阅读说明：本技术 一种清润菊多糖提取装置及其提取工艺 (Extraction device and extraction process for polysaccharide of Qingrun chrysanthemum ) 是由 邱小明 童冰 于 2021-07-22 设计创作，主要内容包括：本发明提供了一种清润菊多糖提取装置,包括水提装置、酸碱提取装置以及连通水提装置和酸碱提取装置的输送装置；输送装置将水提装置提取后的水提液和滤渣输送至酸碱提取装置。本发明的有益效果：采用水提装置和酸碱提取装置同时对清润菊多糖进行提取,提高了原料利用率和多糖的提取率。(The invention provides a Qingrun chrysanthemum polysaccharide extraction device, which comprises a water extraction device, an acid-base extraction device and a conveying device communicated with the water extraction device and the acid-base extraction device; and the conveying device conveys the water extract and the filter residue extracted by the water extraction device to the acid-base extraction device. The invention has the beneficial effects that: the water extraction device and the acid-base extraction device are adopted to simultaneously extract the polysaccharide of the Qingrun chrysanthemum, so that the utilization rate of raw materials and the extraction rate of the polysaccharide are improved.)

1. The utility model provides a qingrun chrysanthemum polysaccharide extraction element which characterized in that: comprises a water extraction device, an acid-base extraction device and a conveying device communicated with the water extraction device and the acid-base extraction device; the conveying device conveys the water extract and the filter residue extracted by the water extraction device to the acid-base extraction device;

the water extraction device comprises a first shell, a feed hole positioned at the upper end of the first shell and a first liquid outlet positioned at the lower end of the first shell; a first stirring chamber, a heat extraction chamber and a first filtering part are sequentially arranged in the first shell from top to bottom; a combined stirrer is arranged in the first stirring chamber, and a simple stirring rod is arranged in the heat extraction chamber;

the acid-base extraction device also comprises a second shell, a filter residue input port is arranged at the upper end of the second shell, and an acid-base extraction chamber, a dialysis chamber and a concentration chamber are sequentially arranged in the second shell from top to bottom; the concentration chamber is provided with a liquid inlet opening communicated with the first liquid outlet.

2. The apparatus of claim 1, wherein: the water extraction device also comprises a first isolation mechanism, wherein the first isolation mechanism comprises a first isolation layer for isolating the first stirring chamber and the heat extraction chamber and a second isolation layer for isolating the heat extraction chamber and the first filtering part; the first isolation layer comprises a first opening, a first isolation cylinder and a first isolation plate used for opening and closing the first opening, the first isolation plate is connected with a piston rod of the first isolation cylinder, the second isolation layer comprises a second opening, a second isolation cylinder and a second isolation plate used for opening and closing the first opening, and the second isolation plate is connected with a piston rod of the second isolation cylinder.

3. The apparatus of claim 2, wherein: first filter house one end top is equipped with first sediment mechanism that pushes away, and the top of the other end is formed with the slag notch, first sediment mechanism that pushes away includes first sediment cylinder and the first push pedal of pushing away, and first push pedal is connected with the first piston rod that pushes away the sediment cylinder.

4. The apparatus of claim 3, wherein: the first filter part comprises a first filter layer and a second filter layer; the mesh number of the second filter layer is larger than that of the first filter layer.

5. The apparatus of claim 3, wherein: the acid-base extraction chamber comprises a base extraction reaction chamber and an acid reaction chamber positioned below the base extraction reaction chamber;

the acid-base extraction device also comprises a second filtering part for filtering residues and a second isolation mechanism; the second isolation mechanism comprises a third isolation layer for isolating the alkali extraction reaction chamber and the acid reaction chamber, a fourth isolation layer for isolating the acid reaction chamber and the dialysis chamber, and a fifth isolation layer for isolating the dialysis chamber and the concentration chamber; the third isolation layer comprises a third opening, a third isolation cylinder and a third isolation plate for opening and closing the third opening, the third isolation plate is connected with a piston rod of the third isolation cylinder, the fourth isolation layer comprises a fourth opening, a fourth isolation cylinder and a fourth isolation plate for opening and closing the fourth opening, the fourth isolation plate is connected with a piston rod of the fourth isolation cylinder, the fifth isolation layer comprises a fifth opening, a fifth isolation cylinder and a fifth isolation plate for opening and closing the fifth opening, and the fifth isolation plate is connected with a piston rod of the fifth isolation cylinder;

the second filter part is located between the third isolation layer and the fourth isolation layer, and one end top of the second filter part is provided with a second slag pushing mechanism, the second slag pushing mechanism comprises a second slag pushing cylinder and a second push plate, and the second push plate is connected with a piston rod of the second slag pushing cylinder.

6. The apparatus of claim 5, wherein: the dialysis chamber comprises a first dialysis chamber, a second dialysis chamber and a dialysis layer for isolating the first dialysis chamber from the second dialysis chamber.

7. The apparatus of claim 6, wherein: the dialysis layer adopts cellulose dialysis membrane or cellophane.

8. The apparatus of claim 1, wherein: the horizontal height of the first liquid outlet is not lower than that of the liquid inlet opening.

9. The apparatus of claim 1, wherein: the conveying device comprises a conveying pipe, a conveying belt and a connecting frame; the one end and the first liquid outlet intercommunication of conveyer pipe, the other end and feed liquor trompil intercommunication, the inside end of conveyer belt rotates respectively and is connected with the action wheel and follows the driving wheel, pass through the conveyer belt from the driving wheel and be connected with the action wheel transmission, the link is located conveyer belt one side outer end, link terminal surface inside rotation is connected with a plurality of rollers.

10. An extraction process based on the chrysanthemum polysaccharide extraction device of any one of claims 1 to 9, which is characterized in that: the extraction process comprises the following steps:

(1) degreasing the chrysanthemum morifolium ramat after removing impurities for 3-4 times each time for 3-4 days by adding the chrysanthemum morifolium ramat after removing impurities into methanol with the weight of 20-35 times of the chrysanthemum morifolium ramat; putting the degreased clear and moist chrysanthemum into a first stirring chamber of a water extraction device, adding clear water, stirring at a high speed and smashing to obtain a mixed solution, and feeding the mixed solution into a thermal extraction chamber;

(2) adding hot water into the heat extraction chamber, mixing with the mixed solution, stirring for the second time, extracting with hot water, and filtering the mixed solution with the first filter unit to obtain filtrate as water extractive solution;

(3) the water extract flows into a concentration chamber of the acid-base extraction device from the first liquid outlet; the first residue pushing mechanism pushes the filter residue out of the first filtering part; conveying the filter residue to an alkali extraction reaction chamber of an acid-alkali extraction device by using a conveying device;

(4) adding an alkaline solution into the alkaline extraction reaction chamber, and stirring again to obtain an alkaline extract;

(5) the alkali extract enters an acid reaction chamber after being filtered by a second filtering part, an acid solution is added, the pH value is adjusted to about 7, and then the alkali extract enters a first dialysis chamber for dialysis treatment, and water can be filled in a second dialysis chamber and is replaced for multiple times;

(6) mixing the dialyzed alkali extract with the water extract in a concentration chamber, heating the mixing chamber to obtain a concentrated solution, and taking out the concentrated solution;

(7) adding methanol into the concentrated solution for secondary removal of fat-soluble impurities, removing proteins by using a Sevage reagent, and standing overnight at 0-4 ℃;

(8) centrifuging the concentrated solution obtained in the step (7), and removing supernatant;

(9) and (4) rinsing the chrysanthemum polysaccharide obtained in the step (8) with absolute ethyl alcohol and acetone for 2-4 times, and drying and precipitating to obtain the chrysanthemum polysaccharide.

[ technical field ] A method for producing a semiconductor device

The invention relates to the field of polysaccharide extraction, and in particular relates to a Qingrun chrysanthemum polysaccharide extraction device and an extraction process thereof.

[ background of the invention ]

The polysaccharide of the chrysanthemum morifolium ramat is one of effective medicinal active ingredients in the chrysanthemum morifolium ramat. The chrysanthemum morifolium ramat is a common traditional Chinese medicine, basically has no toxic or side effect on a human body, is widely applied to developing health-care beverages, and a plurality of polysaccharide extraction devices appear in the market in order to facilitate the extraction of polysaccharide, but the polysaccharide extraction device in the prior art has complicated extraction mode, low extraction rate and poor purity, and the quality of the polysaccharide is influenced; meanwhile, the polysaccharide is extracted in various ways, including water extraction, acid-base extraction and the like, but the polysaccharide extracted by the alkali extraction is easy to hydrolyze under strong alkalinity. In view of the problems of the polysaccharide extraction device and method, the inventors of the present invention have conducted extensive studies to solve the problems.

[ summary of the invention ]

The invention aims to solve the technical problem of providing a Qingrun chrysanthemum polysaccharide extraction device and an extraction process thereof, wherein the Qingrun chrysanthemum polysaccharide extraction device has the advantages of convenient extraction mode, high utilization rate and extraction rate and better quality.

The invention is realized by the following steps: a polysaccharide extraction device for clear-moistening chrysanthemum comprises a water extraction device, an acid-base extraction device and a conveying device communicated with the water extraction device and the acid-base extraction device; the conveying device conveys the water extract and the filter residue extracted by the water extraction device to the acid-base extraction device;

the water extraction device comprises a first shell, a feed hole positioned at the upper end of the first shell and a first liquid outlet positioned at the lower end of the first shell; a first stirring chamber, a heat extraction chamber and a first filtering part are sequentially arranged in the first shell from top to bottom; a combined stirrer is arranged in the first stirring chamber, and a simple stirring rod is arranged in the heat extraction chamber;

the acid-base extraction device also comprises a second shell, a filter residue input port is arranged at the upper end of the second shell, and an acid-base extraction chamber, a dialysis chamber and a concentration chamber are sequentially arranged in the second shell from top to bottom; the concentration chamber is provided with a liquid inlet opening communicated with the first liquid outlet.

Further, the water extraction device also comprises a first isolation mechanism, wherein the first isolation mechanism comprises a first isolation layer for isolating the first stirring chamber and the heat extraction chamber and a second isolation layer for isolating the heat extraction chamber and the first filtering part; the first isolation layer comprises a first opening, a first isolation cylinder and a first isolation plate used for opening and closing the first opening, the first isolation plate is connected with a piston rod of the first isolation cylinder, the second isolation layer comprises a second opening, a second isolation cylinder and a second isolation plate used for opening and closing the first opening, and the second isolation plate is connected with a piston rod of the second isolation cylinder.

Furthermore, first filter house one end top is equipped with first sediment mechanism that pushes away, and the top of the other end is formed with the slag notch, first sediment mechanism that pushes away includes first sediment cylinder and first push pedal, and first push pedal is connected with the first piston rod that pushes away the sediment cylinder.

Further, the first filter part comprises a first filter layer and a second filter layer; the mesh number of the second filter layer is larger than that of the first filter layer.

Further, the acid-base extraction chamber comprises a base extraction reaction chamber and an acid reaction chamber positioned below the base extraction reaction chamber; the acid-base extraction device also comprises a second filtering part for filtering residues and a second isolation mechanism; the second isolation mechanism comprises a third isolation layer for isolating the alkali extraction reaction chamber and the acid reaction chamber, a fourth isolation layer for isolating the acid reaction chamber and the dialysis chamber, and a fifth isolation layer for isolating the dialysis chamber and the concentration chamber, the third isolation layer comprises a third opening, a third isolation cylinder and a third isolation plate for opening and closing the third opening, the third isolation plate is connected with a piston rod of the third isolation cylinder, the fourth isolation layer comprises a fourth opening, a fourth isolation cylinder and a fourth isolation plate for opening and closing the fourth opening, the fourth isolation plate is connected with a piston rod of the fourth isolation cylinder, the fifth isolation layer comprises a fifth opening, a fifth isolation cylinder and a fifth isolation plate for opening and closing the fifth opening, and the fifth isolation plate is connected with a piston rod of the fifth isolation cylinder; the second filter part is located between the third isolation layer and the fourth isolation layer, and one end top of the second filter part is provided with a second slag pushing mechanism, the second slag pushing mechanism comprises a second slag pushing cylinder and a second push plate, and the second push plate is connected with a piston rod of the second slag pushing cylinder.

Further, the dialysis chamber comprises a first dialysis chamber, a second dialysis chamber and a dialysis layer for isolating the first dialysis chamber from the second dialysis chamber.

Further, the dialysis layer adopts cellulose dialysis membrane or cellophane.

Further, the level of the liquid port is not lower than that of the liquid inlet opening.

Further, the conveying device comprises a conveying pipe, a conveying belt and a connecting frame; the one end and the first liquid outlet intercommunication of conveyer pipe, the other end and feed liquor trompil intercommunication, the inside end of conveyer belt rotates respectively and is connected with the action wheel and follows the driving wheel, pass through the conveyer belt from the driving wheel and be connected with the action wheel transmission, the link is located conveyer belt one side outer end, link terminal surface inside rotation is connected with a plurality of rollers.

On the other hand, the extraction process based on the above Qingrun chrysanthemum polysaccharide extraction device is characterized in that: the extraction process comprises the following steps:

(1) degreasing the chrysanthemum morifolium ramat after removing impurities for 3-4 times each time for 3-4 days by adding the chrysanthemum morifolium ramat after removing impurities into methanol with the weight of 20-35 times of the chrysanthemum morifolium ramat; putting the degreased clear and moist chrysanthemum into a first stirring chamber of a water extraction device, adding clear water, stirring at a high speed and smashing to obtain a mixed solution, and feeding the mixed solution into a thermal extraction chamber;

(2) adding hot water into the heat extraction chamber, mixing with the mixed solution, stirring for the second time, extracting with hot water, and filtering the mixed solution with the first filter unit to obtain filtrate as water extractive solution;

(3) the water extract flows into a concentration chamber of the acid-base extraction device from the first liquid outlet; the first residue pushing mechanism pushes the filter residue out of the first filtering part; conveying the filter residue to an alkali extraction reaction chamber of an acid-alkali extraction device by using a conveying device;

(4) adding an alkaline solution into the alkaline extraction reaction chamber, and stirring again to obtain an alkaline extract;

(5) the alkali extract enters an acid reaction chamber after being filtered by a second filtering part, an acid solution is added, the pH value is adjusted to about 7, and then the alkali extract enters a first dialysis chamber for dialysis treatment, and water can be filled in a second dialysis chamber and is replaced for multiple times;

(6) mixing the dialyzed alkali extract with the water extract in a concentration chamber, heating the mixing chamber to obtain a concentrated solution, and taking out the concentrated solution;

(7) adding methanol into the concentrated solution for secondary removal of fat-soluble impurities, removing proteins by using a Sevage reagent, and standing overnight at 0-4 ℃;

(8) centrifuging the concentrated solution obtained in the step (7), and removing supernatant;

(9) and (4) rinsing the chrysanthemum polysaccharide obtained in the step (8) with absolute ethyl alcohol and acetone for 2-4 times, and drying and precipitating to obtain the chrysanthemum polysaccharide.

The invention has the advantages that:

1. by arranging the clear and moist chrysanthemum polysaccharide extraction device comprising the water extraction device, the acid-base extraction device and the conveying device, the clear and moist chrysanthemum polysaccharide is extracted by adopting two extraction methods, namely a hot water extraction method and an alkali extraction method, so that the extraction rate of the polysaccharide is improved, the filter residue is extracted for the second time by adopting the alkali extraction method, the utilization rate of the clear and moist chrysanthemum is improved, and the cost is saved; meanwhile, the extraction device for the polysaccharide of the Qingrun chrysanthemum is convenient to operate, does not need more manual operations, and further saves the cost.

2. The concentration chamber provided with the acid-base extraction device is provided with a liquid inlet opening communicated with the first liquid outlet of the water extraction device, so that the extracted water extract can rapidly enter the concentration chamber, the excessive impurities are prevented from being increased by oxidation, and the heating and concentration with the alkali extract are facilitated; the horizontal height of the first liquid outlet is not lower than that of the liquid inlet opening, so that the water extract can completely flow into the concentration chamber, and waste is prevented.

3. Because the polysaccharide is hydrolyzed when the alkalinity is strong, the concentration of the alkali during the alkali extraction needs to be effectively controlled, so that the acid extraction reaction chamber is arranged below the alkali extraction reaction chamber, the PH value of the alkali extract can be effectively controlled, and the alkali extract is prevented from being hydrolyzed; by providing the dialysis chamber, the alkali extract can be neutralized or dialyzed quickly, so that an alkali extract with a good quality can be obtained.

4. The extraction process for extracting the polysaccharide of the chrysanthemum morifolium ramat has high extraction efficiency and extraction rate

[ description of the drawings ]

The invention will be further described with reference to the following examples with reference to the accompanying drawings.

FIG. 1 is a schematic structural diagram of a polysaccharide extraction device of the Qingrun chrysanthemum.

Fig. 2 is a schematic view of the water extraction apparatus of the present invention.

Fig. 3 is a schematic structural view of an acid-base extraction device according to the present invention.

FIG. 4 is a partial cross-sectional view of the combination mixer of the present invention.

FIG. 5 is a schematic view showing the structure of the conveyor belt and the link frame according to the present invention.

100-a polysaccharide extraction device of Qingrun chrysanthemum,

1-a water extraction device, 11-a first shell, 12-a feed hole, 121-a raw material inlet, 122-a clean water port, 13-a first liquid outlet, 14-a first stirring chamber, 15-a heat extraction chamber, 151-a simple stirring rod, 152-a hot water port, 16-a first filtering part, 161-a first slag pushing mechanism, 1611-a first slag pushing cylinder, 1612-a first pushing plate, 162-a slag outlet, 163-a first filtering layer, 164-a second filtering layer, 17-a combined stirrer, 171-a first stirring shaft, 1711-a first driving shaft, 172-a second stirring shaft, 1721-a second driving shaft, 173-a horizontal rotating blade, 174-a conical helical blade, 175-a first stirring motor, 176-a second stirring motor and 177-a limiting block, 18-first isolation mechanism, 181-first isolation layer, 1811-first isolation cylinder, 1812-first isolation plate, 1813-first opening, 182-second isolation layer, 1821-second isolation cylinder, 1822-second isolation plate, 1823-second opening, 19-drive motor,

2-acid-base extraction device, 21-second shell, 22-filter residue input port, 23-acid-base extraction chamber, 231-alkali extraction reaction chamber, 232-acid reaction chamber, 24-dialysis chamber, 241-first dialysis chamber, 242-second dialysis chamber, 243-dialysis layer, 25-concentration chamber, 26-liquid inlet opening, 27-second filter part, 271-second residue pushing mechanism, 2711-second residue pushing cylinder, 2712-second pushing plate, 28-second isolation mechanism, 281-third isolation layer, 282-fourth isolation layer, 283-fifth isolation layer, 2811-third isolation cylinder, 2812-third isolation plate, 2813-third opening, 2821-fourth isolation cylinder, 2822-fourth isolation plate, 2823-fourth opening, 2831-fifth isolation cylinder, 2832-fifth separating plate, 2833-fifth opening, 29-second liquid outlet,

3-conveying device, 31-conveying belt, 311-driving wheel, 312-driven wheel, 32-connecting frame, 321-roller, 322-side plate and 33-conveying pipe.

[ detailed description ] embodiments

In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings of the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention. Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

Example one

As shown in fig. 1 to 5, the extraction device 100 for chamomile polysaccharide comprises a water extraction device 1, an acid-base extraction device 2, and a conveying device 3 for communicating the water extraction device 1 and the acid-base extraction device 2; and the conveying device 3 conveys the water extract and the filter residue extracted by the water extraction device 1 to the acid-base extraction device 2. By arranging the clear and moist chrysanthemum polysaccharide extraction device 100 comprising the water extraction device 1 and the acid-base extraction device 2, the clear and moist chrysanthemum polysaccharide can be extracted by two extraction methods, namely a hot water extraction method and an alkali extraction method, the hot water extraction method is safe and economical to use in production, the clear and moist chrysanthemum polysaccharide is firstly extracted by the hot water extraction method for the first time to obtain a water extract, and then the alkali extraction method is used for carrying out secondary extraction on filter residues, so that the utilization rate of the clear and moist chrysanthemum is improved; meanwhile, compared with the conventional extraction process, the extraction rate of the polysaccharide is improved, and the raw material cost is saved. Meanwhile, the extraction device 100 for the polysaccharide of the Qingrun chrysanthemum is convenient to operate, and compared with the traditional extraction process, a lot of manual operations are omitted, so that the labor cost is further saved.

As shown in fig. 2, the water extraction device 1 comprises a first housing 11, a feed hole 12 at the upper end of the first housing 11, and a first liquid outlet 13 at the lower end of the first housing 11; first casing 11 is inside to be equipped with first teeter chamber 14, heat from top to bottom in proper order and draws room 15 and first filter house 16, be equipped with combination formula agitator 17 in the first teeter chamber 14 to carry out preliminary mixing to the clear moist chrysanthemum raw materials and smash, form mixed liquid. The feeding hole 12 comprises a fresh chrysanthemum raw material inlet 121 positioned at the top end of the first stirring chamber 14 and a fresh water inlet 122 for adding fresh water. The heat extraction chamber 15 is also provided with a hot water port 152 for adding hot water and a driving motor 19 arranged on the outer wall of the heat extraction chamber 15; the simple stirring rod 151 is arranged in the heat extraction chamber 15, so that the mixed liquid and the hot water are uniformly mixed, the heat extraction efficiency is improved, and the driving motor 19 drives the simple stirring rod 151 to rotate.

The working principle of the water extraction device 1 is as follows: the first stirring chamber 14 primarily stirs and breaks the fresh chrysanthemum raw material to obtain a mixed solution, the mixed solution enters the thermal extraction chamber 15 to be subjected to hot water extraction with hot water, and then the mixed solution is filtered by the first filtering part 16 to obtain the required water extraction solution.

As shown in fig. 4, the combination agitator 17 includes a first agitating shaft 171, a second agitating shaft 172 whose upper end is sleeved inside the first agitating shaft 171, a horizontal rotating blade 173 assembled outside the first agitating shaft 171, and a conical helical blade 174 assembled at the lower end of the second agitating shaft 172. The water extracting device 1 further comprises a first stirring motor 175 and a first driving shaft 1711 for driving the first stirring shaft 171 to work, a second stirring motor 176 and a second driving shaft 1721 for driving the second stirring shaft 172 to work; a first gear is arranged at one end of the first driving shaft 1711, a first external tooth is arranged on the outer wall of the upper end of the first stirring shaft 171, and the first stirring motor 175 drives the first stirring shaft 171 to rotate through the first driving shaft 1711; a second gear is arranged at one end of the second driving shaft 1721, a second external tooth is arranged on the outer wall of the upper end of the second stirring shaft 172, the second stirring motor 176 drives the second stirring shaft 172 to rotate through the second driving shaft 1721, and a limiting block 177 used for abutting against the first stirring shaft 171 is further arranged at the position, above the conical helical blade 174, of the second stirring shaft 172. The angle that expands outward of toper helical blade 174 from top to bottom grow gradually, and when toper helical blade 174 was high-speed rotatory, can produce by the swirl of lower up, the raw materials that the curl up is in first teeter chamber 14 bottom to it is more even to make the raw materials stirring.

The combination mixer 17 has two modes of operation. In the first mode, the first stirring motor 175 and the second stirring motor 176 can control the horizontal rotating blade 173 and the conical helical blade 174 to work simultaneously to stir and chop the chrysanthemum morifolium ramat raw material, the conical helical blade 174 continuously rolls up the raw material at the bottom of the first stirring chamber 14 while stirring and chopping the raw material, and the horizontal rotating blade 173 is matched to stir and chop the raw material, so that the raw material can be chopped more, and the stirring efficiency is improved; in the second mode, the stirring motor 175 can also control the horizontal rotation blade 173 to work alone, after the stirring work is finished, the stirring motor 175 controls the horizontal rotation blade 173 to work alone, the horizontal rotation blade 173 rotates at a high speed to generate downward wind, so that the filter residue attached to the inner wall of the first stirring chamber 14 rapidly flows downward and enters the heat extraction chamber 15, and resource waste is avoided.

As shown in fig. 3, the acid-base extraction device 2 further includes a second housing 21, a residue inlet 22 is disposed at the upper end of the second housing 21, and an acid-base extraction chamber 23, a dialysis chamber 24 and a concentration chamber 25 are sequentially disposed in the second housing 21 from top to bottom; the concentrating chamber 25 is provided with a feed opening 26 and a second outlet 29 communicating with the first outlet 13. The alkali extract can be dialyzed rapidly by arranging the dialysis chamber 24, so that the alkali extract with better quality can be obtained, and the purpose of purification can be achieved; the alkali extract is purified by using the dialysis chamber 24, the operation is simple, and the technology is mature. By providing the inlet opening 26 so that the aqueous extract extracted by the aqueous extraction device 1 enters the concentrating chamber 25, the aqueous extract is prevented from being oxidized to increase redundant impurities, and is conveniently heated and concentrated together with the alkali extract. A second liquid outlet 29 is arranged to take out the concentrated liquid.

The working principle of the acid-base extraction device 2 is as follows: and conveying the filter residue to an acid-base extraction chamber 23 by the conveying device 3 for alkaline extraction to obtain an alkali extract, dialyzing the alkali extract in a dialysis chamber 24, and thermally concentrating the dialyzed alkali extract and water extract in a concentration chamber 25 to obtain the Qingrun chrysanthemum polysaccharide concentrate required by the invention.

In the present invention, the water extraction device 1 further comprises a first isolation mechanism, and the first isolation mechanism 18 comprises a first isolation layer 181 for isolating the first stirring chamber 14 from the heat extraction chamber 15 and a second isolation layer 182 for isolating the heat extraction chamber 15 from the first filter part 16. The first isolation layer 181 includes a first opening 1813, a first isolation cylinder 1811 and a first isolation plate 1812 for opening and closing the first opening 1813, the first isolation plate 1811 is connected with a piston rod of the first isolation cylinder 1812, the control piston rod of the first isolation cylinder 1811 extends and contracts to make the first isolation plate 1811 open or close the first opening 1813, and when the first opening 1813 is opened, the mixture flows to the heat extraction chamber 15; the second isolating layer 182 includes a second opening 1823, a second isolating cylinder 1821 and a second isolating plate 1822 for opening and closing the second opening 1823, the second isolating plate 1822 is connected with a piston rod of the second isolating cylinder 1821, the piston rod of the second isolating cylinder 1821 is controlled to extend and retract to open or close the second isolating plate 1822 and the second opening 1823, and when the second opening 1823 is opened, the hot extracted mixture flows to the first filter part 16 and is filtered to form the water extract.

The upper surfaces of the first isolation layer 181 and the second isolation layer 182 are both arc-shaped, so that filter residues are prevented from remaining in the cavity, and the filter residues can flow downwards.

In the present invention, a first slag pushing mechanism 161 is disposed above one end of the first filtering part 16, a slag outlet 162 is formed above the other end of the first filtering part, the first slag pushing mechanism 161 includes a first slag pushing cylinder 1611 and a first push plate 1612, the first push plate is connected to a piston rod of the first slag pushing cylinder 1611 of the first push plate 1612, and the first slag pushing mechanism 161 pushes out the filter residue to the conveying device 3.

In the present invention, in order to perform the secondary filtration of the water extract and improve the filtration effect, the first filter part 16 includes a first filter layer 163 and a second filter layer 164; the mesh number of the second filter layer 164 is larger than that of the first filter layer 163, thereby further improving the filtering effect. Preferably, the mesh number of the first filter layer 163 is 100 mesh, and the mesh number of the second filter layer 164 is 200 mesh or more.

In the present invention, the acid-base extraction chamber 23 comprises an acid extraction reaction chamber 231 and an acid reaction chamber 232 located below the acid extraction reaction chamber 231; the alkali extraction reaction chamber 231 is provided with an alkaline solution feed inlet, and the acid reaction chamber 232 is provided with an acidic solution feed inlet; . The alkali stripping reaction chamber 231 is provided with a combined stirrer 17 therein, and for the specific structure of the combined stirrer 17, reference is made to the structure of the combined stirrer 17 in the first stirring chamber 14, which is not repeated herein. Since the polysaccharide is hydrolyzed when the alkali is strong, the concentration of the alkali must be effectively controlled when the alkali is extracted, and therefore, the PH of the alkali extract can be quickly controlled by disposing the acid reaction chamber 232 below the alkali extraction reaction chamber 231, thereby preventing the alkali extract from being hydrolyzed.

The acid-base extraction device 2 further comprises a second filtering part 27 for filtering residues and a second isolation mechanism 28; the second isolation mechanism 28 includes a third isolation layer 281 for isolating the alkaline reaction chamber 231 from the acid reaction chamber 232, a fourth isolation layer 282 for isolating the acid reaction chamber 232 from the dialysis chamber 24, and a fifth isolation layer 283 for isolating the dialysis chamber 24 from the concentration chamber 25. The third isolation layer 281 comprises a third opening 2813, a third isolation cylinder 2811 and a third isolation plate 2812 for opening and closing the third opening 2813, the third isolation plate 2812 is connected with a piston rod of the third isolation cylinder 2811, the fourth isolation layer 282 comprises a fourth opening 2823, a fourth isolation cylinder 2821 and a fourth isolation plate 2822, the fourth isolation plate 2822 is connected with a piston rod of the fourth isolation cylinder 2821, the fifth isolation layer 283 comprises a fifth opening 2833, a fifth isolation cylinder 2831 and a fifth isolation plate 2832 for opening and closing the fifth opening 2833, and the fifth isolation plate 2832 is connected with a piston rod of the fifth isolation cylinder 2831. The third isolating cylinder 2811 controls the piston rod to extend and retract so that the third isolating plate 2812 opens or closes the third opening 2813, and when the third opening 2813 is opened, the alkali extract enters the acid reaction chamber 232; the fourth isolating cylinder 2821 controls the piston rod to extend and retract so that the fourth isolating plate 2822 opens or closes the fourth opening 2823, and when the fourth opening 2823 is opened, the alkali extract enters the dialysis chamber 24; the fifth isolation cylinder 2831 controls the piston rod to extend and retract so that the fifth isolation plate 283 opens or closes the fifth opening 2833, and when the fifth opening 2833 is opened, the alkali extracting solution enters the concentrating chamber 25.

The second filter part 27 is located between the third isolation layer 281 and the fourth isolation layer 282 to filter the filter residue sufficiently, and the mesh number of the second filter part 27 is more than 200 meshes. Second filter house 27 one end top is equipped with second and pushes away sediment mechanism 271, the second pushes away sediment mechanism 271 includes that the second pushes away sediment cylinder 2711 and second push pedal 2712, and second push pedal 2712 pushes away the piston rod of sediment cylinder 2711 with the second and is connected, and the second pushes away sediment mechanism 271 pushes away the filter residue right, and second push pedal 2712 extrudes the filter residue on the inner wall of acid-base extraction room 23 to extrude the alkali extract on the filter residue out, improved the extraction rate of the chrysanthemum polysaccharide of moistening fresh. The upper surface of the third isolation layer 281 is arc-shaped so as to facilitate the alkali extract to flow into the acid reaction chamber 232; the upper surface of the fourth isolation layer 282 is rounded to facilitate the flow of the alkali extract to the dialysis chamber 24.

In the present invention, the dialysis chamber 24 comprises a first dialysis chamber 241, a second dialysis chamber 242 and a dialysis layer 243 for isolating the first dialysis chamber 241 from the second dialysis chamber 242. The first dialysis chamber 241 is for containing an alkali extract and the second dialysis chamber 242 is for containing water or a buffer solution. The dialysis layer 243 can be used for dialysis to remove excessive salt and other impurities in the alkali extract, so as to achieve the purpose of purifying the alkali extract. In order to improve the dialysis efficiency, the water or buffer in the second dialysis chamber 242 can be replaced several times to reduce the concentration of the solution in the second dialysis chamber 242 and accelerate the dialysis speed. Of course, the dialysis layer 243 can be replaced to avoid the reduction of the dialysis effect of the dialysis layer 243 after multiple dialysis.

In the present invention, the dialysis layer 243 is a cellulose dialysis membrane or cellophane. The cellulose dialysis membrane or the cellophane is adopted, so that the alkali extract is not polluted, and the dialysis effect is good.

In the present invention, the level of the first liquid outlet 13 is not lower than the level of the inlet opening 26 so that the aqueous extract can completely flow into the concentrating chamber 25.

As shown in fig. 1 and 5, in the present invention, the conveying device 3 includes a conveying pipe 33, a conveyor belt 31, and a connecting frame 32; conveyer pipe 33's one end and first liquid outlet 13 intercommunication, the other end and feed liquor trompil 26 intercommunication, conveyer belt 31's inside end rotates respectively and is connected with action wheel 311 and follows driving wheel 312, follow driving wheel 312 and be connected with action wheel 311 transmission through conveyer belt 31, link 32 is located conveyer belt 31 one side outer end, link 32 terminal surface inside rotates and is connected with a plurality of rollers 321. Preferably, the side plates 322 are fixedly installed at both sides of the connecting frame 32, and the side plates 322 can prevent filter residue from falling to the ground from both sides of the connecting frame 32.

Example two

Referring to fig. 1 to 5, in the extraction process based on the extraction device 100 for chamomile polysaccharide, the extraction device of the first embodiment is used, and details are not repeated here. The extraction process comprises the following steps:

(1) degreasing the chrysanthemum morifolium ramat after removing impurities for 3-4 times each time for 3-4 days by adding the chrysanthemum morifolium ramat after removing impurities into methanol with the weight of 20-35 times of the chrysanthemum morifolium ramat; putting the degreased clear and moist chrysanthemum into a first stirring chamber 14 of a water extraction device 1, adding clear water, stirring at a high speed and smashing to obtain a mixed solution, and feeding the mixed solution into a thermal extraction chamber 15; the methanol is methanol with the concentration of 80-90% so as to degrease the Qingrun chrysanthemum raw material.

(2) Hot water is added into the heat extraction chamber 15 to be mixed with the mixed solution, the hot water extraction is carried out for the second time, after a period of time (2.5 hours to 3.5 hours), the mixed solution is filtered by the first filtering part 16, and the obtained filtrate is the water extract.

(3) The water extract flows from the first liquid outlet 13 to the concentration chamber 25 of the acid-base extraction device 2; the first residue pushing mechanism 161 pushes out the residue from the first filtering portion 16; the conveying device 3 conveys the filter residue to the alkali extraction reaction chamber 231 of the acid-base extraction device 2.

(4) Adding an alkaline solution into the alkaline extraction reaction chamber 231, and stirring again to obtain an alkaline extract; the alkaline solution may be any one of sodium hydroxide, potassium hydroxide, sodium borohydride and potassium borohydride of 0.1-0.5 mol/L.

(5) The alkali extract enters the acid reaction chamber 232 after being filtered by the second filtering part 27, the acid solution is added, the pH value is adjusted to about 7, and then the alkali extract enters the first dialysis chamber 241 for dialysis treatment, and the second dialysis chamber 242 can be filled with water and can be changed for a plurality of times; the acidic solution may be 7mol/L hydrochloric acid, and the second dialysis chamber 242 may also contain a buffer solution.

(6) The dialyzed alkali extract enters a concentration chamber 25 to be mixed with the water extract, the mixing chamber is heated to obtain a concentrated solution, and the concentrated solution is taken out. The alkali extract and the aqueous extract can be concentrated to 1/20 of the original volume under the condition of heating temperature of 85 ℃ to obtain concentrated solution.

(7) Adding methanol into the concentrated solution for secondary removal of fat-soluble impurities, removing proteins by using a Sevag reagent, and standing overnight at 0-4 ℃; the Sevage reagent is specifically prepared from chloroform and butanol at a ratio of 4:1, and pentanol can be used instead of butanol. If necessary, adding proteolytic enzyme in advance to degrade the protein to a certain degree, and then treating with Sevage reagent to obtain better effect.

(8) Centrifuging the concentrated solution obtained in the step (7), and removing supernatant; the concentrated solution may be further centrifuged by a centrifuge, which is a prior art and will not be described herein.

(9) And (4) rinsing the chrysanthemum polysaccharide obtained in the step (8) with absolute ethyl alcohol and acetone for 2-4 times, and drying and precipitating to obtain the chrysanthemum polysaccharide. Since polysaccharides are insoluble in ethanol and acetone, they can be precipitated and purified using ethanol and acetone.

The above description is only a preferred embodiment of the present invention, and all equivalent changes and modifications made within the scope of the claims of the present invention should fall within the scope of the claims of the present invention.