阅读说明：本技术 中药组合物、制备方法及中药制剂 (Traditional Chinese medicine composition, preparation method and traditional Chinese medicine preparation ) 是由 高补旺 高翠红 于 2019-09-26 设计创作，主要内容包括：本发明涉及中药领域,特别涉及一种中药组合物、制备方法及中药制剂。该中药组合物及中药制剂中有党参,海螵蛸,磁石,肉桂,熟地,麻黄,当归,丹参,生山药,生龙骨,牡蛎,山楂,川芎,银花,血蝎,龟胶,枸杞,砂仁,可以治疗股骨头坏死,骨质增生,骨质疏松,腰间盘突出腰间盘膨出、骨性关节炎、跌打损伤。该中药组合物及中药制剂治疗肾炎的总有效率达到96％以上,具有益肾健脾,活血祛瘀的功效,可用于肾炎的治疗,疗效稳定,无毒副作用,适于长期服用。(The invention relates to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition, a preparation method and a traditional Chinese medicine preparation. The traditional Chinese medicine composition and the traditional Chinese medicine preparation contain radix codonopsitis, cuttlebone, magnet, cinnamon, prepared rhizome of rehmannia, ephedra herb, angelica, salvia miltiorrhiza, raw yam, raw dragon bone, oyster, hawthorn, rhizoma ligustici wallichii, honeysuckle, scorpion, tortoise plastron glue, medlar and fructus amomi, and can treat femoral head necrosis, hyperosteogeny, osteoporosis, lumbar disc herniation, osteoarthritis and traumatic injury. The traditional Chinese medicine composition and the traditional Chinese medicine preparation have the total effective rate of treating nephritis of more than 96 percent, have the effects of tonifying kidney and spleen, promoting blood circulation and removing blood stasis, can be used for treating nephritis, have stable curative effect and no toxic or side effect, and are suitable for long-term administration.)

1. A Chinese medicinal composition for treating femoral head necrosis, hyperosteogeny, osteoporosis, lumbar disc herniation, osteoarthritis and traumatic injury is characterized by being prepared from the following raw materials in parts by weight:

15g of codonopsis pilosula, 25g of cuttlebone, 2g of magnetite, 8g of cinnamon, 9g of prepared rehmannia root, 25g of ephedra, 10g of angelica, 10g of salvia miltiorrhiza, 15g of raw Chinese yam, 15g of raw dragon bone, 10g of oyster, 10g of hawthorn, 10g of ligusticum wallichii, 10g of honeysuckle, 2g of sanguine scorpion, 5g of tortoise-plastron, 10g of medlar and 5g of fructus amomi.

2. The traditional Chinese medicine composition of claim 1, wherein the raw materials comprise: 15g of codonopsis pilosula, 25g of cuttlebone, 2g of magnetite, 8g of cinnamon, 9g of prepared rehmannia root, 25g of ephedra, 10g of angelica, 10g of salvia miltiorrhiza, 15g of raw Chinese yam, 15g of raw dragon bone, 10g of oyster, 10g of hawthorn, 10g of ligusticum wallichii, 10g of honeysuckle, 2g of sanguine scorpion, 5g of tortoise-plastron, 10g of medlar and 5g of fructus amomi.

3. A preparation method of a traditional Chinese medicine composition for treating femoral head necrosis, hyperosteogeny, osteoporosis, lumbar disc herniation, osteoarthritis and traumatic injury is characterized in that raw materials comprise 15g of codonopsis pilosula, 25g of cuttlebone, 2g of magnetite, 8g of cinnamon, 9g of prepared rhizome of rehmannia, 25g of ephedra, 10g of angelica, 10g of salvia miltiorrhiza, 15g of raw yam, 15g of raw keel, 10g of oyster, 10g of hawthorn, 10g of ligusticum wallichii, 10g of honeysuckle, 2g of hematoscorpion, 5g of tortoise plastron glue, 10g of medlar and 5g of fructus amomi;

distilling radix Angelicae sinensis and rhizoma Ligustici Chuanxiong with steam to collect volatile oil and residue, decocting the first residue with water, filtering, collecting first filtrate, mixing the first filtrate and the residue, and concentrating to obtain first fluid extract; the relative density of the first clear paste at 60-80 ℃ is 1.10-1.20;

heating and refluxing the astragalus and the achyranthes root by 60-95% ethanol, collecting an extracting solution, and concentrating to obtain a second clear paste; adding water into the second decoction dregs, decocting for the second time, filtering, collecting the second filtrate, and concentrating to obtain a third clear paste; the relative density of the second clear paste or the third clear paste at 60-80 ℃ is 1.10-1.20;

mixing the first fluid extract, the second fluid extract and the third fluid extract to obtain an extract; mixing the extract with the volatile oil.

4. The preparation method according to claim 3, wherein the steam distillation is specifically steam distillation for 1-2 times, each time for 2-8 hours; the refluxing is specifically performed for 1-3 times, and each time lasts for 1-3 hours; the first decoction is specifically that the mass volume ratio of the first decoction dregs to water is 1: 6-12 in g/mL; the second decoction is carried out specifically, wherein the mass volume ratio of the second decoction dregs to water is 1: 6-12 in g/mL.

5. The Chinese medicinal composition prepared by the preparation method according to any one of claims 3 to 6.

6. A Chinese medicinal preparation for treating nephritis, which is prepared from the Chinese medicinal composition of claim 1, 2 or 7 and pharmaceutically acceptable adjuvants.

7. The Chinese medicinal preparation according to claim 7, which is a granule, a capsule, a tablet, a pill or an oral liquid.

EXAMPLE 1 preparation of the Chinese medicinal composition

Weighing the following raw materials in proportion:

astragalus root 5g Chinese angelica root 120g

Achyranthes root 200g Ligusticum wallichii 2g

The preparation method comprises the following steps:

step 1: distilling radix Angelicae sinensis and rhizoma Ligustici Chuanxiong with steam for 4 hr to obtain volatile oil, collecting the distillate, decocting the residue with 6 times of water for 2 times (each time for 1 hr), filtering, mixing the filtrates, and concentrating under normal pressure or reduced pressure to obtain fluid extract with relative density of 1.1 at 80 deg.C;

step 2: adding 12 times volume percent of 75% ethanol into astragalus and achyranthes root, heating at 80 ℃, carrying out reflux extraction for 3 times, each time for 1 hour, filtering, combining ethanol extracting solutions, recovering ethanol from the extracting solutions, concentrating into clear paste, determining the relative density of the clear paste to be 1.1 at 80 ℃, adding 6 times volume percent of water into medicine residues, extracting for 3 times, each time for 1 hour, filtering, concentrating the filtrate under normal pressure or reduced pressure into clear paste, determining the relative density of the clear paste to be 1.1 at 80 ℃;

and step 3: mixing the fluid extracts obtained in step 1 and step 2, mixing, and vacuum drying to obtain extract powder;

and 4, step 4: and (3) adding the volatile oil obtained in the step (1) into the clear paste obtained in the step (3) to obtain the ointment.