阅读说明：本技术 一种双侧耳软骨鼻尖三角塑形方法 (Bilateral ear cartilage nose tip triangle shaping method ) 是由 王恒 金磊 于 2020-06-23 设计创作，主要内容包括：本发明公开了一种双侧耳软骨鼻尖三角塑形方法,包括如下步骤：S1取骨：在无菌环境下取得自体软骨；S2处理：将取得的所述自体软骨依次进行脱脂、脱钙、脱蛋白和灭菌处理；S21将所述同种异体软骨浸入氯仿和甲醇混合液体中6-24小时；S22将上述步骤S21处理后的同种异体软骨加入盐酸溶液中,持续搅拌8-12小时；S23将上述步骤S22处理后的同种异体软骨浸入TritonX-100和氨水混合溶液中作用2-72小时；S24将上述步骤S23处理后的所述同种异体软骨冷冻干燥、灭菌处理；S3雕琢；S4鼻尖三角塑形。本发明通过鼻梁段和鼻中隔两侧的设计,使得假体与鼻骨紧密接触,自体软骨通过假体和长方形形状软骨限位作用,不会位移或磨损,防止鼻假体移动、脱落、溃烂,防止术后病人的疼痛。(The invention discloses a bilateral ear cartilage nose tip triangle shaping method, which comprises the following steps: s1 bone extraction: obtaining autologous cartilage in a sterile environment; and S2 processing: sequentially carrying out degreasing, decalcification, deproteinization and sterilization treatment on the obtained autologous cartilage; s21, immersing the allogeneic cartilage in a mixed liquid of chloroform and methanol for 6-24 hours; s22, adding the allogeneic cartilage processed in the step S21 into a hydrochloric acid solution, and continuously stirring for 8-12 hours; s23, immersing the allogeneic cartilage processed in the step S22 in a mixed solution of TritonX-100 and ammonia water for 2-72 hours; s24, freeze-drying and sterilizing the allogeneic cartilage processed in the step S23; s3 carving; s4 triangle shaping of nose tip. The invention enables the prosthesis to be in close contact with the nasal bone through the design of the two sides of the nose bridge section and the nasal septum, the autologous cartilage cannot be displaced or abraded through the limiting effect of the prosthesis and the rectangular cartilage, the nasal prosthesis is prevented from moving, falling off and ulcerating, and the pain of a patient after operation is prevented.)

1. A bilateral ear cartilage nose tip triangle shaping method is characterized by comprising the following steps:

s1 bone extraction:

obtaining autologous cartilage in a sterile environment;

and S2 processing:

sequentially carrying out degreasing, decalcification, deproteinization and sterilization treatment on the obtained autologous cartilage;

s21, immersing the allogeneic cartilage in a mixed liquid of chloroform and methanol for 6-24 hours;

s22, adding the allogeneic cartilage processed in the step S21 into a hydrochloric acid solution, and continuously stirring for 8-12 hours;

s23, immersing the allogeneic cartilage processed in the step S22 in a mixed solution of TritonX-100 and ammonia water for 2-72 hours;

s24, freeze-drying and sterilizing the allogeneic cartilage processed in the step S23;

s3 carving:

carving the treated autologous cartilage into two double-layer triangular cartilage and two small rectangular cartilage;

s4 nose tip triangle shaping:

firstly, lifting the skin on the nose in an operation, fixing two layers of triangular cartilage on two sides of the nasal septum cartilage, and then fixing two small pieces of rectangular cartilage at the front foot position of the nasal septum cartilage, wherein the two small pieces of rectangular cartilage are respectively supported with the bottoms of the two layers of triangular cartilage;

fixing a prosthesis at the position of a nose quilt of the nasal septum cartilage, wherein the front end of the prosthesis is respectively fixed with the upper ends of the two layers of triangular cartilage;

s5, covering the skin cap to complete the triangle shaping of the nose tip.

2. The bilateral auricular cartilage nose tip trigonal shaping method according to claim 1, wherein the volume ratio of chloroform to methanol in the chloroform-methanol mixture of step S21 is 1: 1, the concentration of the hydrochloric acid solution is 0.5-0.6mol/L, the volume percentage of TritonX-100 in the mixed solution of TritonX-100 and ammonia water is 0.1-2%, the mass percentage of ammonia is 0.3%, and freeze drying means that the allogenic cartilage is put into a freeze dryer at-72 to-80 ℃ for freeze drying for 24-48 h.

3. The bilateral auricular cartilage nose tip trigonal shaping method of claim 1, wherein the sterilization treatment of step S24 is to package and seal the allogeneic cartilage with a plastic bag and put the packaged allogeneic cartilage into an ethylene oxide sterilizer for sterilization, wherein the mass concentration of ethylene oxide is controlled to be 480mg/L to 520mg/L, the sterilization temperature is controlled to be 38 ℃ to 42 ℃, the sterilization humidity is 45% to 55%, the sterilization time is 3h to 4h, and the sterilization strength is 1500mg/h L to 2000mg/h L.

4. The method for bilateral auricular chondral-tip trigonal shaping of claim 1, wherein the autologous cartilage of step S1 is bilateral auricular cartilage.

Technical Field

The invention relates to the technical field of plastic shaping, in particular to a bilateral ear cartilage nose tip triangle shaping method.

Background

The nasal plastic (cosmetic) operation is an operation that changes the height and shape of the nose by implanting appropriate materials to coordinate with other parts of the face, and is the most common operation in the plastic surgery field.

In medicine, there are many kinds of nasal plastic materials, such as medical silicon rubber, autologous cartilage, allogeneic cartilage, animal tendon or ligament, varicosity (polytetrafluoroethylene), hyaluronic acid, etc. The nose bridge prosthesis is prepared by a plurality of methods, wherein autologous cartilage is sourced from the self, so that rejection phenomenon and sensitization are avoided, but shaping is difficult in the preparation process, and pain of patients is increased. The tendon and ligament of allogeneic cartilage animal are used as raw materials, and the composition and structure of the tendon and ligament are similar to those of human tissues, so that the tendon and ligament has good biocompatibility, can not cause immunological rejection reaction when implanted, can induce tissue regeneration, but needs to be treated by a series of biochemical techniques, and has a complex manufacturing process. The solid silicon rubber nose-humping material is a main medical prosthesis nose-humping material because of no toxicity and harmlessness and relatively stable histocompatibility, is easy to shape in the manufacturing process, but is easy to shift and wear after the silicon rubber implant is implanted into a body, and the shaping stability of the nose tip is not high.

Disclosure of Invention

Based on the technical problems in the background art, the invention provides a bilateral ear cartilage nose tip triangle shaping method.

The invention provides a bilateral ear cartilage nose tip triangle shaping method, which comprises the following steps:

s1 bone extraction:

obtaining autologous cartilage in a sterile environment;

and S2 processing:

sequentially carrying out degreasing, decalcification, deproteinization and sterilization treatment on the obtained autologous cartilage;

s21, immersing the allogeneic cartilage in a mixed liquid of chloroform and methanol for 6-24 hours;

s22, adding the allogeneic cartilage processed in the step S21 into a hydrochloric acid solution, and continuously stirring for 8-12 hours;

s23, immersing the allogeneic cartilage processed in the step S22 in a mixed solution of TritonX-100 and ammonia water for 2-72 hours;

s24, freeze-drying and sterilizing the allogeneic cartilage processed in the step S23;

s3 carving:

carving the treated autologous cartilage into two double-layer triangular cartilage and two small rectangular cartilage;

s4 nose tip triangle shaping:

firstly, lifting the skin on the nose in an operation, fixing two layers of triangular cartilage on two sides of the nasal septum cartilage, and then fixing two small pieces of rectangular cartilage at the front foot position of the nasal septum cartilage, wherein the two small pieces of rectangular cartilage are respectively supported with the bottoms of the two layers of triangular cartilage;

fixing a prosthesis at the position of a nose quilt of the nasal septum cartilage, wherein the front end of the prosthesis is respectively fixed with the upper ends of the two layers of triangular cartilage;

s5, covering the skin cap to complete the triangle shaping of the nose tip.

Preferably, the volume ratio of chloroform to methanol in the chloroform-methanol mixture of step S21 is 1: 1, the concentration of the hydrochloric acid solution is 0.5-0.6mol/L, the volume percentage of TritonX-100 in the mixed solution of TritonX-100 and ammonia water is 0.1-2%, the mass percentage of ammonia is 0.3%, and freeze drying means that the allogenic cartilage is put into a freeze dryer at-72 to-80 ℃ for freeze drying for 24-48 h.

Preferably, the sterilization treatment of step S24 is to package and seal the allogeneic cartilage with a plastic bag, and place the packaged allogeneic cartilage into an ethylene oxide sterilizer for sterilization, wherein the mass concentration of ethylene oxide is controlled to be 480mg/L to 520mg/L, the sterilization temperature is controlled to be 38 ℃ to 42 ℃, the sterilization humidity is 45% to 55%, the sterilization time is 3h to 4h, and the sterilization strength is 1500 mg/h.l to 2000 mg/h.l.

Preferably, the autologous cartilage of step S1 is bilateral auricular cartilage.

According to the method for shaping the soft ear bone and the nasal tip triangle at the two sides, the nose bridge section and the two sides of the nasal septum are designed, so that the prosthesis is in close contact with the nasal bone, the autologous cartilage cannot be displaced or abraded through the limiting effect of the prosthesis and the rectangular cartilage, the nasal prosthesis is prevented from moving, falling off and ulcerating, and the pain of a postoperative patient is prevented.

Detailed Description

The following will clearly and completely describe the technical solutions in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.

A bilateral ear cartilage nose tip triangle shaping method comprises the following steps:

s1 bone extraction:

obtaining autologous cartilage in a sterile environment;

and S2 processing:

sequentially carrying out degreasing, decalcification, deproteinization and sterilization treatment on the obtained autologous cartilage;

s21, immersing the allogeneic cartilage in a mixed liquid of chloroform and methanol for 6-24 hours;

s22, adding the allogeneic cartilage processed in the step S21 into a hydrochloric acid solution, and continuously stirring for 8-12 hours;

s23, immersing the allogeneic cartilage processed in the step S22 in a mixed solution of TritonX-100 and ammonia water for 2-72 hours;

s24, freeze-drying and sterilizing the allogeneic cartilage processed in the step S23;

s3 carving:

carving the treated autologous cartilage into two double-layer triangular cartilage and two small rectangular cartilage;

s4 nose tip triangle shaping:

firstly, lifting the skin on the nose in an operation, fixing two layers of triangular cartilage on two sides of the nasal septum cartilage, and then fixing two small pieces of rectangular cartilage at the front foot position of the nasal septum cartilage, wherein the two small pieces of rectangular cartilage are respectively supported with the bottoms of the two layers of triangular cartilage;

fixing a prosthesis at the position of a nose quilt of the nasal septum cartilage, wherein the front end of the prosthesis is respectively fixed with the upper ends of the two layers of triangular cartilage;

s5, covering the skin cap to complete the triangle shaping of the nose tip.

In the present invention, the volume ratio of chloroform to methanol in the chloroform-methanol mixture at step S21 is 1: 1, the concentration of the hydrochloric acid solution is 0.5-0.6mol/L, the volume percentage of TritonX-100 in the mixed solution of TritonX-100 and ammonia water is 0.1-2%, the mass percentage of ammonia is 0.3%, and the freeze drying refers to that the allogeneic cartilage is put into a freeze dryer at-72 ℃ to-80 ℃ for freeze drying for 24-48 h.

In the invention, the sterilization treatment of the step S24 is to package and seal the allogeneic cartilage with a plastic bag and then put the allogeneic cartilage into an ethylene oxide sterilizer for sterilization, wherein the mass concentration of the ethylene oxide is controlled to be 480-520 mg/L, the sterilization temperature is controlled to be 38-42 ℃, the sterilization humidity is 45-55%, the sterilization time is 3-4 h, and the sterilization strength is 1500-2000 mg/h.L.

In the present invention, the autologous cartilage in step S1 is the cartilage of both lateral ears.

The invention comprises the following steps: bone taking: obtaining autologous cartilage in a sterile environment; and (3) treatment: sequentially carrying out degreasing, decalcification, deproteinization and sterilization treatment on the obtained autologous cartilage; immersing the allogenic cartilage into a mixed liquid of chloroform and methanol for 6-24 hours; adding the allogeneic cartilage treated in the step into a hydrochloric acid solution, and continuously stirring for 8-12 hours; immersing the allogeneic cartilage treated in the step into a mixed solution of TritonX-100 and ammonia water for 2-72 hours; freeze drying and sterilizing the allogeneic cartilage treated in the step; carving: carving the treated autologous cartilage into two double-layer triangular cartilage and two small rectangular cartilage; the method comprises the following steps of performing nasal tip triangular shaping, namely, firstly, lifting the skin on a nose in an operation, fixing two layers of triangular cartilage on two sides of the nasal septum cartilage, and then fixing two small rectangular cartilage at the front foot position of the nasal septum cartilage, wherein the two small rectangular cartilage are respectively supported with the bottoms of the two layers of triangular cartilage; fixing a prosthesis at the position of a nose quilt of the nasal septum cartilage, wherein the front end of the prosthesis is respectively fixed with the upper ends of the two layers of triangular cartilage; covering the skin to complete the triangular shaping of the nose tip.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.