阅读说明：本技术 一种气压平衡结构及具有其的定量采样加注器 (Air pressure balance structure and quantitative sampling filler with same ) 是由 席秋子 邱华星 于 2021-08-03 设计创作，主要内容包括：本发明公开了一种气压平衡结构及具有其的定量采样加注器,包括：外管,其至少部分限定形成位于其内部的外管腔,所述外管在其一端敞开形成与所述外管腔相连通的插接口；隔断组件,其设于所述外管腔中并在其周向与所述外管腔的侧壁相贴合以将所述外管腔沿轴向依次分隔成混液腔与导引腔；以及对接管,至少部分所述对接管通过所述插接口插接入所述导引腔中；其中,所述隔断组件中开设有连通所述混液腔与导引腔的通气管道；当所述对接管至少部分插接入所述导引腔时,对接管的至少部分外周与所述导引腔的侧壁形成有间隙通路。根据本发明,其能够平衡采样加注器的混液管的内外气压,防止由于气压不一致导致的吸液困难的现象发生。(The invention discloses an air pressure balance structure and a quantitative sampling filler with the same, wherein the air pressure balance structure comprises: an outer tube at least partially defining an outer tube cavity therein, the outer tube being open at one end thereof forming a socket in communication with the outer tube cavity; the partition assembly is arranged in the outer tube cavity and is attached to the side wall of the outer tube cavity in the circumferential direction of the partition assembly so as to sequentially divide the outer tube cavity into a liquid mixing cavity and a guide cavity along the axial direction; at least part of the butt joint pipe is inserted into the guide cavity through the insertion port; wherein, an air duct for communicating the liquid mixing cavity and the guide cavity is arranged in the partition component; when the butt joint pipe is at least partially inserted into the guide cavity, a clearance passage is formed between at least part of the periphery of the butt joint pipe and the side wall of the guide cavity. According to the present invention, it is possible to balance the internal and external air pressures of the liquid mixing tube of the sampling injector, thereby preventing the occurrence of a phenomenon in which liquid suction is difficult due to inconsistency in air pressure.)

1. An air pressure equalizing structure, comprising:

an outer tube (12) at least partially defining an outer tube lumen (1213) therein, the outer tube (12) being open at one end thereof forming a socket (1212) in communication with the outer tube lumen (1213);

the partition assembly is arranged in the outer tube cavity (1213) and is attached to the side wall of the outer tube cavity in the circumferential direction of the partition assembly so as to sequentially divide the outer tube cavity (1213) into a liquid mixing cavity (1221) and a guide cavity (1211) along the axial direction; and

a docking tube (13), at least part of the docking tube (13) being inserted into the guide chamber (1211) through the insertion opening (1212);

wherein, an air duct which is communicated with the liquid mixing cavity (1221) and the guide cavity (1211) is arranged in the partition component; when the butt joint pipe (13) is at least partially inserted into the guide cavity (1211), a clearance passage is formed between at least part of the periphery of the butt joint pipe (13) and the side wall of the guide cavity (1211), so that the guide cavity (1211) is communicated with the outside through the clearance passage.

2. The air pressure balancing structure of claim 1, wherein the clearance passage is at least one ventilation groove (136) opened in an outer surface of the docking pipe (13), the ventilation groove (136) extending from the docking port (132) along the outer surface of the docking pipe (13) toward the other end of the docking pipe (13).

3. The air pressure equalizing structure of claim 1 or 2, wherein the clearance passage is at least one vent groove opening in a side wall of the guide chamber (1211), the vent groove extending from the partition assembly along the side wall of the guide chamber (1211) toward the plug port (1212).

4. The air pressure balancing structure according to claim 1 or 2, wherein the outer surface of the side wall (134) of the butt joint pipe (13) is formed with a ring of circumferentially arranged sealing slopes (135), and the outer diameter of the sealing slopes (135) gradually increases in a direction away from the butt joint opening (132) such that the outer surface of the sealing slopes (135) forms an included angle α with the axis of the butt joint pipe (13).

5. The air pressure balance structure of claim 4, wherein the included angle α is 3 ° to 10 °; the sealing ramp (135) is at least partially made of a soft and/or pliable material, which enables the sealing ramp (135) to seal the opening of the guide tube (121) when the guide tube (121) is fitted to the sealing ramp (135).

6. The air pressure balance structure of claim 4 wherein said air permeation groove (136) extends from said interface port (132) along the outer surface of the sidewall (134) of said interface tube (13) and terminates at said sealing ramp (135).

7. The air pressure balancing structure of claim 4, characterized in that the outer surface of the side wall (134) of the butt joint pipe (13) is formed with a ring of circumferentially arranged sealing rings (133), and the maximum outer diameter of the sealing ramp (135) terminates on the end face of the sealing rings (133).

8. The air pressure equalizing structure of claim 1 or 2, wherein the partition assembly comprises:

at least two partition units (1261) which are arranged coaxially and at intervals; and

at least one connecting unit (1263), each connecting unit (1263) axially connecting two adjacent partition units (1261);

wherein, the partition unit (1261) is provided with a riser vent (1262); the vent holes (1262) of any one of the partition units (1261) and the vent holes (1262) of the other partition units (1261) adjacent to the partition unit (1261) are arranged in an axially staggered manner.

9. A quantitative sampling doser characterized by comprising the air pressure balance structure as claimed in any one of claims 1 to 8.

Technical Field

The invention relates to the field of reagent titration detection, in particular to an air pressure balance structure and a quantitative sampling filler with the same.

Background

In a traditional detection and analysis process, a sample is usually collected first, then the sample is filled into a reagent or a buffer solution for reaction, and finally the liquid sample after reaction is transferred to a detection device for detection.

However, the existing sampling filler is often difficult to absorb liquid due to non-uniform air pressure inside and outside the liquid mixing pipe in the operation process due to overhigh integration level and unreasonable design.

In view of the above, it is necessary to develop a pressure balance structure and a quantitative sampling filler with the same to solve the above problems.

Disclosure of Invention

In order to overcome the problems of the reagent dripping equipment, the invention aims to provide an air pressure balance structure which can balance the internal and external air pressures of a liquid mixing pipe of a sampling injector and prevent the phenomenon of difficult liquid suction caused by inconsistent air pressures.

As for the air pressure balance structure, the air pressure balance structure of the present invention to solve the above technical problems includes:

an outer tube at least partially defining an outer tube cavity therein, the outer tube being open at one end thereof forming a socket in communication with the outer tube cavity;

the partition assembly is arranged in the outer tube cavity and is attached to the side wall of the outer tube cavity in the circumferential direction of the partition assembly so as to sequentially divide the outer tube cavity into a liquid mixing cavity and a guide cavity along the axial direction; and

the butt joint pipe, at least some said butt joint pipe is inserted into said guide cavity through said interface;

wherein, an air duct for communicating the liquid mixing cavity and the guide cavity is arranged in the partition component; when the butt joint pipe is at least partially inserted into the guide cavity, a clearance passage is formed between at least part of the periphery of the butt joint pipe and the side wall of the guide cavity, so that the guide cavity is communicated with the outside through the clearance passage.

Optionally, the clearance passage is at least one ventilation groove formed in the outer surface of the butt joint pipe, and the ventilation groove extends from the butt joint port toward the other end of the butt joint pipe along the outer surface of the butt joint pipe.

Optionally, the ventilation groove extends linearly along the axial direction of the butt joint pipe.

Optionally, the gas-permeable groove extends helically around the axis of the butt-joint tube.

Optionally, the ventilation slots extend in an undulating fashion around the axis of the butt-joint pipe.

Optionally, the clearance passage is at least one vent groove formed in a side wall of the guide cavity, and the vent groove extends from the partition assembly toward the insertion port along the side wall of the guide cavity.

Optionally, the outer surface of the sidewall of the butt-joint pipe is formed with a circle of sealing slopes arranged around, and the outer diameter of the sealing slopes gradually increases in a direction away from the butt-joint port so that the outer surface of the sealing slopes forms an included angle α with the axis of the butt-joint pipe.

Optionally, the included angle α is 3 to 10 degrees; the sealing ramp is at least partially made of a soft and/or pliable material, which enables the sealing ramp to seal the opening of the guide tube when the guide tube is fitted to the sealing ramp.

Optionally, the gas-permeable groove extends from the interface opening along the outer surface of the sidewall of the interface tube and terminates at the sealing ramp.

Optionally, the outer surface of the side wall of the butt joint pipe is formed with a ring of sealing rings arranged around, and the maximum outer diameter of the sealing slope is terminated on the end face of the sealing ring.

Optionally, the partition assembly includes:

at least two partition units which are coaxial and arranged at intervals; and

at least one connecting unit, wherein each connecting unit is used for axially connecting two adjacent partition units;

wherein, the partition unit is provided with an air hole; the air holes on any one partition unit and the air holes on other partition units adjacent to the partition unit are arranged in a staggered mode in the axial direction.

Accordingly, another object of the present invention is to provide a quantitative sampling filler capable of balancing the internal and external air pressures of a liquid mixing tube and preventing the liquid suction difficulty caused by the non-uniform air pressure.

In terms of the dust-gas separation method, the quantitative sampling filler of the present invention for solving the above technical problem includes any one of the above-described air pressure balance structures.

One of the above technical solutions has the following advantages or beneficial effects: because the internal and external air pressures of the liquid mixing pipe of the sampling filling device can be balanced, the phenomenon of difficult liquid suction caused by inconsistent air pressures is prevented.

Drawings

In order to more clearly illustrate the technical solution of the embodiments of the present invention, the drawings of the embodiments will be briefly described below, and it is apparent that the drawings in the following description relate only to some embodiments of the present invention and are not limiting thereof, wherein:

FIG. 1 is a perspective view of a quantitative sampling doser with an air pressure balancing structure according to one embodiment of the present invention;

FIG. 2 is a longitudinal cross-sectional view of a quantitative sampling doser with a pressure equalization structure according to one embodiment of the present invention;

FIG. 3 is a longitudinal cross-sectional view of a quantitative sampling doser with a pressure equalization structure according to one embodiment of the present invention, showing the explosion of the various components together;

fig. 4 is a perspective view of a quantitative sampling filler with a pressure balancing structure according to an embodiment of the present invention, in which a cap and a liquid mixing assembly are not shown.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

In the drawings, the shape and size may be exaggerated for clarity, and the same reference numerals will be used throughout the drawings to designate the same or similar components.

Unless defined otherwise, technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this invention belongs. The use of "first," "second," and similar terms in the description and claims of the present application do not denote any order, quantity, or importance, but rather the terms are used to distinguish one element from another. Also, the use of the terms "a," "an," or "the" and similar referents do not denote a limitation of quantity, but rather denote the presence of at least one. The word "comprise" or "comprises", and the like, means that the element or item listed before "comprises" or "comprising" covers the element or item listed after "comprising" or "comprises" and its equivalents, and does not exclude other elements or items. "upper", "lower", "left", "right", and the like are used merely to indicate relative positional relationships, and when the absolute position of the object being described is changed, the relative positional relationships may also be changed accordingly.

In the following description, terms such as center, thickness, height, length, front, back, rear, left, right, top, bottom, upper, lower, etc., are defined with respect to the configurations shown in the respective drawings, and in particular, "height" corresponds to a dimension from top to bottom, "width" corresponds to a dimension from left to right, "depth" corresponds to a dimension from front to rear, which are relative concepts, and thus may be varied accordingly depending on the position in which it is used, and thus these or other orientations should not be construed as limiting terms.

Terms concerning attachments, coupling and the like (e.g., "connected" and "attached") refer to a relationship wherein structures are secured or attached, either directly or indirectly, to one another through intervening structures, as well as both movable or rigid attachments or relationships, unless expressly described otherwise.

Example 1

Fig. 1 to 3 show embodiment 1 of the present invention, and in conjunction with the illustrations of fig. 1 to 2, it can be seen that the air pressure balance structure includes:

an outer tube 12 at least partially defining an outer tube lumen 1213 therein, the outer tube 12 being open at one end thereof forming a socket 1212 communicating with the outer tube lumen 1213;

the partition assembly is arranged in the outer tube cavity 1213 and is attached to the side wall of the outer tube cavity in the circumferential direction of the partition assembly so as to sequentially divide the outer tube cavity 1213 into a liquid mixing cavity 1221 and a guide cavity 1211 in the axial direction; and

an interface tube 13, at least a portion of the interface tube 13 being inserted into the guide cavity 1211 through the insertion port 1212;

wherein, an air duct for communicating the liquid mixing cavity 1221 with the guide cavity 1211 is arranged in the partition component; when the butt joint pipe 13 is at least partially inserted into the guide cavity 1211, a clearance passage is formed between at least a part of the periphery of the butt joint pipe 13 and the side wall of the guide cavity 1211, so that the guide cavity 1211 is communicated with the outside through the clearance passage.

Referring to fig. 4, the clearance passage is at least one ventilation groove 136 opened on the outer surface of the butt joint pipe 13, and the ventilation groove 136 extends from the butt joint port 132 toward the other end of the butt joint pipe 13 along the outer surface of the butt joint pipe 13. In the embodiment shown in fig. 4, the ventilation groove 136 extends linearly along the axial direction of the interface tube 13. In another embodiment, the gas-permeable slots 136 extend helically around the axis of the interface tube 13. In yet another embodiment, the ventilation slots 136 extend in an undulating fashion around the axis of the interface tube 13.

As a further improvement, the clearance passage is at least one ventilation groove opening on a side wall of the guide chamber 1211, which extends from the partition element along the side wall of the guide chamber 1211 towards the plug-in opening 1212.

Referring to fig. 2, the outer surface of the sidewall 134 of the butt joint pipe 13 is formed with a ring of circumferentially arranged sealing slopes 135, and the outer diameter of the sealing slopes 135 gradually increases in a direction away from the butt joint port 132 such that the outer surface of the sealing slopes 135 forms an included angle α with the axis of the butt joint pipe 13. The sealing ramp 135 is capable of sealing the opening of the plug interface 1212 when the docking tube 13 is progressively inserted into the guide lumen 1211 and eventually causes the sidewall of the guide lumen 1211 to mate to the sealing ramp 135.

Further, the included angle alpha is 3-10 degrees; the sealing ramp 135 is at least partially made of a soft and/or pliable material, which allows the sealing ramp 135 to seal the opening of the guide tube 121 when the guide tube 121 is mated to the sealing ramp 135.

Further, the venting groove 136 extends from the docking port 132 along the outer surface of the sidewall 134 of the docking tube 13 and terminates at the sealing ramp 135.

Further, the outer surface of the side wall 134 of the butt joint pipe 13 is formed with a ring of circumferentially arranged sealing rings 133, and the maximum outer diameter of the sealing slope 135 is terminated on the end surface of the sealing rings 133.

Referring to fig. 3 and 4, the partition assembly includes:

at least two partition units 1261 arranged coaxially and at intervals; and

at least one connecting unit 1263, each connecting unit 1263 axially connecting two adjacent partition units 1261;

wherein, the partition unit 1261 is provided with a vent 1262; the vent holes 1262 of any one of the partition units 1261 are axially staggered from the vent holes 1262 of the other partition units 1261 adjacent to the partition unit 1261.

The air holes 1262 can make the air pressures of the liquid mixing cavity 1221 and the guide cavity 1211 consistent, so that liquid can be conveniently sucked into the liquid mixing cavity 1221, and by adopting the structure, the liquid sprayed from the liquid mixing cavity in the imbibing process can be blocked outside the guide cavity 1211 under the blocking of the multiple partition units 1261 while the air pressures of the liquid mixing cavity 1221 and the guide cavity 1211 are consistent, so that the liquid sprayed from the liquid mixing cavity 1221 can not be polluted by other parts of the guide cavity and the inner tube 123, such as the guide cavity part and the butt joint pipe 13.

Example 2

Fig. 1 to 4 show embodiment 2 of the present invention, and embodiment 2 differs from embodiment 1 in that: disclosed is a quantitative sampling filler 1, comprising an inner tube 123, a capillary tube 124 and an air pressure balance structure, wherein the air pressure balance structure comprises:

an outer tube 12 at least partially defining an outer tube lumen 1213 therein, the outer tube 12 being open at one end thereof forming a socket 1212 communicating with the outer tube lumen 1213;

the partition assembly is arranged in the outer tube cavity 1213 and is attached to the side wall of the outer tube cavity in the circumferential direction of the partition assembly so as to sequentially divide the outer tube cavity 1213 into a liquid mixing cavity 1221 and a guide cavity 1211 in the axial direction; and

a docking pipe 13 at least partially defining a docking chamber 131 formed therein, one end of the docking pipe 13 being open to form a docking port 132 communicating with the docking chamber 131, at least a portion of the docking pipe 13 being inserted into the guide chamber 1211 through the insertion port 1212;

the inner tube 123 has a proximal end 126 and a distal end 1231, at least a portion of the inner tube 123 is installed in the guiding cavity 1211, and the proximal end 126 of the inner tube 123 seals off the end of the guiding cavity 1211 to separate the guiding cavity 1211 from the liquid mixing cavity 1221;

the capillary tube 124 extends from the distal end 1231 to the proximal end 126 along the axial direction inside the inner tube 123, and the liquid mixing chamber 1221 is communicated with the outside through the capillary tube 124;

an air duct for communicating the liquid mixing cavity 1221 with the guide cavity 1211 is arranged in the partition assembly; when the butt joint pipe 13 is at least partially inserted into the guide cavity 1211, a clearance passage is formed between at least part of the periphery of the butt joint pipe 13 and the side wall of the guide cavity 1211, so that the guide cavity 1211 is communicated with the outside through the clearance passage;

a liquid outlet 1222 communicated with the liquid mixing cavity 1221 is formed in the liquid mixing tube 122, and a cover 11 is selectively coupled to the liquid mixing tube 122 to selectively block the liquid outlet 1222;

in the embodiment shown in fig. 2, the guide tube 121 defines a guide chamber 1211 and the liquid mixing tube 122 defines a liquid mixing chamber 1221.

In use, the lid 11 firstly seals the liquid outlet 1222, the inner tube 123 is inserted into the sample cup so that the sample liquid in the sample cup is sucked by the capillary tube 124 and temporarily stored in the liquid mixing chamber 1221, and then the inner tube 123 is inserted into the buffer cup 14 so that the buffer liquid is flushed into the liquid mixing chamber 1221 along the capillary tube 124, and the buffer liquid and the sample are mixed in the flushing process. The quantitative sampling and filling device can be shaken up by hands or a shaking up device in order to mix the buffer solution and the sample more uniformly.

In an exemplary embodiment, the liquid mixing tube 122 is at least partially made of a soft and/or pliable material, which allows the volume of the liquid mixing chamber 1221 to be reduced accordingly after the liquid mixing tube 122 is squeezed. For example, the mixture tube 122 can be made of, but is not limited to, rubber and/or rubber-like materials, or can be of any construction and/or material so long as the mixture tube 122 functions as described herein.

After the mixture is uniform, the cover 11 is removed to expose the liquid outlet 1222, and the solution uniformly mixed in the liquid mixing cavity 1221 can be extruded out by pressing the liquid mixing tube 122 as required to achieve quantitative filling.

After the filling is completed, the cover 11 is fitted to the liquid mixing tube 122 to close the liquid outlet 1222 again, so as to prevent the liquid in the liquid mixing chamber 1221 from dropping out or prevent the inside of the liquid mixing chamber 1221 from being contaminated by the outside.

In practice, it is found that in the process of inserting the inner tube 123 into the buffer cup, because the buffer cup 14 lacks stable support and positioning, a slip phenomenon is easily caused between the inner tube 123 and the sealing film of the buffer cup 14, and finally the insertion success rate of the inner tube 123 is low, and meanwhile, the exposed inner tube 123 is also easily polluted to cause detection failure, and in order to solve the problem, the quantitative sampling and filling device 1 is further improved:

in the embodiment shown in fig. 2 and 3, the quantitative sampling and filling device 1 further includes a docking pipe 13 defining a docking cavity 131, one end of the docking pipe 13 is opened to form a docking port 132 communicated with the docking cavity 131, and the buffer cup 14 enters and exits the docking cavity 131 through the docking port 132.

The docking pipe 13 provides a receiving space and a supporting force for the buffer cup 14, and the distal end 1231 of the inner pipe 123 is gradually inserted into the docking cavity 131 through the docking port 132 and finally inserted into the buffer cup 14 under the guidance of the sidewall of the docking pipe 13.

Further, the inner tube 123 is spaced apart from the sidewall of the guide tube 121 to define an avoidance space between the inner tube 123 and the guide tube 121; when the inner tube 123 is inserted into the docking cavity 131, the sidewall 134 of the docking tube 13 is received by the escape space.

In practice, it is found that when the capillary suction tube 124 sucks the sample liquid or the buffer liquid, since the liquid mixing cavity 1221 is in a closed state, the volume of the liquid mixing cavity 1221 gradually decreases with the injection of the liquid, and finally the internal pressure of the liquid mixing cavity 1221 is higher than the external atmospheric pressure value, so that the subsequent sample liquid or buffer liquid cannot be sucked into the liquid mixing cavity 1221, and in order to solve the problem, the quantitative sampling and filling device 1 is further improved:

in the embodiment shown in fig. 2 and 3, the proximal end of the inner tube is a partition assembly comprising:

the proximal end 126 of the inner tube 123 is a partition assembly comprising:

at least two partition units 1261 arranged coaxially and at intervals; and

at least one connecting unit 1263, each connecting unit 1263 axially connecting two adjacent partition units 1261;

wherein, the partition unit 1261 is provided with a vent 1262; the vent holes 1262 of any one of the partition units 1261 are axially staggered from the vent holes 1262 of the other partition units 1261 adjacent to the partition unit 1261.

The air holes 1262 can ensure that the air pressures of the liquid mixing cavity 1221 and the guide cavity 1211 are consistent, so that liquid can be conveniently sucked into the liquid mixing cavity 1221, and by adopting the structure, the liquid sprayed from the liquid mixing cavity in the liquid suction process can be blocked outside the guide cavity 1211 under the blocking of the multiple partition units 1261 while the air pressures of the liquid mixing cavity 1221 and the guide cavity 1211 are consistent, so that the liquid sprayed from the liquid mixing cavity 1221 cannot be polluted by other parts of the guide cavity and the inner tube 123, such as the guide cavity part and the butt joint pipe 13.

Referring again to fig. 3, the distal end 1231 of the inner tube 123 is tapered such that it facilitates puncturing the closed membrane of the buffer cup 14 and into the buffer chamber 141.

As a further improvement, the bottom of the buffer chamber 141 is a contoured structure that conforms to the distal end 1231 of the inner tube 123. So that when the distal end 1231 of the inner tube 123 reaches the bottom of the buffer chamber 141, the outer surface of the distal end 1231 is attached to the bottom of the buffer chamber 141, and there is no space to accommodate the buffer, and the buffer is finally squeezed into the capillary tubing 124.

As a further improvement, a circle of liquid scraping rings 1232 are formed at the junction of the distal end 1231 of the inner tube 123 and the main body of the inner tube 123, and the outer diameter of the liquid scraping rings 1232 is larger than the inner diameter of the buffer liquid cavity 141.

In the illustrated embodiment, the outer diameter of the liquid scraping ring 1232 is 1.02 to 1.2 times the inner diameter of the buffer liquid chamber 141. The scraping ring 1232 is at least partially made of a soft and/or flexible material, such that during the insertion of the distal end 1231 of the inner tube 123 into the buffer chamber 141, the scraping ring 1232 can be pressed to tightly abut against the sidewall of the buffer chamber 141 to scrape off the buffer solution adhered to the sidewall of the buffer chamber 141.

Referring to fig. 3 again, the liquid outlet 1222 is opened at the end of the liquid mixing tube 122, a circle of mixed liquid guiding structure 125 is formed around the liquid outlet 1222 outside the liquid outlet 1222, a liquid guiding tube 1251 extending from the liquid outlet 1222 is arranged in the mixed liquid guiding structure 125 in an extending manner, and the liquid guiding tube 1251 is funnel-shaped from inside to outside. Mixed liquor is derived structure 125 and can be to mixed liquor titration or filling direction carry out the directional guide, prevent to appear the uncontrollable problem of liquid drop direction among the titration process.

Referring again to fig. 2 and 3, a profile fitting groove 111 corresponding to the mixed liquid discharge structure 125 is formed in the cover 11, a blocking terminal 112 corresponding to the liquid guide path 1251 is formed at the bottom of the profile fitting groove 111, and the blocking terminal 112 blocks the liquid guide path 1251 when the cover 11 is fitted to the mixed liquid discharge structure 125.

As a further improvement, a continuous and/or discontinuous seal ring 1252 is formed on the outer periphery of the mixed liquid lead-out structure 125, and a profile seal groove 113 adapted to the seal ring 1252 is formed at a corresponding position of the profile fitting groove 111. Sealing ring 1252 is at least partially made of a soft and/or flexible material, which allows sealing ring 1252 to be squeezed into contoured sealing groove 113 after being squeezed, which on the one hand improves the tightness of fit between cover 11 and the mixed liquid outlet structure, and on the other hand enables further sealing of catheter tube 1251 and liquid outlet 1222.

In a preferred embodiment, the mixing tube 122 is at least partially made of a soft and/or pliable material, which allows the volume of the mixing chamber 1221 to be reduced accordingly after the mixing tube 122 is squeezed. After uniform mixing, the cover 11 is removed to expose the liquid outlet 1222, and the mixed solution in the liquid mixing chamber 1221 can be extruded out by pressing the liquid mixing tube 122 as required.

To facilitate the docking of the inner tube 123 with the docking tube 13, the distal end 1231 of the inner tube 123 is exposed from the guide lumen 1211.

Example 3

Fig. 4 shows embodiment 3 of the present invention, which differs from embodiments 1 and 2 in that: at least one ventilation groove 136 is formed in the outer surface of the sidewall 134 of the butt joint pipe 13, and the ventilation groove 136 extends axially from the butt joint port 132 along the outer surface of the sidewall 134 of the butt joint pipe 13.

Further, the outer surface of the sidewall 134 of the butt joint pipe 13 is formed with a ring of circumferentially arranged sealing slopes 135, and the outer diameter of the sealing slopes 135 gradually increases in a direction away from the butt joint port 132 such that the outer surface of the sealing slopes 135 forms an included angle α with the axis of the butt joint pipe 13. The sealing ramp 135 is able to seal the opening of the guide tube 121 when the inner tube 123 is progressively inserted into the docking cavity 131 and eventually causes the guide tube 121 to mate to the sealing ramp 135.

In an exemplary embodiment, the included angle α has a magnitude of 3 ° to 10 °; the sealing ramp 135 is at least partially made of a soft and/or pliable material, which allows the sealing ramp 135 to further seal the opening of the guide tube 121 when the guide tube 121 is mated to the sealing ramp 135.

As a further improvement, the venting groove 136 extends axially from the docking port 132 along the outer surface of the sidewall 134 of the docking tube 13 and terminates at the sealing ramp 135.

As a further improvement, the outer surface of the side wall 134 of the butt joint pipe 13 is formed with a ring of circumferentially arranged sealing rings 133, and the maximum outer diameter of the sealing slope 135 is terminated on the end face of the sealing rings 133.

Example 4

Embodiment 4 discloses a method for quantitative sampling and filling using the quantitative sampling and filling device 1, including the steps of:

step S1, referring to fig. 1 to 3, provides a quantitative sampling and filling device, including: the outer tube 12 comprises a guide tube 121 defining a guide cavity 1211 and a liquid mixing tube 122 defining a liquid mixing cavity 1221, the guide cavity 1211 is communicated with the liquid mixing cavity 1221, and a liquid outlet 1222 communicated with the liquid mixing cavity 1221 is formed in the liquid mixing tube 122;

an inner tube 123 having a proximal end 126 and a distal end 1231, at least a portion of the inner tube 123 being mounted in the guiding cavity 1211, the proximal end 126 of the inner tube 123 sealing off an end of the guiding cavity 1211 to block off the guiding cavity 1211 from the liquid mixing cavity 1221; and

a capillary tube 124 extending longitudinally inside the inner tube 123 from the distal end 1231 to the proximal end 126, and the liquid mixing chamber 1221 communicating with the outside through the capillary tube 124;

step S2, providing a cover 11, wherein the cover 11 seals the liquid outlet 1222, and the inner tube 123 is inserted into the sample cup, so that the sample liquid in the sample cup is sucked by the capillary tube 124 and temporarily stored in the liquid mixing chamber 1221;

step S3, inserting the inner tube 123 into the buffer cup 14 to flush the buffer solution into the mixing chamber 1221 along the capillary tube 124, wherein the buffer solution is mixed with the sample during the flushing process;

step S4, after mixing uniformly, the cover 11 is removed to expose the liquid outlet 1222, and the mixed solution in the liquid mixing cavity 1221 can be extruded out as required by squeezing the liquid mixing tube 122 to achieve quantitative filling.

Further, in step S3, the mixing tube 122 is shaken by a human hand and/or a shaking device to mix the buffer solution with the sample more uniformly.

Further, the mixing tube 122 is at least partially made of a soft and/or pliable material, so that the volume of the mixing chamber 1221 can be reduced after the mixing tube 122 is squeezed.

Further, in step S4, after the filling is completed, the cover 11 is coupled to the liquid mixing tube 122 to close the liquid outlet 1222 again.

Further, between the step S2 and the step S3, a step S21 is further provided:

providing a docking pipe 13 defining a docking cavity 131, wherein one end of the docking pipe 13 is open to form a docking port 132 communicated with the docking cavity 131, and the buffer cup 14 enters and exits the docking cavity 131 through the docking port 132;

here, in step S3, the distal end 1231 of the inner tube 123 is gradually inserted into the docking cavity 131 through the docking port 132, and is finally inserted into the buffer cup 14 under the guidance of the sidewall of the docking tube 13.

Further, the inner tube 123 is spaced apart from the sidewall of the guide tube 121 to define an avoidance space between the inner tube 123 and the guide tube 121;

in step S3, when the inner tube 123 is inserted into the docking cavity 131, the sidewall 134 of the docking tube 13 is received by the escape space.

Further, the proximal end 126 of the inner tube 123 is a partition assembly, which comprises:

at least two partition units 1261 arranged coaxially and at intervals; and

at least one connecting unit 1263, each connecting unit 1263 axially connecting two adjacent partition units 1261;

wherein, the partition unit 1261 is provided with a vent 1262; the vent holes 1262 of any one of the partition units 1261 are axially staggered from the vent holes 1262 of the other partition units 1261 adjacent to the partition unit 1261;

in step S3, when the inner tube 123 is inserted into the docking chamber 131, the vent 1262 ensures that the air pressure of the liquid mixing chamber 1221 is consistent with that of the guiding chamber 1211 so that the buffer solution can be flushed into the liquid mixing chamber 1221, and the partition 1261 can block the liquid splashed from the liquid mixing chamber 1221 during the imbibing process from the guiding chamber 1211.

As a further improvement, the outer surface of the sidewall 134 of the butt-joint pipe 13 is provided with at least one ventilation groove 136, and the ventilation groove 136 extends from the butt-joint port 132 along the outer surface of the sidewall 134 of the butt-joint pipe 13 in the axial direction;

in step S3, when the inner tube 123 is gradually inserted into the docking cavity 131, the sidewall 134 of the docking tube 13 is gradually received by the avoiding space, and the guiding cavity 1211 can be kept in communication with the outside atmosphere through the air-permeable groove 136, so as to prevent the sidewall 134 of the docking tube 13 from further extending due to the gradually increased air pressure in the guiding cavity 1211 during the process of gradually entering the avoiding space.

As a further improvement, the outer surface of the side wall 134 of the butt joint pipe 13 is formed with a ring of circumferentially arranged sealing slopes 135, the outer diameter of the sealing slopes 135 gradually increases in a direction away from the butt joint port 132 so that the outer surface of the sealing slopes 135 forms an included angle α with the axis of the butt joint pipe 13;

wherein, in step S3, when the inner tube 123 is gradually inserted into the docking cavity 131 and finally the guide tube 121 is fitted to the sealing slope 135, the sealing slope 135 can seal the opening of the guide tube 121.

As a further improvement, the distal end 1231 of the inner tube 123 is tapered such that it facilitates piercing the closing membrane of the buffer cup 14 and into the buffer chamber 141; the bottom of the buffer liquid cavity 141 is a profiling structure adapted to the distal end 1231 of the inner tube 123;

in step S3, when the distal end 1231 of the inner tube 123 is inserted into the buffer cup 14 and finally reaches the bottom of the buffer chamber 141, the outer surface of the distal end 1231 is attached to the bottom of the buffer chamber 141, so that there is no space to accommodate the buffer, and the buffer is finally squeezed into the capillary tube 124.

As a further improvement, a circle of liquid scraping rings 1232 are formed at the junction of the distal end 1231 of the inner tube 123 and the main body of the inner tube 123, and the outer diameter of the liquid scraping rings 1232 is larger than the inner diameter of the buffer liquid cavity 141;

the liquid scraping ring 1232 is at least partially made of a soft and/or flexible material, so that in step S3, as the distal end 1231 of the inner tube 123 is gradually inserted into the buffer chamber 141, the liquid scraping ring 1232 can be pressed to tightly abut against the sidewall of the buffer chamber 141 to scrape and push the buffer solution adhered to the sidewall of the buffer chamber 141 to the bottom of the buffer chamber 141.

As a further improvement, after step S4, the method further includes step S5:

after the quantitative filling is completed, the cover 11 is used to close the liquid outlet 1222 again to prevent the liquid in the liquid mixing cavity 1221 from dripping out or prevent the inside of the liquid mixing cavity 1221 from being polluted by the outside.

The number of apparatuses and the scale of the process described herein are intended to simplify the description of the present invention. Applications, modifications and variations of the present invention will be apparent to those skilled in the art.

The features of the different implementations described herein may be combined to form other embodiments not specifically set forth above. The components may be omitted from the structures described herein without adversely affecting their operation. Further, various individual components may be combined into one or more individual components to perform the functions described herein.

Furthermore, while embodiments of the invention have been described above, it is not limited to the applications set forth in the description and the embodiments, which are fully applicable in a variety of fields of endeavor to which the invention pertains, and further modifications may readily be made by those skilled in the art, it being understood that the invention is not limited to the details shown and described herein without departing from the general concept defined by the appended claims and their equivalents.