阅读说明：本技术 一种化学发光仪器 (A kind of chemiluminescence instrument ) 是由 曾爱鸠 吕杨 于 2019-08-27 设计创作，主要内容包括：本发明公开了一种化学发光仪器,包括仪器主体,仪器主体的一侧安装有进样机构、加样机构、反应杯和吸头装载机构、反应杯传送机构以及位于这些机构上方的机械抓手一,反应杯传送机构的一侧安装有试剂盘,试剂盘与反应杯传送机构的上方安装有试剂针机构,反应杯传送机构的另一侧安装有孵育盘、清洗盘和检测器机构,孵育盘和清洗盘的上方安装有机械抓手二,清洗盘的上方还安装有清洗机构。本发明反应杯采用托盘形式装载,避免传统自动装载容易发生的卡杯现象,造成故障频发；吸样采用一次性吸头,完全杜绝交叉污染；清洗机构装载吐液针和吸液针清洗装置,避免吐液针、吸液针长时间不清洗发生结晶,以及避免清洗时发生的交叉污染。(The invention discloses a kind of chemiluminescence instruments, including apparatus subject, the side of apparatus subject is equipped with sample introduction mechanism, sample charging mechanism, reaction cup and suction nozzle loader mechanism, reaction cup transport mechanism and the mechanical gripper one above these mechanisms, the side of reaction cup transport mechanism is equipped with reagent disc, reagent needle mechanism is installed above reagent disc and reaction cup transport mechanism, the other side of reaction cup transport mechanism is equipped with incubation disk, clean disk and detector body, it is incubated for above disk and cleaning disk and mechanical gripper two is installed, wiper mechanism is also equipped with above cleaning disk.Reaction cup of the present invention is loaded using tray form, is avoided tradition from loading incidental card cup phenomenon automatically, is caused Frequent Troubles；It inhales sample and uses disposable tip, prevent cross contamination completely；Wiper mechanism loading spits liquid needle and aspirating needle cleaning device, avoids spitting the raw crystallization of liquid needle, aspirating needle unclear hair washing for a long time, and avoid the cross contamination occurred when cleaning.)

1. a kind of chemiluminescence instrument, including apparatus subject, which is characterized in that the side of the apparatus subject is equipped with sample introduction machine Structure (1), sample charging mechanism (2), reaction cup and suction nozzle loader mechanism (3), reaction cup transport mechanism (5) and be located at these mechanisms on The mechanical gripper one (4) of side, the side of the reaction cup transport mechanism (5) is equipped with reagent disc (7), the reagent disc (7) with Reagent needle mechanism (6), the other side installation of the reaction cup transport mechanism (5) are installed above reaction cup transport mechanism (5) There are incubation disk (8), cleaning disk (10) and detector body (12), is equipped with above the incubation disk (8) and cleaning disk (10) Mechanical gripper two (9) is also equipped with wiper mechanism (11) above the cleaning disk (10).

2. a kind of chemiluminescence instrument according to claim 1, which is characterized in that the reaction cup and suction nozzle loader mechanism (3) it is loading pallet, is provided with several equally distributed hole slots on the loading pallet.

3. a kind of chemiluminescence instrument according to claim 1, which is characterized in that the detector body (12) is independently pacified Loaded on apparatus subject (1).

4. a kind of chemiluminescence instrument according to claim 1, which is characterized in that the wiper mechanism (11) includes spitting liquid Needle, aspirating needle and spit liquid needle and aspirating needle cleaning device.

5. a kind of chemiluminescence instrument according to claim 1, which is characterized in that one end of the sample introduction mechanism (1) is set There are two setting substrate channels (13).

Technical field

The present invention relates to the field of medical instrument technology, more particularly to a kind of chemiluminescence instrument.

Background technique

Chemiluminescence Apparatus is that will there is the immune response of highly sensitive chemical luminescent detecting technology and high specific mutually to tie It closes, the detection and analysis technology for various antigens, haptens, antibody, hormone, enzyme, fatty acid, vitamin and drug etc..Be after Radioimmunology analysis, enzyme are exempted from one grown up after analysis, fluoroimmunoassay and time-resolved fluoroimmunoassay and newest are exempted from Epidemic disease determination techniques.

With the development of medical level, in order to effectively and accurately complete the detection to disease, all kinds of chemiluminescence instruments It arises.With external import chemiluminescence, we has most of market on the market at present, and domestic chemiluminescence is also in primary Developing stage.Each producer's instrument is many kinds of, and feature is different.In order to cater to the luminescence reagent of diversification, accurately and effectively complete Chemiluminescence detection has invented this money chemiluminescence instrument.

Summary of the invention

For overcome the deficiencies in the prior art, the present invention provides a kind of chemiluminescence instrument, can solve institute in background technique The problem of saying.

In order to solve the above technical problems, the invention provides the following technical scheme:

A kind of chemiluminescence instrument, including apparatus subject, the side of the apparatus subject are equipped with sample introduction mechanism, sample-adding machine Structure, reaction cup and suction nozzle loader mechanism, reaction cup transport mechanism and the mechanical gripper one above these mechanisms, it is described anti- It answers the side of glass transport mechanism that reagent disc is installed, reagent needle machine is installed above the reagent disc and reaction cup transport mechanism Structure, the other side of the reaction cup transport mechanism, which is equipped with, is incubated for disk, cleaning disk and detector body, the incubation disk and cleaning Mechanical gripper two is installed above disk, is also equipped with wiper mechanism above the cleaning disk.

As a preferred technical solution of the present invention, the reaction cup and suction nozzle loader mechanism are loading pallet, described Several equally distributed hole slots are provided on loading pallet.

As a preferred technical solution of the present invention, the detector body is independently installed on apparatus subject.

As a preferred technical solution of the present invention, the wiper mechanism is including spitting liquid needle, aspirating needle and spitting liquid needle With aspirating needle cleaning device.

As a preferred technical solution of the present invention, there are two substrate channels for one end setting of the sample introduction mechanism.

Compared with prior art, the attainable beneficial effect of the present invention is:

Reaction cup of the present invention is loaded using tray form, is avoided tradition from loading incidental card cup phenomenon automatically, is caused Frequent Troubles；It inhales sample and uses disposable tip, prevent cross contamination completely；Detection device is loaded using independent single location, is kept away Exempt from that interference effect result occurs；Wiper mechanism loading spits liquid needle and aspirating needle cleaning device, avoids spitting liquid needle, aspirating needle for a long time The raw crystallization of unclear hair washing, and avoid the cross contamination occurred when cleaning；Two substrate channels are arranged in substrate, can be used for enzymatic hair Light and the two kinds of reagent modes that directly shine.

Detailed description of the invention

Fig. 1 is structural schematic diagram of the invention；

Fig. 2 is main view of the invention；

Fig. 3 is side view of the invention；

Wherein: 1, sample introduction mechanism；2, sample charging mechanism；3, reaction cup and suction nozzle loader mechanism；4, mechanical gripper one；5, it reacts Cup transmission device；6, reagent needle mechanism；7, reagent disc；8, it is incubated for disk；9, mechanical gripper two；10, disk is cleaned；11, wiper mechanism； 12, detector body；13, substrate channels.

Specific embodiment

Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings, it should be understood that preferred reality described herein Apply example only for the purpose of illustrating and explaining the present invention and is not intended to limit the present invention.

Please refer to shown in Fig. 1-3, a kind of chemiluminescence instrument, including apparatus subject, the side of apparatus subject be equipped with into Model machine structure 1, sample charging mechanism 2, reaction cup and suction nozzle loader mechanism 3, reaction cup transport mechanism 5 and above these mechanisms Mechanical gripper 1, the side of reaction cup transport mechanism 5 are equipped with reagent disc 7, the top of reagent disc 7 and reaction cup transport mechanism 5 Reagent needle mechanism 6 is installed, the other side of reaction cup transport mechanism 5, which is equipped with, is incubated for disk 8, cleaning disk 10 and detector body 12, the top for being incubated for disk 8 and cleaning disk 10 is equipped with mechanical gripper 29, and the top of cleaning disk 10 is also equipped with wiper mechanism 11.

Wherein, reaction cup and suction nozzle loader mechanism 3 are loading pallet, are provided with several equally distributed holes on loading pallet Slot, reaction cup are loaded using tray form, are avoided tradition from loading incidental card cup phenomenon automatically, are caused Frequent Troubles.

Wherein, detector body 12 is independently installed on apparatus subject 1, and detection device is loaded using independent single location, It avoids that interference effect result occurs.

Wherein, wiper mechanism 11 includes spitting liquid needle, aspirating needle and spitting liquid needle and aspirating needle cleaning device, and wiper mechanism fills Load spits liquid needle and aspirating needle cleaning device, when avoiding spitting the raw crystallization of liquid needle, aspirating needle unclear hair washing for a long time, and avoiding cleaning The cross contamination of generation.

Wherein, there are two substrate channels for setting on the right side of sample introduction mechanism 1, can be compatible with enzymatic simultaneously and shine and directly shine two kinds Reagent mode.When being shone using enzymatic, two substrate channels are set as same substrate, and when use can switch over automatically, After substrate 1 is finished, the use of substrate 2 is automatically switched to.It shines when the direct light-emitting mode of use or with enzymatic while compatibility makes Used time, substrate 1 and substrate 2 are set as two different substrates.

Specifically, the device sample introduction mechanism 1 uses crawler belt sample introduction, stable structure is not easy failure, and position is accurate；

Sample introduction mechanism 1 uses 10 hole location sample rack sample introductions, and sample rack is placed in 1 left and right side of sample introduction mechanism.Sample introduction Mechanism 1 can at most place 9 sample racks, i.e. 90 samples at present.Sample introduction frame carries out front and back transmission using crawler belt, and Y1 crawler belt is first Sample rack is pushed to X1 shaft position, when sample introduction frame upper left corner sensor sensing is to sample rack, X1 spindle motor drives sample rack It is transmitted to sample-adding position.Enter be loaded position before, there are two sensor sensing difference be place test tube there are also noggins.And it sets It is equipped with sample barcode scanner, identifies sample bar code.When sample rack enters sample-adding position, sample charging mechanism 2 works.Inhale sample After the completion, X1 spindle motor continues push that sample rack is turned right, and after the sensor sensing to shelf of the upper right corner, X1 spindle motor stops Origin position is pushed and returns to, Y2 crawler belt will be completed sample-adding sample rack and push forward as far as possible, and that vacates X1 axis direction goes out frame Position.It waits next sample rack to reach the position X1, is recycled with this.

It is sample charging mechanism 2 above sample introduction mechanism 1, sample charging mechanism 2 uses disposable tip, avoids cross contamination from sending out completely It is raw；In the reaction cup and suction nozzle loader mechanism 3 that suction nozzle required for sample charging mechanism 2 is loaded is disposed below.

Sample charging mechanism 2 uses air cannon mouth, installs suction nozzle automatically, then carries out suction sample by air syringe.When inhaling sample Have the function of liquid level automatic sensing and blocking automatic sensing.After the completion of inhaling sample, suction nozzle is removed automatically, carries out next suction sample work.

Reaction cup and suction nozzle loader mechanism 3 place 2 box reaction cups and 2 box suction nozzles.Mechanism can X-direction movement, can a key Load reaction cup and suction nozzle.Reaction cup and suction nozzle number record number by control system, and the position of each position are arranged Number.When mechanical gripper will grab reaction cup, designated position is moved to mechanical gripper and corresponded to by reaction cup and suction nozzle loader mechanism 3 The crawl of reaction cup is completed in position.When sample charging mechanism 2 needs to grab suction nozzle, reaction cup and suction nozzle loader mechanism 3 are by designated suction Head position is moved to below the pipette tips of sample charging mechanism 2, completes the crawl work to suction nozzle.Mechanical gripper takes reaction cup to incubation disk Or after reaction cup transmission device, reaction cup quantity automatically updates number.

Mechanical gripper 1 by reaction cup from reaction cup and suction nozzle loader mechanism 3 on pick-and-place to reaction cup transmission device 5, Then sample-adding and reagent adding work are carried out.

Reaction cup transmission device is arranged 2-5 reaction cup and places hole location, when empty reaction cup needs to add reagent, reaction After empty cup is moved to reagent needle load position by cup transmission device, reagent needle completes sample-adding.When reaction cup needs to add sample, Reaction cup is moved to sample coal addition position by reaction cup transmission device, carries out other behaviour after sample charging mechanism 2 completes sample filling Make.In addition, being additionally provided with automatic mixing function on reaction cup transmission device.It mixes function and guide rail is driven back and forth by eccentric motor High-speed motion, to complete the homogeneous mixing of the sample and reagent in reaction cup.To reaction cup needs enter be incubated for disk or When entering testing agency, reaction cup can equally complete the transmission work of reaction cup, and reaction cup is accurately sent to designated position.

Reagent is placed in reagent disc 7.Reagent bottle has bar code function, and bar code reading scanner is arranged in reagent disc, complete Bar code on pairs of reagent bottle carries out automatic identification.

Reagent needle mechanism 6 carries out reagent adding work, and reagent is added in the reaction cup above reaction cup transmission device 5. Reagent needle set has liquid level inducing function, and sample-adding can be completed under liquid level following depth, avoids taking out of on reagent arm excessive Reagent.After candidate agent needle mechanism 6 completes sample-adding, it is moved to the completion of reagent needle rinse bath and reagent needle outer wall and inner wall is rushed It washes.Reagent inner wall completes cleaning by the internal cleaning solution that injects, and outer wall is rinsed by the water inlet of rinse bath.Reagent Needle mechanism 6 is designed as XY oblique movement, using linear guide control the direction of motion, one end control reagent needle reach reagent disc, one End control reagent needle reaches in reaction cup transport mechanism 5.

After completing sample and reagent pipetting volume, reaction cup is grabbed and is incubated in disk 8 by mechanical gripper 1, is incubated for.It is incubated for Disk uses the thermally conductive direct heating mode of electronics, and heating rate is fast.Disk temperature is entirely incubated for by temperature sensor strict control to exist 37±0.5℃。

After the completion of incubation, mechanical gripper 29 grabs reaction cup into cleaning disk 10, then by turning to wiper mechanism 11 lower sections, wiper mechanism 11 complete the cleaning of reaction cup.When cleaning, hole location rotates the time that each rotation is controlled by system. The process of liquid and imbibition is spat in completion, accomplishes to efficiently separate conjugate and non-bound.Subsequent addition substrate.

Substrate channels 13 can place two kinds of different substrates or same substrate.When system uses enzymatic, setting one Kind substrate, is arranged a substrate dispenser pump and two valves is controlled.After substrate bottle 1 when the left side is finished, system automatically switches To the right substrate bottle 2 carry out using.In use bifurcation pyridine ester or other luminous agent systems, understands and set on lid square on the detector A filling channel is set, for adding substrate 2.Substrate bar code scan is set system by manual scanning rifle by substrate 1 and substrate 2, System completes warning function.

After completing substrate filling, by reaction cup, then the crawl from cleaning disk 10 passes through mechanical gripper 29 to disk 8 is incubated for Reaction cup is grabbed into testing agency 12 and is detected by mechanical gripper 1.After the completion of detection, mechanical gripper 1 is by reaction cup It loses into dustbin, so far entirely luminous testing process is completed.

The present invention has following technical characterstic compared to other similar luminous products:

1, using independent testing agency, hole interdigit cross jamming is avoided.

2, outer wall washing is carried out to cleaning needle using flexible rinse bath, avoids the adverse effects such as cross contamination.

3, reaction cup is loaded using tray form, avoids the adverse effects such as the card cup occurred automatically into cup.

4, using disposable sample-adding suction nozzle, cross contamination occurs when sample being avoided to fill, has prevented cross contamination completely.

5, the different hole location reagent bottles of reagent disc setting 3 hole locations and 5 hole locations etc. load simultaneously, and adapting to different type reagent makes With.

6, two substrate channels are set, and convenient for being suitable for simultaneously, enzymatic shines and the directly luminescent substance such as bifurcation pyridine ester shines Reagent system.It is compatible good.

The implementation of the present invention is not limited to this, and above-described embodiment content according to the invention utilizes the routine of this field Technological know-how and customary means, under the premise of not departing from above-mentioned basic fundamental thought of the invention, preferred embodiment above can be with The modification, replacement or combination of other diversified forms are made, other embodiments obtained all fall within rights protection scope of the present invention Within.