阅读说明：本技术 一种人参小分子肽压片糖果及提纯制备工艺 (Ginseng small-molecule peptide tablet candy and purification preparation process ) 是由 李宗刚 于 2019-09-18 设计创作，主要内容包括：本发明公开了一种人参小分子肽压片糖果及制备工艺,包括以下组分及重量份：人参肽20-25份、玛咖提取物5-9份、牡蛎干提取物4-5份、山药粉10-15份、山茱萸提取物5-9份、当归提取物8-11份、鹿鞭提取物7-9份、鹿肾提取物7-9份、黄芪提取物2-4份、枸杞子粉3-7份、黄精提取物3-7份、肉苁蓉提取物3-7份,所述山药粉、枸杞子粉的粒径在10μm至12μm之间。压片糖果直接采用人参肽作为主要成成分,其余成分绝大部分采用提取物,不仅便于有效物质的被人体吸收；各成分之间相互协同作用,还有利于提高压片糖果滋阴补阳的效果。(The invention discloses a ginseng small molecule peptide tablet candy and a preparation process thereof, wherein the ginseng small molecule peptide tablet candy comprises the following components in parts by weight: 20-25 parts of ginseng peptide, 5-9 parts of maca extract, 4-5 parts of dried oyster extract, 10-15 parts of yam powder, 5-9 parts of dogwood extract, 8-11 parts of angelica extract, 7-9 parts of penis cervi extract, 7-9 parts of deer kidney extract, 2-4 parts of astragalus extract, 3-7 parts of wolfberry powder, 3-7 parts of rhizoma polygonati extract and 3-7 parts of cistanche extract, wherein the particle sizes of the yam powder and the wolfberry powder are between 10 and 12 mu m. The tablet candy directly adopts the ginseng peptide as the main component, and the majority of the other components adopt the extract, so that the effective substances are conveniently absorbed by the human body; the ingredients have synergistic effect, and the tablet candy is beneficial to improving the effects of nourishing yin and tonifying yang.)

1. The ginseng small-molecule peptide tablet candy is characterized by comprising the following components in parts by weight: 20-25 parts of ginseng peptide, 5-9 parts of maca extract, 4-5 parts of dried oyster extract, 10-15 parts of yam powder, 5-9 parts of dogwood extract, 8-11 parts of angelica extract, 7-9 parts of penis cervi extract, 7-9 parts of deer kidney extract, 2-4 parts of astragalus extract, 3-7 parts of wolfberry powder, 3-7 parts of rhizoma polygonati extract and 3-7 parts of cistanche extract, wherein the particle sizes of the yam powder and the wolfberry powder are between 10 and 12 mu m.

2. The ginseng small-molecular-peptide tabletted candy as claimed in claim 1, wherein the ginseng peptide is 25 parts, the maca extract is 5 parts, the dried oyster extract is 4 parts, the yam powder is 10 parts, the dogwood extract is 5 parts, the angelica sinensis extract is 8 parts, the deer penis extract is 7 parts, the deer kidney extract is 7 parts, the astragalus extract is 2 parts, the wolfberry powder is 3 parts, the polygonatum extract is 3 parts, and the cistanche deserticola extract is 3 parts.

3. The ginseng small-molecular-peptide tabletted candy as claimed in claim 1, wherein the ginseng peptide is 20 parts, the maca extract is 9 parts, the dried oyster extract is 5 parts, the yam powder is 15 parts, the dogwood extract is 9 parts, the angelica sinensis extract is 11 parts, the deer penis extract is 9 parts, the deer kidney extract is 9 parts, the astragalus membranaceus extract is 4 parts, the wolfberry powder is 7 parts, the polygonatum sibiricum extract is 7 parts, and the cistanche deserticola extract is 7 parts.

4. The ginseng small-molecular-peptide tabletted candy as claimed in claim 1, wherein the ginseng peptide is 22 parts, the maca extract is 6 parts, the dried oyster extract is 4 parts, the yam powder is 12 parts, the dogwood extract is 7 parts, the angelica sinensis extract is 10 parts, the deer penis extract is 8 parts, the deer kidney extract is 8 parts, the astragalus membranaceus extract is 3 parts, the wolfberry powder is 5 parts, the polygonatum sibiricum extract is 5 parts, and the cistanche deserticola extract is 5 parts.

5. The ginseng small-molecule peptide tabletted candy as claimed in any one of claims 1 to 4, further comprising the following components in parts by weight: 4-5 parts of maltodextrin and 5-8 parts of food additives.

6. A purification preparation process of ginseng small molecule peptide tablet candy is characterized by comprising the following steps:

A. preparation of the extract: producing the extract of any one of claims 1 to 4 from raw materials;

B. preparation of powdery raw materials: grinding the dried yam and medlar powder to a particle size of between 10 and 12 mu m;

C. mixing and granulating: proportioning and mixing the components according to any one of claims 1 to 4, adding water for wetting and granulating;

D. drying, granulating and tabletting: drying at 40-55 deg.C, mixing with magnesium stearate and food additive, and tabletting.

7. The purification and preparation process of ginseng small-molecule peptide tabletted candy as claimed in claim 6, wherein the step A further comprises crushing the maca extract, the dried oyster extract, the dogwood extract, the angelica sinensis extract, the penis cervi extract, the astragalus membranaceus extract, the polygonatum sibiricum extract and the cistanche deserticola extract, and crushing the extracts to a particle size of less than 1 μm.

8. The purification and preparation process of ginseng small-molecule peptide tabletted candy as claimed in claim 6, wherein the oyster dry extract and the polygonatum sibiricum extract are both prepared by a water boiling extraction and concentration method.

9. The purification and preparation process of ginseng small-molecule peptide tabletted candy as claimed in claim 6, wherein the ginseng peptide is extracted by the following method:

pulverizing dried Ginseng radix, extracting with composite organic solvent at 35 deg.C under microwave for 25 min, and filtering to obtain filtrate;

extracting with swelling solvent;

performing compound enzymolysis;

two-phase extraction;

separating and purifying to obtain the ginseng peptide.

Technical Field

The invention relates to the field of tabletting candies, in particular to a ginseng small-molecule peptide tabletting candy and a purification preparation process.

Background

Ginseng (panaxginsengc.a.mey) is a perennial herb which is fond of shade and cool, leaves have no air holes and fence tissues and cannot retain water, leaves can be burnt when the temperature is higher than 32 ℃, and the degree of closure is 0.7-0.8. Usually, the flower blossoms in 3 years, the fruits come out in 5-6 years, the flowering period is 5-6 months, and the fruit period is 6-9 months; the hybrid forest is mainly a broad-leaved mixed forest or a deciduous broadleaf forest which grows at an altitude of hundreds of meters between 33 and 48 degrees north latitude and mainly comprises Korean pine. Ginseng, as an ancient nutritional tonic, has effects of refreshing brain, promoting blood circulation, relieving fatigue, and enhancing immunity. Modern medical research shows that ginseng also has the effects of reducing blood pressure, inhibiting diabetes, improving memory and the like, and has the advantages of no drug resistance, wide applicable population and the like. Based on the above advantages, ginseng is widely used, and how to improve the drug effect is a focus of attention.

Disclosure of Invention

The invention provides a ginseng small-molecule peptide tablet candy and a purification preparation process for solving the technical problems.

The invention is realized by the following technical scheme:

a ginseng small molecule peptide tablet candy comprises the following components in parts by weight: 20-25 parts of ginseng peptide, 5-9 parts of maca extract, 4-5 parts of dried oyster extract, 10-15 parts of yam powder, 5-9 parts of dogwood extract, 8-11 parts of angelica extract, 7-9 parts of penis cervi extract, 7-9 parts of deer kidney extract, 2-4 parts of astragalus extract, 3-7 parts of wolfberry powder, 3-7 parts of rhizoma polygonati extract and 3-7 parts of cistanche extract, wherein the particle sizes of the yam powder and the wolfberry powder are between 10 and 12 mu m. The ginseng peptide belongs to a cell level type, is a small molecular peptide extracted from ginseng, is rich in 18 amino acids, ginseng active ingredients, namely ginsenoside and trace elements, contains 8 essential amino acids in the 18 amino acids, and has the molecular weight of 180-1000 daltons. The small molecule peptide has simple structure and small molecular weight, so that the small molecule peptide can directly enter cells in an original shape through the permeation of cell membranes without being digested again and consuming energy. The tablet candy directly adopts the ginseng peptide as the main component, and the majority of the other components adopt the extract, so that the effective substances are conveniently absorbed by the human body; the ingredients have synergistic effect, and the tablet candy is beneficial to improving the effects of nourishing yin and tonifying yang.

Preferably, the ginseng peptide is 25 parts, the maca extract is 5 parts, the dried oyster extract is 4 parts, the yam powder is 10 parts, the dogwood extract is 5 parts, the angelica sinensis extract is 8 parts, the penis cervi extract is 7 parts, the astragalus membranaceus extract is 2 parts, the wolfberry powder is 3 parts, the rhizoma polygonati extract is 3 parts, and the cistanche deserticola extract is 3 parts.

Preferably, the ginseng peptide is 20 parts, the maca extract is 9 parts, the dried oyster extract is 5 parts, the yam powder is 15 parts, the dogwood extract is 9 parts, the angelica extract is 11 parts, the penis cervi extract is 9 parts, the astragalus extract is 4 parts, the wolfberry powder is 7 parts, the rhizoma polygonati extract is 7 parts, and the cistanche extract is 7 parts.

Preferably, the ginseng peptide is 22 parts, the maca extract is 6 parts, the dried oyster extract is 4 parts, the yam powder is 12 parts, the dogwood extract is 7 parts, the angelica sinensis extract is 10 parts, the penis cervi extract is 8 parts, the astragalus membranaceus extract is 3 parts, the wolfberry powder is 5 parts, the rhizoma polygonati extract is 5 parts, and the cistanche deserticola extract is 5 parts.

Further, the composition also comprises the following components in parts by weight: 4-5 parts of maltodextrin and 5-8 parts of food additives.

A purification preparation process of ginseng small molecule peptide tablet candy comprises the following steps:

A. preparation of the extract: producing the extract by using raw materials;

B. preparation of powdery raw materials: grinding the dried yam and medlar powder to a particle size of between 10 and 12 mu m;

C. mixing and granulating: mixing the extract, the yam powder and the medlar powder according to the weight ratio, adding water for humidification, and granulating;

D. drying, granulating and tabletting: drying at 40-55 deg.C, mixing with magnesium stearate and food additive, and tabletting.

Preferably, in order to further improve the absorption effect of the human body and improve the drug effect of each component of the tabletted candy, the step A further comprises crushing the maca extract, the dried oyster extract, the dogwood extract, the angelica sinensis extract, the penis cervi extract, the astragalus membranaceus extract, the polygonatum sibiricum extract and the cistanche extract, and crushing the extracts to the particle size of less than 1 mu m.

Preferably, the dried oyster extract and the sealwort extract are prepared by a water boiling extraction and concentration method.

Preferably, the ginseng peptide is extracted by the following method:

pulverizing dried Ginseng radix, extracting with composite organic solvent at 35 deg.C under microwave for 25 min, and filtering to obtain filtrate;

extracting with swelling solvent;

performing compound enzymolysis;

two-phase extraction;

separating and purifying to obtain the ginseng peptide.

Compared with the prior art, the invention has the following advantages and beneficial effects:

1. the tablet candy disclosed by the invention directly adopts the ginseng peptide as a main component, and the vast majority of the rest components adopt the extract, so that the effective substances are conveniently absorbed by a human body; the ingredients have synergistic effect, and the tablet candy is beneficial to improving the effects of nourishing yin and tonifying yang.

2. The tablet candy has good effects of improving immunity, promoting metabolism, tonifying kidney and nourishing lung, thereby having the effects of tonifying qi and kidney, enhancing immunity, protecting cardiovascular and cerebrovascular systems and nourishing internal organs.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to examples, and the exemplary embodiments and descriptions thereof are only used for explaining the present invention and are not used as limitations of the present invention.

Example 1

A ginseng small molecule peptide tablet candy comprises the following components in parts by weight: 20-25 parts of ginseng peptide, 5-9 parts of maca extract, 4-5 parts of dried oyster extract, 10-15 parts of yam powder, 5-9 parts of dogwood extract, 8-11 parts of angelica extract, 7-9 parts of penis cervi extract, 7-9 parts of deer kidney extract, 2-4 parts of astragalus extract, 3-7 parts of wolfberry powder, 3-7 parts of rhizoma polygonati extract and 3-7 parts of cistanche extract, wherein the particle sizes of the yam powder and the wolfberry powder are between 10 and 12 mu m. The ginseng peptide is a small molecular peptide, is convenient for human body to absorb and can enhance immunity; maca has the effects of tonifying kidney and strengthening yang, tonifying lung and promoting fluid production, and has a remarkable effect of balancing human hormone secretion; the dried Concha Ostreae has effects in strengthening liver, removing toxic substances, improving sexual function, purifying blood stasis, relieving fatigue, and nourishing skin; corni fructus has effects of diminishing inflammation, resisting bacteria, reducing blood sugar, invigorating kidney, and stopping nocturnal emission; radix Angelicae sinensis has effects in loosening bowel to relieve constipation, promoting blood circulation, removing blood stasis, regulating menstruation, and relieving pain; radix rehmanniae Preparata has effects of lowering blood pressure, inhibiting thrombosis, and replenishing blood; the penis cervi can produce sperms, enrich the blood, strengthen the brain and tonify the kidney; the deer kidney can tonify kidney essence, strengthen kidney yang, and strengthen waist and knee; radix astragali has effects in invigorating qi, arresting sweating, inducing diuresis, relieving swelling, and expelling pus; fructus Lycii has effects in nourishing liver and kidney, replenishing vital essence, and improving eyesight; rhizoma Polygonati has effects in invigorating qi, nourishing yin, invigorating spleen, moistening lung, and invigorating kidney; cistanchis herba has effects of invigorating kidney yang, replenishing essence and blood, and loosening bowel to relieve constipation. The Chinese yam powder is directly adopted, so that the immunity of a human body can be improved, the gelatinization performance of the Chinese yam powder can be utilized to enhance the stability of the tablet candy, and the disintegration of the tablet candy is avoided. The tablet candy prepared by the formula has good effects of improving immunity, promoting metabolism, tonifying kidney and nourishing lung, has the effects of tonifying qi and kidney, enhancing immunity, protecting cardiovascular and cerebrovascular systems and nourishing internal organs, and has a good effect.

The following components and parts by weight can also be added: 4-5 parts of maltodextrin and 5-8 parts of food additives so as to facilitate granulation.

Example 2

A ginseng small molecule peptide tablet candy comprises the following components in parts by weight: 22 parts of ginseng peptide, 6 parts of maca extract, 4 parts of dried oyster extract, 12 parts of yam powder, 7 parts of dogwood extract, 10 parts of Chinese angelica extract, 8 parts of deer penis extract, 8 parts of deer kidney extract, 3 parts of astragalus extract, 5 parts of wolfberry powder, 5 parts of sealwort extract and 5 parts of cistanche extract, wherein the particle sizes of the yam powder and the wolfberry powder are between 10 and 12 micrometers.

Example 3

A ginseng small molecule peptide tablet candy comprises the following components in parts by weight: the traditional Chinese medicine composition comprises 25 parts of ginseng peptide, 5 parts of maca extract, 4 parts of dried oyster extract, 10 parts of yam powder, 5 parts of dogwood extract, 8 parts of Chinese angelica extract, 7 parts of deer penis extract, 7 parts of deer kidney extract, 2 parts of astragalus extract, 3 parts of wolfberry powder, 3 parts of sealwort extract and 3 parts of cistanche extract, wherein the particle sizes of the yam powder and the wolfberry powder are 10-12 mu m.

Example 4

A ginseng small molecule peptide tablet candy comprises the following components in parts by weight: the traditional Chinese medicine composition comprises 20 parts of ginseng peptide, 9 parts of maca extract, 5 parts of dried oyster extract, 15 parts of yam powder, 9 parts of dogwood extract, 11 parts of Chinese angelica extract, 9 parts of deer penis extract, 9 parts of deer kidney extract, 4 parts of astragalus extract, 7 parts of wolfberry fruit powder, 7 parts of sealwort extract and 7 parts of cistanche extract, wherein the particle sizes of the yam powder and the wolfberry fruit powder are 10-12 mu m.

Example 5

A purification preparation process of ginseng small molecule peptide tablet candy comprises the following steps:

A. preparation of the extract: producing the extract of any of the above embodiments from raw materials;

B. preparation of powdery raw materials: grinding the dried yam and medlar powder to a particle size of between 10 and 12 mu m;

C. mixing and granulating: the extract, the yam powder and the medlar powder are mixed according to the weight proportion in any one of the embodiments, and are humidified by adding water and then are granulated;

D. drying, granulating and tabletting: drying at 40-55 deg.C, mixing with magnesium stearate and food additive, and tabletting. Magnesium stearate can be used as food additive.

Step A, also comprises a crushed maca extract, a dried oyster extract, a dogwood extract, an angelica extract, a deer penis extract, a deer kidney extract, a astragalus extract, a polygonatum extract and a cistanche extract, wherein the crushed extracts have the particle size of less than 1 mu m. The extract is extracted and dried and then needs to be crushed, and the smaller the crushed particle size is, the more obvious the drug effect absorption is. The dried oyster extract and the sealwort extract are prepared by a water boiling extraction and concentration method.

The ginseng peptide is extracted by the following method: pulverizing dried Ginseng radix, extracting with composite organic solvent at 35 deg.C under microwave for 25 min, and filtering to obtain filtrate; extracting with swelling solvent; performing compound enzymolysis; two-phase extraction; separating and purifying to obtain the ginseng peptide.

The above-mentioned embodiments are intended to illustrate the objects, technical solutions and advantages of the present invention in further detail, and it should be understood that the above-mentioned embodiments are merely exemplary embodiments of the present invention, and are not intended to limit the scope of the present invention, and any modifications, equivalent substitutions, improvements and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.