阅读说明：本技术 能够与炎性和代谢性疾病的生物标志物结合的新型肽及其用途 (Novel peptides capable of binding to biomarkers of inflammatory and metabolic diseases and uses thereof ) 是由 朴玧贞 郑钟平 李周娟 于 2019-08-29 设计创作，主要内容包括：本发明涉及：肽,其具有ATF3结合能力并由选自SEQ ID NOS:1至4的任一氨基酸序列表示；融合肽,其中细胞通透性肽与具有ATF3结合能力的肽键合；以及所述肽用于治疗炎性疾病、代谢性疾病、自身免疫性疾病和/或纤维化疾病的用途。根据本发明,提供了具有ATF3结合能力的新型肽,从而调节ATF3的细胞内浓度,并且因此可用于治疗炎性疾病、代谢性疾病、自身免疫性疾病和/或纤维化疾病,所述ATF3为在各种炎性疾病、代谢性疾病、自身免疫性疾病和/或纤维化疾病的发生中用作生物标志物和重要因子的蛋白质。此外,通过进一步将具有细胞内渗透性和炎症抑制性功能的肽与所述肽融合,可以增强疾病治疗效果。(The present invention relates to: a peptide having ATF3 binding ability and represented by any one amino acid sequence selected from the group consisting of SEQ ID NOS:1 to 4; a fusion peptide in which a cell-permeable peptide is bonded to a peptide having ATF 3-binding ability; and the use of said peptides for the treatment of inflammatory, metabolic, autoimmune and/or fibrotic diseases. According to the present invention, there is provided a novel peptide having ATF3 binding ability, thereby modulating the intracellular concentration of ATF3, and thus being useful for treating inflammatory diseases, metabolic diseases, autoimmune diseases, and/or fibrotic diseases, the ATF3 being a protein used as a biomarker and an important factor in the occurrence of various inflammatory diseases, metabolic diseases, autoimmune diseases, and/or fibrotic diseases. In addition, by further fusing a peptide having intracellular permeability and inflammation inhibitory functions to the peptide, the disease treatment effect can be enhanced.)