阅读说明：本技术 一种含有辅助降血脂、降血压组合物的低脂肪调制乳粉 (Low-fat modified milk powder containing composition for assisting in reducing blood fat and lowering blood pressure ) 是由 肖东梅 唐诗琦 董单伟 于 2021-07-15 设计创作，主要内容包括：本发明公开了一种含有辅助降血脂、降血压组合物的低脂肪调制乳粉,属于调制乳粉制备领域。本发明解决了现有调制乳粉功能性差,针对性弱的问题。本发明将富含植物甾醇酯的高油乳清粉、水溶性膳食纤维、降脂降压组合物、功能型食品添加剂按照一定比例进行复合搭配,获得一种含有辅助降血脂、降血压组合物的低脂肪调制乳粉。本发明提供的调制乳粉能有效降低总胆固醇与血压值,减少肥胖及高血脂血压人群摄入食物后脂肪堆积的可能,具有辅助药物降低血脂含量、扩张血管、增大渗透压、降低血压值、保护心脑血管健康等优点。(The invention discloses a low-fat modified milk powder containing a composition for assisting in reducing blood fat and blood pressure, and belongs to the field of modified milk powder preparation. The invention solves the problems of poor functionality and weak pertinence of the conventional modified milk powder. The invention relates to a low-fat modified milk powder containing a composition for assisting in reducing blood fat and blood pressure, which is prepared by compounding and matching high-oil emulsion powder rich in phytosterol ester, water-soluble dietary fiber, a composition for reducing blood fat and blood pressure and a functional food additive according to a certain proportion. The modified milk powder provided by the invention can effectively reduce total cholesterol and blood pressure, reduce the possibility of fat accumulation after the obesity and hyperlipidemia and blood pressure people take food, and has the advantages of reducing the blood fat content, expanding blood vessels, increasing osmotic pressure, reducing the blood pressure, protecting the health of heart and cerebral vessels and the like by auxiliary medicines.)

1. A low-fat modified milk powder containing a composition for assisting in reducing blood fat and blood pressure is characterized by comprising the following raw materials in parts by weight: 720-846 parts of blended milk base powder, 150-250 parts of water-soluble dietary fiber, 2.5-3.5 parts of vitamin composition, 19-21 parts of mineral composition, 3-23 parts of lipid and blood pressure reducing composition, 2-10 parts of functional food additive and 120.02 parts of bifidobacterium animalis Bb.

2. The low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure as claimed in claim 1, wherein the milk powder has a protein content of not less than 17.3g/100g, a fat content of not less than 6.0g/100g, a vitamin A content of 300-900 μ g/100g, a vitamin D content of 6.3-12.5 μ g/100g, a vitamin E content of 10-31 mg/100g, a vitamin C content of 30-100 mg/100g, a calcium content of not more than 1200mg/100g, an iron content of 6-20 mg/100g, a zinc content of 3-6 mg/100g, and a selenium content of 14-28 mg/100 g.

3. The low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure as claimed in claim 1, wherein the content of bifidobacterium Bb-12 in the milk powder is not less than 8 x 10⁶CFU/g。

4. The low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure as claimed in claim 1, wherein the modified milk base powder is one or more of skimmed milk powder, concentrated whey protein powder, high oil whey powder rich in phytosterol ester, and desalted whey powder, and is mixed in any ratio.

5. The low-fat modified milk powder with the composition for assisting in reducing blood fat and blood pressure of claim 4, wherein the high oil whey powder rich in phytosterol ester contains 10% phytosterol ester.

6. The low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure according to claim 1, wherein the aqueous dietary fiber is one or more of isomaltooligosaccharide, polydextrose, and inulin, and is mixed in an arbitrary ratio.

7. The low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure according to claim 1, wherein the vitamin composition is one or more of retinyl acetate, cholecalciferol, dl-alpha-tocopherol acetate and sodium L-ascorbate, and is mixed in any ratio.

8. The low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure according to claim 1, wherein the mineral composition is one or more of calcium carbonate, ferrous sulfate, zinc sulfate and sodium selenite, and is mixed in any proportion.

9. The low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure as claimed in claim 1, wherein the composition for reducing blood fat and blood pressure is one or more of earthworm protein, moringa leaf powder, hawthorn fruit powder, kudzu root powder and bamboo leaf flavone which are mixed according to any proportion.

10. The low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure according to claim 1, wherein the functional food additive is one or more of phospholipid and soluble soybean polysaccharide, and is mixed in an arbitrary ratio.

Technical Field

The invention relates to low-fat modified milk powder containing a composition for assisting in reducing blood fat and blood pressure, and belongs to the field of modified milk powder preparation.

Background

Hyperlipidemia is a common cardiovascular disease precursor condition, and refers to the condition that the content of blood lipid in human blood exceeds a normal range due to abnormal fat metabolism or operation, and is manifested by overhigh cholesterol and/or triglyceride or overlow high-density lipoprotein in the blood. With the increase of age, the prevalence rate of hyperlipidemia is remarkably increased, the disease has hidden, progressive and systemic damage to the body, and the reduction of the blood lipid concentration can reduce the occurrence probability of serious diseases such as coronary heart disease, angina pectoris, myocardial infarction and the like. Moreover, hypertension is also a hidden fierce of health of the middle-aged and old people at present, the hypertension is arterial pressure rising, and similar to hyperlipidemia, continuous hypertension can cause heart disease and other cardiovascular and cerebrovascular complications.

At present, common prevention and treatment for hyperlipidemia and hypertension are mainly diet control and drug therapy, and certain side effects are generated on the body for a long time, so that development of a food capable of assisting in relieving and treating hypertension and hyperlipidemia and provision of high-quality protein, dietary calcium and other nutritional ingredients are particularly important.

Disclosure of Invention

The invention aims to provide low-fat modified milk powder containing a composition for assisting in reducing blood fat and blood pressure, which aims to solve the problems of poor functionality and weak pertinence of the conventional modified milk powder, reduce the possibility of fat accumulation after food intake of obese and hyperlipaemia and blood pressure crowds, reduce the blood fat content by an auxiliary medicament, expand blood vessels, increase osmotic pressure, reduce the blood pressure value and protect the health of heart and cerebral vessels.

The technical scheme of the invention is as follows:

a low-fat modified milk powder containing a composition for assisting in reducing blood fat and blood pressure comprises the following raw materials in parts by weight: 720-846 parts of blended milk base powder, 150-250 parts of water-soluble dietary fiber, 2.5-3.5 parts of vitamin composition, 19-21 parts of mineral composition, 3-23 parts of lipid and blood pressure reducing composition, 2-10 parts of functional food additive and 120.02 parts of bifidobacterium animalis Bb.

Further limiting, the milk powder has the protein content of not less than 17.3g/100g, the fat content of more than 6.0g/100g, the vitamin A content of 300-900 mu g/100g, the vitamin D content of 6.3-12.5 mu g/100g, the vitamin E content of 10-31 mg/100g, the vitamin C content of 30-100 mg/100g, the calcium content of not more than 1200mg/100g, the iron content of 6-20 mg/100g, the zinc content of 3-6 mg/100g and the selenium content of 14-28 mg/100 g.

Further limiting, the content of Bifidobacterium animalis Bb-12 in the milk powder is not less than 8 × 10⁶CFU/g。

Further limiting, the blended milk base powder is one or more than two of skimmed milk powder, concentrated whey protein powder, high-oil whey powder rich in phytosterol ester and desalted whey powder which are mixed according to any proportion.

More particularly, the high oil whey powder rich in phytosterol ester contains 10% phytosterol ester.

Further limit, the water-based dietary fiber is one or more of isomaltose hypgather, polydextrose and inulin which are mixed according to any proportion.

Further limit, the vitamin composition is one or more than two of retinyl acetate, cholecalciferol, dl-alpha-tocopherol acetate and L-sodium ascorbate which are mixed according to any proportion.

Further limit, the mineral composition is one or more than two of calcium carbonate, ferrous sulfate, zinc sulfate and sodium selenite which are mixed according to any proportion.

Further, the lipid-lowering and blood pressure-lowering composition is one or more of earthworm protein, moringa oleifera leaf powder, hawthorn fruit powder, kudzu root powder and bamboo leaf flavone which are mixed according to any proportion.

Further, the lipid-lowering and blood pressure-lowering composition is one or more of earthworm protein, moringa oleifera leaf powder, hawthorn fruit powder, kudzu root powder and bamboo leaf flavone which are mixed according to any proportion.

The invention has the following beneficial effects: the invention relates to a low-fat modified milk powder containing auxiliary blood fat and blood pressure reducing compositions, which is prepared by compounding and matching high-oil emulsion powder rich in phytosterol ester, water-soluble dietary fiber, a blood fat and blood pressure reducing composition and a functional food additive according to a certain proportion. The modified milk powder has the following advantages:

(1) the phytosterol ester in the high oil emulsified powder rich in phytosterol ester is easier to be absorbed by human bodies, can effectively balance cholesterol in human bodies, effectively inhibits the human bodies from absorbing low-density lipoprotein from food through the action of occupation and competition, and is known as a 'life key'. The long-term intake of a small amount of phytosterol ester can obviously reduce the blood lipid index and is beneficial to patients with hyperlipidemia, but the phytosterol ester can only be obtained through external intake and cannot be synthesized in human bodies.

(2) The water-soluble dietary fiber adopted by the invention mainly comprises isomaltose hypgather, polydextrose and inulin, and belongs to indigestible carbohydrate. Studies have shown that daily intake of dietary fiber by adults in a certain amount can promote gastrointestinal peristalsis, promote absorption of nutrients, enhance metabolism, and prevent fat deposition. Wherein the polydextrose can also regulate lipid metabolism, inhibit total cholesterol increase, and lower blood lipid index concentration by combining with phytosterol ester. Moreover, the probiotics can accelerate gastrointestinal peristalsis and metabolism, relax bowel, and accelerate decomposition and absorption.

(3) The lipid-lowering and blood pressure-lowering composition adopted by the invention comprises medicine-food homologous substances and new resource food, contains various physiological active factors, can be used as special nutrient substances, can effectively lower the blood fat and blood pressure values of patients with hyperlipidemia and hypertension after being eaten for a long time, and has excellent health-care effect when being matched with phytosterol ester.

(4) The functional food additive adopted by the invention mainly comprises phospholipid and soluble soybean polysaccharide. The food additive contains a plurality of functional materials, and proper addition of the functional materials can enhance the flavor and taste of food, has certain functions of regulating microcirculation and health care, and ensures that functional substances have effective effects.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

The experimental procedures used in the following examples are conventional unless otherwise specified. The materials, reagents, methods and apparatus used, unless otherwise specified, are conventional in the art and are commercially available to those skilled in the art.

Example 1:

the formula of the low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure comprises the following raw materials in parts by weight: 845.48 parts of blended milk base powder, 125 parts of water-soluble dietary fiber, 3.5 parts of vitamin composition, 21 parts of mineral composition, 3 parts of lipid-lowering and pressure-lowering composition, 2 parts of functional food additive and 120.02 parts of animal bifidobacterium Bb.

The names and the addition amounts of the specific components in this example are shown in Table 1.

Example 2:

the formula of the low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure comprises the following raw materials in parts by weight: 814.23 parts of blended milk base powder, 150 parts of water-soluble dietary fiber, 3.25 parts of vitamin composition, 20.5 parts of mineral composition, 8 parts of lipid-lowering and pressure-lowering composition, 4 parts of functional food additive and 120.02 parts of animal bifidobacterium Bb.

The names and the addition amounts of the specific components in this example are shown in Table 1.

Example 3:

the formula of the low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure comprises the following raw materials in parts by weight: 782.98 parts of blended milk base powder, 175 parts of water-soluble dietary fiber, 3 parts of vitamin composition, 20 parts of mineral composition, 13 parts of lipid-lowering and pressure-lowering composition, 6 parts of functional food additive and 120.02 parts of animal bifidobacterium Bb.

The names and the addition amounts of the specific components in this example are shown in Table 1.

Example 4:

the formula of the low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure comprises the following raw materials in parts by weight: 751.73 parts of blended milk base powder, 200 parts of water-soluble dietary fiber, 2.75 parts of vitamin composition, 19.5 parts of mineral composition, 18 parts of lipid-lowering and pressure-lowering composition, 8 parts of functional food additive and 120.02 parts of animal bifidobacterium Bb.

The names and the addition amounts of the specific components in this example are shown in Table 1.

Example 5:

the formula of the low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure comprises the following raw materials in parts by weight: 720.48 parts of blended milk base powder, 225 parts of water-soluble dietary fiber, 2.5 parts of vitamin composition, 19 parts of mineral composition, 23 parts of lipid-lowering and blood-pressure-lowering composition, 10 parts of functional food additive and 120.02 parts of animal bifidobacterium Bb.

The names and the addition amounts of the specific components in this example are shown in Table 1.

Comparative example 1:

the formula of the low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure comprises the following raw materials in parts by weight: 782.98 parts of blended milk base powder, 175 parts of water-soluble dietary fiber, 3 parts of vitamin composition, 20 parts of mineral composition, 13 parts of lipid-lowering and pressure-lowering composition, 6 parts of functional food additive and 120.02 parts of animal bifidobacterium Bb.

Wherein the blended dairy based flour does not contain high oil whey powder rich in phytosterol esters as compared to example 3.

The names and amounts of the specific components in this comparative example are shown in Table 1.

Comparative example 2:

the formula of the low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure comprises the following raw materials in parts by weight: 818.98 parts of blended milk base powder, 145 parts of water-soluble dietary fiber, 3 parts of vitamin composition, 20 parts of mineral composition, 10 parts of lipid-lowering and pressure-lowering composition, 3 parts of functional food additive and 120.02 parts of animal bifidobacterium Bb.

Wherein the water-soluble dietary fiber does not comprise polydextrose compared to example 3; the lipid-lowering and pressure-lowering composition does not contain lipid-lowering substances; the functional food additive does not contain phospholipid.

The names and amounts of the specific components in this comparative example are shown in Table 1.

Comparative example 3:

the formula of the low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure comprises the following raw materials in parts by weight: 795.98 parts of blended milk base powder, 175 parts of water-soluble dietary fiber, 3 parts of vitamin composition, 20 parts of mineral composition, 3 parts of lipid-lowering and pressure-lowering composition, 3 parts of functional food additive and 120.02 parts of bifidobacterium animalis Bb.

Wherein, compared with the embodiment 3, the composition for reducing blood fat and blood pressure does not contain substances for reducing blood pressure; the functional food additive does not contain soluble soybean polysaccharide.

The names and amounts of the specific components in this comparative example are shown in Table 1.

Comparative example 4:

the formula of the low-fat modified milk powder containing the composition for assisting in reducing blood fat and blood pressure comprises the following raw materials in parts by weight: 831.98 parts of blended milk base powder, 145 parts of water-soluble dietary fiber, 3 parts of vitamin composition, 20 parts of mineral composition, 0 part of lipid-lowering and pressure-lowering composition, 0 part of functional food additive and 120.02 parts of animal bifidobacterium Bb. Compared with example 3, no effective substance was added.

The names and amounts of the specific components in this comparative example are shown in Table 1.

TABLE 1 ingredient ratios of raw and auxiliary materials in examples 1 to 5 and comparative examples 1 to 4

The high oil emulsion powder rich in phytosterol ester is purchased from Niilongjiang spectra Huawei dairy group Limited company, patent application No. 202110600621.3, and the high oil emulsion powder rich in phytosterol ester not only embeds phytosterol ester capable of reducing cholesterol, but also comprises milk fat globule membrane protein capable of improving memory and cognitive ability, nourishes cranial nerves and plays a double role in guaranteeing body health. The amount of phytosterol ester enriched high oil whey powder added to the blended dairy based powder was adjusted in examples 1-5 and comparative examples 1-4 to determine the effect of phytosterol ester content on lipid related indicators such as triglycerides, total cholesterol, low density lipoprotein cholesterol, etc., and the phytosterol ester content in each of the examples and comparative examples is shown in table 2:

TABLE 2 phytosterol ester content Table

Measurement and characterization:

(first) evaluation of nutrient composition

Physical and chemical indexes such as nutritional components were measured for the low-fat modified milk powders containing the auxiliary hypolipidemic and hypotensive compositions of examples 1 to 5 and comparative examples 1 to 4.

The following experiments were repeated 3 times to ensure the accuracy of the experimental values, the data are expressed as mean ± standard deviation, and the determination results are shown in table 3:

TABLE 3 nutrient composition Table

It can be seen from table 3 that the fat content in examples 1 to 4 and comparative examples 1 to 4 is less than or equal to 3g/100g, and the main source of fat is provided by the high oil emulsion powder rich in phytosterol ester, and the low fat modified milk powder can be determined according to the regulations of the food label in GB 28050-. Other nutrient components such as protein, dietary fiber and the like are mixed by reasonable distribution, and the contents of milk base powder, vitamins and mineral substances are made to reach the recommended intake of each nutrient in Chinese resident dietary guidelines and the use standards of GB 14880-2012 food safety national standard food nutrition enhancers. From table 3, it can also be seen that the adjustment of the milk-based powder ratio has a greater effect on carbohydrates, vitamin D and vitamin E, and can significantly reduce or increase their content, affecting the intake value.

(II) evaluation of low-fat modified milk powder of composition for assisting in reducing blood fat and lowering blood pressure on effects of assisting in reducing blood fat and lowering blood pressure

The low-fat modified milk powder of the auxiliary blood fat and blood pressure reducing compositions of example 3 and comparative examples 1 to 4 was subjected to auxiliary blood fat and blood pressure reduction trial tests to determine the influence of the addition of phytosterol ester, polydextrose, the blood fat and blood pressure reducing compositions and functional food additives on triglyceride, total cholesterol, low-density lipoprotein cholesterol and blood pressure values.

The test method comprises the following steps: in the experiment, 120 middle-aged and old-aged subjects of 30-60 years old are recruited, and each half of the subjects are required to be male and female, the subjects for testing blood fat are the population with high blood fat or the population with slight high blood fat within the range, and the subjects for testing blood fat are the patients with hypertension and participate in the experiment voluntarily; before drinking, the variety of antihypertensive drugs is not required to be changed, and the requirements for taking the drugs are halved, the diet is light and the nutrition is balanced. The subjects were divided into 60 persons each in the blood lipid group and the blood pressure group, and randomly divided into 5 groups in 2 groups, each half of each group was male and female, and drunk for 60 days, and 32g of the low fat blended milk powder of the composition for assisting the blood lipid and blood pressure reduction was mixed with 180mL of warm water before breakfast and dinner every day, and triglyceride, total cholesterol, low density lipoprotein cholesterol and blood pressure values were measured every 30 days. Wherein, triglyceride, total cholesterol and low density lipoprotein cholesterol are detected professionally in a designated hospital by adopting a blood measuring method; the blood pressure value is measured by a sphygmomanometer to determine blood lipid and blood pressure variation parameters. The changes in the detailed triglyceride, total cholesterol, low density lipoprotein cholesterol and blood pressure values are shown in Table 4.

TABLE 4 Table for changes in blood lipid and blood pressure values after drinking

Note: different superscript letters indicate significant differences in triglyceride, total cholesterol, LDL-cholesterol and blood pressure values (p < 0.05) for different drinking times of the same group

It can be seen from table 4 that the addition of phytosterol esters, polydextrose, lipid-lowering and blood-pressure-lowering compositions and functional food additives has a significant effect on triglycerides, total cholesterol, low density lipoprotein cholesterol and blood pressure values. In contrast to example 3, no phytosterol ester was added to comparative example 1, no polydextrose and lipid-lowering composition was added to comparative example 2, no pressure-lowering composition was added to comparative example 3, and no effective functional substance was added to comparative example 4. Triglyceride, total cholesterol and low-density lipoprotein cholesterol in the detection indexes can reflect the change of blood fat, and the addition of the phytosterol ester in the example 3, the comparative example 2 and the comparative example 3 can obviously reduce the content of the total cholesterol (p is less than 0.05) after 60 days of drinking test, wherein the reduction rates are respectively 15.3%, 10.3% and 13.2%; in contrast, in comparative example 2, the extent of reduction was reduced without the addition of the lipid-lowering composition; in comparative example 1, the triglyceride content and the total cholesterol content of the composition only added with the fat-reducing and blood-pressure-reducing are respectively reduced by 10.7 percent and 5.8 percent, and the reduction rate is reduced compared with that of example 3; the low-density lipoprotein cholesterol can visually reflect the influence of hyperlipidemia on human bodies, the low-fat modified milk powder of the composition for assisting in reducing blood fat and blood pressure can effectively reduce the content of the low-density lipoprotein cholesterol by drinking, and the comparative example 4 has little influence or even has rising tendency on the change of the low-density lipoprotein cholesterol without adding effective functional substances. From the above and tables, it is known that the phytosterol ester, polydextrose and lipid-lowering and blood-pressure-lowering composition produce synergistic lipid-lowering effect, and adjuvant drug therapy can effectively reduce the contents of triglyceride, total cholesterol and low-density lipoprotein cholesterol. Similar to blood fat index, the blood pressure value also changes the same, namely the effective functional substance has effective effect on reducing the blood pressure value and has the effect of gaining together with the lipid-lowering substance.