阅读说明：本技术 一种小分子肽多种生物营养剂及其制备方法 (Small molecular peptide multiple biological nutrient and preparation method thereof ) 是由 蒋佩华 于 2021-08-11 设计创作，主要内容包括：本发明提供了一种小分子肽多种生物营养剂及其制备方法,属于生物营养剂技术领域,旨在解决现有的小分子肽生物营养剂的组份少,功效单一的问题；发明的一种小分子肽多种生物营养剂,由以下重量份的原料制备而成：小分子肽42-65份、维生素5-9份、乳化剂13-15、辛烯基琥珀酸淀粉钠30-50份、淮山药6-10份、石斛3-15份、百合6-15份、紫苏6-15份；本发明的小分子肽多种生物营养剂,富含多种有益身体的原料,易于人体吸收,综合营养保健功能更强,利于人体健康。(The invention provides a small molecular peptide multiple biological nutrient and a preparation method thereof, belongs to the technical field of biological nutrients, and aims to solve the problems of few components and single effect of the existing small molecular peptide biological nutrient; the invention relates to a micromolecule peptide multiple biological nutrient which is prepared from the following raw materials in parts by weight: 42-65 parts of small molecular peptide, 5-9 parts of vitamin, 13-15 parts of emulsifier, 30-50 parts of octenyl succinic acid starch sodium, 6-10 parts of common yam rhizome, 3-15 parts of dendrobium, 6-15 parts of lily and 6-15 parts of perilla; the small molecular peptide of the invention is a plurality of biological nutritional agents, is rich in a plurality of raw materials beneficial to human body, is easy to be absorbed by human body, has stronger comprehensive nutrition and health care functions, and is beneficial to human health.)

1. The multi-biological nutrient of the small molecular peptide is characterized by being prepared from the following raw materials in parts by weight:

42-65 parts of small molecular peptide, 5-9 parts of vitamin, 13-15 parts of emulsifier, 30-50 parts of octenyl succinic acid starch sodium, 6-10 parts of common yam rhizome, 3-15 parts of dendrobium, 6-15 parts of lily and 6-15 parts of perilla.

2. The small peptide bionutrient of claim 1, wherein the small peptide is an equal ratio mixture of small casein phosphopeptides and collagen peptides having a molecular weight of less than 600 daltons.

3. The small molecule peptide bionutrient of claim 1, wherein the vitamin is an equal ratio mixture of one or more of vitamin a, vitamin PP, vitamin B2, vitamin B4, vitamin C, inositol, vitamin K2.

4. The multi-biological nutrient of small-molecule peptide, according to claim 1, wherein the emulsifier is an equal ratio mixture of one or more of mono-diglycerol fatty acid ester, oleic acid monoglyceride, sodium stearoyl lactylate, and polyglyceryl fatty acid ester.

5. The method of any one of claims 1-4, comprising the steps of:

s1, preparing the dioscorea opposita thunb, the dendrobium nobile, the lily and the perilla frutescens into dioscorea opposita thunb extracts, the dendrobium nobile extracts, the lily extracts and the perilla frutescens extracts by respectively using a high pressure difference extraction method;

s2, putting sodium starch octenyl succinate and small molecular peptides into a reaction container filled with distilled water, heating to 60 ℃, and stirring at the stirring speed of 220 times/min until the sodium starch octenyl succinate and the small molecular peptides are completely dissolved in the water to obtain a solution A;

s3, mixing and stirring the common yam rhizome extract, the dendrobium extract, the lily extract, the perilla extract and the vitamins uniformly at a stirring speed of 85 times/minute to obtain a solution B;

s4, mixing and stirring the solution B and the emulsifier at the stirring speed of 65 times/min until the mixture is uniformly stirred to obtain emulsion;

s5, shearing and emulsifying the emulsion prepared in the step S4 for 10min at the shearing speed of 12000r/min to obtain an emulsified solution;

and S6, mixing and stirring the solution A and the emulsified solution prepared in the S5, and filling after uniform mixing to obtain the finished product of the micromolecule peptide multi-biological nutrient.

Technical Field

The invention relates to the technical field of biological nutrients, in particular to a small molecular peptide multiple biological nutrient and a preparation method thereof.

Background

The micromolecular peptide has simple structure, small molecular weight and unsaturation, so the micromolecular peptide can directly enter cells in an original shape through the permeation of cell membranes without being digested again or consuming energy, is gradually accepted by the masses due to the excellent biological nutrition health-care function, and is widely applied to the fields of medicines, health care, foods and cosmetics; the small molecular peptide nutritional agent on the market at present has the advantages of simple raw material proportion, single effect, insufficient comprehensive nutrition and health care functions and difficult absorption by human bodies.

Disclosure of Invention

Aiming at the technical defects, the invention aims to provide a plurality of biological nutrients of small molecular peptides and a preparation method thereof, which are rich in a plurality of raw materials beneficial to human body, easy to be absorbed by human body, stronger in comprehensive nutrition and health care function and beneficial to human health.

In order to solve the technical problems, the invention adopts the following technical scheme:

the multi-biological nutrient of the small molecular peptide is characterized by being prepared from the following raw materials in parts by weight:

42-65 parts of small molecular peptide, 5-9 parts of vitamin, 13-15 parts of emulsifier, 30-50 parts of octenyl succinic acid starch sodium, 6-10 parts of common yam rhizome, 3-15 parts of dendrobium, 6-15 parts of lily and 6-15 parts of perilla.

Preferably, the small molecule peptide is an equal proportion mixture of small molecule casein phosphopeptide and collagen peptide with molecular weight less than 600 daltons.

Preferably, the vitamin is one or more of vitamin A, vitamin PP, vitamin B2, vitamin B4, vitamin C, inositol and vitamin K2.

Preferably, the emulsifier is one or more of a mixture of mono-diglycerol fatty acid ester, oleic acid monoglyceride, sodium stearoyl lactylate and polyglyceryl fatty acid ester in equal proportion.

A preparation method of multiple biological nutrients of small molecular peptides is characterized by comprising the following steps:

s1, preparing the dioscorea opposita thunb, the dendrobium nobile, the lily and the perilla frutescens into dioscorea opposita thunb extracts, the dendrobium nobile extracts, the lily extracts and the perilla frutescens extracts by respectively using a high pressure difference extraction method;

s2, putting sodium starch octenyl succinate and small molecular peptides into a reaction container filled with distilled water, heating to 60 ℃, and stirring at the stirring speed of 220 times/min until the sodium starch octenyl succinate and the small molecular peptides are completely dissolved in the water to obtain a solution A;

s3, mixing and stirring the common yam rhizome extract, the dendrobium extract, the lily extract, the perilla extract and the vitamins uniformly at a stirring speed of 85 times/minute to obtain a solution B;

s4, mixing and stirring the solution B and the emulsifier at the stirring speed of 65 times/min until the mixture is uniformly stirred to obtain emulsion;

s5, shearing and emulsifying the emulsion prepared in the step S4 for 10min at the shearing speed of 12000r/min to obtain an emulsified solution;

and S6, mixing and stirring the solution A and the emulsified solution prepared in the S5, and filling after uniform mixing to obtain the finished product of the micromolecule peptide multi-biological nutrient.

Pharmacology of the medicine:

rhizoma dioscoreae: sweet in flavor and neutral in nature. Spleen, lung, kidney; tonify spleen and stomach, promote the production of body fluid and nourish lung, tonify kidney and astringe essence. The health-care function mechanism is that the hormone can be converted into male hormone or female hormone according to the needs of the body, and the hormone imbalance caused by aging and diseases is supplemented, so that people can keep vigorous energy, the capability of resisting diseases is enhanced, the repair of damaged tissues is accelerated, and malignant tumors, diabetes, arteriosclerosis, heart diseases, obesity, senile dementia and the like can be prevented and slowed down.

Dendrobe: nourishing yin, promoting fluid production, strengthening body constitution, invigorating spleen and stomach, protecting liver, promoting function of gallbladder, clearing away heat, strengthening tendons and bones, inhibiting tumor, improving eyesight, and prolonging life.

Lily: nourish yin and moisten lung, clear heart and induce tranquilization. Can be used for treating chronic cough due to yin deficiency, blood-stained sputum, vexation, palpitation, insomnia, dreaminess, and absentmindedness. Has effects in nourishing yin, moistening lung, and relieving cough, and can be used for treating cough due to dryness-heat and blood-stained phlegm due to lung yin deficiency, such as BAIHUA ointment. For chronic cough due to lung deficiency, and hemoptysis due to overstrain cough, such as Bai He Gu jin Tang. Has the effects of clearing away heart-fire and tranquilizing mind, and can be used for treating fever with residual heat, dysphoria, palpitation, insomnia and dreaminess. 10-30 g is decocted for oral administration. Unprocessed for clearing heart fire, stir-baked with honey for moistening lung; to nourish yin, clear heat, nourish essence and blood.

Purple perilla: pungent in flavor and warm in nature, it enters spleen and lung meridians. Folium Perillae and caulis Perillae have the effects of dispelling pathogenic wind, regulating qi-flowing and relieving chest stuffiness, but folium Perillae has the effects of relieving exterior syndrome, dispelling cold, promoting qi circulation and regulating stomach; perilla stem is good at regulating qi, relieving chest stuffiness, alleviating pain and preventing abortion.

The invention has the beneficial effects that: the small molecular peptide of the invention is a plurality of biological nutritional agents, is rich in a plurality of raw materials beneficial to human body, is easy to be absorbed by human body, has stronger comprehensive nutrition and health care functions, and is beneficial to human health.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

A small molecular peptide multiple biological nutrient is prepared from the following raw materials in parts by weight:

46g of small molecular peptide, 5g of vitamin, 15g of emulsifier, 41g of starch sodium octenylsuccinate, 7g of common yam rhizome, 5g of dendrobium, 9g of lily and 11g of perilla.

Furthermore, the small molecule peptide is a mixture of small molecule casein phosphopeptide and collagen peptide with the molecular weight less than 600 daltons in equal proportion.

Furthermore, the vitamins are equal ratio mixture of vitamin A, vitamin B4, inositol and vitamin K2.

Furthermore, the emulsifier is an equal ratio mixture of mono-diglycerol fatty acid ester and polyglyceryl fatty acid ester.

A preparation method of a plurality of biological nutrients of small molecular peptides comprises the following steps:

s1, preparing the dioscorea opposita thunb, the dendrobium nobile, the lily and the perilla frutescens into dioscorea opposita thunb extracts, the dendrobium nobile extracts, the lily extracts and the perilla frutescens extracts by respectively using a high pressure difference extraction method;

s2, putting sodium starch octenyl succinate and small molecular peptides into a reaction container filled with distilled water, heating to 60 ℃, and stirring at the stirring speed of 220 times/min until the sodium starch octenyl succinate and the small molecular peptides are completely dissolved in the water to obtain a solution A;

s3, mixing and stirring the common yam rhizome extract, the dendrobium extract, the lily extract, the perilla extract and the vitamins uniformly at a stirring speed of 85 times/minute to obtain a solution B;

s4, mixing and stirring the solution B and the emulsifier at the stirring speed of 65 times/min until the mixture is uniformly stirred to obtain emulsion;

s5, shearing and emulsifying the emulsion prepared in the step S4 for 10min at the shearing speed of 12000r/min to obtain an emulsified solution;

and S6, mixing and stirring the solution A and the emulsified solution prepared in the S5, and filling after uniform mixing to obtain the finished product of the micromolecule peptide multi-biological nutrient.

The high pressure difference extraction method utilizes the high pressure difference to ensure that cells are instantaneously burst and fully contacted with a solvent, thereby realizing the primary condition of the extraction rate of more than 95 percent, solving the problem of consistency of the botanical drugs or the botanical extracts by the multi-stage membrane separation technology, and recombining according to the standard proportion to ensure the consistency of each batch of products; alternatively, membrane separation techniques may physically remove unwanted components. The multi-stage membrane concentration technology avoids the thermal melting and shrinkage of the extract on one hand, and realizes the recycling of the solvent on the other hand, thereby really realizing the optimization of the zero-emission column chromatography separation technology, which mainly optimizes the multi-stage membrane separation technology, further purifying the content of specific components, and mainly aiming at the products with high requirements on the content of one or more effective components. The high-efficiency high-pressure-difference low-temperature continuous extraction, separation and concentration technology (HHLSE) is one of the global advanced extraction technologies at present, the whole extraction process adopts a physical mode and is carried out in a low-temperature state, and the maximum retention rate of the original substances is realized. Meanwhile, the low-temperature high-pressure-difference extraction effect is obviously higher than that of hot reflux extraction, so that each product extracted by the technology ensures high-activity components.

Example 2

A small molecular peptide multiple biological nutrient is prepared from the following raw materials in parts by weight:

51g of small molecular peptide, 8g of vitamin, 13 g of emulsifier, 38g of starch sodium octenylsuccinate, 8g of common yam rhizome, 6g of dendrobium, 11g of lily and 10g of perilla.

Furthermore, the small molecule peptide is a mixture of small molecule casein phosphopeptide and collagen peptide with the molecular weight less than 600 daltons in equal proportion.

Furthermore, the vitamin is a mixture of vitamin A, vitamin PP and vitamin K2 in equal proportion.

Furthermore, the emulsifier is an equal ratio mixture of oleic acid monoglyceride and sodium stearoyl lactylate.

The preparation method is the same as example 1.

Example 3

A small molecular peptide multiple biological nutrient is prepared from the following raw materials in parts by weight:

61g of small molecular peptide, 7g of vitamin, 13 g of emulsifier, 33g of octenyl succinic acid starch sodium, 10g of common yam rhizome, 4g of dendrobium, 15g of lily and 9g of perilla.

Furthermore, the small molecule peptide is a mixture of small molecule casein phosphopeptide and collagen peptide with the molecular weight less than 600 daltons in equal proportion.

Further, the vitamins are equal ratio mixture of vitamin A, vitamin B2, vitamin B4, vitamin C and inositol.

Further, the emulsifier is polyglyceryl fatty acid ester.

The preparation method is the same as example 1.

It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.