阅读说明：本技术 一种富含锶和硒的薯类粉条及制备方法 (Potato vermicelli rich in strontium and selenium and preparation method thereof ) 是由 于长河 于欣 吴彩霞 于 2021-05-16 设计创作，主要内容包括：本发明提供了一种富含锶和硒的薯类粉条及制备方法,属于生物医药应用技术领域。通过选择富锶区域的农作物,来增加饮食中的锶含量,降低体内钠元素含量,通过调整体液,来促使癌细胞变成正常细胞。通过选择嵩山颍河地区红薯,制成红薯粉条产品,本发明是一种药食同源产品,药物毒副作用小,病人可长期服用,并且携带方便,易于保存,具有广阔的应用前景。(The invention provides potato vermicelli rich in strontium and selenium and a preparation method thereof, belonging to the technical field of biomedical application. By selecting crops with strontium-rich regions, the content of strontium in the diet is increased, the content of sodium element in the body is reduced, and the cancer cells are promoted to become normal cells by adjusting body fluid. The sweet potato vermicelli product is prepared by selecting sweet potatoes in Songshan-Yinghe area, and the sweet potato vermicelli product is a medicine-food homologous product, has small toxic and side effects, can be taken by patients for a long time, is convenient to carry and easy to store, and has wide application prospect.)

1. The potato vermicelli rich in strontium and selenium and the preparation method are characterized in that the potato crop for preparing the potato vermicelli is the potato crop in the Yinghe river basin.

2. The potato vermicelli as claimed in claim 1, wherein the potato crop of the potato vermicelli is a potato crop of Songshan-Yinhe river basin.

3. The potato vermicelli rich in strontium and selenium and the preparation method thereof as claimed in claim 1 or 2, wherein the potato crop of the potato vermicelli is sweet potato of Songshan Yinhe river basin.

4. The potato vermicelli rich in strontium and selenium and the preparation method thereof as claimed in any one of claims 1-3, wherein sweet potatoes in Songshan Yinghe river basin and Tiegun yams produced in Jiaozhong selenium-rich soil are used for making the potato vermicelli.

5. A potato vermicelli rich in strontium and selenium and a preparation method thereof are characterized in that: the potato for making the potato vermicelli is subjected to ultramicro wall breaking treatment.

6. The potato vermicelli rich in strontium and selenium and the preparation method thereof as claimed in claim 6, wherein: the potatoes for making the potato vermicelli are fermented.

Technical Field

The invention relates to functional food, in particular to potato vermicelli rich in strontium and selenium and a preparation method thereof.

Background

Tumors are common diseases, while benign tumors are more common than malignant tumors, but malignant tumors, namely cancers, have the defects of rapid disease development, low cure rate and high death rate, and are one of the most serious diseases damaging human health.

According to data statistics, the incidence rate of breast cancer accounts for 7-10% of various malignant tumors of the whole body, and in many areas, the breast cancer exceeds uterine cancer, so that the breast cancer becomes one of the most common tumors which seriously affect the physical and mental health of women and even endanger life. The incidence of breast cancer is closely related to the genetic genes, living habits, common food, fertility conditions and the like of patients, and the incidence of breast cancer of different races and regions has obvious difference. The high incidence of breast cancer is mainly concentrated in north america, northern europe and oceania, and especially in white women. The middle-onset of breast cancer is concentrated in south america, south europe and israel. Asia is a low-incidence area of breast cancer. For example, the lifetime breast cancer incidence rate of caucasian women in the United states is 13.1%, i.e., on average, 1 person per 8-9 people may have breast cancer, while the breast cancer incidence rate of Asian women is 4-7%. According to WHO statistics, the number of new breast cancer is about 130 thousands of people every year and about 50 thousands of people die worldwide. The breast cancer in the large cities of Beijing, Shanghai, Tianjin and the like in China jumps over the first place of various cancers of women and has a trend of obvious rising. Among male cancer patients worldwide, liver cancer ranks sixth in proportion and mortality ranks second; among female cancer patients, liver cancer ranks seventh in proportion and mortality ranks sixth. In 2008, there were 748,300 new cases of liver cancer worldwide, and 695,900 patients with liver cancer died. Half of these new cases of liver cancer and death are in China. The highest incidence of liver cancer is mainly found in east asia, southeast asia, middle africa and west africa. The higher incidence of liver cancer in parts of Asia and sub-Saharan areas of Africa may be due to the prevalence of HBV in these areas, since 8% of the residents in these areas are chronically infected with HBV and 60% of liver cancer patients in developing countries are infected with HBV.

Investigation of the town of a celebrity card near New York by Jones, Andelin Hospital, USA, found that residents in the town had the same life habits as those in neighboring towns, but had significantly fewer cancer. The town edge is found to have a lake with a high potassium content through investigation. He combined with data analysis in more than 20 countries of the world found that cancer was less in areas with high potassium intake. Potassium is therefore considered to have a significant effect on cancer cells. Cytological studies have found that normal cells have potassium-sodium ratios as high as 10 times, but with the age, potassium contained in the body is easily separated from cell membranes, so that the intracellular sodium ratio is relatively high, and the environment is suitable for the propagation of cancer cells. This is a big cause of the increased chance of cancer in the elderly. Laboratory studies have also found that some cancer cells suddenly become normal if potassium is added to their culture.

The treatment of cancer is a major topic in today's medical community. In the known technology, at present, a variety of medicines for treating cancer at home and abroad are various, such as oral liquid, capsules, pills, external medicines and the like for treating cancer all have certain curative effects, but medicinal and edible foods for preventing and treating cancer do not exist.

Disclosure of Invention

According to the invention, the strontium content in the diet is increased by selecting crops in strontium-rich areas, the content of sodium element in the body is reduced, the strontium-sodium ratio is recovered, the cancer cells are promoted to become normal cells by adjusting body fluid, and the potato crops in the Yinghe river basin are rich in strontium element and can be used for producing foods for preventing and treating cancers. The sweet potato vermicelli is prepared by selecting sweet potatoes in Songshan Yinghe area.

Preferably, beneficial bacterium groups are added into the sweet potato vermicelli, and the beneficial bacterium groups generally refer to bacteria or fungi which grow in intestines and stomach of a human body and play a positive role in human health.

Preferably, the selenium-rich iron stick Chinese yam produced by the scorched selenium-rich soil is added into the sweet potato vermicelli to prepare the sweet potato vermicelli rich in strontium and selenium, and only the scorched selenium can produce the selenium-rich iron stick Chinese yam with medicinal value due to the unique selenium-rich soil of the scorched selenium.

The product is a food with homology of medicine and food, has small toxic and side effects, can be taken by patients for a long time, is convenient to carry and easy to store, and has wide application prospect.

The preparation method of the food comprises the following steps:

a, selecting materials: the vermicelli preparation can be made by weighing high-quality potato crop starch, mixing with water in proportion, breaking the wall, stirring, fermenting, and stirring into slurry in a slurry mixer;

b, adding seasonings;

and c, feeding the slurry into a high-temperature fast steaming section in the steaming box under the operation of the conveyer belt, and quickly shaping and then feeding into a slow steaming section for shaping.

And d, adding beneficial bacterium groups.

And e, finally putting the mixture into a freeze dryer for freeze drying treatment.

b, adding seasonings;

and c, feeding the slurry into a high-temperature fast steaming section in the steaming box under the operation of the conveyer belt, and quickly shaping and then feeding into a slow steaming section for shaping.

And d, finally, putting the mixture into a freeze dryer for freeze drying treatment, and packaging to obtain the product.

Strontium is an indispensable trace element for the human body, but is not known, let alone understood. If the human body lacks strontium, various symptoms which are not good for the health can appear, so that all tissues of the human body contain strontium. First, it is a normal component of human skeleton and teeth, and functions of the human body are closely related to the formation of skeleton. Secondly, it is also related to the function and structure of blood vessels, and strontium can help human body reduce sodium absorption and increase sodium excretion. Excessive sodium exists in vivo, and is easy to cause hypertension and cardiovascular diseases, and strontium has a prevention effect. Again, because some isotopes of strontium are radioactive, strontium also plays an important role in the treatment of pain. Strontium is taken in by human body mainly through food and drinking water, and is absorbed by digestive tract and then discharged out of body through urine. The absorption mechanism of strontium in small intestine has two absorption modes of active transportation and passive diffusion. Strontium is absorbed through the gastrointestinal tract, and also enters the human body through the respiratory tract and the skin. The strontium level in drinking water of China is very low, many mineral waters contain abundant strontium, and the natural drinking mineral water is obtained when the strontium content is 0.20-0.40 mg/L. In addition, the strontium level in the leaf vegetables is high, and the content of livestock, poultry, meat and eggs is low. Due to different eating habits, the strontium intake of part of people can be insufficient, and the strontium intake with sufficient quantity can be achieved by changing the eating habits. The strontium-containing mineral water with concentration of less than 5mg/L is beneficial to human health, and does not produce adverse effects. Metabolic processes of strontium 99.0% of strontium is present in bone in vivo and only 0.7% can be dissolved in extracellular fluid. The bone strontium and the blood strontium are continuously exchanged to ensure that the bone strontium and the blood strontium are in dynamic balance. High strontium and high calcium in the body are beneficial to the organism, and if high strontium and low calcium exist in the body, adverse effects are generated on the physiological metabolism of the organism, and even various pathological changes are generated. Strontium is excreted primarily by urine and the kidneys excrete strontium at a greater rate than calcium because the tubules reabsorb calcium faster than strontium. In the infant stage, the absorption function of renal tubules is not well developed, so that the strontium excretion capability of infants is weaker than that of adults. Specific effect of strontium on bone studies on the effect of strontium on mesenchymal stem cells indicate that strontium can regulate differentiation of MSCs (mesenchymal stem cells) into osteoblasts and promote synthesis and precipitation of bone matrix proteins. Therefore, strontium has an osteoblast differentiation and osteogenesis promoting effect. Effects of strontium on osteoblasts and osteoclasts the coordinated interaction between osteoblasts and osteoclasts is key to regulating bone remodeling and maintaining the stability and integrity of the skeleton. Strontium has been found to increase proliferation of preosteoblasts and pluripotent stem cells using at least two mechanisms. In addition, in animal models of osteoporosis, strontium can improve bone metabolism, prevent bone loss, and improve bone quality in osteoporotic animals. The influence of strontium on the bone strength is that in bones, strontium can replace a small amount of calcium in calcified tissue bones and hydroxyapatite crystals of teeth, the mechanical property of bones can be improved by properly doping strontium element, the improvement on the hardness is more obvious, probably because of the replacement of a small amount of strontium element, the lattice defect is reduced to a certain extent, the arrangement among atoms is more compact, and a certain strengthening effect is achieved, thereby improving the mechanical strength of bones. Studies of strontium with cardiovascular disease  show that the lower the level of strontium in drinking water, the higher the cardiovascular disease mortality. When the strontium in the drinking water is 5.0-10.0mg/L, the mortality rate of cardiovascular diseases is the lowest. The strontium level in drinking water and urine is obviously negatively correlated with hypertensive heart disease, the sodium/strontium ratio in drinking water is obviously positively correlated with central nervous system vascular injury, arteriosclerosis, degenerative heart disease and hypertensive heart disease, and the urine sodium/strontium ratio is obviously negatively correlated with systemic arteriosclerosis. The mechanism of action may be that strontium is competitively absorbed in the intestine with sodium, thereby reducing sodium absorption and increasing sodium excretion in the body. Excessive sodium in human body is easy to cause hypertension and cardiovascular diseases, while strontium can reduce the absorption of sodium in human body, so that it has the effect of preventing cardiovascular diseases. Strontium deficiency  hazard to humans the metabolism of strontium in humans is very similar to that of calcium. Organs rich in calcium also have more strontium, so bones and teeth are the primary reservoirs of strontium. The normal concentration of strontium in bones is 360ppm, and strontium is an essential element for normal calcification of bones and teeth. In the absence of strontium, the proportion relationship between strontium and calcium, barium and zinc is destroyed, and dental bone ulcer is caused. In addition, recent research data suggest: once a human body is lack of strontium, metabolic disorder in the body can be caused, and serious consequences such as limb weakness, sweating due to debility, slow development of bones and osteoporosis can be caused. When the strontium deficiency is the most serious, the people can suffer from tumors. Strontium 90-radioactive element the strontium element of the double-edged sword nature is not radioactive, but strontium-90 is radioactive with a half-life of 28.8 years. Strontium-90 is not a product of nature, its occurrence is a result of human activity, and nuclear fission is the most prominent source of strontium-90 production. After a nuclear leakage accident occurs in the first nuclear power station in fukushima, strontium-90, which is a radioactive substance, is detected in the atmosphere of 10 areas except for fukushima and the city of the uterus, including the areas of tokyo, arrowhead and the like. However, most of Japanese experts consider that the radiation dose has no influence on human health at present. The half-life of strontium-90 is about 30 years long, and the strontium-90 is easy to accumulate in human bones, so that the risk of bone cancer or leukemia is increased. The excessive strontium-90 has great harm to the health of human body, but the strontium-90 with controlled dosage can be used for treating hemangioma and other hemangioma diseases.

The invention discovers that the electronegativity of sodium is 0.93, potassium is 0.82, strontium is 0.95, the electronegativity of strontium element is closer to that of sodium, and laboratory researches show that strontium is superior to potassium in the aspect of improving the sodium content of a human body, strontium is added in a culture solution, and cancer cells can become normal cells.

Strontium competes with sodium at the absorption site of the human body, thereby reducing the absorption of sodium by the human body and increasing the excretion of sodium. Excessive sodium in the body is easy to cause hypertension and cardiovascular and cerebrovascular diseases, while strontium can reduce the absorption of sodium by the human body, so the strontium also has the effect of preventing diseases. Particularly for preventing the risk of residual circulating tumor cells (circulating tumor cells) in vivo from adhering to, migrating and invading peripheral tissues after surgery in cancer patients, resulting in tumor re-metastasis. Compared with the traditional anticancer drugs, the drug has small toxic and side effects, can be taken by patients for a long time, and has wide application prospect.

The research result shows that the strontium content of cancer patients is obviously lower than that of healthy people, wherein the cancer patients comprise 4 persons with lung cancer, 4 persons with liver cancer, 8 persons with stomach cancer, 4 persons with rectal cancer, 2 persons with breast cancer and 22 persons in total.

The tea pavilion sweet potatoes of the agricultural product geographical sign product have a long cultivation history in the region covered by the seal. The Yuan-Songshan-south foot at the Fucheng town, which belongs to a mountain area, is very suitable for planting sweet potatoes. The sweet potato tea pavilion has the characteristics of large size and good flavor, has the effects of strengthening the spleen and stomach, tonifying the liver and the kidney, preventing cancer, prolonging the life and beautifying after being frequently eaten, can supplement nutrition supply required by a human body after being eaten, can prevent the occurrence of the cancer after being used for a long time, becomes an important traditional Chinese medicinal material, and finds that the drug effect of the sweet potato tea pavilion is from Songshan Yinghe through investigation and detection of soil by the inventor, and the Songshan Yinghe which is originated from Songshan brings strontium element to the tea pavilion ditch, so that the tea pavilion sweet potato generates the cancer prevention drug effect. The sweet potato crops and the extract in the Yinghe river basin, particularly the Songshan-Yinghe river basin can be used as the medicine-food homologous food for preventing cancers, and provide scientific basis for developing and utilizing natural plant resources.

The selenium is called as 'anticancer king' in human body trace elements by scientists, and the research of the scientific community finds that the level of the blood selenium is closely related to the occurrence of cancer. Selenium has effects of enhancing immunity, removing toxic substance, resisting toxicity, resisting radiation, resisting aging, protecting and improving vision, protecting cardiovascular and cerebrovascular, preventing thyroid diseases, and inhibiting tumor. Research shows that selenium deficiency is closely related to cardiovascular and cerebrovascular diseases such as coronary heart disease, arteriosclerosis, hypertension and the like, liver cancer, diabetes and the like. A great deal of research data indicates that the selenium content in food and soil in a region is directly related to the incidence of cancer, such as: the selenium content in the food and soil in the area is high, the incidence rate and the mortality rate of the cancer are low, and conversely, the incidence rate and the mortality rate of the cancer in the area are high, and the fact shows that the selenium is closely related to the occurrence of the cancer. Meanwhile, the scientific community also recognizes that selenium is the 'king of cancer resistance' in the trace elements of the human body. The organic selenium can eliminate free radicals in vivo, eliminate toxin in vivo, resist oxidation, effectively inhibit the generation of lipid peroxide, prevent blood clot, eliminate cholesterol, and enhance immunity. Selenium is an active ingredient constituting glutathione peroxidase, and it can prevent oxidative destruction of islet beta cells, normalize its function, promote sugar metabolism, reduce blood sugar and urine sugar, and improve symptoms of diabetic patients. Selenium can protect retina, enhance vitreous smoothness, improve vision, and prevent cataract. Selenium is an important element for maintaining the normal function of the heart and has the functions of protecting and repairing the heart muscle. The reduction of the blood selenium level of a human body can cause the function of eliminating free radicals in the body to be reduced, so that the deposition of harmful substances is increased, the blood pressure is increased, the vascular wall is thickened, the elasticity of blood vessels is reduced, the blood flow speed is slowed, and the oxygen supply function is reduced, thereby inducing the incidence rate of cardiovascular and cerebrovascular diseases to be increased, however, the scientific selenium supplement has better effects on preventing cardiovascular and cerebrovascular diseases, hypertension, arteriosclerosis and the like. Selenium deficiency is the main cause of keshan disease, Kashin-Beck disease and two endemic diseases, and selenium supplement can prevent marrow end lesion, promote repair and promote disulfide bond to resist metal element detoxification in protein synthesis. Has good prevention and treatment effects on the two endemic diseases and arthritis patients. The selenium has strong binding force with metal, and can resist the poison of cadmium to kidney, gonad and central nerve. Selenium is combined with mercury, tin, thallium, lead and other heavy metals in the body to form metal selenium protein for compounding, detoxifying and expelling toxin. The epidemiological investigation of Chinese medical experts on the liver cancer high-incidence area discovers that the selenium content in the blood of residents in the liver cancer high-incidence area is lower than that in the liver cancer low-incidence area, the incidence rate of liver cancer is negatively related to the blood selenium level, the incidence rate of liver cancer is reduced by supplementing selenium, and the incidence rate of patients with liver cancer family history is reduced.

Sweet potatoes are particularly rich in lysine, while rice and flour are just lack of lysine. Lysine can inhibit the uptake of nutrients by cancer cells, thereby inhibiting the proliferation of cancer cells. The traditional Chinese medicine considers that: sweet potato also has effects of clearing intestine and stomach and removing toxic substance. Said Qianlong emperor likes to eat sweet potato, so that it can solve the problem of senile constipation. Indeed, sweet potatoes contain a large amount of dietary fibers, and can stimulate gastrointestinal motility and prevent constipation. Meanwhile, the retention time of the excrement in the intestinal tract is reduced, the contact between carcinogenic substances and intestinal mucosa can be reduced, the discharge of toxins in the intestinal tract is facilitated, and the generation of carcinogenic substances is reduced.

Research shows that the sweet potato is not only a delicious dish on a dining table, but also an anticancer food. In 1982, American biologists found that sweet potato contains an active substance called Dehydroepiandrosterone (DHEA), which is a steroid similar to adrenal gland neohormone in mammals, and injected into mice inoculated with cancer cells, the active substance can prevent the mice from suffering from colon cancer and breast cancer, and prolong the life span of the mice.

Analysis of more than 40 vegetable anticancer components and experimental cancer inhibition tests by the national cancer prevention research institute of Japan show that cooked and raw sweet potatoes are respectively named as 'Guanyajun' in vegetables with obvious tumor inhibition effect.

Japanese scientists have also found that four-fold concentration of sweet potato juice inhibits cancer cell proliferation by a factor of five more than ordinary sweet potato juice. They also extracted that residues after the starch is made from sweet potatoes contain substances for inhibiting cancer cell proliferation, and the sweet potatoes eaten by people daily also contain the substances for inhibiting cancer.

The nutrient of the dioscorea opposita has the function of inducing the production of interferon and enhancing the cellular immune function of human bodies. The liver alkaloid and lecithin contained in rhizoma Dioscoreae are helpful for improving memory function of human. The glycoprotein can prevent fat deposition of cardiovascular system, maintain blood vessel elasticity, prevent atherosclerosis and reduce subcutaneous fat deposition, the dopamine can effectively expand blood vessels and improve blood circulation, the saponin can prevent coronary heart disease and fatty liver, the pectin can increase activity of T lymphocyte, improve phagocytic ability of reticuloendothelial system, enhance immunity of organism and inhibit tumor cell reproduction. Therefore, yam can be used as an auxiliary drug for resisting tumors, radiotherapy, chemotherapy and post-operation body-shirts and is listed in the anticancer Chinese herbal medicine dictionary.

By analyzing the selenium content in the potato crops in different producing areas in a laboratory, the selenium content of the potato crops produced in the selenium-rich soil area is far higher than that of the potato crops produced in the non-selenium-rich area.

Has the advantages that:

the invention has the advantages that: by increasing the strontium content in food, strontium ions replace sodium ions in a body, the selenium content in the body is increased at the same time, and a sodium selenide compound is generated by combining selenium element and sodium element, so that the sodium content in the body is reduced from two aspects, the disease control and improvement effects on tumor patients and cancer patients are improved, and the development of colon cancer and breast cancer can be prevented by combining an active substance of Dehydroepiandrosterone (DHEA); the invention can extract the nutrient substances in the cell nucleus to the maximum extent by multiple wall-breaking technologies, can ensure that the nutrient components are not lost to the maximum extent by a freeze-drying technology, and has the advantages of wide adaptation diseases, exact curative effect, convenient oral administration and external use, safety, reliability and no toxicity.

Although the invention has been described in detail hereinabove with respect to a general description and specific embodiments thereof, it will be apparent to those skilled in the art that modifications or improvements may be made thereto based on the invention. Therefore, it is within the scope of the present invention to make such modifications or improvements without departing from the spirit of the present invention to select other strontium-rich potato crops and the like, and to add other common nutritional ingredients.