阅读说明：本技术 一种级联转化快速组装缩二脲-胍衍生物的制备方法 (Preparation method for rapidly assembling biuret-guanidine derivative through cascade conversion ) 是由 杨振 南敏伦 谷伟玲 刘建璇 赫玉芳 张红岩 王淑琴 王磊 于 2021-05-26 设计创作，主要内容包括：本发明涉及有机化合物合成技术,公开了一种缩二脲胍衍生物及其合成方法。所述缩二脲胍衍生物的结构如式(Ⅰ)所示,在式(Ⅰ)中X选自O,S；R选自C1-C7的直链、支链、环状烷基或烯基,取代或未取代的C6-C12芳基,或者取代或未取代的含有氮原子、氧原子和硫原子中的至少一种的杂环基团；该类化合物的合成方法是在没有催化剂的条件下,异氰酸酯及异硫氰酸酯类化合物与1,1,3,3-四甲基胍(TMG)快速反应。本发明方法的产率较高,反应体系简单,反应条件温和,用料来源广泛,成本低廉且环境友好。(The invention relates to the organic compound synthesis technology, and discloses a biuret guanidine derivative and a synthesis method thereof. The structure of the biuret guanidine derivative is shown as a formula (I), wherein X is selected from O and S; r is selected from C1-C7 straight chain, branched chain, cyclic alkyl or alkenyl, substituted or unsubstituted C6-C12 aryl, or substituted or unsubstituted heterocyclic group containing at least one of nitrogen atom, oxygen atom and sulfur atom; the synthesis method of the compound is that under the condition of no catalyst, isocyanate and isothiocyanate compounds react with 1, 1, 3, 3-Tetramethylguanidine (TMG) rapidly. The method has the advantages of high yield, simple reaction system, mild reaction conditions, wide material sources, low cost and environmental friendliness.)