Transfer device of immunoassay analyzer

文档序号:254995 发布日期:2021-11-16 浏览:3次 中文

阅读说明:本技术 免疫分析仪的转移装置 (Transfer device of immunoassay analyzer ) 是由 王爱民 玄哲玉 于 2021-08-12 设计创作,主要内容包括:本发明公开了一种免疫分析仪的转移装置,包括分析区,所述分析区包括供料斗区、反应容器回收区、测光区、转移装置、清洁盘、样品搬运区、样品移液器、试剂盘、试剂移液器和反应盘,清洁盘上设置夹取处五,反应盘上设置夹取处二、夹取处三和夹取处四,供料斗区上设置夹取处一,测光区上设置夹取处六,反应容器回收区上设置回收处,转移装置内设置旋转机构。本发明可以轻易调整位置,通过在抓取反应容器时使用两侧不同的压力夹取反应容器可以很稳定地夹取,还能通过传感器检测到未抓取到反应容器等夹取状态。(The invention discloses a transfer device of an immunoassay analyzer, which comprises an analysis area, wherein the analysis area comprises a feeding hopper area, a reaction container recovery area, a light measuring area, a transfer device, a cleaning disc, a sample carrying area, a sample pipettor, a reagent disc, a reagent pipettor and a reaction disc, a fifth clamping part is arranged on the cleaning disc, a second clamping part, a third clamping part and a fourth clamping part are arranged on the reaction disc, a first clamping part is arranged on the feeding hopper area, a sixth clamping part is arranged on the light measuring area, a recovery part is arranged on the reaction container recovery area, and a rotating mechanism is arranged in the transfer device. The invention can easily adjust the position, can clamp the reaction vessel stably by using different pressure clamps at two sides when the reaction vessel is grabbed, and can detect the clamping state of the reaction vessel and the like which are not grabbed by a sensor.)

1. A transfer device of an immunoassay analyzer comprises an analysis area, and is characterized in that the analysis area comprises a feeding hopper area (11), a reaction vessel recovery area (12), a light measuring area (13), a transfer device (14), a BF cleaning disc (15), a sample carrying area (16), a sample pipettor (17), a reagent disc (18), a reagent pipettor (19) and a reaction disc (3), wherein a first clamping position (46) is arranged on the BF cleaning disc (15), a second clamping position (43), a third clamping position (44) and a fourth clamping position (45) are arranged on the reaction disc (3), a first clamping position (42) is arranged on the feeding hopper area (11), a sixth clamping position (47) is arranged on the light measuring area (13), a recovery position (41) is arranged on the reaction vessel recovery area (12), a rotating mechanism (4) is arranged in the transfer device (14), and the transfer device (14) comprises a transfer mechanism (10) and a chuck mechanism (20), the upper end of the transfer mechanism (10) is provided with a chuck mechanism (20), the transfer mechanism (10) is internally provided with a rotating mechanism (4), a lifting mechanism and a driving mechanism, and the chuck mechanism (20) comprises a clamping area (21), a clamping operation area (22), a clamping state detection area (23), a clamping moving area (24) and a sensor area (25).

2. The transfer device of an immunoassay analyzer according to claim 1, wherein the clamping area (21) comprises a clamping area mounting plate (21g), a clamping area (21a), a clamping support (21b), a fulcrum (21c), a tension spring (21f), a first torsion spring (21d) and a second torsion spring (21e), and the lower end of the clamping area mounting plate (21g) is provided with the clamping area (21a), the clamping support (21b), the fulcrum (21c), the tension spring (21f), the first torsion spring (21d) and the second torsion spring (21 e).

3. The transfer device of an immunoassay analyzer according to claim 2, wherein the gripper (21a) is (R) -shaped.

4. The transfer device of an immunoassay analyzer according to claim 2, wherein the radius of the gripper (21a) is smaller than the radius of the reaction vessel, the pressing portion of the gripper (21a) is located at an outer position of the center of the reaction vessel, the pressing force of the first torsion spring (21d) and the second torsion spring (21e) stabilizes the position of the gripper, and the tension spring (21f) assists the pressing force of the first torsion spring (21d) and the second torsion spring (21 e).

5. The transfer device of an immunoassay analyzer according to claim 1, wherein the grasping operation section (22) comprises a cam (22a), a motor (22b) and a bracket (22c), the cam (22a) is located in the middle of the grasping support (21b), the grasping support (21b) is rotated by a first torsion spring (21d), a second torsion spring (21e) and a tension spring (21f) with the fulcrum (21c) as a rotation axis, and the motor (22b) is mounted on the bracket (22 c).

6. The transfer device of an immunoassay analyzer according to claim 1, wherein the grasping state detecting section (23) comprises a detecting plate (23a), a first sensor (23b), a second sensor (23c) and a sensor mounting plate (23d), and the detecting plate (23a) is mounted on the grasping support (21b) which is weak in pressure.

7. The transfer device for an immunoassay analyzer according to claim 1, wherein the grasping movement area (24) comprises a linear guide (24a), a linear pulse motor (24b), a rotation shaft (24c), a spring three (24d) and a spring four (24f), the grasping area mounting plate (21g) is mounted on the linear guide (24a), and the grasping area mounting plate (21g) is connected to the shaft portion of the linear pulse motor (24b) by preventing the rotation shaft (24 c).

8. The transfer device of an immunoassay analyzer according to claim 1, wherein the sensor section (25) comprises a transmissive origin sensor (25a) and a detection plate (25 b).

Technical Field

The invention relates to a transfer device, in particular to a transfer device of an immunoassay analyzer.

Background

In the immunoassay analyzer, a small amount of a sample is mixed with a plurality of reagents including magnetic particles and an enzyme marker to cause an antigen-antibody reaction, and then a chemiluminescent substrate is added to perform immunoassay based on the intensity of luminescence. In the immunoassay analyzer, a series of immunoassay steps of BF cleaning in which a sample and a substance which reacts by mixing a magnetic particle and a plurality of reagents including an enzyme label and binds to the magnetic particle and reacts, and BF separation from the substance which does not bind and does not react, and luminescence generated by adding a luminescent substrate solution to the reaction substance and measuring the luminosity thereof can be performed in a reaction vessel.

In the conventional immunoassay analyzer, since it is necessary to accurately grasp a reaction vessel at a place other than a reaction vessel recovery area, although a transfer device and other instruments need to be subjected to a difficult positional adjustment, there is a case where a grasping error is caused by no adjustment, and the present invention provides a highly reliable transfer device capable of accurately transferring a reaction vessel from a feed hopper area to a reaction disk, a BF cleaning disk, a photometric area, and a reaction vessel recovery area.

Disclosure of Invention

The present invention is directed to a transfer device of an immunoassay analyzer, which solves the above problems of the related art.

In order to achieve the purpose, the invention provides the following technical scheme:

the utility model provides an immunoassay appearance's transfer device, including the analysis district, the analysis district includes the feed fill district, reaction vessel recovery area, the photometry area, transfer device, clean dish, sample transport district, the sample pipettor, the reagent dish, reagent pipettor and reaction disc, it presss from both sides and gets a five to set up on the clean dish, it gets a two to set up on the reaction disc to press from both sides, press from both sides and get a three and press from both sides and get a four, it gets a first to set up on the feed fill district to press from both sides, it gets a six to set up on the photometry area to press from both sides, set up recovery department on the reaction vessel recovery area, set up rotary mechanism in the transfer device, transfer device includes transfer mechanism and chuck mechanism, transfer mechanism upper end installation chuck mechanism, set up rotary mechanism in the transfer mechanism, elevating system and actuating mechanism, chuck mechanism is including pressing from both sides and getting the district, press from both sides and get the operation zone, press from both sides and get the state detection zone, press from both sides and get removal district and sensor district.

As a further scheme of the invention: the clamping area comprises a clamping area mounting plate, a first clamping and clamping support, a fulcrum, a tension spring, a first torsion spring and a second torsion spring, and the clamping area mounting plate is mounted at the lower end of the clamping area mounting plate and clamped with the first clamping and clamping support, the fulcrum, the tension spring, the first torsion spring and the second torsion spring.

As a still further scheme of the invention: the clip is shaped.

As a still further scheme of the invention: the clamping radius is smaller than that of the reaction container, the clamping pressing position is located at the outer side position of the center of the reaction container, the clamping position of the reaction container is stable due to the pressure of the first torsion spring and the second torsion spring, and the first torsion spring and the second torsion spring assist in pressure.

As a still further scheme of the invention: the clamping operation area comprises a cam, a motor and a bracket, the cam is located in the middle of the clamping support, the clamping support rotates through a first torsion spring, a second torsion spring and a tension spring by taking a fulcrum as a rotating shaft, and the motor is installed on the bracket.

As a still further scheme of the invention: the clamping state detection area comprises a detection plate, a first sensor, a second sensor and a sensor mounting plate, and the detection plate is mounted on the clamping support with weak pressure.

As a still further scheme of the invention: the clamping moving area comprises a linear guide rail, a linear pulse motor, a rotating shaft, a spring III and a spring IV, the clamping area mounting plate is arranged on the linear guide rail, and the clamping area mounting plate is connected with the shaft part of the linear pulse motor through the rotating shaft.

As a still further scheme of the invention: the sensor area includes a transmissive origin sensor and a detection plate.

Compared with the prior art, the invention has the beneficial effects that:

the invention can easily adjust the position, can clamp the reaction vessel stably by using different pressure clamps at two sides when the reaction vessel is grabbed, and can detect the clamping state of the reaction vessel and the like which are not grabbed by a sensor.

Drawings

FIG. 1 is a schematic view showing the structure of an analysis region in a transfer device of an immunoassay analyzer.

FIG. 2 is a schematic view showing the structure of a reaction vessel gripped by a transfer device in a transfer device of an immunoassay analyzer.

Fig. 3 is a schematic view of the structure of a transfer device in the transfer device of the immunoassay analyzer.

Fig. 4 is a schematic structural view of a chuck mechanism in a transfer device of an immunoassay analyzer.

FIG. 5 is a schematic view showing the structure of a grasping area in a transfer device of an immunoassay analyzer.

Fig. 6 is a schematic view showing a structure of a gripper in a transfer device of an immunoassay analyzer.

FIG. 7 is a schematic view showing the structure of a grasping operation area in a transfer device of an immunoassay analyzer.

Fig. 8 is a schematic view showing the configuration of a gripping state detection area in a transfer device of an immunoassay analyzer.

Fig. 9 is a schematic view showing the structure of a cam in a transfer device of an immunoassay analyzer.

FIG. 10 is a schematic view showing the structure of a detection plate in a transfer device of an immunoassay analyzer.

FIG. 11 is a schematic view showing a structure of clamping a reaction vessel in a transfer device of an immunoassay analyzer.

FIG. 12 is a schematic view showing a configuration in which a reaction container is not grasped in a transfer device of an immunoassay analyzer.

Fig. 13 is a schematic structural diagram of a gripping and moving area and a gripping and moving to an origin sensor area in a transfer device of an immunoassay analyzer.

FIG. 14 is a schematic view showing the structure of a gripping and moving area in a transfer device of an immunoassay analyzer.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1 to 14, in an embodiment of the present invention, a transfer device of an immunoassay analyzer includes an analysis area, the analysis area includes a feeding hopper area 11, a reaction container recovery area 12, a light measuring area 13, a transfer device 14, a BF cleaning tray 15, a sample handling area 16, a sample pipettor 17, a reagent tray 18, a reagent pipettor 19, and a reaction tray 3, a fifth clamping position 46 is disposed on the BF cleaning tray 15, a second clamping position 43, a third clamping position 44, and a fourth clamping position 45 are disposed on the reaction tray 3, a first clamping position 42 is disposed on the feeding hopper area 11, a sixth clamping position 47 is disposed on the light measuring area 13, a recovery position 41 is disposed on the reaction container recovery area 12, a rotating mechanism 4 is disposed in the transfer device 14, the transfer device 14 includes a transfer mechanism 10 and a chuck mechanism 20, the chuck mechanism 20 is disposed at an upper end of the transfer mechanism 10, a rotating mechanism 4, a lifting mechanism, and a driving mechanism are disposed in the transfer mechanism 10, the chuck mechanism 20 includes a gripping area 21, a gripping operation area 22, a gripping state detection area 23, a gripping movement area 24, and a sensor area 25;

the clamping area 21 comprises a clamping area mounting plate 21g, a clamping area 21a, a clamping support 21b, a fulcrum 21c, a tension spring 21f, a first torsion spring 21d and a second torsion spring 21e, and the lower end of the clamping area mounting plate 21g is provided with the clamping area 21a, the clamping support 21b, the fulcrum 21c, the tension spring 21f, the first torsion spring 21d and the second torsion spring 21 e;

the reaction vessel is cylindrical, the gripper 21a is R-shaped, the radius of the gripper 21a is smaller than that of the reaction vessel, and the pressing part of the gripper 21a is positioned at the outer side position of the center of the reaction vessel, so that the reaction vessel can be stably gripped;

the clamp 21a rotates around a pivot 21c, and presses the reaction vessel with a constant force by a first torsion spring 21d and a second torsion spring 21e, and the clamp bracket 21b has the function of a connecting rod;

the pressure of the first torsion spring 21d and the second torsion spring 21e enables the clamping position of the reaction container to be stable, and the tension spring 21f is the pressure of the auxiliary torsion springs 21d and 21 e;

the gripping operation area 22 includes a cam 22a, a motor 22b, and a carriage 22 c;

the cam 22a is positioned in the middle of the gripping bracket 21b, the gripping bracket 21b rotates by the torsion spring 21d, the torsion spring 21e and the tension spring 21f with the fulcrum 21c as a rotation axis, the cam 22a is continuously pressed by the gripping bracket 21b, the cam 22a can freely rotate because the hole opened at the center is engaged with the shaft of the motor 22b, the motor 22b is mounted on the bracket 22c,

the gripping state detection area 23 includes a detection plate 23a, a first sensor 23b, a second sensor 23c and a sensor mounting plate 23d,

the detection plate 23a is arranged on the clamping bracket 21b with weak pressure, the detection plate 23a is arranged on a sensor mounting plate 23d at a detectable position, the first sensor 23b and the second sensor 23c are transmission type sensors arranged in a light projection area and a back light receiving area, the sensors are opened if light from the light projection position is received at the light receiving position, and the sensors are closed if light from the light projection position is not received at the light receiving position due to a shielding object;

when the motor 22b is rotated and the gripper 21a grips and releases the reaction vessel, there are 3 positional relationships, and the operations of the respective zones and the detection states of the first sensor 23b and the second sensor 23c will be described below;

first, the motor 22b rotates, the clamping brackets 21b of the two sides are pressed by the cylinder area outside the cam 22a, the clamping 21a is in the maximum opening state, the torque of the motor 22b is larger than the torque generated by the first torsion spring 21d, the second torsion spring 21e and the tension spring 21f, therefore, the clamping detection plate 21a can be opened to the maximum extent, and at the moment, the light of the first sensor 23b and the second sensor 23c can be shielded by the first motor 23 a;

secondly, the outer cylinder area presses the clamping support 21b to enable the cam 22a to rotate 90 degrees, the cam 22a is displaced to the inner cylinder area at the position of the clamping support 21b with strong pressure, the cam 22a is displaced to the cutting area at the position of the clamping support 21b with weak pressure, the relative relation between the clamping support 21a and the reaction container is not changed all the time as the clamping support 21b with strong pressure is displaced to the position connected with the inner cylinder area of the cam 22a, in addition, the clamping support 21a is always pressed against the reaction container before the clamping support 21b with weak pressure reaches the cutting area of the cam 22a, and the pressure is smaller than the clamping support 21a on the back, so the position of the reaction container is stable, and at the moment, no light is blocked by the sensor two 23c and the sensor one 23b due to the gap of the detection plate 23 a;

thirdly, because the clamping support 21b with strong pressure moves to a position connected with a cylindrical area on the inner side of the cam 22a, the relative relationship between the clamping support 21a and the reaction vessel is not changed all the time, in addition, the clamping support 21b with weak pressure reaches a cutting area of the cam 22a, the sensor two 23c does not block light, and the sensor one 23b blocks light because the optical axis of the projected light and the received light deviates from the gap of the detection plate 23 a;

the gripping movement area 24 includes a linear guide rail 24a, a linear pulse motor 24b, a rotation shaft 24c, a spring three 24d, and a spring four 24 f;

a gripping area mounting plate 21g on which the gripping area 21, the gripping operation area 22, and the gripping state detection area 23 are mounted is mounted on the linear guide rail 24a, the gripping area mounting plate 21g is connected to the shaft portion of the linear pulse motor 24b through a rotation preventing shaft 24c, a portion of the shaft of the linear pulse motor 24b has a place cut into 2 planes, the rotation preventing shaft 24c is provided in the cutting area, the thickness of the rotation preventing shaft 24c is slightly smaller than the width of the place where the shaft portion of the linear pulse motor 24b is cut into 2 planes, and thus a rattling sound occurs when moving, a linear pulse motor mounting plate is provided with a spring three 24d and a spring four 24f for eliminating rattling, and the sensor area 25 includes origin sensors 25a and 25b of a transmission type;

moving the reaction vessel from the first clamping position 42 on the feeding hopper area 11 to the second clamping position 43 on the reaction tray 3, rotating the transfer mechanism 10 to the first clamping position 42 where the reaction vessel is placed according to the adjustment value of the first clamping position 42 by an instruction, moving the transfer mechanism 10 back and forth according to the adjustment value of the first clamping position 42, performing the next operation according to another instruction, opening the clamping position 21a to the maximum, lowering the transfer mechanism 10, performing the clamping operation, raising the transfer mechanism 10 to the top dead center, moving the reaction vessel to the second clamping position 43, rotating the transfer mechanism 10 according to the adjustment value of the second clamping position 43, moving the reaction vessel back and forth according to the adjustment value of the second clamping position 43, lowering the transfer mechanism 10, opening the clamping position 21a to the maximum, placing the reaction vessel on the reaction tray 3, moving the reaction vessel to a designated place by the transfer device 14 according to the measurement step, and finally, after the light measurement of the light measurement area 13 is finished, the reaction container is moved to a reaction container recovery area 12 for recovery.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

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