阅读说明：本技术 一种防治股骨头坏死中药组合物及其制备方法 (A kind of anti-treating caput femoris necrosis Chinese medicine composition and preparation method thereof ) 是由 邵海滨 罗永仁 吕昪弢 其他发明人请求不公开姓名 于 2018-05-27 设计创作，主要内容包括：本发明公开了一种防治股骨头坏死中药,它是以木豆叶、鸡血藤、黄芪、巴戟天、仙灵脾为原料,根据每味中药的不同特性,分别粉碎后经过预处理后,按比例配制,再经灭菌加蜂蜜制成丸剂。本发明产品组合及制作方法独特,治疗效果显著。(The invention discloses a kind of anti-treating caput femoris necrosis Chinese medicines, it is using cajan leaf, Caulis Spatholobi, Radix Astragali, Morinda officinalis, HERBA EPIMEDII as raw material, according to the different characteristics of every taste Chinese medicine, after crushing respectively after pretreatment, it prepares in proportion, then pill is made in sterilized plus honey.Product of the present invention combination and production method are unique, and therapeutic effect is significant.)

1. a kind of anti-treating caput femoris necrosis Chinese medicine, it is characterised in that it is the medicine made of the Chinese medicine material of following weight proportion Agent: cajan leaf 20 ~ 30, Caulis Spatholobi 20 ~ 30, Radix Astragali 10 ~ 20, Morinda officinalis 10 ~ 20, HERBA EPIMEDII 10 ~ 20.

2. anti-treating caput femoris necrosis Chinese medicine according to claim 1, wherein the weight proportion of each raw material is: cajan leaf 22 ~ 28, Caulis Spatholobi 22 ~ 28, Radix Astragali 13 ~ 17, Morinda officinalis 13 ~ 17, HERBA EPIMEDII 13 ~ 18.

3. anti-treating caput femoris necrosis Chinese medicine according to claim 1, wherein the weight proportion of each raw material is: cajan leaf 25 , Caulis Spatholobi 25, Radix Astragali 15, Morinda officinalis 16, HERBA EPIMEDII 15.

4. anti-treating caput femoris necrosis Chinese medicine according to claim 1,2 or 3, it is characterised in that described medicament is pill.

5. the preparation method of anti-treating caput femoris necrosis Chinese medicine described in claim 4, it is characterised in that: take cajan leaf, Caulis Spatholobi, Huang Stilbene, Morinda officinalis, HERBA EPIMEDII drying and crushing to 120 mesh fine powders, after above-mentioned whole pulvis components are mixed mixing in the ratio, Thermalization, sterilization treatment 10 ~ 30 minutes are carried out at a temperature of 100 DEG C ~ 110 DEG C, add honey that pill is made.

6. the preparation method of anti-treating caput femoris necrosis Chinese medicine according to claim 5, thermalization disinfecting action therein is to adopt Cooled down with step type and cure sterilizing, temperature is rapidly brought up to 110 DEG C, then segmentation drops to 100 DEG C, and curing sterilization time is 10 ~ 30 minutes.

7. the preparation method of anti-treating caput femoris necrosis Chinese medicine according to claim 6, curing disinfecting action therein be by The fine powder mixed keeps the temperature 10 minutes at 110 DEG C, then cools to 105 DEG C again and maintains 5 minutes, then cools to 100 DEG C of holdings 15 minutes.

Technical field

The present invention relates to a kind of anti-treating caput femoris necrosis Chinese medicine compositions and preparation method thereof, specifically with Chinese herbal medicine For the pill of raw material preparation, the invention further relates to the preparation methods of the Chinese medicine.

Background technique

Femoral head necrosis is the common frdquently encountered disease for seriously endangering human health.Current caput femoris necrosis patient in the world More than million people, last year China is average to suffer from caput femoris necrosis patient hundreds of people daily: the mankind invented drug before 3000 Since, antibiotic was had found before 200 years, human diseases are with regard to more complicated, more, it more difficult to control.Many chronic diseases, immune system are disorderly Random disease, all abuse with drug and antibiotic have very big relationship.The drug resistance of people is stronger.People is just more difficult to defeat the serious illness.And stock Head necrosis disease naturally also has its natural enemy.

Medical science and technology is very flourishing at present, and countries in the world put into countless financial resource and material resource and remove Research of Medical, but to absolutely mostly Several chronic diseases is helpless.

When immune system decline, it is easy to suffer from femoral head necrosis.If will suffer from over time femoral head necrosis we The constant killer cell in patient body can be allowed to become strong, rejuvenated, tackling femoral head necrosis is simple thing.So femur People can namely autoimmunity cell-constant killer cell (NK cell) be bad to tackle femoral head on one's own account for head necrotic disease Dead disease.Best treating caput femoris necrosis medicine is the immune system of oneself, immunocyte, my immune system in the world (natural killer immunocyte) can cure femoral head necrosis.

Cell activation solution:

Cell is the basic unit of vital movement.Known all biologies in addition to virus are made of cell, but virus is raw Life activity must could also embody in cell.In general, most microorganisms such as bacterium and protozoan are by one Cell composition, i.e. unicellular organism；Higher plant and higher mammal are then multicellular organisms.Cell can be divided into two classes: protokaryon is thin Born of the same parents, eukaryocyte.

Cytosis: basic unit of the cell as metabolism and function executes and completes the various specific of living organism Function cell there is matter transportation, energy conversion, information transduction, cell recognition, cell to support and movement and cell dissociation and anti- The functions such as imperial；

Erythrocyte: there is the function of carrying oxygen；

Nerve cell: it is excited there is conduction；

Lymphocyte: play the role of immune；

Phagocyte in body fluid: play the role of eliminating antigen；

Myocyte: there is movement；

The mesophyll cell of plant: it can carry out hanging photosynthesis synthesis of organic substance；

Stem cell: neoblast is differentiated；

Epidermal cell: there is protective tissue；

Retina cell: there is photosensitization.

Two kinds of reasons of cell disorders:

1, malnutritive (cell cannot get its requirement): repair, replicating cell when the raw material that needs it is not pair or insufficient；Appoint How a kind of shortage of human nutrition can all cause uncomfortable or even disease generation！

2, toxin invasion (cell is poisoned by its unwanted thing): bacterium, virus are also by that could hurt after generating toxin Evil body!

In short, cell health, human body is just healthy.

Cell activation solution:

1, nutrient required for cell is supplemented, cellular energy is improved, accelerates cell repair and regeneration

2, toxin is effectively excluded, body burden is mitigated

The important meaning of cell activation is that the influence for " into " and " out ", the realization of true health are the complete of " into " and " out " U.S.A is reached.

Into --- --- --- promotes nutrient absorption,

--- the exclusion of --- --- acceleration toxin out.

Summary of the invention

Having the purpose of the present invention is to provide one kind improves high blood coagulation state, dredging microcirculation, enhancing immunity of organism Power has the Chinese medicine of prevention and treatment femoral head necrosis.

It is a further object of the present invention to provide the preparation methods of the prevention and treatment femoral head necrosis Chinese medicine.

Solution of the invention is

Based on motherland's medicine to femoral head necrosis and its pathogenetic understanding and principle of reatment, with reference to modern pharmacological research at Just, from motherland's medicine treasure-house, filter out nourishing kidney-yin, tonifying Qi void, Removing Blood Stasis, it is pure and impure let out, that righting reinforcing, herbal cuisine are homologous is natural Food plant medicine skims the cream off milk by theory of traditional Chinese medical science prescription, plays it and promotes to improve high blood coagulation state, dredging microcirculation, increases Strong immunity of organisms has prevention and treatment femoral head necrosis effect.

Chinese medicine of the present invention is made of following component (dosage is parts by weight):

Cajan leaf 20 ~ 30, Caulis Spatholobi 20 ~ 30, Radix Astragali 10 ~ 20, Morinda officinalis 10 ~ 20, HERBA EPIMEDII 10 ~ 20.

As preferred: the weight proportion of each raw material is: cajan leaf 22 ~ 28, Caulis Spatholobi 22 ~ 28, Radix Astragali 13 ~ 17, Morinda offcinalis How Its 13 ~ 17, HERBA EPIMEDII 13 ~ 18.

As preferred: the weight proportion of each raw material is: cajan leaf 25, Caulis Spatholobi 25, Radix Astragali 15, Morinda officinalis 16, celestial spirit Spleen 15.

As preferred: the prevention and treatment femoral head necrosis Chinese medicine, it is characterised in that described medicament is pill.

It is described prevention and treatment femoral head necrosis Chinese medicine preparation method, it is characterised in that: take cajan leaf, Caulis Spatholobi, Radix Astragali, bar Halberd day, HERBA EPIMEDII drying and crushing to 120 mesh fine powders, after above-mentioned whole pulvis components are mixed mixing in the ratio, 100 DEG C ~ 110 DEG C at a temperature of carry out thermalization, sterilization treatment 10 ~ 30 minutes, add honey that pill is made.

The preparation method of the prevention and treatment femoral head necrosis Chinese medicine, thermalization disinfecting action therein are using piece-wise step Temperature, is rapidly brought up to 110 DEG C by formula cooling curing sterilizing, and then segmentation drops to 100 DEG C, and curing sterilization time is 10 ~ 30 minutes.

The preparation method of the prevention and treatment femoral head necrosis Chinese medicine, curing disinfecting action therein is thin by what is mixed Powder keeps the temperature 10 minutes at 110 DEG C, then cools to 105 DEG C again and maintains 5 minutes, then cools to 100 DEG C and kept for 15 minutes.

Cajan leaf: nature and flavor: light;It is flat;It is slightly poisonous, channel tropism: the heart channel of Hang-Shaoyin, major function: removing toxicity for detumescence.Main chickenpox in children, carbuncle swells Sore.

Cajan leaf, Chinese medicine name.For the cauline leaf of pulse family pigeonpea platymiscium pigeonpea Cajanus cajan(Linn.) Millsp.. There is cultivation on plant pigeonpea, the ground such as Zhejiang, Fujian, Taiwan, Guangdong, Guangxi, Sichuan, Guizhou, Yunnan.With the efficacy of removing toxicity for detumescence Effect.Cure mainly chickenpox in children, carbuncle sore tumefacting virus.

Pharmacological action 1 promotes growth of marrow mesenchyme stem cell.

2, prevention and treatment osteoporosis effect.

3, cerebral ischemia, anoxia-induced apoptosis effect are protected.

4, reducing blood lipid and norcholesterol effect.

5, estrogen-like action.

6, there is inhibiting effect to acrothesium floccosum.

Caulis Spatholobi: for pulse family, Angiospermae, Dicotyledoneae, the nickname of the various plants such as Papilionaceae.[1] Evergreen woody climber, hairless, shoot dirty-green, base portion have harbored several pieces of triangular shape perulas.

It is born in 1800 meters of woodss below of height above sea level.[2] it is distributed in the Yunnan west and south (Baoshan, Fengqing, Lincang, honest and just horse), wide West, Burma northeast also have.[2]

Seed is medicinal, there is nourishing liver and kidney, benefiting male body essence and invigorating sex functions, the function of antidiarrheal.Efficacy effect: root and stem are Yunnan Caulis Spatholobi

It is medicinal, promoting circulation of blood and enriching blood, clearing and activating the channels and collaterals.

1. the effect of pair hemopoietic system

2. the effect of pair blood coagulation, fibrinolytic

3. inhibiting heart and the effect of reducing blood pressure

4. anti-treating caput femoris necrosis effect

5. the adjusting of pair lipid-metabolism

Caulis Spatholobi dietary function:

It is Caulis Spatholobi bitter but slightly sweet taste, warm-natured, return liver, the heart, kidney channel;Color red blood, quality moistening and dispersing;With activating blood and relaxing tendons, nourishing blood for regulating menstruation The effect of;

Rheumatic arthralgia is cured mainly, numb in every limb, quadriplegia, irregular menstruation, blockage of menstruation, dysmenorrhea, menostasis, leukopenia.

The guidance of Caulis Spatholobi way: 1. can treat waist and knee joints pain, rheumatic arthralgia, extremity numbness caused by rheumatism.

2. can be used for irregular menstruation, menostasis, dysmenorrhea.

Radix Astragali: Chinese medicine name.This product is the root of leguminous mongolian scutellaria.Spring, autumn excavation, remove soil, fibrous root and Root head shines to 6 seventy percent dry, and reason is dried after directly lashing.Major function are as follows: invigorating qi for strengthening superficies, pus draining and toxin expelling, diuresis, myogenic.For The long disunion of deficiency of vital energy and acking in strength, rush down prolapse of the anus for a long time, spontaneous perspiration, oedema, sub-official prolapses, chronic rephrilis protinuria, diabetes, the open sore part.It is warm-natured, It is sweet in flavor.Invigorating qi for strengthening superficies, pus draining and toxin expelling, diuresis, myogenic.For deficiency of vital energy and acking in strength, rush down prolapse of the anus for a long time, spontaneous perspiration, oedema, sub-official prolapses, slow Property nephritic proteinuria, diabetes, the long disunion of the open sore part.Calycosin containing flavones ingredient (calycosin), hydroxyl -9 3-, 10- dimethoxy red sandalwood alkane, also (astragaloside I, V, III) containing astragalus saponin I, V, III.

Morinda officinalis: Morinda officinalis (scientific name: Morinda officinalis How) is dicotyledon Rubiaceae, long by 3 ~ 13cm, wide 1.5 ~ 5cm, front end is short tapering, base portion obtuse or circle.The dry root of Morinda officinalis, root are in oblate cylindricality, slightly curved song.

Main product is in Guangdong, Guangxi and other places.Medicinal plant, cure mainly impotence and seminal emission, uterus cold infertile, irregular menstruation, abdomen crymodynia, Rheumatic arthralgia, muscles and bones impotence.Root contains anthraquinone component: Rubiadin (rubiadin), Rubiadin 1-methylether (rubiadin-1-methyl ether), Physcion (physcion), 2- hydroxyl methylol anthraquinone (2-hydroxy-3- Hydrox-ymethylanthraquinone), 1- hydroxy-anthraquione (1-hydroxyanthraquinone), 1- hydroxy-2-methyl Anthraquinone (1-hydroxy-2-methyl anthraquinone), 1,6- dihydroxy -2,4- dimethoxy anthraquinone (1,6- Dihydroxy-2,4-dimethoxyan-thraquinone), 1,6- dihydroxy -2- methoxy anthraquinone (1,6-dihydroxy- 2-methoxyanthraquinone), 2-methylanthraquinone (2-methylanthraqui-none), also ingredient containing iridoid； Monotropein (Monotropein), four acetyl asperulosides (asperuloside teTCMLIBaacetate).Contain grape again Sugared (glucose), mannose (mannose), cupreol (β-sitosterol), palmitinic acid (palmitic acid).Dimension life Element (vitamin) C, nonadecane (nonadecane), 24- ethyl cholesterine (24-ethyl cholesterol).Root skin containing zinc, 23 kinds of elements such as manganese, iron, chromium.

HERBA EPIMEDII: HERBA EPIMEDII be called just before, Herba Epimedii, celestial spirit adjoin, Herba Epimedii, thousand liang of gold, dry chicken muscle, coptis ancestral, three Nine leaves etc., HERBA EPIMEDII have the effect of tonifying kidney and strengthening yang, dispelling wind and eliminating dampness, strengthening the muscles and bones, and HERBA EPIMEDII has treatment impotence and seminal emission, void cold not It educates, the effect that frequent micturition incontinence, dyspnea and cough due to deficiency of the kidney, soreness and weakness of waist and knees, rheumatic arthralgia, hemiplegia, four limbs are meciless, the deficiency of Yin and mutually fiery movability Person's wood taboo takes HERBA EPIMEDII.Smell is pungent, warm, nontoxic.Li Mingzhen is said: " Herba Epimedii gas sweet in flavor is fragrant, warm-natured not tremble with fear, can strengthening the essence Gas.... insufficiency of kidney-YANG person preferably it ".

The traditional chinese medicine composition of the invention result in clinical application shows, has the advantage that:

1. most natural edible-plant medicines for selecting herbal cuisine homologous of the invention are raw material, each component meets pharmaceutical control and administration law regulation.It utilizes The comprehensive function of each taste Chinese medicine prevents and treats femoral head necrosis, non-toxic to humans without chemical sweetener.

2. the present invention is without decocting, no bitterness sense is full of nutrition, convenient to take, meets state food health law.

3. alleviating or eliminating other symptoms using the prevention and treatment femoral head necrosis Chinese medicine with can dramatically, enhance exempting from for body Epidemic disease power achievees the purpose that cure femoral head necrosis.

To show Chinese medicine of the present invention to the therapeutic effect of prevention and treatment femoral head necrosis, the present invention is seen through 56 system clinics It examines, observes object, wherein male 24, female 32, the age 35 ~ 57 years old.It is inspected periodically using same procedure, treatment phase 5 ~ 8 months, 1 month is 1 course for the treatment of, totally 5 ~ 8 courses for the treatment of, and the observation period 2 months, 1 month was 1 course for the treatment of, totally 2 courses for the treatment of.

Instructions of taking: the Chinese medicine of embodiment 2, takes daily 3 times by 10 grams/times, and warm water is swallowed after meal, duration of medication dieting: Peppery, sour, pungent, fish, seafood, mutton, dog meats etc..

Specific embodiment