阅读说明：本技术 一种供骨质疏松人群食用的含肽组合物及应用 (Peptide-containing composition for osteoporosis people to eat and application thereof ) 是由 张珍妮 于 2019-11-01 设计创作，主要内容包括：本发明属于保健食品、功能性食品技术领域,具体涉及一种供骨质疏松人群食用的含肽组合物及其应用。本发明所述组合物以牛骨低聚肽粉、驴骨胶原蛋白肽粉、葛根粉为主要成分,辅以天门冬酸钙、酪蛋白磷酸肽、维生素D等制备成一种供骨质疏松人群食用的含肽组合物,所述组合物具有强筋健骨、促进成骨细胞增值的功效,改善骨质疏松的效果显著,可用于制备辅助改善骨质疏松的产品。(The invention belongs to the technical field of health-care food and functional food, and particularly relates to a peptide-containing composition for people with osteoporosis and application thereof. The peptide-containing composition for people with osteoporosis is prepared from bovine bone oligopeptide powder, donkey bone collagen peptide powder and kudzu root powder as main components, and calcium aspartate, casein phosphopeptide, vitamin D and the like as auxiliary components, has the effects of strengthening tendons and bones and promoting osteoblast proliferation, has a remarkable effect of improving osteoporosis, and can be used for preparing products for assisting in improving osteoporosis.)

1. A peptide-containing composition for osteoporosis people is characterized by comprising bovine bone oligopeptide powder, donkey bone collagen peptide powder and kudzu root powder.

2. The peptide-containing composition according to claim 1, wherein the bovine bone oligopeptide powder is 3 to 4 parts, the donkey bone collagen peptide powder is 3 to 4 parts, and the kudzu root powder is 1 to 2 parts by weight.

3. The peptide-containing composition of claim 1 or 2, further comprising an adjuvant.

4. The peptide-containing composition of claim 3, wherein said excipients are calcium aspartate, casein phosphopeptide, and vitamin D.

5. The peptide-containing composition according to claim 4, wherein the calcium aspartate is in an amount of 0.01 to 0.5 parts by weight, the casein phosphopeptide is in an amount of 0.01 to 0.5 parts by weight, and the vitamin D is in an amount of 0.5 to 1 part by weight.

6. The peptide-containing composition of claim 1, wherein the bovine bone oligopeptide powder is prepared by the following preparation method:

fresh ox bone is used as a raw material, and the ox bone oligopeptide powder is prepared by the processes of crushing, cleaning, high-pressure extraction, enzymolysis by compound protease, filtering and concentration in sequence, with or without food additives of citric acid and food essence, mixing and drying.

7. The peptide-containing composition according to claim 1, wherein the donkey bone collagen peptide powder is prepared by the following preparation method:

the donkey bone collagen peptide powder is prepared by taking fresh donkey bones as raw materials, extracting under high pressure, carrying out enzymolysis on food additive complex enzyme, filtering, concentrating and drying.

8. Use of a peptide-containing composition according to any one of claims 1 to 7 in the manufacture of a product for aiding in the amelioration of osteoporosis.

Technical Field

The invention belongs to the technical field of health-care food and functional food, and particularly relates to a peptide-containing composition for people with osteoporosis and application thereof.

Background

Osteoporosis, is a group of bone diseases caused by various reasons, bone tissues have normal calcification, calcium salts and matrixes are in normal proportion, and metabolic bone lesions are characterized by the reduction of the amount of bone tissues in unit volume. Osteoporosis can occur in different sexes and at any age, but is most common in postmenopausal women and elderly men. Osteoporosis is divided into primary and secondary categories. Primary osteoporosis is classified into postmenopausal osteoporosis (type i), senile osteoporosis (type ii) and idiopathic osteoporosis (including juvenile type). Postmenopausal osteoporosis generally occurs in women within 5-10 years after menopause; senile osteoporosis generally refers to osteoporosis occurring in the elderly after age 70; however, idiopathic osteoporosis mainly occurs in adolescents, and the cause of the disease is unknown. Osteoporosis may be caused by a variety of diseases, called secondary osteoporosis, in addition to primary osteoporosis, which is primarily associated with menopause and aging.

Osteoporosis itself comprises three main categories of symptoms: (1) patients with pain may have soreness of the waist and back or soreness of the whole body, pain is aggravated or movement is limited when the load is increased, and turning over, sitting up and walking are difficult when the load is severe; (2) the patients with spinal deformity and osteoporosis have shortened height and hunchback. Vertebral compression fracture can cause thoracic deformity, abdominal compression, influence on heart and lung function, and the like; (3) fractures that occur non-traumatically or with minor trauma are brittle fractures, and are low energy or non-violent fractures, such as fractures that occur from falls from high or low standing heights or from other daily activities. Common sites of brittle fracture are thoracic, lumbar, hip, radial, distal ulna and proximal humerus. Pain caused by osteoporosis can reduce the life quality of a patient, spinal deformation and fracture can cause disability, the patient is limited in activity and cannot take care of life, the incidence rate of pulmonary infection and bedsore is increased, the life quality and the death rate of the patient are increased, and heavy economic burden is brought to individuals, families and the society.

At present, the treatment of osteoporosis is far from enough to increase the nutrient substances rich in calcium and protein, the ingestion of bone health supplements and proper exercise, and medicines need to be added according to the condition of a patient. Effective drug therapy can prevent and treat osteoporosis, including estrogen replacement therapy, calcitonin, selective estrogen receptor modulators, and bisphosphonates, but these drugs can prevent bone resorption but have particularly little effect on bone formation and may cause other systemic adverse effects.

Disclosure of Invention

In view of the above, the present invention aims to provide a peptide-containing composition for people with osteoporosis and its application, aiming at the problems in the prior art.

In order to realize the purpose of the invention, the invention adopts the following technical scheme:

a peptide-containing composition for osteoporosis people comprises Os bovis Seu Bubali oligopeptide powder, donkey bone collagen peptide powder, and radix Puerariae powder.

Preferably, the feed comprises, by weight, 3-4 parts of bovine bone oligopeptide powder, 3-4 parts of donkey bone collagen peptide powder and 1-2 parts of kudzu root powder.

Further, in some embodiments, the peptide-containing composition further comprises an adjuvant.

Wherein the auxiliary materials comprise calcium aspartate, casein phosphopeptide and vitamin D.

Preferably, the calcium aspartate is 0.01 to 0.5 part by weight, the casein phosphopeptide is 0.01 to 0.5 part by weight, and the vitamin D is 0.5 to 1 part by weight.

In some embodiments, the peptide-containing composition consists of 3 parts by weight of bovine bone oligopeptide powder, 4 parts by weight of donkey bone collagen peptide powder, 1 part by weight of kudzu root powder, 0.5 part by weight of calcium aspartate, 0.01 part by weight of casein phosphopeptide and 1 parts by weight of vitamin D.

In some embodiments, the peptide-containing composition consists of 4 parts by weight of bovine bone oligopeptide powder, 3 parts by weight of donkey bone collagen peptide powder, 2 parts by weight of kudzu root powder, 0.01 part by weight of calcium aspartate, 0.5 part by weight of casein phosphopeptide and 0.5 part by weight of vitamin D.

In some embodiments, the peptide-containing composition consists of 3 parts of bovine bone oligopeptide powder, 3 parts of donkey bone collagen peptide powder, 2 parts of kudzu root powder, 0.5 part of calcium aspartate, 0.5 part of casein phosphopeptide and 0.5 part of vitamin D in parts by weight.

In some embodiments, the peptide-containing composition consists of 4 parts by weight of bovine bone oligopeptide powder, 4 parts by weight of donkey bone collagen peptide powder, 1 part by weight of kudzu root powder, 0.01 part by weight of calcium aspartate, 0.01 part by weight of casein phosphopeptide and 0.5 part by weight of vitamin D.

The components of the peptide-containing compositions of the present invention are commercially available.

In some embodiments, the bovine bone oligopeptide powder is prepared by the following preparation method: fresh ox bone is used as a raw material, and the ox bone oligopeptide powder is prepared by the processes of crushing, cleaning, high-pressure extraction, enzymolysis by compound protease, filtering and concentration in sequence, with or without food additives of citric acid and food essence, mixing and drying.

In some embodiments, the donkey bone collagen peptide powder is prepared by the following preparation method:

the donkey bone collagen peptide powder is prepared by taking fresh donkey bones as raw materials, extracting under high pressure, carrying out enzymolysis on food additive complex enzyme, filtering, concentrating and drying.

The composition has the effects of strengthening muscles and bones, promoting osteoblast proliferation and improving osteoporosis, so that the invention provides the application of the composition in preparing products for assisting in improving osteoporosis.

The peptide-containing composition for people suffering from osteoporosis is prepared from bovine bone oligopeptide powder, donkey bone collagen peptide powder and kudzu root powder serving as main components and auxiliary materials, has the effects of strengthening tendons and bones, promoting osteoblast proliferation and improving osteoporosis, has a remarkable effect, and can be used for preparing products for assisting in improving osteoporosis.

Detailed Description

The invention discloses a peptide-containing composition for osteoporosis people and application thereof. Those skilled in the art can modify the process parameters appropriately to achieve the desired results with reference to the disclosure herein. It is expressly intended that all such similar substitutes and modifications which would be obvious to one skilled in the art are deemed to be included in the invention. While the methods and products of the present invention have been described in terms of preferred embodiments, it will be apparent to those of ordinary skill in the art that variations and modifications of the methods described herein, as well as other suitable variations and combinations, may be made to implement and use the techniques of the present invention without departing from the spirit and scope of the invention.

In order to further understand the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Unless otherwise specified, the reagents involved in the examples of the present invention are all commercially available products, and all of them are commercially available.