating the mixed solution to about 45 deg.C, cooling, press-forming, and packaging;

step S3: selecting materials, drying, sieving with a 200-mesh sieve, controlling the water content within 4% -5%, and processing and granulating by a wet method through a granulator to obtain the chewing gum.

The children chewing gum for preventing the decayed teeth of the embodiment comprises the following conventional chewing gum formula raw materials in percentage by weight: 15 to 30 percent; the essence comprises the following components in percentage by weight: 0.5-2%; 0.7-1.5% of glycerin by weight; 70 percent of sorbitol 5-15 percent, maltodextrin 3-8 percent and bioactive material-calcium silicon base or calcium phosphorus base material 5-25 percent.

The particle size of the bioactive material of the embodiment is controlled in nanometer and micron scale, and is respectively between 100-500nm and 1-5 um.

The essence of the embodiment is a sweetening agent, and the sweetening agent is one or more of essence, cane sugar, acesulfame potassium and the like; glycerin is used as humectant, which is one or more of glycerin, sorbitol and polyethylene glycol; maltodextrin is used for regulating viscosity.

The children chewing gum for preventing the decayed tooth of the embodiment is used for releasing the bioactive material while chewing the children chewing gum for preventing the decayed tooth, repairing acid-etched enamel under the action of saliva and protecting the loss of tooth mineral substances.

In practice, as shown in fig. 1, the chewing gum prepared by the method of the present invention is a chewing gum, wherein the form of chewing gum is simulated after soaking deciduous teeth in coca-cola for 1 minute, and after 10 minutes, the chewing gum is observed by scanning electron microscope after soaking in simulated oral saliva for 48 hours (a is acid-etched deciduous teeth, and b is deciduous teeth 48 hours after treatment).

As shown in fig. 2, the effect of chewing gum prepared by different bioactive materials on tooth restoration after 48 hours in simulated saliva environment of oral cavity (a is no bioactive material added; b is 5% bioactive material added; c is 15% active material added; d is 20% active material added) is shown.

Figure 3 is an XRD pattern of a simulated masticated enamel surface repaired 48 hours after 5% active material was added to the chewing gum.

According to the mass percentage (wt%)

The following formulations, but not exclusively, were used to formulate the ingredients of the bioactive materials, and the chewing gum was prepared by blending, processing, and preparing.

TABLE 1

Component (%)	Scheme 1	Scheme 2	Scheme 3	Scheme 4
					Chewing gum base	20	20	25	25
Essence	1	1	1.5	1.5
					Glycerol	0.9	0.9	1	1
70% sorbitol	12	12	10	10
					Maltodextrin	4	4	5	5
Bioactive materials	5	10	20	25

As can be seen from Table 1, the above-mentioned 4 experimental formulations exhibited the effect of restoring demineralized teeth with increasing amounts of bioactive materials, and the restoration rate was gradually increased over the same period of time.

In the preparation, the glycerin and the sorbitol mainly play the role of a wetting agent, so that the softness of the chewing gum can be prepared; the added bioactive material not only plays a role of an abrasive, but also has better bioactivity and the function of oral saliva to repair damaged teeth.

The sweetener is essence, and the conventional agent is not limited thereto and can be appropriately formulated.