阅读说明：本技术 血样分析仪、血样分析方法及计算机存储介质 (Blood sample analyzer, blood sample analyzing method, and computer storage medium ) 是由 谢子贤 胡力坚 于 2018-08-24 设计创作，主要内容包括：本申请公开了一种血样分析仪,包括：运样装置,用于运送装有样本容器的样本架；第一混匀装置,具有用于搅拌所述样本容器中的血液样本的样本搅拌部件,所述第一混匀装置能够驱动所述样本搅拌部件对所述样本容器的血液样本进行混匀；第二混匀装置,能够获取所述样本架或所述样本架上的所述第二样本容器,并能够驱动所述第二混匀位上的装有常量血液样本的第二样本容器以进行血液样本的混匀；控制装置,与所述运样装置、所述第一混匀装置和所述第二混匀装置通信连接,控制所述运样装置、所述第一混匀装置和所述第二混匀装置的动作。此外,本申请还公开了一种血样混匀装置、血样分析方法、以及一种计算机存储介质。(The application discloses blood sample analyzer includes: the sample conveying device is used for conveying the sample rack filled with the sample container; a first mixing device having a sample stirring member for stirring the blood sample in the sample container, the first mixing device being capable of driving the sample stirring member to mix the blood sample in the sample container; the second blending device can obtain the sample rack or the second sample container on the sample rack and can drive the second sample container filled with the constant blood sample on the second blending position to blend the blood sample; and the control device is in communication connection with the sample transporting device, the first blending device and the second blending device and controls the actions of the sample transporting device, the first blending device and the second blending device. In addition, the application also discloses a blood sample mixing device, a blood sample analysis method and a computer storage medium.)

A blood sample analyzer, comprising:

a sample transport device for transporting a sample rack containing first and/or second sample containers;

the first blending device is provided with a sample stirring component for stirring the blood sample in the first sample container, and the first blending device can drive the sample stirring component to blend the blood sample in the first sample container filled with trace blood sample on the sample rack at a first blending position;

the second blending device can obtain the sample rack or the second sample container on the sample rack and can drive the second sample container filled with the constant blood sample on the second blending position to blend the blood sample;

and the control device is in communication connection with the sample transporting device, the first blending device and the second blending device and controls the actions of the sample transporting device, the first blending device and the second blending device.

The blood sample analyzer of claim 1, wherein: the sample conveying device can convey the sample rack provided with the first and/or second sample containers to the first mixing position; the second blending device can obtain the sample rack from the first blending position or convey the second sample container on the sample rack to the second blending position.

The blood sample analyzer of claim 1, wherein: the first blending position and the second blending position are at the same position.

The blood sample analyzer of claim 1, wherein: the head of the sample stirring part is cylindrical, paddle-shaped or polygonal.

The blood sample analyzer of claim 1, wherein: the control device controls the sample stirring component to stir in one or a combination of a plurality of modes of autorotation, a circumferential orbit, linear oscillation or up-down oscillation.

The blood sample analyzer of claim 1, wherein: the sample stirring component can move up and down and can move down to a first sample container on the first blending position to stir and blend.

The blood sample analyzer of claim 1, further comprising:

the cleaning component is used for cleaning the sample stirring component; preferably, the cleaning part comprises a cleaning liquid inlet and a cleaning liquid outlet to perform a cleaning operation on the sample stirring part located in the cleaning part; more preferably, the cleaning solution discharge port may be further used for performing air suction to dry the sample stirring member.

The blood sample analyzer of claim 1, further comprising:

a washing part including a washing tank capable of washing the sample agitating part.

The blood sample analyzer of claims 1-8, further comprising:

the sample bin assembly comprises a sample bin cover and a sample container fixing hole, and is used for single sample injection of micro blood samples or macro blood samples placed on the sample container fixing hole.

The blood sample analyzer of claim 9 further comprising:

the control device is also used for judging whether the current sample injection mode is a first sample injection mode or a second sample injection mode;

when the first sample introduction mode is judged, controlling the sample conveying device to convey the sample rack provided with the first and/or second sample containers;

and when the second sample feeding mode is judged, controlling the sample cabin component to convey a single first sample container and/or a single second sample container.

The blood sample analyzer of claim 1, wherein: the sample conveying device conveys the sample rack provided with the first sample container to a preset position, and the clamping jaw of the second blending device can grab the first sample container from the sample rack at the preset position to the first blending position.

The blood sample analyzer according to any one of claims 1 to 11, further comprising:

measurement mode setting means for setting a first measurement mode and a second measurement mode;

wherein the control device executes the following actions according to the setting of the measurement mode setting device:

(1) determining whether the first measurement mode or the second measurement mode;

(2) when the first measurement mode is judged, controlling the first blending device to blend the blood sample in the first sample container;

(3) and when the second measurement mode is judged, controlling the second blending device to grab the second sample container for blending.

The blood sample analyzer of claim 12, further comprising:

the sample sucking device is used for sucking the uniformly mixed blood sample from the sample container;

when the first measurement mode is determined, the control device controls the sample aspirating device to aspirate a first blood sample volume from the first sample container;

when the second measurement mode is determined, the control device controls the sample suction device to suck a second blood sample volume from the second sample container;

wherein the first sample amount is less than the second sample amount; preferably said first sample volume is between 5 and 50 μ L, more preferably between 15 and 35 μ L.

The blood sample analyzer of claim 12, wherein:

the measurement mode setting device is also used for setting a third measurement mode;

and when the control device judges that the measurement mode is the third measurement mode, the control device controls the first blending device to blend the pre-diluted blood sample in the first sample container.

The blood sample analyzer as set forth in any one of claims 1 to 14, wherein: the first blending device is used for blending the blood sample in the first sample container, and the blood sample in the first sample container is a whole blood sample; preferably, the blood sample of the first sample container is 30-250. mu.L, more preferably 50-200. mu.L, still more preferably 50-100. mu.L.

The blood sample analyzer as set forth in any one of claims 1 to 15, wherein: after the first blending device is used for blending the trace blood sample in the first sample container, the fluctuation range of the hemoglobin value of the trace blood sample is repeatedly measured for many times and is not more than +/-2 g/L.

A blood sample analyzer, comprising:

the sample bin assembly is provided with a sample bin cover and a sample container fixing hole and is used for single sample injection of a micro blood sample or a macro blood sample placed on the sample container fixing hole;

and the blending device is provided with a sample stirring component for stirring the blood sample in the sample container, and can drive the sample stirring component to blend the blood sample in the sample container.

The blood sample analyzer of claim 17, wherein: the blood sample analyzer is used only for processing micro whole blood samples and pre-diluted blood samples.

The blood sample analyzer of claim 17, further comprising:

the sample suction device is used for sucking the uniformly mixed blood sample from the sample container;

a sample preparation device for preparing the blood sample aspirated by the sample aspiration device into a sample for detection;

and the control device is in communication connection with the blending device, the sample sucking device and/or the sample preparing device and controls the actions of the blending device, the sample sucking device and/or the sample preparing device.

The blood sample analyzer of claim 19 further comprising:

measurement mode setting means for setting a first measurement mode and a second measurement mode;

wherein the control device executes the following actions according to the setting of the measurement mode setting device:

(1) determining whether the first measurement mode or the second measurement mode;

(2) when the measurement mode is the first measurement mode, controlling the sample aspirating device to aspirate a first sampling amount of the blood sample from the sample container on the sample rack, and controlling the sample preparing device to prepare a first test sample;

(3) when the second measurement mode is determined, controlling the sample aspirating device to aspirate a second sampling amount of the blood sample from the sample container on the sample rack, and controlling the sample preparing device to prepare a second test sample;

wherein the first sample amount is less than the second sample amount; preferably said first sample volume is between 5 and 50 μ L, more preferably between 15 and 35 μ L.

The blood sample analyzer of claim 20, wherein:

the measurement mode setting device is also used for setting a third measurement mode;

and when the control device judges that the measurement mode is the third measurement mode, the sample suction device is controlled to suck a third sampling amount of pre-diluted blood sample from the sample container on the sample rack, and the sample preparation device is controlled to prepare a third detection sample.

A blood sample analyzer, comprising:

the first blending device can blend the blood sample in the first sample container;

a second mixing device capable of mixing the blood sample in the second sample container differently from the first mixing device;

the control device is in communication connection with the first blending device and the second blending device and can execute the following operations:

(1) judging whether the measurement mode is a first measurement mode or a second measurement mode;

(2) when the first measurement mode is judged, controlling the first blending device to blend the blood sample in the first sample container;

(3) and when the second measurement mode is judged, controlling the second blending device to blend the blood sample in the second sample container.

The blood sample analyzer of claim 22 wherein the control device is further operable to:

(1) judging whether the measurement mode is the third measurement mode;

(2) and when the control device judges that the measurement mode is the third measurement mode, the control device controls the first blending device to blend the pre-diluted blood sample in the sample container.

The blood sample analyzer of claim 22, wherein the blood sample in the first sample container is a whole blood sample, preferably the volume of the blood sample in the first sample container is 30-250 μ l, more preferably 50-200 μ l, and even more preferably 50-100 μ l.

The blood sample analyzer of any one of claims 22-24 further comprising:

a sample chamber assembly having a sample chamber cover and a sample container fixing hole for single sample injection of a blood sample placed on the sample container fixing hole; and/or

And the sample conveying device is used for conveying the sample rack filled with the first sample container and/or the second sample container.

The blood sample analyzer of claim 25 wherein the control device is further operable to:

(1) judging whether the sample is in a first sample injection mode or a second sample injection mode;

(2) when the first sample introduction mode is judged, controlling the sample conveying device to convey the sample rack provided with the sample container;

(3) and when the second sample introduction mode is judged, controlling the sample bin assembly to convey a single sample container to the blood analyzer.

A blood sample analyzer, comprising:

the sample conveying device is used for conveying the sample rack filled with the sample container;

a mixing device having a sample stirring member for stirring the blood sample in the sample container, the mixing device being capable of driving the sample stirring member to mix the blood sample in the sample container;

and the control device is in communication connection with the sample transporting device and the blending device and controls the actions of the sample transporting device and the blending device.

A method for blood sample analysis for blood routine comprising:

transporting the sample container with the blood sample to a mixing location;

driving a sample stirring part of a first blending device to blend the blood sample in the sample container;

aspirating a predetermined sampling amount of the blood sample from the sample container at the mixing position to prepare a test sample for a blood routine test item;

and detecting the detection sample to obtain the relevant indexes of the routine blood detection items.

The method of analyzing a blood sample of claim 28, further comprising:

judging whether the current measurement mode is a first measurement mode or a second measurement mode;

if the first measurement mode is determined, aspirating a first sample amount of the homogenized blood sample from the first sample container, and preparing a first detection sample;

when the second measurement mode is judged, aspirating a second sampling amount of the uniformly mixed blood sample from a second sample container, and preparing a second test sample;

wherein the first sample amount is less than the second sample amount; preferably said first sample volume is between 5 and 50 μ L, more preferably between 15 and 35 μ L.

The method of analyzing a blood sample of claim 29, further comprising:

judging whether the current measurement mode is a third measurement mode;

if the measurement mode is the third measurement mode, the mixed pre-diluted blood sample of the third sampling amount is aspirated from the first sample container, and a third test sample is prepared.

The method of analyzing a blood sample according to any one of claims 28 to 30, further comprising:

judging whether the current sample injection mode is a first sample injection mode or a second sample injection mode;

when the first sample introduction mode is judged, the sample container is conveyed by the sample conveying device;

and when the second sample introduction mode is judged, conveying the single sample container to the blood analyzer by the sample cabin assembly.

The method for analyzing a blood sample according to any one of claims 28 to 30, wherein: the sample stirring component is used for stirring in one or a combination of a plurality of modes of autorotation, circular orbit, linear oscillation or up-down oscillation.

The method of analyzing a blood sample according to any one of claims 28 to 30, further comprising: the second blending device obtains a second sample container for reverse blending.

The method for analyzing a blood sample according to any one of claims 28 to 30, wherein: the amount of the blood sample in the first sample container is less than or equal to 250 mu L; preferably, the amount of the blood sample in the first sample container is 30-250 μ L, more preferably, the amount of the blood sample in the first sample container is 50-200 μ L, and more preferably, the amount of the blood sample in the first sample container is 50-100 μ L.

A method of analyzing a blood sample, comprising:

a measurement mode determination step: judging whether the current measurement mode is a first measurement mode or a second measurement mode;

first detection sample preparation step: when the first measurement mode is judged, controlling a first blending device to drive a sample stirring part to blend the blood sample in the sample container, and sucking the blood sample with a first sampling amount to prepare a first detection sample;

a second detection sample preparation step: when the second measurement mode is judged, controlling a second blending device to blend the blood sample in the sample container, and sucking a second sampling amount of the blood sample to prepare a second detection sample; and

a detection step: detecting the first detection sample or the second detection sample.

The method of analyzing a blood sample of claim 35, wherein:

in the measurement mode determining step, whether the current measurement mode is a third measurement mode is also judged;

a third detection sample preparation step: when the first mixing device is judged to be in the third measurement mode, the first mixing device is controlled to mix the pre-diluted blood sample in the sample container uniformly, and the pre-diluted blood sample with a third sampling amount is aspirated to prepare a third test sample;

in the detecting step, the third detection sample is detected.

The method of analyzing a blood sample of claim 35 or 36, further comprising:

a sample injection mode determining step: judging whether the current sample injection mode is a first sample injection mode or a second sample injection mode;

a sample frame conveying step: when the sample is judged to be in the first sample introduction mode, controlling a sample conveying device to convey the sample rack provided with the sample container to a preset position, and conveying the uniformly mixed sample container to a first sampling position;

closing the sample bin assembly: and when the second sampling mode is judged, closing the sample bin assembly, and sending the sample container to a second sampling position.

The method for analyzing blood samples according to claim 35 or 36, wherein:

in the first detection sample preparation step, the second mixing device conveys the sample container on the sample rack conveyed to the preset position by the sample conveying device to the first mixing position for mixing;

in the second test sample preparation step, the sample rack transported to the predetermined position by the sample transport device or the sample container on the sample rack is grasped by the second kneading device and kneaded upside down.

A method for analyzing a blood sample according to any one of claims 35 to 37, wherein: the blood sample in the sample container uniformly mixed by the first uniformly mixing device is a whole blood sample, the amount of the blood sample is 30-250 mu L, more preferably, the amount of the blood sample is 50-200 mu L, and more preferably, the amount of the blood sample is 50-100 mu L.

A blood sample analyzer, comprising:

the sample conveying device is used for conveying the sample rack filled with the sample container;

the blending device is provided with a sample sucking device for sucking and spitting a blood sample in a sample container, and the sample sucking device can drive the sample sucking of the sample sucking device to suck, spit and blend the blood sample in the sample container with a trace amount of whole blood sample on a sampling position;

and the control device is in communication connection with the sample transporting device and the blending device and controls the actions of the sample transporting device and the blending device.

The blood sample analyzer of claim 40 wherein: the sample sucking device further comprises a sucking and spitting driving device which is used for driving the sample sucking needle to suck and spit the blood sample in the sample container for mixing, and preferably the sucking and spitting driving device is an injector.

The blood sample analyzer of claim 41 wherein: the suction and spitting driving device can drive the sample suction needle to suck a proper amount of air before uniformly mixing the blood sample in the sample container, so that a section of isolation air column is formed inside the sample suction needle.

The blood sample analyzer of claim 40 wherein: the device also comprises a second blending device which can obtain the sample container with the constant blood sample on the sample rack and carry out reverse blending.

The blood sample analyzer of claim 40 wherein: the sample suction device also comprises a sample suction needle air drying device which is used for air drying the outer wall of the sample suction needle.

A blood sample analyser as claimed in any one of claims 40 to 44 wherein: the sample suction device also comprises a sample suction needle position sensor which is used for sensing the descending position of the sample suction needle.

A blood sample analyser as claimed in any one of claims 40 to 44 wherein: the amount of the trace whole blood sample is 30-250 mu L, preferably 50-200 mu L, and more preferably 50-100 mu L.

A method of blending a blood sample, comprising:

a sample sucking needle sucks a proper amount of air to form a section of isolation air column inside the sample sucking needle;

driving the sample sucking needle to descend to be close to the bottom of the sample container;

after the sample sucking needle is driven to suck a proper amount of whole blood sample, the sucked blood sample is returned to the sample container, so that the blood sample in the sample container forms a certain flow until the blood sample is uniformly mixed.

The method of claim 47, further comprising:

judging whether the sample injection mode is a first sample injection mode or a second sample injection mode;

if the first sample feeding mode is adopted, the sample container on the sample rack is conveyed to a first sampling position by a sample conveying device; if the second sampling mode, the single sample container is transported by the sample bin assembly to a second sampling site.

A control device for a blood sample analyzer, comprising:

at least one processor; and

a memory storing instructions executable by the at least one processor, the instructions, when executed by the at least one processor, cause the blood sample analyzer to perform the method of any one of claims 27-38, 46-47.

A computer storage medium storing computer-executable instructions that, when executed by at least one processor of a blood sample analyzer, cause the blood sample analyzer to perform the method of any one of claims 28-39, 47-48.