阅读说明：本技术 一氧化氮释放第5型磷酸二酯酶抑制剂 (Nitric oxide releasing phosphodiesterase type 5 inhibitors ) 是由 N·阿尔米兰特 S·布兰比拉 L·斯托洛尼 F·因派纳提洛 E·巴斯蒂亚 于 2019-07-31 设计创作，主要内容包括：本发明涉及式(I)或(Ib)或(II)的一氧化氮释放第5型磷酸二酯酶(PDE5)抑制剂或其立体异构体或药学上可接受的盐,其可用于治疗与眼内压升高相关的眼病症诸如高眼压、青光眼或视网膜病变。本发明进一步涉及3-[(2S)-2,3-双(硝氧基)丙氧基]丙酸和6-(硝氧基)己酸,其用于治疗与眼内压升高相关的眼病症诸如高眼压、青光眼或视网膜病变。(The present invention relates to nitric oxide releasing phosphodiesterase type 5 (PDE5) inhibitors of formula (I) or (Ib) or (II) or a stereoisomer or pharmaceutically acceptable salt thereof, which are useful for the treatment of ocular disorders associated with elevated intraocular pressure such as ocular hypertension, glaucoma or retinopathy. The invention further relates to 3- [ (2S) -2, 3-bis (nitrooxy) propoxy]Propionic acid and 6- (nitrooxy) hexanoic acid for use in the treatment of ocular disorders associated with elevated intraocular pressure such as ocular hypertension, glaucoma or retinopathy.)