阅读说明：本技术 一种母畜用产后消炎促孕灌注液及制备和使用方法 (Inflammation diminishing and pregnancy promoting perfusate for female animals after delivery and preparation and use methods thereof ) 是由 张卫刚 汪德刚 杜书伟 李海丽 牛强 李雪杰 赛利娜 燕松建 于 2020-10-26 设计创作，主要内容包括：本发明涉及一种母畜用产后消炎促孕灌注液及制备和使用方法,本发明提供了一种补充维生素类混合型饲料添加剂,由以下质量百分比组份构成：维生素B1 2.5%—5.5%,维生素B2 1.3%—3.5%,维生素B12 2.5%—4.1%,维生素D3 3.1%—5.3%,维生素E 3.3%—4.5%,维生素A 2.5%-5%,维生素K3 3.5%—4.7%,黄曲霉毒素B1分解酶3%—8.8%,复合产酶益生素4%—6.7%,牛磺酸11%—23%,余量为氨基酸。其制备方法包括原料混合,成型加工及封装等三个步骤。本发明一方面可有效且全面的提高饲料中营养成分的全面性及均衡性,并有助于提供饲料中营养成分的综合吸收利用率；另一方面有助于对畜禽饲料中霉变变质的毒素进行有效解毒,并可对畜禽自身的炎症等疾病进行有效的预防和辅助治疗,从而极大的改善和提高畜禽的健康状态,降低因中毒、疾病造成畜禽发育不良及死亡率高等养殖风险和损失。(The invention relates to a postpartum inflammation diminishing and pregnancy promoting perfusate for female animals and a preparation and use method thereof, and provides a vitamin supplementing mixed feed additive which comprises the following components in percentage by mass: 12.5-5.5% of vitamin B, 21.3-3.5% of vitamin B, 122.5-4.1% of vitamin B, 33.1-5.3% of vitamin D, 3.3-4.5% of vitamin E, 2.5-5% of vitamin A, 33.5-4.7% of vitamin K, 3-8.8% of aflatoxin B1 catabolic enzyme, 4-6.7% of complex enzyme-producing probiotics, 11-23% of taurine and the balance of amino acids. The preparation method comprises three steps of raw material mixing, molding processing, packaging and the like. On one hand, the comprehensive utilization method can effectively and comprehensively improve the comprehensiveness and the balance of the nutrient components in the feed, and is favorable for providing the comprehensive absorption utilization rate of the nutrient components in the feed; on the other hand, the feed additive is beneficial to effectively detoxifying mildewed and deteriorated toxins in the livestock and poultry feed, and can effectively prevent and assist in treating diseases such as inflammation of the livestock and poultry, so that the health state of the livestock and poultry is greatly improved and improved, and the breeding risks and losses such as poor development and high mortality of the livestock and poultry caused by poisoning and diseases are reduced.)

1. A vitamin-supplementing mixed feed additive is characterized in that: the postpartum inflammation diminishing and pregnancy promoting perfusate for the female livestock for eliminating the inflammation of the female livestock comprises the following components in percentage by mass: 12.5-5.5% of vitamin B, 21.3-3.5% of vitamin B, 122.5-4.1% of vitamin B, 33.1-5.3% of vitamin D, 3.3-4.5% of vitamin E, 2.5-5% of vitamin A, 33.5-4.7% of vitamin K, 3-8.8% of aflatoxin B1 catabolic enzyme, 4-6.7% of complex enzyme-producing probiotics, 11-23% of taurine and the balance of amino acids.

2. The vitamin-supplementing mixed feed additive according to claim 1, wherein: the aflatoxin B1 decomposition enzyme is additionally provided with aflatoxin B1 degradation flora with the total amount of no more than 30% of the consumption of aflatoxin B1 decomposition enzyme.

3. The vitamin-supplementing mixed feed additive according to claim 1, wherein: the aflatoxin B1 degrading flora comprises lactobacillus, yeast and sticky bacteria which are mixed in any proportion.

4. The vitamin-supplementing mixed feed additive according to claim 1, wherein: the amino acid comprises at least two of lysine, tryptophan, phenylalanine, methionine, threonine, isoleucine, leucine, valine, arginine and histidine mixed at a ratio of 1: 1.

5. The vitamin-supplementing mixed feed additive according to claim 1, which is characterized in that: the amino acid is additionally provided with an organic binder accounting for 30-60% of the total amount of the amino acid.

6. The vitamin-supplementing mixed feed additive according to claim 1, which is characterized in that: the organic binder is any one of glycerol, honey, vegetable oil and animal oil.

7. A preparation method of a vitamin-supplementing mixed feed additive is characterized by comprising the following steps: the preparation method of the vitamin-supplementing mixed feed additive comprises the following steps:

s1, mixing the raw materials, namely, firstly, mechanically stirring and mixing vitamin B1, vitamin B2, vitamin B12, vitamin D3, vitamin E, vitamin A and vitamin K3 in a constant-temperature environment with the oxygen content not more than 10% and the temperature of 10-25 ℃ to obtain a vitamin mixture, and preserving at constant temperature; mechanically stirring and mixing aflatoxin B1 decomposition enzyme and compound enzyme-producing probiotics in a constant-temperature environment with oxygen content not more than 10% and temperature of 0-5 deg.C to obtain auxiliary mixture, and storing at constant temperature; mixing taurine and amino acid by ultrasonic waves at the constant temperature of 10-25 ℃ to obtain a nutritional agent, then adding a vitamin mixture into an auxiliary mixing agent, mechanically stirring and mixing at the constant temperature of 0-5 ℃ under the condition that the oxygen content is not more than 10%, and finally adding the mixed material of the vitamin mixture and the auxiliary mixing agent into the nutritional agent at a constant speed of 0.5-1.1 m/min and uniformly mixing to obtain a primary mixed material;

s2, molding, namely adding the primary mixed material prepared in the step S1 into a press molding device, performing press molding on the primary mixed material through the press molding device to obtain a solid granular finished product material, and storing the solid granular finished product material in a constant temperature environment with the temperature of-10-0 ℃, the oxygen content of not more than 5% and the air humidity of not more than 40%;

and S3, packaging, namely packaging the finished granular material obtained in the step S2 by packaging equipment to obtain a finished product, and storing the packaged finished product in an environment at the temperature of-10 ℃.

8. The preparation method of the vitamin-supplementing mixed feed additive according to claim 7, wherein the vitamin-supplementing mixed feed additive comprises the following steps: in the step S2, the pressure value is 3-5 kg/cm during the pressing and molding operation²。

9. The preparation method of the vitamin-supplementing mixed feed additive according to claim 7, wherein the vitamin-supplementing mixed feed additive comprises the following steps: in the step S2, the particle size of the prepared solid granular finished material is 3-20 mm.

Technical Field

The invention relates to a postpartum inflammation diminishing and pregnancy promoting perfusate for female animals and a preparation method and a using method thereof, belonging to the technical field of traditional Chinese medicine biological preparations.

Background

The existing livestock postpartum anti-inflammation pregnancy-promoting products have various markets and disordered product quality and curative effect, and are intensively embodied in that on one hand, part of the products are marked with Chinese medicine flags and added with western medicine components, so that the side effect is great; on the other hand, partial traditional Chinese medicine products have single effect, unobvious drug effect, easy deterioration and precipitation of drug liquid, poor using effect, high using risk and relatively high storage and transportation difficulty and cost, so that the products on the current market often cannot effectively solve a series of problems of inflammation, incomplete exposure, no return, repeated mating and no pregnancy of female animals, and the like, and simultaneously easily cause secondary infection, seriously influence the smooth development of breeding work, and increase the risk of illness and the daily management cost of livestock.

The invention aims to provide the inflammation diminishing and pregnancy promoting perfusate for the female animals after delivery and the preparation and use methods thereof, so as to overcome the defects of the current products and meet the requirements of practical use and livestock breeding work.

In order to achieve the purpose, the invention provides the following technical scheme:

a vitamin-supplementing mixed feed additive comprises the following components in percentage by mass: 12.5-5.5% of vitamin B, 21.3-3.5% of vitamin B, 122.5-4.1% of vitamin B, 33.1-5.3% of vitamin D, 3.3-4.5% of vitamin E, 2.5-5% of vitamin A, 33.5-4.7% of vitamin K, 3-8.8% of aflatoxin B1 catabolic enzyme, 4-6.7% of complex enzyme-producing probiotics, 11-23% of taurine and the balance of amino acids.

Furthermore, the aflatoxin B1 degrading flora with the total amount of aflatoxin B1 degrading enzyme not more than 30% of the amount of aflatoxin B1 degrading enzyme is additionally arranged.

Furthermore, the aflatoxin B1 degrading flora comprises lactobacillus, yeast and sticky bacteria which are mixed in any proportion.

Further, the amino acid comprises at least two of lysine, tryptophan, phenylalanine, methionine, threonine, isoleucine, leucine, valine, arginine and histidine which are mixed in a ratio of 1: 1.

Furthermore, the amino acid is additionally provided with an organic binder accounting for 30-60 percent of the total amount of the amino acid.

Further, the organic binder is any one of glycerol, honey, vegetable oil and animal oil.

A preparation method of a vitamin-supplementing mixed feed additive comprises the following steps:

s1, mixing the raw materials, namely, firstly, mechanically stirring and mixing vitamin B1, vitamin B2, vitamin B12, vitamin D3, vitamin E, vitamin A and vitamin K3 in a constant-temperature environment with the oxygen content not more than 10% and the temperature of 10-25 ℃ to obtain a vitamin mixture, and preserving at constant temperature; mechanically stirring and mixing aflatoxin B1 decomposition enzyme and compound enzyme-producing probiotics in a constant-temperature environment with oxygen content not more than 10% and temperature of 0-5 deg.C to obtain auxiliary mixture, and storing at constant temperature; mixing taurine and amino acid by ultrasonic waves at the constant temperature of 10-25 ℃ to obtain a nutritional agent, then adding a vitamin mixture into an auxiliary mixing agent, mechanically stirring and mixing at the constant temperature of 0-5 ℃ under the condition that the oxygen content is not more than 10%, and finally adding the mixed material of the vitamin mixture and the auxiliary mixing agent into the nutritional agent at a constant speed of 0.5-1.1 m/min and uniformly mixing to obtain a primary mixed material;

s2, molding, namely adding the primary mixed material prepared in the step S1 into a press molding device, performing press molding on the primary mixed material through the press molding device to obtain a solid granular finished product material, and storing the solid granular finished product material in a constant temperature environment with the temperature of-10-0 ℃, the oxygen content of not more than 5% and the air humidity of not more than 40%;

and S3, packaging, namely packaging the finished granular material obtained in the step S2 by packaging equipment to obtain a finished product, and storing the packaged finished product in an environment at the temperature of-10 ℃.

Further, in the step S2, the pressure value is 3-5 kg/cm during the pressing and molding operation²。

Further, in the step S2, the prepared solid granular finished material has a particle size of 3 to 20 mm.

On one hand, the invention can effectively and comprehensively improve the comprehensiveness and the balance of the nutrient components in the feed, is favorable for providing the comprehensive absorption and utilization rate of the nutrient components in the feed and promotes the growth and development of the livestock and poultry; on the other hand, the feed additive is beneficial to effectively detoxifying mildewed and deteriorated toxins in the livestock and poultry feed, and can effectively prevent and assist in treating diseases such as inflammation of the livestock and poultry, so that the health state of the livestock and poultry is greatly improved and improved, and the breeding risks and losses such as poor development and high mortality of the livestock and poultry caused by poisoning and diseases are reduced.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.

FIG. 1 is a flow chart of the manufacturing process of the present invention.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

A vitamin-supplementing mixed feed additive comprises the following components in percentage by mass: 12.5 percent of vitamin B, 21.3 percent of vitamin B, 122.5 percent of vitamin B, 33.1 percent of vitamin D, 3.3 percent of vitamin E, 2.5 percent of vitamin A, 33.5 percent of vitamin K, 3 percent of aflatoxin B1 catabolic enzyme, 4 percent of complex enzyme-producing probiotics, 11 percent of taurine and the balance of amino acid.

In this embodiment, the aflatoxin B1 lyase additionally sets aflatoxin B1 degrading flora with a total amount of no more than 30% of the aflatoxin B1 lyase.

Preferably, the aflatoxin B1 degrading flora comprises lactobacillus, yeast and sticky bacteria which are mixed in any proportion.

It is noted that the amino acids include at least two of lysine, tryptophan, phenylalanine, methionine, threonine, isoleucine, leucine, valine, arginine and histidine at a ratio of 1: 1.

And at the same time, the amino acid is additionally provided with an organic binder accounting for 30-60 percent of the total amount of the amino acid.

Preferably, the organic binder is vegetable oil.

As shown in fig. 1, a preparation method of a vitamin-supplementing mixed feed additive comprises the following steps:

s1, mixing the raw materials, namely, firstly, mechanically stirring and mixing vitamin B1, vitamin B2, vitamin B12, vitamin D3, vitamin E, vitamin A and vitamin K3 in a constant-temperature environment with the oxygen content of 0 and the temperature of 10 ℃ to obtain a vitamin mixture, and preserving at constant temperature; mechanically stirring and mixing aflatoxin B1 decomposition enzyme and compound enzyme-producing probiotics in a constant-temperature environment with oxygen content of 0 and temperature of 0 ℃ to obtain an auxiliary mixing agent, and preserving at constant temperature; mixing taurine and amino acid by ultrasonic waves under the constant temperature environment of 10 ℃ to obtain a nutritional agent, then adding a vitamin mixture into an auxiliary mixture, mechanically stirring and mixing under the constant temperature environment of 0 ℃ and 0 ℃ under the condition that the oxygen content is 0, and finally adding the mixed substance of the vitamin mixture and the auxiliary mixture into the nutritional agent at a constant speed of 0.5 m/min and uniformly mixing to obtain a primary mixed material;

s2, molding, namely adding the primary mixed material prepared in the step S1 into a press molding device, performing press molding on the primary mixed material by the press molding device to obtain a solid granular finished product material, and storing the solid granular finished product material in a constant-temperature environment with the temperature of-10 ℃, the oxygen content of 0 and the air humidity of 10%;

and S3, packaging, namely packaging the finished granular material obtained in the step S2 by packaging equipment to obtain a finished product, and storing the packaged finished product in an environment with the temperature of-10 ℃.

Wherein, in the step S2, the pressure value is 3kg/cm during the pressing and molding operation²(ii) a The particle size of the prepared solid granular finished material is 3 mm.

Example 2

A vitamin-supplementing mixed feed additive comprises the following components in percentage by mass: 15.5 percent of vitamin B, 23.5 percent of vitamin B, 124.1 percent of vitamin B, 35.3 percent of vitamin D, 4.5 percent of vitamin E, 5 percent of vitamin A, 34.7 percent of vitamin K, 8.8 percent of aflatoxin B1 catabolic enzyme, 6.7 percent of complex enzyme-producing probiotics, 23 percent of taurine and the balance of amino acid.

In this embodiment, the aflatoxin B1 degrading enzyme is further provided with an aflatoxin B1 degrading flora, the total amount of which is not more than 30% of the amount of the aflatoxin B1 degrading enzyme, and the aflatoxin B1 degrading flora comprises lactobacillus, yeast and sticky bacteria which are mixed in any proportion.

The amino acids include lysine, tryptophan, phenylalanine and methionine mixed in a ratio of 1: 1.

It is noted that the amino acid is additionally provided with an organic binder accounting for 60 percent of the total amount of the amino acid, and the organic binder is honey.

As shown in fig. 1, a preparation method of a vitamin-supplementing mixed feed additive comprises the following steps:

s1, mixing the raw materials, namely, firstly, mechanically stirring and mixing vitamin B1, vitamin B2, vitamin B12, vitamin D3, vitamin E, vitamin A and vitamin K3 in a constant-temperature environment with the oxygen content of 10% and the temperature of 25 ℃ to obtain a vitamin mixture, and preserving at constant temperature; mechanically stirring and mixing aflatoxin B1 decomposition enzyme and compound enzyme-producing probiotics under the constant temperature environment with the oxygen content of 10% and the temperature of 5 ℃ to obtain an auxiliary mixing agent, and preserving at constant temperature; mixing taurine and amino acid by ultrasonic waves at a constant temperature of 25 ℃ to obtain a nutritional agent, adding a vitamin mixture into an auxiliary mixture, mechanically stirring and mixing at a constant temperature of 5 ℃ under the condition that the oxygen content is 10%, and finally adding the mixed substance of the vitamin mixture and the auxiliary mixture into the nutritional agent at a constant speed of 1.1 m/min and uniformly mixing to obtain a primary mixed material;

s2, molding, namely adding the primary mixed material prepared in the step S1 into a press molding device, performing press molding on the primary mixed material by the press molding device to obtain a solid granular finished product material, and storing the solid granular finished product material in a constant-temperature environment with the temperature of 0 ℃, the oxygen content of 5% and the air humidity of 40%;

and S3, packaging, namely packaging the finished granular material obtained in the step S2 by packaging equipment to obtain a finished product, and storing the packaged finished product in an environment with the temperature of 10 ℃.

It should be noted that in the step S2, when performing the compression molding operation, the pressure value is 5 kg/cm; the particle size of the prepared solid granular finished material is 20 mm.

Example 3

A vitamin-supplementing mixed feed additive comprises the following components in percentage by mass: vitamin B13%, vitamin B22.5%, vitamin B123.1%, vitamin D34.3%, vitamin E3.8%, vitamin A3.5%, vitamin K34.3%, aflatoxin B1 lyase 6.8%, enzyme-producing complex probiotics 5.7%, taurine 19%, and the balance amino acids.

In this embodiment, the aflatoxin B1 lyase additionally sets aflatoxin B1 degrading flora with a total amount of no more than 30% of the aflatoxin B1 lyase.

Wherein the aflatoxin B1 degrading flora comprises lactobacillus, yeast and myxobacteria which are mixed in any proportion.

Meanwhile, the amino acid comprises lysine, tryptophan, phenylalanine, methionine, threonine, isoleucine, leucine, valine, arginine and histidine which are mixed in a ratio of 1: 1.

The amino acid is additionally provided with an organic binder accounting for 45 percent of the total amount of the amino acid; and the organic binder is glycerol.

As shown in fig. 1, a preparation method of a vitamin-supplementing mixed feed additive comprises the following steps:

s1, mixing the raw materials, namely, firstly, mechanically stirring and mixing vitamin B1, vitamin B2, vitamin B12, vitamin D3, vitamin E, vitamin A and vitamin K3 in a constant-temperature environment with the oxygen content of 5% and the temperature of 20 ℃ to obtain a vitamin mixture, and preserving at constant temperature; mechanically stirring and mixing aflatoxin B1 decomposition enzyme and compound enzyme-producing probiotics under the constant temperature environment with the oxygen content of 8% and the temperature of 3 ℃ to obtain an auxiliary mixing agent, and preserving at constant temperature; mixing taurine and amino acid by ultrasonic waves at a constant temperature of 15 ℃ to obtain a nutritional agent, adding a vitamin mixture into an auxiliary mixture, mechanically stirring and mixing at a constant temperature of 3 ℃ under the condition that the oxygen content is 8%, and finally adding the mixed substance of the vitamin mixture and the auxiliary mixture into the nutritional agent at a constant speed of 0.9 m/min and uniformly mixing to obtain a primary mixed material;

s2, molding, namely adding the primary mixed material prepared in the step S1 into a press molding device, performing press molding on the primary mixed material by the press molding device to obtain a solid granular finished product material, and storing the solid granular finished product material in a constant temperature environment with the temperature of-5 ℃, the oxygen content of 3% and the air humidity of 30%;

and S3, packaging, namely packaging the finished granular material obtained in the step S2 by packaging equipment to obtain a finished product, and storing the packaged finished product in an environment with the temperature of 0 ℃.

Wherein, in the step S2, the pressure value is 4.5kg/cm during the pressing and molding operation²(ii) a And the particle size of the prepared solid granular finished material is 10 mm.

Example 4

A vitamin-supplementing mixed feed additive comprises the following components in percentage by mass: 14.3 percent of vitamin B, 22.6 percent of vitamin B, 123.6 percent of vitamin B, 34.1 percent of vitamin D, 3.8 percent of vitamin E, 3.2 percent of vitamin A, 34.4 percent of vitamin K, 6.1 percent of aflatoxin B1 catabolic enzyme, 5.5 percent of complex enzyme-producing probiotics, 21 percent of taurine and the balance of amino acid.

In this embodiment, the aflatoxin B1 lyase additionally sets aflatoxin B1 degrading flora with a total amount of no more than 30% of the aflatoxin B1 lyase.

Preferably, the aflatoxin B1 degrading flora comprises lactobacillus, yeast and sticky bacteria which are mixed in any proportion.

In this example, the amino acids include lysine, tryptophan, leucine, valine, arginine, and histidine at a ratio of 1: 1.

In addition, the amino acid is additionally provided with an organic binder accounting for 30-60 percent of the total amount of the amino acid.

Preferably, the organic binder is animal oil.

As shown in fig. 1, a preparation method of a vitamin-supplementing mixed feed additive comprises the following steps:

s1, mixing the raw materials, namely, firstly, mechanically stirring and mixing vitamin B1, vitamin B2, vitamin B12, vitamin D3, vitamin E, vitamin A and vitamin K3 in a constant-temperature environment with the oxygen content of 8% and the temperature of 15 ℃ to obtain a vitamin mixture, and preserving at constant temperature; mechanically stirring and mixing aflatoxin B1 decomposition enzyme and compound enzyme-producing probiotics at oxygen content of 5% and temperature of 1 deg.C under constant temperature environment to obtain auxiliary mixture, and storing at constant temperature; mixing taurine and amino acid by ultrasonic waves at a constant temperature of 18 ℃ to obtain a nutritional agent, adding a vitamin mixture into an auxiliary mixture, mechanically stirring and mixing at a constant temperature of 3 ℃ under the condition that the oxygen content is 8%, and finally adding the mixed substance of the vitamin mixture and the auxiliary mixture into the nutritional agent at a constant speed of 0.6 m/min and uniformly mixing to obtain a primary mixed material;

s2, molding, namely adding the primary mixed material prepared in the step S1 into a press molding device, performing press molding on the primary mixed material by the press molding device to obtain a solid granular finished product material, and storing the solid granular finished product material in a constant temperature environment with the temperature of-8 ℃, the oxygen content of 3% and the air humidity of 20%;

and S3, packaging, namely packaging the finished granular material obtained in the step S2 by packaging equipment to obtain a finished product, and storing the packaged finished product in an environment with the temperature of 5 ℃.

It is to be noted that, in the step S2, the pressure value is 4.2kg/c during the pressing and molding operationm²(ii) a Meanwhile, the particle size of the prepared solid granular finished material is 15 mm.

On one hand, the invention can effectively and comprehensively improve the comprehensiveness and the balance of the nutrient components in the feed, is favorable for providing the comprehensive absorption and utilization rate of the nutrient components in the feed and promotes the growth and development of the livestock and poultry; on the other hand, the feed additive is beneficial to effectively detoxifying mildewed and deteriorated toxins in the livestock and poultry feed, and can effectively prevent and assist in treating diseases such as inflammation of the livestock and poultry, so that the health state of the livestock and poultry is greatly improved and improved, and the breeding risks and losses such as poor development and high mortality of the livestock and poultry caused by poisoning and diseases are reduced.

The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.