阅读说明：本技术 区域选择性取代的纤维素酯 (The cellulose esters that regioselectivity replaces ) 是由 凯西·林恩·埃尔金斯 罗伯特·杰克·夏普 王斌 于 2018-03-28 设计创作，主要内容包括：本申请公开了区域选择性取代的纤维素酯、由该区域选择性取代的纤维素酯制成的膜及其制造方法。该区域选择性取代的纤维素酯是使用三氟乙酸酐和纤维素与不同的酰基给体或者酰基给体前体来合成的。(Film and its manufacturing method made of the cellulose esters that replaces this application discloses regioselectivity, the cellulose esters replaced the regioselectivity.The cellulose esters that the regioselectivity replaces is synthesized using trifluoroacetic anhydride and cellulose from different acyl donors or acyl donor precursor.)

1. the cellulose esters that a kind of regioselectivity replaces, it includes:

(i) multiple R¹- CO- substituent group；

(ii) multiple R⁴- CO- substituent group；

(iii) multiple hydroxyl substituents,

Wherein R¹The degree of substitution (" C2DS of-CO- on the position C2_R1") in the range of about 1.0 about 0.2-,

Wherein R¹The degree of substitution (" C3DS of-CO- on the position C3_R1") in the range of about 1.0 about 0.2-,

Wherein R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") in the range of about 0.5 about 0-,

Wherein R⁴The degree of substitution (" C6DS of-CO- on the position C6_R4") in the range of about 1.0 about 0.1-,

Wherein the degree of substitution of hydroxyl is in the range of about 2.6 about 0-,

Wherein R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) alkenyl, (C_3-7) naphthenic base；(C_6-20) aryl, wherein The aryl is unsubstituted or with 1-6 R²What group replaced；Or 5-20 unit's heteroaryl, contain independently selected from 1-3 hetero atom of oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R³What group replaced,

Wherein R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) ring Alkyl, (C_6-10) aryl or nitro,

Wherein R³Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) ring Alkyl, (C_6-10) aryl or nitro；

Wherein R⁴It is selected from: (C_1-20) alkyl；Halogenated (C_1-5) alkyl；(C_2-20) alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, wherein The aryl is unsubstituted or with 1-6 R⁵What group replaced；Alternatively, monocycle or bicyclic heteroaryl, contain independence Ground is selected from 1-3 hetero atom of oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R⁶What group replaced,

R⁵Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) cycloalkanes Base, (C_6-10) aryl or nitro, and

R⁶Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) cycloalkanes Base, (C_6-10) aryl or nitro.

2. the cellulose esters that regioselectivity according to claim 1 replaces, wherein R¹- CO- be selected from acetyl group, propiono, Bytyry, benzoyl, naphthoyl, 3,4,5- trimethoxybenzoy, xenyl-CO-, benzoyl-benzoyl-or Person's benzothiophene-CO-；And wherein R⁴- CO- is selected from acetyl group, propiono, bytyry, benzoyl, acetyl group, naphthalene formyl Base, 3,4,5- trimethoxybenzoy, xenyl-CO-, benzoyl-benzoyl-or benzothiophene-CO-.

3. the cellulose esters that regioselectivity according to claim 1 replaces, wherein C6DS_R1-CO-Less than 0.1.

4. the cellulose esters that regioselectivity according to claim 1 replaces, wherein R¹- CO- is propiono.

5. the cellulose esters that regioselectivity according to claim 4 replaces, wherein the degree of substitution of propiono is about 1.0- about 1.4, the C2 degree of substitution of propiono are 0.6-0.9, and the C3 degree of substitution of propiono is about 0.3- about 0.5.

6. the cellulose esters that regioselectivity according to claim 5 replaces, wherein substitution of the propiono on the position C6 Degree is less than 0.05.

7. the cellulose esters that the regioselectivity according to any one of claim 4-6 replaces, wherein R⁴- CO- is (C_6-20) Aryl-CO-.

8. the cellulose esters that the regioselectivity according to any one of claim 4-6 replaces, wherein R⁴- CO- is pivaloyl Base and (C_6-20) aryl-CO- combination.

9. the cellulose esters that regioselectivity according to claim 8 replaces, wherein (C_6-20) aryl-CO- be selected from benzoyl Base and naphthoyl.

10. the cellulose esters that according to any one of claim 8-9 regioselectivity replaces, wherein valeryl takes Dai Du is 0.6-0.9；And (C_6-20) degree of substitution of aryl-CO- is 0.2-0.5.

11. the cellulose esters that regioselectivity according to claim 1 replaces, wherein R¹- CO- be comprising benzoyl and The combination of naphthoyl.

12. the cellulose esters that regioselectivity according to claim 11 replaces, wherein R⁴- CO- is (C_1-6) alkyl-CO-.

13. the cellulose esters that regioselectivity according to claim 12 replaces, wherein the degree of substitution of benzoyl is big About 0.2- about 1.2, wherein the degree of substitution of naphthoyl is about 0.8- about 1.8, and wherein (C_1-6) alkyl-CO- takes Dai Du is less than 0.5.

14. the cellulose esters that regioselectivity according to claim 13 replaces, wherein R⁴- CO- is propiono.

15. the cellulose esters that regioselectivity according to claim 1 replaces, wherein R¹- CO- is propiono and benzoyl The combination of base.

16. the cellulose esters that regioselectivity according to claim 15 replaces, wherein R⁴- CO- is propiono and benzoyl The combination of base.

17. the cellulose esters that regioselectivity according to claim 16 replaces, wherein total C2 of benzoyl and C3 degree of substitution is 0.1-0.6, and wherein total C2 and C3 degree of substitution of propiono is 0.5-1.4, and wherein the C6 of benzoyl takes Dai Du is 0-0.8, and wherein the C6 degree of substitution of propiono is 0-1.0.

18. the cellulose esters that regioselectivity according to claim 17 replaces, wherein the C6 degree of substitution of benzoyl is 0.1-0.2, and wherein the C6 degree of substitution of propiono is 0.4-0.8.

19. the cellulose esters that regioselectivity according to claim 1 replaces, wherein weight average molecular weight (" M_w") about In the range of 50000Da- about 500000Da.

Invention field

The present invention relates to cellulose chemistry, cellulose ester composition, manufacture cellulose esters method and by cellulose esters system At film field.

Background of invention

Cellulose is the polymer of the β -1,4- connection of anhydroglucose.Cellulose be usually high molecular weight, polydispersity it is poly- Close object, not soluble in water and nearly all common organic solvent.In timber or cotton production (such as outer cover or fabric) It the use of unmodified cellulose is well known.Unmodified cellulose is also used to various other applications, usually as film (such as glass Glass paper), as fiber (such as viscose artificial silk), or as powder, (such as microcrystalline cellulose is used for pharmacy and answers With).Modified cellulose --- such as cellulose esters is also widely used in extensive a variety of business applications.Prog.Polym.Sci.2001,26,1605-1688.Cellulose esters is usually through the following steps that preparation: first by cellulose It is converted to cellulose triester, is then hydrolyzed cellulose triester in acidic aqueous media to desired degree of substitution.Triacetic acid is fine The hydrolysis of dimension element under these conditions produces random copolymer, and the copolymer can be by 8 kinds of different monomer compositions, this takes Certainly in final degree of substitution.Macromolecules 1991,24,3050。

This application describes the cellulose esters that new regioselectivity replaces, the cellulose esters is through the following steps that preparation : cellulose is handled in trifluoroacetic acid with trifluoroacetic anhydride first, and acyl donor or acyl donor precursor is then added.

Summary of the invention

This application discloses the cellulose esters that a kind of regioselectivity replaces, which includes:

(i) multiple R¹- CO- substituent group；With

(ii) multiple hydroxyl substituents,

Wherein R¹The degree of substitution (" C2DS of-CO- on the position C2_R1") in the range of about 1.0 about 0.2-,

Wherein R¹The degree of substitution (" C3DS of-CO- on the position C3_R1") in the range of about 1.0 about 0.2-,

Wherein R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") in the range of about 0.5 about 0-,

Wherein the degree of substitution of hydroxyl is in the range of about 2.6 about 0-, and

Wherein R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, Wherein the aryl is unsubstituted or with 1-6 R²What group replaced；Alternatively, 5-20 unit's heteroaryl, contains independently The 1-3 hetero atom selected from oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R³What group replaced,

R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) Naphthenic base, (C_6-10) aryl or nitro, and

R³Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) Naphthenic base, (C_6-10) aryl or nitro.

Disclosed herein as well is the cellulose esters that a kind of regioselectivity replaces, which includes:

(i) multiple R¹- CO- substituent group；

(ii) multiple R⁴- CO- substituent group；

(iii) multiple hydroxyl substituents,

Wherein R¹The degree of substitution (" C2DS of-CO- on the position C2_R1") in the range of about 1.0 about 0.2-,

Wherein R¹The degree of substitution (" C3DS of-CO- on the position C3_R1") in the range of about 1.0 about 0.2-,

Wherein R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") in the range of about 0.5 about 0-,

Wherein R⁴The degree of substitution (" C6DS of-CO- on the position C6_R4") in the range of about 1.0 about 0.1-,

Wherein the degree of substitution of hydroxyl is in the range of about 2.6 about 0-,

Wherein R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) alkenyl, (C_3-7) naphthenic base；(C_6-20) aryl, Wherein the aryl is unsubstituted or with 1-6 R²What group replaced；Alternatively, 5-20 unit's heteroaryl, contains independently The 1-3 hetero atom selected from oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R³What group replaced,

Wherein R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro,

Wherein R³Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro；

Wherein R⁴It is selected from: (C_1-20) alkyl；Halogenated (C_1-5) alkyl；(C_2-20) alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, Wherein the aryl is unsubstituted or with 1-6 R⁵What group replaced；Alternatively, monocycle or bicyclic heteroaryl, contain The 1-3 hetero atom independently selected from oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R⁶Group takes Generation,

R⁵Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) Naphthenic base, (C_6-10) aryl or nitro, and

R⁶Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) Naphthenic base, (C_6-10) aryl or nitro.

Film made of the cellulose esters replaced regioselectivity disclosed herein is also disclosed in the application.The application is also disclosed The method for preparing the cellulose esters that regioselectivity disclosed herein replaces.

Specific embodiment

It in this specification and follows in claim, refers to many terms, the meaning for having following should be defined as.

Singular "/kind (a/an) " and " should/described " include plural object, are clearly referred to unless the context otherwise Show.

It is given number that value, which can be expressed as " about/substantially ",.Similarly, range can be expressed as herein from " about " one A occurrence and/or arrive " about " or another occurrence.It when such a range is expressed, on the other hand include specific from one It is worth and/or arrives another occurrence.Similarly, when value is expressed as approximation using antecedent " about ", it will be understood that occurrence It is formed on the other hand.

Optical film quantifies generally according to birefringence, then birefringence is related to refractive index n.In general, polymer Refractive index usually can be in the range of 1.4-1.8, and cellulose esters can be about 1.46-1.50.Refractive index is higher, and light wave passes It broadcasts slower across given material.

For non-oriented isotropic material, refractive index will be it is identical, but regardless of the polarization state of the light wave of entrance.In Material become orientation or when anisotropy, refractive index becomes related with material direction.For the purpose of the present invention, there is n_x、n_yAnd n_zThe important three kind refractive index indicated corresponds respectively to longitudinal direction (machine direction, " MD "), transverse direction (transverse direction, " TD ") and thickness direction.When material becomes more anisotropy (such as passing through stretching), Difference between any two refractive index will increase.This difference is referred to as " birefringence ".Because in the presence of material to be selected Many combinations in direction, therefore accordingly there is different birefringence values.Most common two kinds, i.e., planar birefringence rate (or " in plane " birefringence) Δ_eWith thickness birefringence (or " outside plane " birefringence) Δ_thIs defined as:

(1a) Δ_e=n_x–n_y

(1b) Δ_th=n_z–(n_x+n_y)/2

Birefringence Δ_eIt is the measurement being orientated in the opposite plane between the direction MD and TD, and is nondimensional.Phase Anti- Δ_thIt gives for mean level of the sea orientation, the measurement of the orientation of thickness direction.

Another term for being frequently used for optical film is optical delay R.R be simply discussed film birefringence multiplied by Thickness d.Therefore,

(2a) R_e=Δ_eD=(n_x–n_y)d

(2b) R_th=Δ_thD=[n_z–(n_x+n_y)/2]d

Delay is the direct measurement that the relative phase between two orthogonal light waves moves, and is usually with unit nanometer (nm) To describe.It should be noted that R_thBe defined in some authors and be different, in particular to symbol (+/-) when, this depends on R_th How to calculate.

Material it is known that birefringent/delay behavior about them and change.Such as most of material is when stretched by table Reveal along the higher refractive index of draw direction and perpendicular to the lower refractive index of stretching.This is because of in molecular water It is higher generally along the axis refractive index of polymer chain and lower perpendicular to the chain refractive index on flat.These materials are commonly referred to as Make " positive birefringence ", and represent most of conventional polymer, including presently commercially available cellulose esters.It should be noted that such as Below, by description, positive birefringence material can be used for manufacturing positive or negative birefringent film or wave plate for we.

In order to avoid obscuring, it is poly- that the birefringent behavior of polymer molecule itself, which will be referred to as " intrinsic birefringent (rate) ", Close a kind of characteristic of object.For materials optical viewpoint, intrinsic birefringence is the measurement of such birefringence: it will occur When material is completely stretched and all chain is ideally aligned in one direction, (for most of polymer, this is one A theoretical limit, because they are never perfectly aligned).For objects of the invention, it is also provided given polymer for The measurement of the sensibility of the chain orientation of specified rate.For example, the high sample of intrinsic birefringence will be shown in film forming process The bigger birefringence of the sample lower than intrinsic birefringence, even if the relative stress level in film is roughly the same.

Polymer can have positive and negative or zero intrinsic birefringence.Bear intrinsic birefringent polymer show perpendicular to Higher refractive index on draw direction (relative to parallel direction).Certain phenylethylenes and acrylic compounds, which can have, bears intrinsic pair Refraction behavior, this is attributed to their rather huge side groups.Depending on composition, some cellulose esters with aromatic ring structure can also To show to bear intrinsic birefringence.On the contrary, zero intrinsic birefringence is a kind of special circumstances, represents and do not showed when stretching Birefringence and therefore the material with zero intrinsic birefringence out.Such material can be for certain optical applications Preferably, because they can be molded, be stretched or be pressurized power in process, prolong without showing any optics Late or distort.

Practical compensation film for LCD can take various forms, including biaxial film (wherein all three refractive index not Together, and there is two optical axises) and uniaxial film (have only one optical axis, wherein two in three refractive index are identical ).There is also other kinds of compensation films, and wherein optical axis distorts or tilt through the thickness of film (such as plate-like film), still These are usually not too important.In general, the type for the compensation film that can be manufactured by polymer birefringent characteristic (that is, just, Negative or zero intrinsic birefringence) limitation.Symbol (such as+A or A+) can be put before or after the type of film.

Several examples are as described below.

In the case where uniaxial film, there is following refractive index:

(3a) n_x>n_y=n_z"+A " optical film

So that the film is referred to as "+A " optical film.In such film, the direction x (longitudinal direction) of film has high refractive index, And the direction y and thickness direction are roughly the same on the order of magnitude (and lower than n_x).Such film is also referred to as positive uniaxial Crystal structure has the optical axis along the direction x.Such film can be used such as film stretching device be uniaxially stretched it is just intrinsic birefringent Material manufactures.

On the contrary, "-A " uniaxial film is defined as:

(3b) n_x<n_y=n_z"-A " optical film

Wherein x-axis refractive index is lower than other directions (refractive index in other directions is roughly equal).A kind of manufacture-A light The method for learning film is to stretch to bear intrinsic birefringent polymer, or alternatively, by that will bear (intrinsic) birefringence liquid crystal polymer It applies to a surface, so that molecule is aligned (such as using oriented layer in following etching) in a preferred direction.

In terms of delay, the R of " ± A " optical film_eAnd R_thBetween have the following relationship shown in (3c):

(3c) R_Th=–R_e/ 2 " ± A " optical films

Another kind of uniaxial optical film is C optical film, is also possible to "+C " or "-C ".C optical film and A optical film it Between be not both: in C optical film, unique refractive index (or optical axis) is in a thickness direction, and in the plane of film On the contrary.Therefore,

(4a) n_z>n_y=n_x"+C " optical film

(4b) n_z<n_y=n_x"-C " optical film

By the stress formed in the solvent cast using film, C optical film can be produced.Tensile stress is generally produced in film In plane, this is attributed to the constraint that casting belt is applied, and it is biaxial stretch-formed that essence is also etc..These tend to put down chain in film It is aligned in face, birefringent material intrinsic for positive and negative forms respectively-C or+C film.Because of many used in the display Cellulose ester membrane is solvent cast, and many is substantially positive birefringence, it is therefore apparent that the cellulose of solvent cast Ester mostly just generation-C optical film.These films can also be uniaxially stretched to generate+A optical film (it is assumed that initial curtain coating postpones It is low-down).

Other than uniaxial optical film, Biaxially oriented film can also be used.Biaxial film quantifies in many ways, including 3 refractive index n being simply listed on principal direction (along the direction of these main shafts)_x、n_yAnd n_z.In general, n_x≠n_y≠n_z。

A kind of specific Biaxially oriented film compensates the polarizing film or plane of a pair of cross with unique optical characteristics Convert the light leakage of (in-plane switching, " IPS ") mode LCD.The parameter Nz of optical film is about In the range of 0.4- about 0.9, or it is equal to about 0.5, wherein Nz is defined as:

(5) Nz=(n_x-n_z)/(n_x-n_y)

This parameter gives relative to effective out-of-plane birefringence birefringent in plane.When being used as a pair of cross When the compensation film of polarizing film, Nz can choose to be about 0.5.When Nz is about 0.5, the corresponding slow R of planar epitaxial_thIt is equal to About 0.0nm.

In order to show the compensation effect of optical film, by the way that there is compensation film below computer Simulation calculation and do not have compensation The light transmission or light of a pair of cross polarizing film of film leak.

" degree of substitution " indicates the average of the substituent group of each glucose anhydride monomer of cellulose esters.Degree of substitution can be adapted for The substituent group being attached on glucose anhydride monomer, such as acyl group.Degree of substitution also also refers to the free hydroxyl on glucose anhydride monomer Number.Degree of substitution can explicitly point out the position on glucose anhydride monomer.For example, degree of substitution can be applied to glucose anhydride monomer The position C2, C3 or C6 (for example, C2DS, C3DS, C6DS):

Alternatively, position degree of substitution can by before the term " degree of substitution " indicating positions express (for example, C2 replaces Degree, or total C2 and C3 degree of substitution).

" degree of polymerization " indicates to constitute the number of the glucose unit of a polymer molecule.

The cellulose esters that regioselectivity suitable for manufacturing optical film replaces may include multiple alkyl-acyl substituent groups With multiple aryl-acyl substituents.As used herein, term " acyl substituent " should indicate the structure for having following Substituent group:

Or R-CO-.

Such acyl group in cellulose esters is usually bonded to the pyranose of cellulose via ester bond (that is, passing through oxygen atom) On ring.

As used herein, term " alkyl-acyl " should indicate that wherein " R " is the acyl substituent of alkyl.Usually The carbon unit of alkyl is to be included；For example, (C_1-6) alkyl-acyl.The example of alkyl-acyl include acetyl group, propiono, Bytyry etc..

As used herein, term " alkyl " should indicate hydrocarbon substituent.Alkyl suitable for this can be straight chain, branch Change perhaps cyclic and can be saturation or it is unsaturated.Carbon unit in alkyl, which is often, includes；For example, (C_1-6) alkyl.Alkyl suitable for this includes any (C_1-20)、(C_1-12)、(C_1-5) or (C_1-3) alkyl.In different implementation In example, alkyl can be C_1-5Straight chained alkyl.In further embodiments, alkyl can be C_1-3Straight chained alkyl.Suitable alkyl Specific example include but is not limited to methyl, ethyl, n-propyl, isopropyl, normal-butyl, isobutyl group, sec-butyl, tert-butyl, penta Base, hexyl, octyl, decyl, dodecyl, cyclopenta and cyclohexyl.

Acylating agent can be any acylating agent known in the art that cellulose esters is produced for acylated cellulose.At this In one embodiment of invention, acylating agent is one or more C₁-C₂₀Straight chain or branched chain alkyl or aryl carboxylic acid acid anhydride, carboxylic acid halogen Compound, diketene or acetoacetic ester.The example of carboxylic acid anhydrides includes but is not limited to: acetic anhydride, propionic andydride, butyric anhydride, isobutyl Acid anhydrides, caproic anhydride, 2 ethyl hexanoic acid acid anhydride, nonanoic anhydride, lauric anhydride, palmitic anhydride, stearic anhydride, benzoyl oxide, takes valeric anhydride Benzoyl oxide, phthalic anhydride and the isophthalic anhydride in generation.The example of carboxylic acid halide includes but is not limited to: acetyl halide, Propionyl halogen, butyryl halogen, hexanoyl halogen, 2- ethyl hexyl carboxylic acid halides, laurel carboxylic acid halides, palm carboxylic acid halides, benzoyl halogen, substituted benzoyl halogen and Stearic carboxylic acid halides.The example of acetoacetic ester includes but is not limited to: methyl acetoacetate, ethyl acetoacetate, propyl acetoacetate, Butyl-acetoacetate and tert-butyl acetoacetate.In one embodiment of this invention, acylating agent is selected from the group constituted below At least one C₂-C₉Straight chain or branched alkane yl carboxylic acid acid anhydride: acetic anhydride, propionic andydride, butyric anhydride, 2 ethyl hexanoic acid acid anhydride, nonanoic anhydride and Stearic anhydride.The acylating agent can be added after cellulose has been dissolved in alkyl phosphoric acid tetra-allkylammonium.If necessary Words, acylating agent can be added in alkyl phosphoric acid tetra-allkylammonium before cellulose dissolution is in alkyl phosphoric acid tetra-allkylammonium.In In another embodiment, alkyl phosphoric acid tetra-allkylammonium and acylating agent can be added to simultaneously cellulose to produce cellulose solution.

" halogenated alkyl " indicates the alkyl substituent that wherein at least one hydrogen is replaced by halogen group.Carbon in halogenated alkyl Unit is often included, for example, halogenated (C_1-6) alkyl.Halogenated alkyl can be straight chain or branching.Halogenated alkyl it is non- Limited example includes: chloromethyl, trifluoromethyl, dibromoethyl etc..

" alkenyl " indicates the alkyl that at least two carbon units contain at least one double bond.Carbon unit in alkenyl is often quilt Including；For example, (C_2-6) alkenyl.Alkenyl can be straight chain or branching.The not limiting example of alkenyl includes: vinyl, alkene Propyl, 1- cyclobutenyl etc..

" naphthenic base " indicates the alkyl of the cyclization at least three carbon unit.Carbon unit in naphthenic base often included； For example, (C_3-8) naphthenic base.The not limiting example of naphthenic base includes: cyclopropyl, cyclobutyl, cyclohexyl, suberyl etc..

" aryl " indicates aromatic carbocyclic radical.Aryl can be monocycle or polycyclic.If in polycyclic ring system One ring is aryl, then the polycyclic ring system is considered as aryl.In other words, in polycyclic aryl, not all carbocyclic ring must It must all be aromatics.Carbon unit in aryl often included；For example, (C_6-20) aryl.The not limiting example of aryl includes: Phenyl, naphthalene, 1,2,3,4-tetralin base etc..

" heteroaryl " indicates such aryl, and wherein at least one carbon unit in aromatic ring is by hetero atom (such as O, N and S) Replace.Heteroaryl ring can be monocycle or polycyclic.In general, the unit for constituting heteroaryl ring system is to be included；For example, 5-20 ring system.5 unit's heteroaryls indicate the ring system that there are 5 atoms to form heteroaryl ring.The non-limiting example of heteroaryl Son includes: pyridyl group, quinolyl, pyrimidine radicals, thienyl etc..

" alkoxy " indicates that alkyl-O- or alkyl terminate to oxygroup.Carbon unit is commonly included；Such as (C_1-6) alcoxyl Base.The not limiting example of alkoxy includes methoxyl group, ethyoxyl, propoxyl group etc..

" halogenated alkoxy " indicates that such alkoxy, wherein at least one hydrogen are optionally substituted by halogen.Carbon unit is usually wrapped It includes；For example, halogenated (C_1-6) alkoxy.The not limiting example of halogenated alkoxy includes: trifluoromethoxy, bromo methoxyl group, 1- Bromo- ethyoxyl etc..

" halogen (generation) " indicates halogen, such as fluorine (generation), chlorine (generation), bromine (generation) or iodine (generation).

" reversion A film " is the film for meeting following condition: in the plane measured at 589nm delay about 100nm- about In the range of 300nm, R_e450/R_e550 less than 1, R_e650/R_e550 are greater than 1, wherein R_e450、R_e550 and R_e650 be respectively Length of delay in the plane of the film measured under wavelength 450nm, 550nm and 650nm.

" reversion NRZ film " is the film for meeting following condition: postponing (" R in the plane measured at 589nm_e") about In the range of 100nm- about 300nm, the slow (" R of planar epitaxial_th") in the range of about -50nm arrives about 0nm, R_e450/ R_e550 less than 1, R_e650/R_e550 are greater than 1, wherein R_e450、R_e550 and R_e650 be respectively in wavelength 450nm, 550nm and Length of delay in the plane of the film measured under 650nm.

" NRZ film " is the film for meeting following condition: using N_ZValue, is n_z=(n_x-n_z)/(n_x-n_y)=0.5.Or make Use R_thValue, R_th=[n_z-(n_x+n_y)/2] * d=0.Here, n_x、n_yAnd n_zIt is refractive index of the film in the direction x, y and z, d respectively It is film thickness.

As used herein, term " being selected from " with "and" or "or" when being used together with following meaning: choosing Indicate that the variable can be individual A, individual B or individual C from the variable of A, B and C.Variables A, B or C indicate the change Amount may is that individual A, individual B, the combination of individual C, A and B, the combination of B and C, the combination of A and C or A, B and C Combination.

Cellulose esters prepared by the method for the present invention can be used for a variety of applications.It will be appreciated by those skilled in the art that specific Application will depend on the concrete type of cellulose esters, type, DS, MW as factor such as acyl substituent, and fiber The type of plain ester copolymer significantly affects the physical characteristic of cellulose esters.Prog.Polym.Sci.2001,26,1605-1688。

In another embodiment of the invention, cellulose esters is used for coating application.The example of coating application includes but unlimited In: car paint, wood coating, plastic paint or metallic paint.The example of preferred cellulose esters for coating application It include: cellulose acetate, cellulose propionate, cellulose butyrate, cellulose-acetate propionate, cellulose acetate-butyrate or it is mixed It closes.

In another embodiment of the invention, cellulose esters uses in the application for the solvent cast for being related to film.These are answered Example includes light-sensitive surface and protective film and compensation film for liquid crystal display.For the preferred of solvent cast film application The example of cellulose esters include: cellulose triacetate, cellulose acetate, cellulose propionate and cellulose-acetate propionate.

In another embodiment of the invention, cellulose esters of the invention can make in the application for the solvent cast for being related to film With.The example of such application includes light-sensitive surface, protective film and compensation film, is used for LCD.Suitable for solvent cast film application The example of cellulose esters includes but is not limited to: cellulose triacetate, cellulose acetate, cellulose propionate and cellulose acetate propionate Element.

In one embodiment of this invention, the film comprising cellulose esters of the invention is produced, and the film is as LCD's Protective film and compensation film.These films can be prepared by solvent cast --- as described in US2009/0096962, or pass through It is prepared by melting extrusion --- as described in US8344134, at them not and in contradictory degree described herein, and this two patents text It offers and the present invention is fully incorporated to it.

When being used as protective film, the film is laminated to the either side of orientation, iodate PVOH polarizing coating usually to protect The PVOH layers, from scraping and moisture, while also adding the rigidity of structure.When being used as compensation film (or piece), they can be with Polarizing film stacked body is laminated together or can be included between polarizer and liquid crystal layer.These compensation films can improve LCD Contrast ratio, wide viewing angle and color displacement performance.The reason of this critical function, is, for typically intersecting used in LCD For polarizer group, diagonally there is the leakage of apparent light (leading to the contrast ratio of difference), in particular with the increasing at visual angle Add even more so.It is known that the various combination of optical film can be used for correcting or " compensation " this light leakage.These compensation Film must have certain well-defined delay (perhaps birefringence) values, and it is the type or mode used according to liquid crystal cell And change, because liquid crystal cell itself will also assign undesirable optical delay in the certain degree that must be corrected.

Compensation film quantifies generally according to birefringence, and birefringence transfers to be related to refractive index n.For cellulose esters, folding The rate of penetrating is about 1.46-1.50.For non-oriented isotropic material, refractive index will be it is identical, but regardless of the light of entrance The polarization state of wave.Material become orientation or when anisotropy, refractive index becomes dependent on material direction.For the present invention Purpose, there are three kinds of important refractive index, are expressed as n_x、n_yAnd n_z, correspond respectively to MD, TD and thickness direction.Become in material When obtaining more anisotropy (for example, passing through stretching), the difference between any two refractive index will increase.It is this in refractive index Difference is referred to as the birefringence of material --- for the specific combination of refractive index.Because there are many optional material directions Combination, therefore correspondingly there will be different birefringence values.Two kinds of most common birefringence parameters are defined as Δ_e=n_x- n_yPlanar birefringence rate and be defined as Δ_th=n_z-(n_x+n_yThickness birefringence (the Δ of)/2_th).Birefringence_eBe in MD and The measurement being orientated in opposite plane between TD, and be nondimensional.On the contrary, being orientated relative to mean level of the sea, Δ_thIt gives The measurement of thickness direction orientation.

Optical delay (R) is related to birefringence multiplied by the thickness (d) of film: R_e=Δ_eD=(n_x-n_y)d；R_th=Δ_thD= [n_z-(n_x+n_y)/2].Delay is the direct measurement that the relative phase between two orthogonal light waves moves, and is usually with nanometer (nm) unit describes.It should be noted that R_thDefinition change with some authors, especially relate to symbol (±).

Material is also known that birefringent/delay behavior about them and changes.For example, most of material is when stretched It will show along the higher refractive index of draw direction and perpendicular to the lower refractive index of stretching.This is because of in molecule In level, refractive index generally along the axis of polymer chain it is higher and perpendicular to the chain it is lower.These materials are commonly referred to as " just It is birefringent ", and most conventional polymer is represented, including all conventional at present cellulose esters.

In order to avoid obscuring, the birefringent behavior of polymer molecule itself will be called " intrinsic birefringent (rate) ", and be A kind of characteristic of polymer.For materials optical viewpoint, intrinsic birefringence is the measurement of such birefringence: it will go out (for most of polymer, this is when present material is completely stretched and all chain is ideally aligned in one direction One theoretical limit, because they are never perfectly aligned).For objects of the invention, it is also provided given polymer pair In the measurement of the sensibility of the chain orientation of specified rate.For example, the high sample of intrinsic birefringence will performance in film forming process The bigger birefringence of the sample lower than intrinsic birefringence out, even if the relative stress level in film is roughly the same.

Polymer can have positive and negative or zero intrinsic birefringence.Negative (intrinsic) birefringent polymer is shown vertical In refractive index (relative to parallel direction) higher on draw direction, therefore also has and bear intrinsic birefringence.Certain styrene Class and acrylic compounds are known with intrinsic birefringent behavior is born, this is attributed to their rather huge side groups.Depending on forming, one A little cellulose esters with aromatic ring structure also show to bear intrinsic birefringence.On the contrary, zero intrinsic birefringence is a kind of special Situation represents and does not show birefringence when stretching and therefore with the material of zero intrinsic birefringence.Such material It can be ideal for optical application, because they can be molded, be stretched or be pressurized in process power, Without showing any optical delay or distortion.

Practical compensation film for LCD can take various forms, including biaxial film (wherein all three refractive index not Together, and there is two optical axises) and uniaxial film (have only one optical axis, wherein two in three refractive index are identical ).There is also other kinds of compensation films, and wherein optical axis distorts or tilt through the thickness of film (such as plate-like film), still These are not too important for the present invention generally for understanding.Emphasis is the type for the compensation film that can be manufactured by the double of polymer The limitation of refracting characteristic (that is, positive and negative or zero intrinsic birefringence).

Depending on the operational mode of LCD display device, compensation film or piece can be taken various forms.For example, C piece compensation film It is isotropic in an x-y plane, and described can be positive (+C) or bear (- C).In the case where+C piece, n_x=n_y <n_z.In the case where-C piece, n_x=n_y>n_z.Another example is A piece compensation film, be in the direction y-z it is isotropic, equally, Described can be positive (+A) or bear (- A).In the case where+A piece, n_x>n_y=n_z.In the case where-A piece, n_x<n_y=n_z。

In general, aliphatic cellulose esters provides about 0 R for arriving about -350nm at 60 μm of film thickness_thValue.Influence is seen The R examined_thMost important factor be to replace base type and DS_OH.Use DS_OHThe film of low-down cellulose mixed esters production R_thValue is about 0 to about -50nm.United States Patent (USP) No.8344134.By the DS for dramatically increasing cellulose mixed esters_OHPerformance Bigger R can be obtained out_thAbsolute value, R_thIt is about -100 to about -350nm.U. S. application No.2009/0096962. Depending on DS_OH, R that cellulose acetate usually provides_thValue is about -40 to about -90nm.

In order to use cellulose esters of the invention to obtain desired R_eValue, it is necessary to stretched film.By adjusting tension bar Part --- such as draft temperature, tension-type (uniaxial or twin shaft), draw ratio, preheating time and temperature and stretching after annealing Desired R may be implemented in time and temperature_eAnd R_th.Accurate stretching condition depends on the concrete composition of cellulose esters, plasticizer Amount and type and concrete composition glass transition temperature.Therefore, specific stretching condition can be widely varied.It stretches Temperature can be 140 DEG C -190 DEG C.Draw ratio can be 1.0-1.3 on longitudinal direction (MD), and can be 1.1- on TD 1.8.Preheating time can be 10-300s, and preheating temperature can be identical as draft temperature.The after annealing time can be 0-300s, After annealing temperature can be 10 DEG C -40 DEG C lower than draft temperature.Film thickness depends on the film thickness before stretching and depends on drawing Stretch condition.After the stretch, preferred film thickness is about 10 μm-about 200 μm.When film thickness is about 20 μm-about 100 μm When, more preferably.When film thickness is about 25 μm-about 70 μm, even more preferably from.

The cellulose esters that regioselectivity replaces

The invention discloses the cellulose esters that a kind of regioselectivity replaces, which includes: (i) multiple R¹-CO- Substituent group；And (ii) multiple hydroxyl substituents.Wherein R¹The degree of substitution (" C2DS of-CO- on the position C2_R1") in about 0.2- In the range of about 1.0, wherein R¹The degree of substitution (" C3DS of-CO- on the position C3_R1") in the range of about 0.2- about 1.0 It is interior, wherein R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") in the range of about 0.5 about 0-, wherein hydroxyl replaces Degree is in the range of about 2.6 about 0-.Wherein, R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) alkenyl； (C_3-7) naphthenic base；(C_6-20) aryl, wherein aryl is unsubstituted or with 1-6 R²What group replaced；Or 5-20 member is miscellaneous Aryl, the heteroaryl contain the 1-3 hetero atom independently selected from oxygen, sulphur and nitrogen, wherein the heteroaryl be it is unsubstituted or With 1-6 R³What group replaced.Wherein, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkane Oxygroup, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.Wherein, R³Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.

In one embodiment, wherein the degree of substitution of hydroxyl in the range of about 2.6 about 0.5-.In one embodiment, Wherein the degree of substitution of hydroxyl is in the range of about 2.6 about 0.1-.In one embodiment, wherein the degree of substitution of hydroxyl about In the range of 0.2- about 2.6.In one embodiment, wherein the degree of substitution of hydroxyl in the range of about 2.6 about 0.3-.In In one embodiment, in the range of wherein the degree of substitution of hydroxyl is about 0.4- about 2.6.

In one embodiment of cellulose esters that regioselectivity replaces, the cellulose esters of regioselectivity substitution is divided equally again Son amount (" Mw ") is in the range of about 5000Da- about 250000Da.One in the cellulose esters that regioselectivity replaces is real It applies in example, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about 25000Da- about 250000Da's In range.In an embodiment of the cellulose esters that regioselectivity replaces, the weight for the cellulose esters that regioselectivity replaces is equal Molecular weight (" Mw ") is in the range of about 50000Da- about 250000Da.The one of the cellulose esters that regioselectivity replaces In embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is in about 80000Da- about 250000Da In the range of.In an embodiment of the cellulose esters that regioselectivity replaces, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" Mw ") is in the range of about 80000Da- about 150000Da.In the cellulose esters that regioselectivity replaces In one embodiment, regioselectivity replace cellulose esters weight average molecular weight (" Mw ") about 100000Da- about In the range of 150000Da.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl Or (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogen Generation (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro. In one kind of this embodiment, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 80000Da- In the range of about 250000Da.In one kind of this embodiment, the Weight-average molecular for the cellulose esters that regioselectivity replaces Measure (" M_w") in the range of about 80000Da- about 150000Da.In one kind of this embodiment, regioselectivity is taken The weight average molecular weight (" M of the cellulose esters in generation_w") in the range of about 100000Da- about 150000Da.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹Selected from (C_1-20) alkyl.In this embodiment In one kind, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about 250000Da's In range.In one kind of this embodiment, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about In the range of 80000Da- about 150000Da.In one kind of this embodiment, the cellulose esters of regioselectivity substitution Weight average molecular weight (" M_w") in the range of about 100000Da- about 150000Da.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹It is (C_6-20) aryl, wherein the aryl is not take In generation, either uses 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In one kind of this embodiment, regional choice Property replace cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In this reality It applies in one kind of example, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In one kind of this embodiment, the weight average molecular weight for the cellulose esters that regioselectivity replaces (“M_w") in the range of about 100000Da- about 150000Da.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹Selected from methyl, ethyl, propyl, 1- ethyl-penta Base-, phenyl, 3,4,5- trimethoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In one kind of this embodiment In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da It is interior.In one kind of this embodiment, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about In the range of 80000Da- about 150000Da.In one kind of this embodiment, the cellulose esters of regioselectivity substitution Weight average molecular weight (" M_w") in the range of about 100000Da- about 150000Da.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹Degree of substitution of-the CO- on the position C6 (“C6DS_R1") in the range of about 0.3 about 0-.In one kind of this embodiment, the cellulose of regioselectivity substitution The weight average molecular weight (" Mw ") of ester is in the range of about 80000Da- about 250000Da.In one kind of this embodiment, The weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is in the range of about 80000Da- about 150000Da. In one kind of this embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, In the aryl be unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) Alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, area The weight average molecular weight (" M for the cellulose esters that field selectivity replaces_w") in the range of about 80000Da- about 250000Da.In In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w”) In the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl.In a this kind of subclass, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da It is interior.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- In the range of about 150000Da.

In one kind of this embodiment, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R² What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, regioselectivity The weight average molecular weight (" M of substituted cellulose esters_w") in the range of about 80000Da- about 150000Da.This kind of one In subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- about 150000Da In the range of.

In one kind of this embodiment, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, the fiber of regioselectivity substitution The weight average molecular weight (" M of plain ester_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, area The weight average molecular weight (" M for the cellulose esters that field selectivity replaces_w") in the range of about 80000Da- about 150000Da.In In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 100000Da- about In the range of 150000Da.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹Degree of substitution of-the CO- on the position C6 (“C6DS_R1") in the range of about 0.1 about 0-.In one kind of this embodiment, the cellulose of regioselectivity substitution The weight average molecular weight (" Mw ") of ester is in the range of about 80000Da- about 250000Da.In one kind of this embodiment, The weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is in the range of about 80000Da- about 150000Da. In one kind of this embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, In the aryl be unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) Alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w”) In the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl.In a this kind of subclass, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da It is interior.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- In the range of about 150000Da.

In one kind of this embodiment, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R² What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, regioselectivity The weight average molecular weight (" M of substituted cellulose esters_w") in the range of about 80000Da- about 150000Da.This kind of one In subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- about 150000Da In the range of.

In one kind of this embodiment, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, the fiber of regioselectivity substitution The weight average molecular weight (" M of plain ester_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, area The weight average molecular weight (" M for the cellulose esters that field selectivity replaces_w") in the range of about 80000Da- about 150000Da.In In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 100000Da- about In the range of 150000Da.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹Degree of substitution of-the CO- on the position C6 (“C6DS_R1") in the range of about 0.08 about 0-.In one kind of this embodiment, the cellulose of regioselectivity substitution The weight average molecular weight (" Mw ") of ester is in the range of about 80000Da- about 250000Da.In one kind of this embodiment, The weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is in the range of about 80000Da- about 150000Da. In one kind of this embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, In the aryl be unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) Alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w”) In the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl.In a this kind of subclass, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da It is interior.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- In the range of about 150000Da.

In one kind of this embodiment, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R² What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, regioselectivity The weight average molecular weight (" M of substituted cellulose esters_w") in the range of about 80000Da- about 150000Da.This kind of one In subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- about 150000Da In the range of.

In one kind of this embodiment, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, the fibre of regioselectivity substitution Tie up the weight average molecular weight (" M of plain ester_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") big in about 100000Da- In the range of about 150000Da.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹Degree of substitution of-the CO- on the position C6 (“C6DS_R1") in the range of about 0.06 about 0-.In one kind of this embodiment, the cellulose of regioselectivity substitution The weight average molecular weight (" Mw ") of ester is in the range of about 80000Da- about 250000Da.In one kind of this embodiment, The weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is in the range of about 80000Da- about 150000Da. In one kind of this embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, In the aryl be unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) Alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w”) In the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl.In a this kind of subclass, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da It is interior.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- In the range of about 150000Da.

In one kind of this embodiment, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R² What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, regioselectivity The weight average molecular weight (" M of substituted cellulose esters_w") in the range of about 80000Da- about 150000Da.This kind of one In subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- about 150000Da In the range of.

In one kind of this embodiment, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, the fibre of regioselectivity substitution Tie up the weight average molecular weight (" M of plain ester_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") big in about 100000Da- In the range of about 150000Da.

In an embodiment of composition (compositions of matter), R¹Degree of substitution of-the CO- on the position C6 (“C6DS_R1") in the range of about 0.04 about 0-.In one kind of this embodiment, the cellulose of regioselectivity substitution In the range of the weight average molecular weight (" Mw ") of ester is about 80000Da- about 250000Da.In one kind of this embodiment, The weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is in the range of about 80000Da- about 150000Da. In one kind of this embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, In the aryl be unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) Alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w”) In the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl.In a this kind of subclass, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da It is interior.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- In the range of about 150000Da.

In one kind of this embodiment, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R² What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, regioselectivity The weight average molecular weight (" M of substituted cellulose esters_w") in the range of about 80000Da- about 150000Da.This kind of one In subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- about 150000Da In the range of.

In one kind of this embodiment, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, the fiber of regioselectivity substitution The weight average molecular weight (" M of plain ester_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, area The weight average molecular weight (" M for the cellulose esters that field selectivity replaces_w") in the range of about 80000Da- about 150000Da.In In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 100000Da- about In the range of 150000Da.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹It is (C_1-20) alkyl.Replace in regioselectivity Cellulose esters an embodiment in, R¹It is halogenated (C_1-20) alkyl.In an embodiment of the cellulose esters that regioselectivity replaces In, R¹It is (C_2-20) alkenyl.In an embodiment of the cellulose esters that regioselectivity replaces, R¹It is (C_3-7) naphthenic base.In area In one embodiment of the cellulose esters that field selectivity replaces, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or uses 1- 6 R²What group replaced, wherein R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, Halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In an embodiment of the cellulose esters that regioselectivity replaces, R¹ It is 5-20 unit's heteroaryl, contains the 1-3 hetero atom independently selected from oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted Or with 1-6 R³What group replaced, R³Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkane Oxygroup, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkane Base；(C_2-20) alkenyl；(C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R²What group replaced；Alternatively, 5-20 Unit's heteroaryl contains the 1-3 hetero atom independently selected from oxygen, sulphur and nitrogen, and wherein the heteroaryl is unsubstituted or uses 1-6 R³What group replaced.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl Or (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogen Generation (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.

In an embodiment of the cellulose esters that regioselectivity replaces, R¹Selected from methyl, ethyl, propyl, 1- ethyl-penta Base-, phenyl, 3,4,5- trimethoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.

In an embodiment of the cellulose esters that regioselectivity replaces, the cellulose esters that regioselectivity replaces also includes Multiple R⁴- CO- substituent group, wherein R⁴The degree of substitution (" C6DS of-CO- on the position C6_R4") in the range of about 0.1- about 1.0 It is interior.Wherein R⁴It is selected from: (C_1-20) alkyl；Halogenated (C_1-5) alkyl；(C_2-20) alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, wherein The aryl is unsubstituted or with 1-6 R⁵What group replaced；Alternatively, monocycle or bicyclic heteroaryl, contain independently The 1-3 hetero atom selected from oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R⁶What group replaced.R⁵Choosing From (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) Aryl or nitro.R⁶Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.

In one kind of this embodiment, R⁴The degree of substitution (" C2DS of-CO- on the position C2_R4") in about 0- about 0.5 In the range of, wherein R⁴The degree of substitution (" C3DS of-CO- on the position C3_R4") in the range of about 0.5 about 0-.This kind of A subclass in, weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, weight average molecular weight (" M_w") in the range of about 80000Da- about 100000Da.In a this kind of subclass, divide equally again Son amount (" M_w") in the range of about 100000Da- about 250000Da.

In one kind of this embodiment, R⁴The degree of substitution (" C2DS of-CO- on the position C2_R4") in about 0- about 0.4 In the range of, wherein R⁴The degree of substitution (" C3DS of-CO- on the position C3_R4") in the range of about 0.4 about 0-.This kind of A subclass in, weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, weight average molecular weight (" M_w") in the range of about 80000Da- about 100000Da.In a this kind of subclass, divide equally again Son amount (" M_w") in the range of about 100000Da- about 250000Da.

In one kind of this embodiment, R⁴The degree of substitution (" C2DS of-CO- on the position C2_R4") in about 0- about 0.3 In the range of, wherein R⁴The degree of substitution (" C3DS of-CO- on the position C3_R4") in the range of about 0.3 about 0-.This kind of A subclass in, weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, weight average molecular weight (" M_w") in the range of about 80000Da- about 100000Da.In a this kind of subclass, divide equally again Son amount (" M_w") in the range of about 100000Da- about 250000Da.

In one kind of this embodiment, R⁴The degree of substitution (" C2DS of-CO- on the position C2_R4") in about 0- about 0.2 In the range of, wherein R⁴The degree of substitution (" C3DS of-CO- on the position C3_R4") in the range of about 0.2 about 0-.This kind of A subclass in, weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, weight average molecular weight (" M_w") in the range of about 80000Da- about 100000Da.In a this kind of subclass, divide equally again Son amount (" M_w") in the range of about 100000Da- about 250000Da.

In one kind of this embodiment, weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da It is interior.

In one kind of this embodiment, weight average molecular weight (" M_w") in the range of about 80000Da- about 100000Da It is interior.

In one kind of this embodiment, weight average molecular weight (" M_w") in the model of about 100000Da- about 250000Da In enclosing.

In one kind of this embodiment, R⁴It is (C_1-20) alkyl.In one kind of this embodiment, R⁴It is halogenated (C_1-5) Alkyl.

In one kind of this embodiment, R⁴It is (C_2-20) alkenyl.

In one kind of this embodiment, R⁴It is (C_3-7) naphthenic base.

One kind in such an embodiment, R⁴It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R⁵ What group replaced, wherein R⁵Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen Element, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.

In one kind of this embodiment, R⁴Monocycle or bicyclic heteroaryl, contain independently selected from oxygen, sulphur and 1-3 hetero atom of nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R⁶What group replaced, R⁶Selected from (C_1-6) alkyl, Halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitre Base.

In one kind of this embodiment, R⁴Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, R⁴It is methyl.This kind of one In subclass, R⁴It is ethyl.In a this kind of subclass, R⁴It is propyl.In a this kind of subclass, R⁴It is 1- ethyl-pentyl-.In In a this kind of subclass, R⁴It is phenyl.In a this kind of subclass, R⁴It is 3,4,5- trimethoxyphenyl.In a this kind of subclass In, R⁴It is 2- naphthalene.In a this kind of subclass, R⁴It is benzothienyl.In a this kind of subclass, R⁴It is heptadecyl.

In one embodiment, C6DS_R1-CO-Less than 0.1.In one embodiment, C6DS_R1-CO-Less than 0.08.In an embodiment In, C6DS_R1-CO-Less than 0.06.In one embodiment, C6DS_R1-CO-Less than 0.05.In one embodiment, C6DS_R1-CO-It is less than 0.04.In one embodiment, C6DS_R1-CO-Less than 0.02.

In one embodiment, R¹- CO- is selected from acetyl group, propiono, bytyry, benzoyl, naphthoyl, 3,4,5- Trimethoxybenzoy, xenyl-CO-, benzoyl-benzoyl or benzothienyl-CO-.

In one embodiment, R¹- CO- is propiono.In one kind of this embodiment, the degree of substitution of propiono is (that is, R¹- CO- is propiono) it is about 1.0- about 1.4, degree of substitution (" C2DS of the propiono in the position C2_Pr") it is 0.6-0.9, propiono Degree of substitution (" C3DS in the position C3_Pr") it is about 0.3- about 0.5.In a this kind of subclass, propiono is in the position C6 Degree of substitution (" C6DS_Pr") less than 0.05.

In one embodiment, R¹- CO- is the combination comprising benzoyl and naphthoyl.In one kind of this embodiment In, the degree of substitution of benzoyl is about 0.2- about 1.2, and the degree of substitution of naphthoyl is about 0.8- about 1.8.

In one kind of this embodiment, the degree of substitution of benzoyl is about 0.4- about 0.8, naphthoyl degree of substitution It is about 1.2- about 1.6, the degree of substitution of the benzoyl and naphthoyl that add up on the position C6 is less than 0.05.

In one embodiment, R¹- CO- is comprising propiono and (C_6-20) aryl combination.In one kind of this embodiment In, in the propiono and (C that the position C6 adds up to_6-20) aryl degree of substitution less than 0.1.

In one embodiment, R¹- CO- is the combination comprising propiono and benzoyl.In one kind of this embodiment, third The degree of substitution of acyl group is about 0.4- about 0.7, and the degree of substitution of benzoyl is about 0.2- about 0.5, total in the position C6 Propiono and benzoyl degree of substitution less than 0.05.

In one kind of this embodiment, propiono degree of substitution is about 1.1- about 1.8, and the degree of substitution of benzoyl is About 0.1- about 0.5, in the position C6, the degree of substitution of total propiono and benzoyl is less than 0.05.

In one embodiment, R¹- CO- is the combination comprising propiono and naphthoyl.In one kind of this embodiment, The degree of substitution of propiono is in the range of 0.2-0.9, the degree of substitution of naphthoyl in the range of 0.4-1.4

In one embodiment, R¹- CO- is the combination comprising propiono or 5-20 unit's heteroaryl, and the heteroaryl contains The 1-3 hetero atom independently selected from oxygen, sulphur and nitrogen.In one kind of this embodiment, the degree of substitution of propiono is in 0.2-0.4 In the range of, the degree of substitution of naphthoyl is in the range of 0.9-1.1.

In one embodiment, R¹- CO- is comprising propiono and (C_6-20) alkyl-CO- combination.

In one embodiment, R¹- CO- is comprising acetyl group and (C_6-20) aryl-CO- combination.The one of this embodiment In class, the degree of substitution of acetyl group is about 0.7- about 0.9, (C_6-20) degree of substitution of aryl-CO- is about 0.1- about 0.5, In the acetyl group and (C that the position C6 adds up to_6-20) aryl-CO- degree of substitution less than 0.1.

In one embodiment, R¹- CO- is the combination comprising acetyl group and 5-20 unit's heteroaryl, and the heteroaryl contains solely The on the spot 1-3 hetero atom selected from oxygen, sulphur and nitrogen.In one kind of this embodiment, the degree of substitution of acetyl group is about 0.8- The degree of substitution of about 1.1,5-20 unit's heteroaryl is about 0.1- about 0.3, the heteroaryl contain independently selected from oxygen, sulphur and 1-3 hetero atom of nitrogen, wherein in the degree of substitution of the total acetyl group in the position C6 and benzoyl less than 0.1.

Disclosed herein as well is the cellulose esters that a kind of regioselectivity replaces, and it includes (i) multiple R¹- CO- replaces Base；(ii) multiple R⁴- CO- substituent group；(iii) multiple hydroxyl substituents.Wherein R¹Degree of substitution of-the CO- on the position C2 (“C2DS_R1") in the range of about 1.0 about 0.2-, wherein R¹The degree of substitution (" C3DS of-CO- on the position C3_R1") big In the range of about 0.2- about 1.0, wherein R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") about 0-'s about 0.5 In range, wherein R⁴The degree of substitution (" C6DS of-CO- on the position C6_R4") in the range of about 1.0 about 0.1-, wherein hydroxyl The degree of substitution of base is in the range of about 2.6 about 0-.Wherein R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) Alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R²What group replaced；Alternatively, 5-20 unit's heteroaryl contains the 1-3 hetero atom independently selected from oxygen, sulphur and nitrogen, wherein the heteroaryl be it is unsubstituted or Person is with 1-6 R³What group replaced.Wherein R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) Alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.Wherein R³Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.Wherein R⁴It is selected from: (C_1-20) alkyl；Halogenated (C_1-5) alkyl；(C_2-20) alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, wherein the aryl is unsubstituted Or with 1-6 R⁵What group replaced；Alternatively, monocycle or bicyclic heteroaryl, contain independently selected from oxygen, sulphur and nitrogen 1-3 hetero atom, wherein the heteroaryl is unsubstituted or with 1-6 R⁶What group replaced.R⁵Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.R⁶Choosing From (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) Aryl or nitro.

In one embodiment, wherein the degree of substitution of hydroxyl in the range of about 2.6 about 0.5-.In one embodiment, Wherein the degree of substitution of hydroxyl is in the range of about 2.6 about 0.1-.In one embodiment, wherein the degree of substitution of hydroxyl about In the range of 0.2- about 2.6.In one embodiment, wherein the degree of substitution of hydroxyl in the range of about 2.6 about 0.3-.In In one embodiment, wherein the degree of substitution of hydroxyl is in the range of about 2.6 about 0.4-.

In one embodiment, R¹- CO- is selected from: acetyl group, propiono, bytyry, benzoyl, naphthoyl, 3,4,5- Trimethoxybenzoy, xenyl-CO-, benzoyl-benzoyl-or benzothiophene-CO-；Wherein R⁴- CO- is selected from: Acetyl group, propiono, bytyry, benzoyl, acetyl group, naphthoyl, 3,4,5- trimethoxybenzoy, xenyl- CO-, benzoyl-benzoyl-or benzothiophene-CO-.

In one embodiment, C6DS_R1-CO-Less than 0.1.In one embodiment, C6DS_R1-CO-Less than 0.08.In an embodiment In, C6DS_R1-CO-Less than 0.06.In one embodiment, C6DS_R1-CO-Less than 0.05.In one embodiment, C6DS_R1-CO-It is less than 0.04.In one embodiment, C6DS_R1-CO-Less than 0.02.

In one embodiment, R¹- CO- is propiono.

In one kind of this embodiment, R⁴- CO- is (C_6-20) aryl-CO-.

In one kind of this embodiment, R⁴- CO- is valeryl and (C_6-20) aryl-CO- combination.This kind of one In subclass, (C_6-20) aryl-CO- be selected from benzoyl and naphthoyl.In a subclass of this subclass, valeryl Degree of substitution is 0.6-0.9；(C_6-20) degree of substitution of aryl-CO- is 0.2-0.5.

In one kind of this embodiment, the degree of substitution of propiono is about 1.0- about 1.4, the propiono in the position C2 Degree of substitution is 0.6-0.9, is about 0.3- about 0.5 in the degree of substitution of C3 propiono.

In a this kind of subclass, in the position C6, the degree of substitution of propiono is less than 0.05.In a subclass of this subclass In, the degree of substitution of valeryl is 0.6-0.9；(C_6-20) degree of substitution of aryl-CO- is 0.2-0.5.

In a this kind of subclass, R⁴- CO- is (C_6-20) aryl-CO-.

In a this kind of subclass, R⁴- CO- is valeryl and (C_6-20) aryl-CO- combination.The one of this subclass In subclass, (C_6-20) aryl-CO- be selected from benzoyl and naphthoyl.In a sub- subclass of this seed subclass, it is used for The degree of substitution of valeryl is 0.6-0.9；(C_6-20) degree of substitution of aryl-CO- is 0.2-0.5.The one of this seed subclass In sub- subclass, in the position C6, the degree of substitution of propiono is less than 0.05.In the sub- subclass of a son of this seed subclass, newly The degree of substitution of valeryl is 0.6-0.9；(C_6-20) degree of substitution of aryl-CO- is 0.2-0.5.

In one embodiment, R¹- CO- is the combination comprising benzoyl and naphthoyl.

In one kind of this embodiment, R⁴- CO- is (C_1-6) alkyl-CO-.

In a this kind of subclass, benzoyl degree of substitution is about 0.2- about 1.2, wherein the degree of substitution of naphthoyl It is about 0.8- about 1.8, wherein (C_1-6) alkyl-CO- degree of substitution less than 0.5.

In a subclass of this subclass, R⁴- CO- is propiono.

In one embodiment, wherein R¹- CO- is the combination of propiono and benzoyl.

In one kind of this embodiment, R⁴- CO- is the combination of propiono and benzoyl.

In a this kind of subclass, total degree of substitution of the benzoyl in total position C2 and C3 is 0.1-0.6, third Degree of substitution of the acyl group in total position C2 and C3 is 0.5-1.4, and degree of substitution of the benzoyl in the position C6 is 0-0.8, propionyl The degree of substitution of base is 0-1.0.

In a subclass of this subclass, benzoyl is 0.1-0.2 in the degree of substitution of C6, and wherein propiono is C6's C6 degree of substitution is 0.4-0.8.

In a this kind of subclass, total degree of substitution of the benzoyl in total position C2 and C3 is 0.05-2.0, Degree of substitution of the propiono in total position C2 and C3 is 0.5-1.4, and degree of substitution of the benzoyl in the position C6 is 0-0.8, third The degree of substitution of acyl group is 0-1.0.

In a subclass of this subclass, benzoyl is 0.1-0.2 in the degree of substitution of C6, and wherein propiono is C6's C6 degree of substitution is 0.4-0.8.

In a this kind of subclass, total degree of substitution of the benzoyl in total position C2 and C3 is 0.6-2.0, third Degree of substitution of the acyl group in total position C2 and C3 is 0.5-1.4, and degree of substitution of the benzoyl in the position C6 is 0-0.8, propionyl The degree of substitution of base is 0-1.0.

In a subclass of this subclass, benzoyl is 0.1-0.2 in the degree of substitution of C6, and wherein propiono is C6's C6 degree of substitution is 0.4-0.8.

Disclosed herein as well is a kind of regioselectivity replace trifluoroacetyl group cellulose esters, it includes:

(i) multiple trifluoroacetyl group (trifluoroacetyl) substituent groups,

Wherein the degree of substitution (" C2DS on the position C2_TFA") it is about 0- about 0.1,

Wherein the degree of substitution (" C3DS on the position C3_TFA") it is about 0- about 0.1,

Wherein the degree of substitution (" C6DS on the position C6_TFA") it is about 0.9- about 1.0,

The weight average molecular weight (" M for the trifluoroacetyl group cellulose esters that wherein regioselectivity replaces_w") about In the range of 50000Da- about 600000Da.

In one kind of the embodiment, C2DS_TFAIt is about 0- about 0.05, C3DS_TFAIt is about 0- about 0.05.At this In one kind of embodiment, C2DS_TFAIt is about 0- about 0.02, C3DS_TFAIt is about 0- about 0.02.In one kind of the embodiment In, C2DS_TFAIt is about 0- about 0.01, C3DS_TFAIt is about 0- about 0.02.

In one kind of this embodiment, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about In the range of 50000Da- about 250000Da.In one kind of this embodiment, the cellulose esters of regioselectivity substitution Weight average molecular weight (" M_w") in the range of about 50000Da- about 150000Da.

Film

This application discloses a kind of film, which includes cellulose esters, which includes: (i) multiple R¹- CO- replaces Base；(ii) multiple R⁴- CO- substituent group；(iii) multiple hydroxyl substituents.Wherein R¹Degree of substitution of-the CO- on the position C2 (“C2DS_R1") in the range of about 1.0 about 0.2-, wherein R¹The degree of substitution (" C3DS of-CO- on the position C3_R1") big In the range of about 0.2- about 1.0, wherein R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") about 0-'s about 0.5 In range, wherein R⁴The degree of substitution (" C6DS of-CO- on the position C6_R4") in the range of about 1.0 about 0.1-, wherein hydroxyl Base degree of substitution is in the range of about 2.6 about 0-.Wherein R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) alkene Base；(C_3-7) naphthenic base；(C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R²What group replaced；Alternatively, 5- 20 unit's heteroaryls contain the 1-3 hetero atom independently selected from oxygen, sulphur and nitrogen, wherein the heteroaryl be it is unsubstituted or With 1-6 R³What group replaced.Wherein R²It is selected from: (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkane Oxygroup, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.Wherein R³It is selected from: (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.Wherein R⁴It is selected from: (C_1-20) alkyl；Halogenated (C_1-5) alkyl；(C_2-20) alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, wherein the aryl is unsubstituted Or with 1-6 R⁵What group replaced；Alternatively, monocycle or bicyclic heteroaryl, contain independently selected from oxygen, sulphur and nitrogen 1-3 hetero atom, wherein the heteroaryl is unsubstituted or with 1-6 R⁶What group replaced.R⁵It is selected from: (C_1-6) alkyl, Halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitre Base.R⁶Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) cycloalkanes Base, (C_6-10) aryl or nitro.

In one embodiment, wherein the degree of substitution of hydroxyl in the range of about 2.6 about 0.5-.In one embodiment, Wherein the degree of substitution of hydroxyl is in the range of about 2.6 about 0.1-.In one embodiment, wherein the degree of substitution of hydroxyl about In the range of 0.2- about 2.6.In one embodiment, wherein the degree of substitution of hydroxyl in the range of about 2.6 about 0.3-.In In one embodiment, wherein the degree of substitution of hydroxyl is in the range of about 2.6 about 0.4-.

In an embodiment of regioselectivity cellulose esters, the weight average molecular weight for the cellulose esters that regioselectivity replaces (" Mw ") is in the range of about 5000Da- about 250000Da.In an embodiment of regioselectivity cellulose esters, region The weight average molecular weight (" Mw ") of the cellulose esters selectively replaced is in the range of about 25000Da- about 250000Da.In area In one embodiment of field selectivity cellulose esters, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 50000Da- about 250000Da.In an embodiment of regioselectivity cellulose esters, regioselectivity replaces Cellulose esters weight average molecular weight (" Mw ") in the range of about 80000Da- about 250000Da.In regioselectivity fibre In the embodiment for tieing up plain ester, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is big in about 80000Da- In the range of about 150000Da.In an embodiment of regioselectivity cellulose esters, the cellulose esters of regioselectivity substitution Weight average molecular weight (" Mw ") in the range of about 100000Da- about 150000Da.

In an embodiment of regioselectivity cellulose esters, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R²What group replaced, R²It is selected from: (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In In one kind of this embodiment, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") big in about 80000Da- In the range of about 250000Da.In one kind of this embodiment, the weight average molecular weight for the cellulose esters that regioselectivity replaces (“M_w") in the range of about 80000Da- about 150000Da.In one kind of this embodiment, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 100000Da- about 150000Da.

In an embodiment of regioselectivity cellulose esters, R¹Selected from (C_1-20) alkyl.In one kind of this embodiment In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da It is interior.In one kind of this embodiment, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about In the range of 80000Da- about 150000Da.In one kind of this embodiment, the cellulose esters of regioselectivity substitution Weight average molecular weight (" M_w") in the range of about 100000Da- about 150000Da.

In an embodiment of regioselectivity cellulose esters, R¹It is (C_6-20) aryl, wherein the aryl be it is unsubstituted or Person is with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alcoxyl Base, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In one kind of this embodiment, what regioselectivity replaced The weight average molecular weight (" M of cellulose esters_w") in the range of about 80000Da- about 250000Da.The one of this embodiment In class, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the model of about 80000Da- about 150000Da In enclosing.In one kind of this embodiment, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about In the range of 100000Da- about 150000Da.

In an embodiment of regioselectivity cellulose esters, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, benzene Base, 3,4,5- trimethoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In one kind of this embodiment, region The weight average molecular weight (" M of the cellulose esters selectively replaced_w") in the range of about 80000Da- about 250000Da.At this In one kind of kind embodiment, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In one kind of this embodiment, the weight average molecular weight for the cellulose esters that regioselectivity replaces (“M_w") in the range of about 100000Da- about 150000Da.

In an embodiment of film, R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") in the model of about 0- about 0.3 In enclosing.In one kind of this embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 80000Da- about 250000Da.In one kind of this embodiment, the cellulose esters of regioselectivity substitution Weight average molecular weight (" Mw ") is in the range of about 80000Da- about 150000Da.In one kind of this embodiment, region The weight average molecular weight (" Mw ") of the cellulose esters selectively replaced is in the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, In the aryl be unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) Alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w”) In the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl.In a this kind of subclass, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da It is interior.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- In the range of about 150000Da.

In one kind of this embodiment, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R² What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, regioselectivity The weight average molecular weight (" M of substituted cellulose esters_w") in the range of about 80000Da- about 150000Da.This kind of one In subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- about 150000Da In the range of.

In one kind of this embodiment, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, the fibre of regioselectivity substitution Tie up the weight average molecular weight (" M of plain ester_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") big in about 100000Da- In the range of about 150000Da.

In an embodiment of film, R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") in the model of about 0- about 0.1 In enclosing.In one kind of this embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 80000Da- about 250000Da.In one kind of this embodiment, the cellulose esters of regioselectivity substitution Weight average molecular weight (" Mw ") is in the range of about 80000Da- about 150000Da.In one kind of this embodiment, region The weight average molecular weight (" Mw ") of the cellulose esters selectively replaced is in the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, In the aryl be unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) Alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w”) In the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl.In a this kind of subclass, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da It is interior.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- In the range of about 150000Da.

In one kind of this embodiment, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R² What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, regioselectivity The weight average molecular weight (" M of substituted cellulose esters_w") in the range of about 80000Da- about 150000Da.This kind of one In subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- about 150000Da In the range of.

In one kind of this embodiment, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, the fiber of regioselectivity substitution The weight average molecular weight (" M of plain ester_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, area The weight average molecular weight (" M for the cellulose esters that field selectivity replaces_w") in the range of about 80000Da- about 150000Da.In In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 100000Da- about In the range of 150000Da.

In an embodiment of film, R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") about 0-'s about 0.08 In range.In one kind of this embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 80000Da- about 250000Da.In one kind of this embodiment, the cellulose esters of regioselectivity substitution Weight average molecular weight (" Mw ") is in the range of about 80000Da- about 150000Da.In one kind of this embodiment, region The weight average molecular weight (" Mw ") of the cellulose esters selectively replaced is in the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, In the aryl be unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) Alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w”) In the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl.In a this kind of subclass, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da It is interior.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- In the range of about 150000Da.

In one kind of this embodiment, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R² What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, regioselectivity The weight average molecular weight (" M of substituted cellulose esters_w") in the range of about 80000Da- about 150000Da.This kind of one In subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- about 150000Da In the range of.

In one kind of this embodiment, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, the fiber of regioselectivity substitution The weight average molecular weight (" M of plain ester_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, area The weight average molecular weight (" M for the cellulose esters that field selectivity replaces_w") in the range of about 80000Da- about 150000Da.In In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 100000Da- about In the range of 150000Da.

In an embodiment of film, R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") about 0-'s about 0.06 In range.In one kind of this embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 80000Da- about 250000Da.In one kind of this embodiment, the cellulose esters of regioselectivity substitution Weight average molecular weight (" Mw ") is in the range of about 80000Da- about 150000Da.In one kind of this embodiment, region The weight average molecular weight (" Mw ") of the cellulose esters selectively replaced is in the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, In the aryl be unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) Alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w”) In the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl.In a this kind of subclass, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da It is interior.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- In the range of about 150000Da.

In one kind of this embodiment, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R² What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, regioselectivity The weight average molecular weight (" M of substituted cellulose esters_w") in the range of about 80000Da- about 150000Da.This kind of one In subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- about 150000Da In the range of.

In one kind of this embodiment, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, the fiber of regioselectivity substitution The weight average molecular weight (" M of plain ester_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, area The weight average molecular weight (" M for the cellulose esters that field selectivity replaces_w") in the range of about 80000Da- about 150000Da.In In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 100000Da- about In the range of 150000Da.

In an embodiment of film, R¹The degree of substitution (" C6DS of-CO- on the position C6_R1") about 0-'s about 0.04 In range.In one kind of this embodiment, the weight average molecular weight (" Mw ") for the cellulose esters that regioselectivity replaces is about In the range of 80000Da- about 250000Da.In one kind of this embodiment, the cellulose esters of regioselectivity substitution Weight average molecular weight (" Mw ") is in the range of about 80000Da- about 150000Da.In one kind of this embodiment, region The weight average molecular weight (" Mw ") of the cellulose esters selectively replaced is in the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, In the aryl be unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) Alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 250000Da. In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 80000Da- about In the range of 150000Da.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w”) In the range of about 100000Da- about 150000Da.

In one kind of this embodiment, R¹Selected from (C_1-20) alkyl.In a this kind of subclass, regioselectivity replaces Cellulose esters weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 80000Da- about 150000Da It is interior.In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- In the range of about 150000Da.

In one kind of this embodiment, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R² What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.In a this kind of subclass, the weight for the cellulose esters that regioselectivity replaces Average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, regioselectivity The weight average molecular weight (" M of substituted cellulose esters_w") in the range of about 80000Da- about 150000Da.This kind of one In subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in about 100000Da- about 150000Da In the range of.

In one kind of this embodiment, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- tri- Methoxyphenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, the fiber of regioselectivity substitution The weight average molecular weight (" M of plain ester_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass, area The weight average molecular weight (" M for the cellulose esters that field selectivity replaces_w") in the range of about 80000Da- about 150000Da.In In a this kind of subclass, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about 100000Da- about In the range of 150000Da.

In an embodiment of film, R¹It is (C_1-20) alkyl.In an embodiment of composition, R¹It is halogenated (C_1-20) alkane Base.In an embodiment of composition, R¹It is (C_2-20) alkenyl.In an embodiment of composition, R¹It is (C_3-7) naphthenic base.In In one embodiment of composition, R¹It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R²What group replaced, Wherein R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) cycloalkanes Base, (C_6-10) aryl or nitro.In an embodiment of composition, R¹5-20 unit's heteroaryl, contain independently selected from 1-3 hetero atom of oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R³What group replaced, R³It is selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) virtue Base or nitro.

In an embodiment of film, R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) alkenyl；(C_6-20) virtue Base, wherein the aryl is unsubstituted or with 1-6 R²What group replaced；Alternatively, 5-20 unit's heteroaryl, contains independently The 1-3 hetero atom selected from oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R³What group replaced.

In an embodiment of film, R¹Selected from (C_1-20) alkyl, halogenated (C_1-20) alkyl or (C_6-20) aryl, wherein should Aryl is unsubstituted or with 1-6 R²What group replaced, R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alcoxyl Base, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.

In an embodiment of film, R¹Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- trimethoxy Base phenyl, 2- naphthalene, benzothienyl or heptadecyl.

In an embodiment of film, the cellulose esters that regioselectivity replaces also includes multiple R⁴- CO- substituent group, wherein R⁴The degree of substitution (" C6DS of-CO- on the position C6_R4") in the range of about 1.0 about 0.1-.Wherein R⁴It is selected from: (C_1-20) alkane Base；Halogenated (C_1-5) alkyl；(C_2-20) alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, wherein the aryl is unsubstituted or uses 1-6 R⁵What group replaced；Alternatively, monocycle or bicyclic heteroaryl, contain the 1-3 independently selected from oxygen, sulphur and nitrogen Hetero atom, wherein the heteroaryl is unsubstituted or with 1-6 R⁶What group replaced.R⁵Selected from (C_1-6) alkyl, halogenated (C_1-6) Alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.R⁶It is selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) virtue Base or nitro.

In one kind of this embodiment, R⁴The degree of substitution (" C2DS of-CO- on the position C2_R4") in about 0- about 0.5 In the range of, wherein R⁴The degree of substitution (" C3DS of-CO- on the position C3_R4") in the range of about 0.5 about 0-.This kind of A subclass in, weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, weight average molecular weight (" M_w") in the range of about 80000Da- about 100000Da.In a this kind of subclass, divide equally again Son amount (" M_w") in the range of about 100000Da- about 250000Da.

In one kind of this embodiment, R⁴The degree of substitution (" C2DS of-CO- on the position C2_R4") in about 0- about 0.4 In the range of, wherein R⁴The degree of substitution (" C3DS of-CO- on the position C3_R4") in the range of about 0.4 about 0-.This kind of A subclass in, weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, weight average molecular weight (" M_w") in the range of about 80000Da- about 100000Da.In a this kind of subclass, divide equally again Son amount (" M_w") in the range of about 100000Da- about 250000Da.

In one kind of this embodiment, R⁴The degree of substitution (" C2DS of-CO- on the position C2_R4") in about 0- about 0.3 In the range of, wherein R⁴The degree of substitution (" C3DS of-CO- on the position C3_R4") in the range of about 0.3 about 0-.This kind of A subclass in, weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, weight average molecular weight (" M_w") in the range of about 80000Da- about 100000Da.In a this kind of subclass, divide equally again Son amount (" M_w") in the range of about 100000Da- about 250000Da.

In one kind of this embodiment, R⁴The degree of substitution (" C2DS of-CO- on the position C2_R4") in about 0- about 0.2 In the range of, wherein R⁴The degree of substitution (" C3DS of-CO- on the position C3_R4") in the range of about 0.2 about 0-.This kind of A subclass in, weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da.In a this kind of subclass In, weight average molecular weight (" M_w") in the range of about 80000Da- about 100000Da.In a this kind of subclass, divide equally again Son amount (" M_w") in the range of about 100000Da- about 250000Da.

In one kind of this embodiment, weight average molecular weight (" M_w") in the range of about 80000Da- about 250000Da It is interior.

In one kind of this embodiment, weight average molecular weight (" M_w") in the range of about 80000Da- about 100000Da It is interior.

In one kind of this embodiment, weight average molecular weight (" M_w") in the model of about 100000Da- about 250000Da In enclosing.

In one kind of this embodiment, R⁴It is (C_1-20) alkyl.In one kind of this embodiment, R⁴It is halogenated (C_1-5) Alkyl.

In one kind of this embodiment, R⁴It is (C_2-20) alkenyl.

In one kind of this embodiment, R⁴It is (C_3-7) naphthenic base.

In one kind of this embodiment, R⁴It is (C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R⁵ What group replaced, wherein R⁵Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen Element, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.

In one kind of this embodiment, R⁴Monocycle or bicyclic heteroaryl, contain independently selected from oxygen, sulphur and 1-3 hetero atom of nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R⁶What group replaced, R⁶Selected from (C_1-6) alkyl, Halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitre Base.

In one kind of this implementation, R⁴Selected from methyl, ethyl, propyl, 1- ethyl-pentyl-, phenyl, 3,4,5- front three Phenyl, 2- naphthalene, benzothienyl or heptadecyl.In a this kind of subclass, R⁴It is methyl.In a this kind of son In class, R⁴It is ethyl.In a this kind of subclass, R⁴It is propyl.In a this kind of subclass, R⁴It is 1- ethyl-pentyl-.At this In one subclass of class, R⁴It is phenyl.In a this kind of subclass, R⁴It is 3,4,5- trimethoxyphenyl.In a this kind of subclass In, R⁴It is 2- naphthalene.In a this kind of subclass, R⁴It is benzothienyl.In a this kind of subclass, R⁴It is heptadecyl.

In an embodiment of film, film is uniaxial or twin shaft optical film.In one kind of this embodiment, film is single Axis optical film.In one kind of this embodiment, film is biaxial optical film.

In one embodiment, the birefringence (" Δ n ") that film is measured at wavelength 589nm be about 0.007- about 0.010.In one embodiment, the Δ n that film is measured at wavelength 589nm is about 0.008- about 0.010.In an embodiment In, the Δ n that the film is measured at wavelength 589nm is about 0.009- about 0.010.

In one embodiment, the percent haze of film is less than about 0.9.In one embodiment, the percent haze of film is small In about 0.8.In one embodiment, the percent haze of film is less than about 0.7.In one embodiment, the percent haze of film Less than about 0.6.In one embodiment, the percent haze of film is less than about 0.5.In one embodiment, the percentage mist of film Degree is less than 0.4.In one embodiment, the percent haze of film is less than about 0.3.In one embodiment, the percent haze of film Less than about 0.2.

In one embodiment, film is C+ film, C- film, A+ film or A- film.In one kind of this embodiment, film is C+ film. In one kind of this embodiment, film is C- film.In one kind of this embodiment, film is A+ film.The one of this embodiment In class, film is A- film.In one kind of this embodiment, film is A- film.

In one embodiment, film is C+ film, C- film, reversion A film or NRZ film.

It is C+ film in one kind of this embodiment.In a this kind of subclass, film measures flat at wavelength 589nm Face external delays (" R_th") divided by the thickness (" d ") of film in the range of about 20 0-.In a subclass of this subclass, film is What single shaft, twin shaft or 45 degree stretched.

In one kind of this embodiment, film is C- film.In a this kind of subclass, what film was measured at wavelength 589nm The slow (" R of planar epitaxial_th") divided by the thickness (" d ") of film in the range of 0 to about -12.In a subclass of this subclass, Film is uniaxial, twin shaft or 45 degree of stretchings.In a this kind of subclass, the planar epitaxial that film is measured at wavelength 589nm is slow (“R_th") divided by the thickness (" d ") of film in the range of 0 to about -17.In a subclass of this subclass, film be it is uniaxial, Twin shaft or 45 degree stretching.In a this kind of subclass, the slow (" R of the planar epitaxial that film is measured at wavelength 589nm_th") divided by The thickness (" d ") of film is in the range of -2 to about -17.In a subclass of this subclass, film is uniaxial, twin shaft or 45 What degree stretched.In a this kind of subclass, the slow (" R of the planar epitaxial that film is measured at wavelength 589nm_th") divided by the thickness of film (" d ") is in the range of -5 to about -17.In a subclass of this subclass, film is uniaxial, twin shaft or 45 degree of stretchings 's.

In one kind of this embodiment, film is reversion A film.In a this kind of subclass, film meets relationship R_e450/ R_e550 < 1 and R_e650/R_e550 > 1, wherein R_e450、R_e550 and R_e650 be to survey at wavelength 450nm, 550nm and 650nm respectively Delay in the plane of amount.In a subclass of this subclass, postpone in the plane for the film that film is measured at wavelength 589nm (“R_e") in the range of about 100nm- about 300nm.In a sub- subclass of this seed subclass, film is uniaxial, twin shaft Or 45 degree stretching.

In one kind of this embodiment, film is NRZ film.In a this kind of subclass, film meets relationship R_e450/R_e550< 1 and R_e650/R_e550 > 1, wherein R_e450、R_e550 and R_e650 are measured at wavelength 450nm, 550nm and 650nm respectively Delay in plane.In a subclass of this subclass, postpone (" R in the plane for the film that film is measured at wavelength 589nm_e") In In the range of about 100nm- about 300nm.In a sub- subclass of this seed subclass, what film was measured at wavelength 589nm The slow (" R of planar epitaxial_e") in the range of about 0nm to about -50nm.In the sub- subclass of a son of this seed subclass, Film is uniaxial, twin shaft or 45 degree of stretchings.

In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness (" d ") of film -50 To in the range of 50.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness (" d ") of film In the range of -50 to 0.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness of film (" d ") is in the range of 0-50.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness of film (" d ") is spent in the range of -20 to 20.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thDivided by film Thickness (" d ") in the range of -20 to 0.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thIt removes With the thickness (" d ") of film in the range of 0-20.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_th Divided by the thickness (" d ") of film in the range of -15 to 15.In one embodiment, film disclosed above is measured at wavelength 589nm R_thDivided by the thickness (" d ") of film in the range of -15 to 0.In one embodiment, film disclosed above is at wavelength 589nm The R of measurement_thDivided by the thickness (" d ") of film in the range of 0-15.In one embodiment, film disclosed above is in wavelength 589nm The R of lower measurement_thDivided by the thickness (" d ") of film in the range of -10 to 10.In one embodiment, film disclosed above is in wavelength The R measured under 589nm_thDivided by the thickness (" d ") of film in the range of -10 to 0.In one embodiment, film disclosed above exists The R measured under wavelength 589nm_thDivided by the thickness (" d ") of film in the range of 0-10.In one embodiment, film disclosed above R_thNm is in the range of -5 to 0.In one embodiment, the R of film disclosed above_thNm is in the range of -5 to 0.One In embodiment, R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness (" d ") of film in the range of 0-5.One In embodiment, R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness (" d ") of film in the range of -3 to 3.In In one embodiment, R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness (" d ") of film in the range of -3 to 0. In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness (" d ") of film in the range of 0-3. In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thRange divided by the thickness (" d ") of film -1 to 1 It is interior.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thModel divided by the thickness (" d ") of film -1 to 0 In enclosing.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness (" d ") of film in the model of 0-1 In enclosing.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thIt is arrived divided by the thickness (" d ") of film -0.5 In the range of 0.5.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness (" d ") of film In the range of -0.5 to 0.In one embodiment, the R that film disclosed above is measured at wavelength 589nm_thDivided by the thickness of film (" d ") is in the range of 0-0.5.

The thickness of any of above film can be in the range of about 120 μm of about 40-, in about 70 μm of model of about 40- In enclosing, or in the range of about 20 μm of about 5-.Thickness and average thickness are used interchangeably in this application.As herein It uses, " average thickness " should indicate at least average value of evenly spaced measurement three times of optical film thickness.

In various embodiments, additive --- such as plasticizer, stabilizer, UV absorbent, anti-caking agent, slipping agent (slip agent), lubricant, dyestuff, pigment, delay modifying agent etc. --- it can be with the region that is used to prepare above-mentioned optical film The cellulose esters mixing selectively replaced.The example of these additives can be in such as patent application publication US 2009/ 0050842, it finds in US2009/0054638 and No. US2009/0096962, the content of these patent documents is merged by reference In this.

Any of above optical film can be manufactured by solvent cast, melting extrusion, laminated or coating method.These steps It suddenly is well known in the art.Solvent cast, melting extrusion, laminated and coating method example can be in such as U.S. Patent applications It discloses and is found in US2009/0050842, US2009/0054638 and No. US2009/0096962, the content of these patent documents It is incorporated herein by reference.Be used to form the solvent cast of film, melting extrusion, laminated and coating method other example can be with In such as United States Patent (USP) 4592885 and No. 7172713 and patent application publication US 2005/0133953 and US2010/ It is found in No. 0055356, the content of these patent documents is incorporated herein by reference.

In order to help the cellulose esters replaced using regioselectivity as described herein to obtain desired R_eAnd R_thValue, film can To be stretched.By adjusting stretching condition, such as draft temperature, tension-type (uniaxial or twin shaft), draw ratio, preheating time With temperature and and stretch after annealing time and temperature, desired R may be implemented_eAnd R_th.Accurate stretching condition can depend on: The vitrifying of the concrete composition for the cellulose esters that regioselectivity replaces, the amount and type and concrete composition of plasticizer turns Temperature.Therefore specific stretching condition can be widely varied.In various embodiments, draft temperature can be big in about 160- In the range of about 210 DEG C.In addition, draw ratio can be about 1.3- on laterally (" TD ") based on being 1.0 on longitudinal (" MD ") About 2.0.Preheating time can be in the range of about 10- about 300 seconds, and preheating temperature can be identical as draft temperature.Afterwards Annealing time can be about 0- about 300 seconds, and after annealing temperature can about 40 DEG C of about 10- lower than draft temperature.Film thickness Degree may depend on the film thickness and stretching condition before stretching.After the stretch, film thickness may is that about 1 μm-about 500 μm, greatly About 5 μm-about 200 μm, or about 10 μm-about 120 μm.

Other than optical characteristics, the film of the cellulose esters preparation replaced by regioselectivity as described herein also has it His valuable feature.Many conventional cellulose esters for LCD display have relatively high hygroscopicity, relatively high suction The moist variation for influencing dimensional stability and the optical value for leading to film.The cellulose replaced by regioselectivity as described herein The film of ester preparation has low hygroscopicity, and the optical value of film changes very small under high humidity and high temperature.Therefore, in different implementation In example, the cellulose esters that regioselectivity replaces may include: less than the moisture of 2wt%, the moisture less than 1wt%, Huo Zhe little In the moisture of 0.5wt%.In other different embodiments, when at 60 DEG C, the storage of 100% relative humidity 240 hours, fiber The R of cellulose ester film_eVariation can be less than 4%, less than 1%, or less than 0.5%.

The cellulose esters that regioselectivity as described herein replaces is surprisingly heat-staple, this makes them in film Melting extrusion in be highly useful.Therefore, an aspect of of the present present invention is related to the cellulose that such regioselectivity replaces Ester: the cellulose esters in 330 DEG C, 340 DEG C or 350 DEG C of thermogravimetric analysis weight loss less than 10%.

As described above, optical film as described herein can be used in LCD.In particular, above-mentioned optical film may be used as LCD's Compensation film in polarizing film stacked body it is some or all of.As described above, polarizing film stacked body generally includes two intersections Polarizing film is set on each side of liquid crystal layer.Compensation film can be set between one in liquid crystal layer and polarizing film.At one or In multiple embodiments, above-mentioned single layer optical film can itself serve as the compensation film (that is, wave plate) in LCD.In such embodiment In, single layer optical film can be set between liquid crystal layer and a polarizing filter of LCD.In other embodiments, above-mentioned- A optical film can be used in the compensation film (that is, wave plate) of LCD.In such embodiments ,-A optical film can be set to extremely A few other optical film is adjacent, wherein such other optical film can be-C optical film.In other embodiments, on Stating+C optical film can be used in the compensation film (that is, wave plate) of LCD.In such embodiments ,+C optical film can be set to It is adjacent at least one other optical film, wherein such other optical film can be+A optical film.In any aforementioned reality It applies in example, the prepared LCD comprising optical film as described herein can be with plane conversion (" IPS ") mode operation.

Optical compensation films as described herein can be used in OLED.For example, QWP combines to form circle partially with linear polarizer Shake piece.When circular polarizing disk is placed in front of OLED device, it can reduce the environment light that OLED metal electrode is reflected to improve Quality, such as high contrast and low color displacement are watched, especially when QWP has close to ideal inverse dispersion (reverse It is even more so when dispersion).

Optical film as described herein can also be used in circular polarizing disk.In particular, single quarter-wave plate can be made Standby is the optical film comprising one or more aforementioned present invention, can be used for linearly polarized light being converted to circularly polarized light.This Aspect is for for three-dimensional (" the 3D ") glasses of circular polarization and/or 3D mediavisualizer --- such as TV (" 3D TV ") --- meeting It is especially valuable.Therefore, in one or more embodiments, single quarter-wave plate can be prepared as including above-mentioned Single layer optical film.In other different embodiments, single quarter-wave plate can be prepared as including above-mentioned-A light Learn film.Such quarter-wave plate can be applied to the glass of 3D TV, such as in the top of polarization stacked body.In addition, in this way Quarter-wave plate can be applied to the glass of 3D glasses.It, can be with Application Optics film, so that one in the case where 3D glasses Optical axis in a lens perpendicular to or be substantially perpendicular to the optical axises of another lens.It is in 3D glasses the result is that certain observations Polarization be blocked on a lens, but observed 3D optical effect will be brought by another lens.In different realities Example is applied, polarizing film that the quarter-wave plate comprising one or more above-mentioned optical films can be other at least one (can be with It is linear polarizer) it is used in connection with.

Any disclosed film can be introduced into multilayer film.The application further relates to a kind of multilayer film, which includes to appoint What film disclosed in the present application.

Method

A kind of method that the application discloses cellulose esters for preparing regioselectivity substitution.Total C2 of the cellulose esters With C3 degree of substitution (" (C2+C3) DS ") in the range of about 2.0 about 0-, C6 degree of substitution (" C6DS ") about 0- about In the range of 0.6.

This method comprises:

(1) in a suitable solvent by the trifluoroacetic anhydride of cellulose and the equivalent of about 1.4 equivalents-about 1.8 One or more first carboxylics of (trifluoroacetic anhydride, " TFAA ") and the equivalent of about 0.1 equivalent-about 0.8 Acid contacts in reaction medium,

Wherein the equivalent of TFAA and the first carboxylic acid is the total amount of the anhydroglucose unit based on cellulose.

Suitable solvent for this method is any such solvent, can be dissolved in the reaction or partly Dissolution original fibers element is formed by cellulose esters, to bring desired product.In an embodiment of this method, close Suitable solvent is trifluoroacetic acid.

It is derived from the first carboxylic acid or any acylated chemical combination to (C2+C3) DS and the C6DS acyl substituent to contribute The acyl substituent of object.

In an embodiment of this method, C6DS is less than 0.4.In an embodiment of this method, C6DS is less than 0.2.In an embodiment of this method, C6DS is less than 0.1.In an embodiment of this method, C6DS is less than 0.08.In In one embodiment of this method, C6DS is less than 0.06.In an embodiment of this method, C6DS is less than 0.04.This In one embodiment of method, C6DS is less than 0.02.

In an embodiment of this method, further includes: (2) one or more acyl donors of 0.1-2.0 equivalent are added, Wherein the equivalent of the acyl donor is the total amount of the anhydroglucose unit based on cellulose.In one kind of this embodiment, acyl group Donor is selected from the second carboxylic acid or acid anhydrides.In a this kind of subclass, acyl donor is the second carboxylic acid.In a this kind of subclass In, acyl donor is acid anhydrides.

In one kind of this embodiment, acyl donor is added after at least 50% the first carboxylic acid consumption.At this In one subclass of class, acyl donor is selected from the second carboxylic acid or acid anhydrides.In a subclass of this subclass, acyl donor is Dicarboxylic acids.In a seed subclass of this subclass, acyl donor is acid anhydrides.

In one kind of this embodiment, acyl donor is added after at least 80% the first carboxylic acid consumption.At this In one subclass of class, acyl donor is selected from the second carboxylic acid or acid anhydrides.In a subclass of this subclass, acyl donor is Dicarboxylic acids.In a subclass of this subclass, acyl donor is acid anhydrides.

In one kind of this embodiment, acyl donor is added after at least 90% the first carboxylic acid consumption.At this In one subclass of class, acyl donor is selected from the second carboxylic acid or acid anhydrides.In a subclass of this subclass, acyl donor is Dicarboxylic acids.In a subclass of this subclass, acyl donor is acid anhydrides.

In an embodiment of this method, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") big In the range of about 5000Da- about 250000Da.In an embodiment of this method, the cellulose esters of regioselectivity substitution Weight average molecular weight (" M_w") in the range of about 25000Da- about 250000Da.In an embodiment of this method, The weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") in the range of about 50000Da- about 250000Da. In an embodiment of this method, the weight average molecular weight (" M for the cellulose esters that regioselectivity replaces_w") about In the range of 80000Da- about 250000Da.In an embodiment of this method, the cellulose esters of regioselectivity substitution Weight average molecular weight (" M_w") in the range of about 100000Da- about 250000Da.

In an embodiment of this method, the first carboxylic acid is R¹- COOH,

Wherein R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, Wherein the aryl is unsubstituted or with 1-6 R²What group replaced；Alternatively, 5-20 unit's heteroaryl, contains and independently selects From 1-3 hetero atom of oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R³What group replaced,

Wherein R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro, and

Wherein R³Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.

In an embodiment of this method, the second carboxylic acid is R¹- COOH,

Wherein R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, Wherein the aryl is unsubstituted or with 1-6 R²What group replaced；Alternatively, 5-20 unit's heteroaryl, contains and independently selects From 1-3 hetero atom of oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R³What group replaced,

Wherein R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro, and

Wherein R³Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.

In an embodiment of this method, cellulose is softwood cellulose, hardwood cellulose, lint cellulose or micro- Crystalline cellulose.In an embodiment of this method, cellulose is Placetate F cellulose.

In an embodiment of this method, reaction medium set temperature is about 20 DEG C-about 80 DEG C of range.At this In one kind of kind embodiment, reaction medium set temperature is about 35 DEG C-about 75 DEG C of range.The one of this embodiment example In class, reaction medium set temperature is about 0 DEG C-about 20 DEG C of range.In one kind of this embodiment example, reaction medium Set temperature is about 30 DEG C-about 50 DEG C of range.In one kind of this embodiment example, reaction medium set temperature is big About 50 DEG C-about 80 DEG C of range.

This application discloses a kind of method of cellulose esters for preparing regioselectivity substitution, the C2 of the cellulose esters replaces Degree (" C2DS ") is 0.01-1, C3 degree of substitution (" C3DS ") be 0.01-1 and C6 degree of substitution (" C6DS ") be about 0- about 0.1。

This includes:

(1) by the one of the trifluoroacetic anhydride (" TFAA ") and 0.1-2.0 equivalent of cellulose and about 5.0 equivalent of about 0.5- Kind or a variety of first acylating agents (first acylating agent, " FAA ") connect in the reaction medium with suitable solvent Touching, to be esterified at least part cellulose, the cellulose esters that thus production area selectively replaces,

The wherein total amount of anhydroglucose unit of the equivalent of TFAA and FAA based on the cellulose.

It is that derived from FAA or appointing for reaction medium is added to (C2+C3) DS and the C6DS acyl substituent to contribute The what acyl substituent of his acylated compounds.

Suitable solvent for this method is any such solvent, can be dissolved in the reaction or partly Dissolution original fibers element is formed by cellulose esters, to bring desired product.In an embodiment of this method, close Suitable solvent is trifluoroacetic acid.

In an embodiment of this method, C6DS is less than 0.4.In an embodiment of this method, C6DS is less than 0.2.In an embodiment of this method, C6DS is less than 0.1.In an embodiment of this method, C6DS is less than 0.08.In In one embodiment of this method, C6DS is less than 0.06.In an embodiment of this method, C6DS is less than 0.04.This In one embodiment of method, C6DS is less than 0.02.

In an embodiment of this method, the amount of TFAA is about 5.0 equivalent of 0.5 equivalent-.In this method In one embodiment, the equivalent of 0.5 equivalent of amount-about 3.0 of TFAA.In an embodiment of this method, the presence of TFAA Amount is about 2.0 equivalent of 0.5 equivalent-.In an embodiment of this method, the amount of TFAA is 1.0 equivalents-about 2.0 Equivalent.

In an embodiment of this method, one or more FAA are introduced after introducing TFAA.In this implementation In one kind of example, one or more FAA and TFAA are added while being dissolved in suitable solvent.In a this kind of son In class, suitable solvent is trifluoroacetic acid.In an embodiment of this method, one or more FAA be introduce TFAA it Preceding introducing.In one kind of this embodiment, one or more FAA and TFAA are added while being dissolved in suitable solvent Enter.In a this kind of subclass, suitable solvent is trifluoroacetic acid.It is one or more in an embodiment of this method FAA and TFAA are introduced simultaneously.In one kind of this embodiment, one or more FAA and TFAA are to be dissolved in properly Solvent while be added.In a this kind of subclass, suitable solvent is trifluoroacetic acid.

In an embodiment of this method, FAA is selected from acid anhydrides or acid halide (acid halide).In this side In one embodiment of method, FAA is selected from symmetric anhydride or mixed acid anhydride.In one kind of this embodiment, mixed acid anhydride be It is generated in reaction medium by the way that carboxylic acid is added.In an embodiment of this method, FAA is acid halide.

In one embodiment, FAA is R^1a-C(O)OC(O)-R^1b,

Wherein R^1aAnd R^1bIndependently selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) alkenyl；(C_3-7) cycloalkanes Base；(C_6-20) aryl, wherein the aryl is unsubstituted or with 1-6 R²What group replaced；Alternatively, 5-20 unit's heteroaryl, Containing the 1-3 hetero atom independently selected from oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R³Group Replace,

Wherein each R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen Element, (C_3-7) naphthenic base, (C_6-10) aryl or nitro, and

Wherein each R³Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen Element, (C_3-7) naphthenic base, (C_6-10) aryl or nitro.

In one embodiment, FAA is R^1a- C (O) X,

Wherein R¹It is selected from: (C_1-20) alkyl；Halogenated (C_1-20) alkyl；(C_2-20) alkenyl；(C_3-7) naphthenic base；(C_6-20) aryl, Wherein the aryl is unsubstituted or with 1-6 R²What group replaced；Alternatively, 5-20 unit's heteroaryl, contains and independently selects From 1-3 hetero atom of oxygen, sulphur and nitrogen, wherein the heteroaryl is unsubstituted or with 1-6 R³What group replaced,

Wherein each R²Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen Element, (C_3-7) naphthenic base, (C_6-10) aryl or nitro,

Wherein each R³Selected from (C_1-6) alkyl, halogenated (C_1-6) alkyl, (C_1-6) alkoxy, halogenated (C_1-6) alkoxy, halogen Element, (C_3-7) naphthenic base, (C_6-10) aryl or nitro, and

X is chlorine, bromine or iodine.

In an embodiment of this method, cellulose is hardwood cellulose, softwood cellulose, lint cellulose or micro- Crystalline cellulose.In an embodiment of this method, cellulose is Placetate F cellulose.

In an embodiment of this method, reaction medium set temperature is about 20 DEG C-about 80 DEG C of range.At this In one kind of kind embodiment, reaction medium set temperature is about 35 DEG C-about 75 DEG C of range.In one kind of this embodiment In, reaction medium set temperature is about 0 DEG C-about 20 DEG C of range.In one kind of this embodiment, reaction medium setting Temperature is about 30 DEG C-about 50 DEG C of range.In one kind of this embodiment, reaction medium set temperature is about 50 DEG C-about 80 DEG C of range.

A kind of method that the application discloses cellulose esters for preparing regioselectivity substitution.

This method comprises:

(1) by the trifluoroacetic anhydride (" TFAA ") of cellulose and 0.5-5.0 equivalent and 0.1-2.0 equivalent is one or more First acylating agent (" FAA ") contacts in the first reaction medium with the first suitable solvent, at least part of to be esterified Thus the cellulose produces the cellulose esters that medium regioselectivity replaces, the C2 degree of substitution (" C2DS ") of the cellulose esters It is 0.01-1, C3 degree of substitution (" C3DS ") is 0.01-1, and C6 degree of substitution (" C6DS ") is 0- about 0.1,

Wherein the equivalent of TFAA and FAA is the total amount of the anhydroglucose unit based on cellulose,

(2) cellulose esters (the intermediate regioselectively that the medium regioselectivity replaces is separated Substituted cellulose ester, " IRSCE "), and

(3) the second one or more acyls of the cellulose esters for replacing the medium regioselectivity and 0.1-2.0 equivalent Agent (second acylating agent, " SAA ") contacts in the second reaction medium with the second suitable solvent,

Wherein the equivalent of SAA is the total amount of the anhydroglucose unit based on IRSCE.

It is that derived from FAA or the first reaction medium is added to (C2+C3) DS and the C6DS acyl substituent to contribute Any acylated compounds acyl substituent.

The first suitable solvent for this method is any such solvent, can be dissolved in the reaction or portion Divide the cellulose esters of ground dissolution original fibers element or formation, to bring desired product.In an embodiment of this method, First suitable solvent is trifluoroacetic acid.

The second suitable solvent for this method is any such solvent, can be dissolved in the reaction or portion Divide ground dissolution original fibers element or be formed by cellulose esters, and it is inert for the reaction.In this method An embodiment in, the second suitable solvent is selected from: methyl ethyl ketone, tetrahydrofuran, dimethyl sulfoxide, 1,3- dimethyl -2- imidazoles Quinoline ketone, dimethyl acetamide, dioxane, dimethylformamide, ethyl acetate, butyl acetate, chloroform, pyridine or two Chloromethanes.

In an embodiment of this method, the first suitable solvent is trifluoroacetic acid, and the second suitable solvent is selected from first Ethyl ketone, tetrahydrofuran, dimethyl sulfoxide, 1,3- dimethyl-2-imidazolinone, dimethyl acetamide, dioxane, dimethyl methyl Amide, ethyl acetate, butyl acetate, chloroform, pyridine or methylene chloride.

In an embodiment of this method, C6DS is less than 0.08.In an embodiment of this method, C6DS is less than 0.06.In an embodiment of this method, C6DS is less than 0.04.In an embodiment of this method, C6DS is less than 0.02.

In an embodiment of this method, the amount of TFAA is about 8.0 equivalent of 0.5 equivalent-.In this method In one embodiment, the amount of TFAA is about 6.0 equivalent of 0.5 equivalent-.In an embodiment of this method, TFAA's is deposited It is about 4.0 equivalent of 0.5 equivalent-in amount.In an embodiment of this method, the amount of TFAA be 0.5 equivalent-about 3.0 equivalent.In one embodiment, the amount of TFAA is about 2.0 equivalent of 0.5 equivalent-.In an embodiment of this method In, the amount of TFAA is about 2.0 equivalent of 1.0 equivalents-.

In an embodiment of this method, one or more FAA are introduced after being introduced into the TFAA in TFA.In In one embodiment of this method, one or more FAA are introduced before being introduced into the TFAA in TFA.In this method In one embodiment, one or more FAA and the TFAA in TFA are introduced simultaneously.

In an embodiment of this method, FAA is selected from symmetric anhydride or mixed acid anhydride.In an implementation of this method In example, the FAA is acid halide.

In an embodiment of this method, cellulose is hardwood cellulose, softwood cellulose, lint cellulose or micro- Crystalline cellulose.In an embodiment of this method, cellulose is Placetate F cellulose.

In an embodiment of this method, the first reaction medium set temperature is about 20 DEG C-about 80 DEG C of range. In one kind of this embodiment, the first reaction medium set temperature is about 35 DEG C-about 75 DEG C of range.In this implementation In one kind of example, the first reaction medium set temperature is about 0 DEG C-about 20 DEG C of range.In one kind of this embodiment, First reaction medium set temperature is about 30 DEG C-about 50 DEG C of range.In one kind of this embodiment, the first reaction is situated between Matter set temperature is about 50 DEG C-about 80 DEG C of range.

In an embodiment of this method, the second reaction medium set temperature is about 20 DEG C-about 80 DEG C of range. In one kind of this embodiment, the second reaction medium set temperature is about 35 DEG C-about 75 DEG C of range.In this implementation In one kind of example, the second reaction medium set temperature is about 0 DEG C-about 20 DEG C of range.In one kind of this embodiment, Second reaction medium set temperature is about 30 DEG C-about 50 DEG C of range.In one kind of this embodiment, the second reaction is situated between Matter set temperature is about 50 DEG C-about 80 DEG C of range.