阅读说明：本技术 一种含抗阿尔兹海默症因子刺五加制剂配方及制备方法 (Formula and preparation method of acanthopanax preparation containing anti-Alzheimer's disease factor ) 是由 王振宇 包美丽 于 2021-08-16 设计创作，主要内容包括：本发明公布了一种含抗阿尔兹海默症因子的刺五加制剂配方及制作方法,由以下原料制备而成：刺五加5—50克,白果3—15克,金枪鱼油0.5—2毫升,鲑鱼油0.5—2毫升,红松松籽油0.5—2毫升,脑磷脂1——5毫升,葡萄糖酯5—15克。制剂适合于中老年人食用。(The invention discloses a formula of an acanthopanax root preparation containing an anti-Alzheimer's disease factor and a preparation method thereof, wherein the acanthopanax root preparation is prepared from the following raw materials: 5 to 50 g of acanthopanax, 3 to 15 g of ginkgo, 0.5 to 2 ml of tuna oil, 0.5 to 2 ml of salmon oil, 0.5 to 2 ml of Korean pine seed oil, 1 to 5 ml of cephalin and 5 to 15 g of glucose ester. The preparation is suitable for middle aged and elderly people.)

1. An acanthopanax root preparation containing factors resisting Alzheimer's disease is characterized by being prepared from the following raw materials, wherein the raw materials comprise acanthopanax root, ginkgo seed, tuna oil, salmon oil and Korean pine seed oil, and the dosage of the raw materials is as follows: 5 to 50 g of acanthopanax, 3 to 15 g of ginkgo, 0.5 to 2 ml of tuna oil, 0.5 to 2 ml of salmon oil, 0.5 to 2 ml of pinus koraiensis oil, 1 to 5 ml of cephalin and 5 to 15 g of glucose ester.

2. The acanthopanax root preparation containing the anti-Alzheimer's disease factor according to claim 1, which is characterized by comprising the following raw materials in percentage by weight: the preparation raw materials are as follows: acanthopanax root 5.0-30.0 g, ginkgo 3.0-10.0 g, tuna oil 0.5-1.0 ml, salmon oil 0.5-1.0 ml, red pine oil 0.5-1.0 ml, cephalin 1.0-2 ml and glucose ester 5-5 g.

3. The acanthopanax root preparation containing the anti-Alzheimer's disease factor according to claim 1, which is characterized by comprising the following raw materials in percentage by weight: 25-50 g of acanthopanax, 10-15 g of ginkgo, 1.0-2.0 ml of tuna oil, 1.0-2.0 ml of salmon oil, 1.0-2.0 ml of pinus koraiensis oil, 3.0-5.0 ml of cephalin and 10-15 g of glucose ester.

4. The method for preparing acanthopanax senticosus preparation containing anti-alzheimer's disease factor according to claims 1-3, characterized by comprising the following steps:

firstly, extracting acanthopanax senticosus by using 40-55% of ethanol to obtain extract liquor, concentrating to obtain paste extract, vacuum freeze-drying to obtain acanthopanax senticosus extract freeze-dried powder, secondly, extracting ginkgo with 40-55% of ethanol to obtain extract liquor, concentrating to obtain paste, vacuum freeze-drying to obtain ginkgo extract freeze-dried powder, thirdly, mixing tuna oil, cephalin and glucose ester, uniformly stirring to obtain paste, vacuum freeze-drying to obtain tuna oil composite freeze-dried powder, fourthly, mixing salmon oil, cephalin and glucose ester, uniformly stirring to obtain paste, vacuum freeze-drying to obtain salmon oil composite freeze-dried powder, fifthly, mixing pinus koraiensis seed oil, cephalin and glucose ester, uniformly stirring to obtain paste, vacuum freeze-drying to obtain pinus koraiensis seed oil composite freeze-dried powder, sixthly, mixing the acanthopanax, ginkgo extract freeze-dried powder obtained in the previous step, fish oil and pine seed oil composite freeze-dried powder, subpackaging, and sterilizing by radiation to obtain radix Acanthopanacis Senticosi preparation containing anti-Alzheimer's disease factor.

Technical Field

The invention relates to a formula of an acanthopanax root preparation containing an anti-Alzheimer disease factor and a preparation method thereof, which can be used in the field of middle-aged and elderly people food.

Background

With the development of science and technology in China, China already enters the elderly society, the elderly population is more and more, and patients with Alzheimer's disease are increased. The main symptoms are: memory decline, cognitive dysfunction, language dysfunction, disorientation, emotional instability, loss of motivation, inability to self-care, etc. Acanthopanax senticosus has the functions of invigorating spleen and tonifying kidney, and is used for treating restlessness, insomnia, dreaminess, amnesia and other symptoms caused by deficiency of both heart and spleen and deficiency of spleen and kidney. The ginkgo biloba has the effects of strengthening brain and benefiting intelligence, contains dopamine components which are substances for increasing neurotransmission, thereby enhancing the capability of an organism for transmitting information, effectively improving the memory and effectively preventing and treating the Alzheimer disease. The oily fish contains a large amount of Omega-3, which not only has good prevention effect on cardiovascular and cerebrovascular diseases, but also has certain inhibition capability on Alzheimer's disease. Pinolenic acid and phospholipid in the pine seed oil of Korean pine can promote the formation of nerve by brain, and enhance memory, reaction and cognitive ability. The acanthopanax root is taken as a main raw material to be compounded with food raw materials of ginkgo, tuna oil, salmon oil, pinus koraiensis seed oil and the like with anti-Alzheimer's disease factors, so that the acanthopanax root food is prepared into a novel preparation suitable for old people to eat.

Disclosure of Invention

The invention aims to provide an acanthopanax root preparation containing an anti-Alzheimer disease factor, which is prepared into a novel preparation suitable for old people to eat.

The purpose of the invention is realized by the following technical scheme:

an Acanthopanax senticosus preparation containing factor for resisting Alzheimer disease is prepared from radix Acanthopanacis Senticosi, semen Ginkgo, tuna oil, salmon oil, and Korean pine seed oil. The required dosage of each raw material is as follows: acanthopanax root 5.0-50.0 g, ginkgo 3.0-15.0 g, tuna oil 0.5-2.0 ml, salmon oil 0.5-2.0 ml, red pine oil 0.5-2.0 ml, cephalin 1.0-5.0 ml and glucose ester 5.0-15.0 g.

A method for preparing radix Acanthopanacis Senticosi preparation containing anti-Alzheimer's disease factor comprises the following steps:

firstly, extracting acanthopanax senticosus with 40-95% ethanol to obtain an extract, concentrating to obtain a paste extract, and carrying out vacuum freeze-drying to obtain the acanthopanax senticosus extract freeze-dried powder.

Secondly, extracting the ginkgo with 40-95% ethanol to obtain extract liquor, concentrating to obtain paste, and carrying out vacuum freeze-drying to obtain the ginkgo extract freeze-dried powder.

And thirdly, mixing the tuna oil, the cephalin and the glucose ester, uniformly stirring to form a paste, and carrying out vacuum freeze-drying to obtain the tuna oil composite freeze-dried powder.

Fourthly, mixing the salmon oil, the cephalin and the glucose ester, stirring the mixture evenly to form a paste, and carrying out vacuum freeze-drying to obtain the salmon oil composite freeze-dried powder.

And fifthly, mixing the pine nut oil of the Korean pine with cephalin and glucose ester, stirring uniformly to form paste, and carrying out vacuum freeze-drying to obtain the composite freeze-dried powder of the pine nut oil of the Korean pine.

Sixthly, mixing the acanthopanax and ginkgo extract freeze-dried powder obtained in the step with fish oil and pine seed oil compound freeze-dried powder, subpackaging, and performing radiation sterilization to obtain the acanthopanax preparation containing the anti-Alzheimer's disease factors.

In the formula, acanthopanax has the functions of tonifying spleen and kidney, and is used for treating symptoms such as restlessness, insomnia, dreaminess, amnesia and the like caused by deficiency of both heart and spleen and deficiency of spleen and kidney. The ginkgo biloba has the effects of strengthening brain and benefiting intelligence, contains dopamine components which are substances for increasing neurotransmission, thereby enhancing the capability of an organism for transmitting information, effectively improving the memory and effectively preventing and treating the Alzheimer disease. The oily fish contains a large amount of Omega-3, which not only has good prevention effect on cardiovascular and cerebrovascular diseases, but also has certain inhibition capability on Alzheimer's disease. Pinolenic acid and phospholipid in the pine seed oil of Korean pine can promote the formation of nerve by brain, and enhance memory, reaction and cognitive ability. The raw materials are processed to obtain acanthopanax, ginkgo extract, fish oil and pine seed oil glucose ester compound freeze-dried powder, and the acanthopanax preparation containing the factors for resisting Alzheimer disease is prepared by stirring and mixing.

Detailed Description

The technical solution of the present invention is further described below, but not limited thereto, and modifications or equivalent substitutions may be made to the technical solution of the present invention without departing from the spirit and scope of the technical solution of the present invention, and are intended to be covered by the scope of the present invention.

Example 1:

an Acanthopanax senticosus preparation containing factor for resisting Alzheimer disease is prepared from radix Acanthopanacis Senticosi, semen Ginkgo, tuna oil, salmon oil, and Korean pine seed oil. The required dosage of each raw material is as follows: acanthopanax root 5.0-30.0 g, ginkgo 3.0-10.0 g, tuna oil 0.5-1.0 ml, salmon oil 0.5-1.0 ml, red pine oil 0.5-1.0 ml, cephalin 1.0-2 ml and glucose ester 5-10 g.

A method for preparing radix Acanthopanacis Senticosi preparation containing anti-Alzheimer's disease factor comprises the following steps:

firstly, extracting acanthopanax senticosus with 40-55% ethanol to obtain an extract, concentrating to obtain a paste extract, and carrying out vacuum freeze-drying to obtain the acanthopanax senticosus extract freeze-dried powder.

Secondly, extracting the ginkgo with 40-55% of ethanol to obtain extract liquor, concentrating to obtain paste, and carrying out vacuum freeze-drying to obtain the ginkgo extract freeze-dried powder.

And thirdly, mixing the tuna oil, the cephalin and the glucose ester, uniformly stirring to form a paste, and carrying out vacuum freeze-drying to obtain the tuna oil composite freeze-dried powder.

Fourthly, mixing the salmon oil, the cephalin and the glucose ester, stirring the mixture evenly to form a paste, and carrying out vacuum freeze-drying to obtain the salmon oil composite freeze-dried powder.

And fifthly, mixing the pine nut oil of the Korean pine with cephalin and glucose ester, stirring uniformly to form paste, and carrying out vacuum freeze-drying to obtain the composite freeze-dried powder of the pine nut oil of the Korean pine.

Sixthly, mixing the acanthopanax and ginkgo extract freeze-dried powder obtained in the step with fish oil and pine seed oil compound freeze-dried powder, subpackaging, and performing radiation sterilization to obtain the acanthopanax preparation containing the anti-Alzheimer's disease factors.

Example 2

The difference between the embodiment and the embodiment 1 is that the required dosage of each raw material is as follows: 25-50 g of acanthopanax, 10-15 g of ginkgo, 1.0-2.0 ml of tuna oil, 1.0-2.0 ml of salmon oil, 1.0-2.0 ml of pinus koraiensis oil, 3.0-5.0 ml of cephalin and 10-15 g of glucose ester.