阅读说明：本技术 一种改善衰老的组织注射液 (Tissue injection for improving aging ) 是由 刘卓 李显明 李彬 秦永平 魏淑娟 于 2021-08-03 设计创作，主要内容包括：本发明公开了一种改善衰老的组织注射液,按照质量浓度计包括如下物质：胶原蛋白5-10mg/ml；透明质酸钠4-8mg/ml；氨甲环酸5-10mg/ml；谷胱甘肽10-30mg/ml；L-肌肽2-4mg/ml；甘氨酸0.1-0.2mg/ml；脯氨酸0.2-0.4mg/ml；利多卡因5-10mg/ml；氯化钠9mg/ml。本发明通过增加胶原蛋白及透明质酸钠,能够快速补机体流失的蛋白及玻尿酸,同时形成组织腔隙刺激自体组织增生,促进注射部分组织丰盈,L-肌肽,氨甲环酸、谷胱甘肽抗炎、抗氧化,提高皮肤对环境的适应性,减少色沉,使得皮肤更加健康有光泽,甘氨酸、脯氨酸增加蛋白合成营养,能够为皮肤组织细胞提供营养,美容效果更加持久。在注射过程中由于增了利多卡因,能够减少注射疼痛和不适感。(The invention discloses a tissue injection for improving aging, which comprises the following substances in percentage by mass: collagen 5-10 mg/ml; 4-8mg/ml of sodium hyaluronate; 5-10mg/ml tranexamic acid; 10-30mg/ml of glutathione; 2-4mg/ml of L-carnosine; 0.1-0.2mg/ml of glycine; proline 0.2-0.4 mg/ml; 5-10mg/ml of lidocaine; sodium chloride 9 mg/ml. According to the invention, by adding the collagen and the sodium hyaluronate, the protein and the hyaluronic acid which are lost by an organism can be quickly supplemented, a tissue cavity is formed to stimulate autologous tissue proliferation, the tissue plumpness of an injection part is promoted, the L-carnosine, tranexamic acid and glutathione are anti-inflammatory and antioxidant, the adaptability of the skin to the environment is improved, the color deposition is reduced, the skin is healthier and glossy, the glycine and the proline increase the protein synthesis nutrition, the nutrition can be provided for skin tissue cells, and the beautifying effect is more durable. The injection pain and discomfort can be reduced due to the addition of lidocaine during the injection process.)

1. An aging-improving tissue injection, characterized in that: the material comprises the following substances by mass concentration:

collagen 5-10 mg/ml;

4-8mg/ml of sodium hyaluronate;

5-10mg/ml tranexamic acid;

10-30mg/ml of glutathione;

2-4mg/ml of L-carnosine;

0.1-0.2mg/ml of glycine;

proline 0.2-0.4 mg/ml;

5-10mg/ml of lidocaine;

sodium chloride 9 mg/ml.

2. The tissue injection for improving aging as set forth in claim 1, wherein: the material comprises the following substances by mass concentration:

collagen 10 mg/ml;

8mg/ml of sodium hyaluronate;

5mg/ml of tranexamic acid;

glutathione is 10 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml.

3. The tissue injection for improving aging as set forth in claim 1, wherein: the material comprises the following substances by mass concentration:

collagen 5 mg/ml;

4mg/ml of sodium hyaluronate;

10mg/ml of tranexamic acid;

glutathione is 30 mg/ml;

2mg/ml of L-carnosine;

glycine 0.1 mg/ml;

proline 0.2 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml.

4. The tissue injection for improving aging as set forth in claim 1, wherein: the material comprises the following substances by mass concentration:

4mg/ml of sodium hyaluronate;

5mg/ml of tranexamic acid;

glutathione is 20 mg/ml;

2mg/ml of L-carnosine;

glycine 0.1 mg/ml;

proline 0.2 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml.

5. The tissue injection for improving aging as set forth in claim 1, wherein: the material comprises the following substances by mass concentration:

collagen 10 mg/ml;

6mg/ml of sodium hyaluronate;

10mg/ml of tranexamic acid;

glutathione is 30 mg/ml;

2mg/ml of L-carnosine;

glycine 0.1 mg/ml;

proline 0.2 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml.

Technical Field

The invention belongs to the technical field of beauty injections, and particularly relates to a tissue injection for improving aging.

Background

Beauty is the nature of human beings, but with the increase of age, the skin gradually ages with the age, protein in skin tissues is lost, the current situation that the skin is dry, pigmentation and wrinkles are increased is formed, and the skin is glossy and elastic at a young age and does not return again.

In order to keep the skin young, the modern society has an increasing number of people who choose to maintain the skin state by means of drug injection. The existing injection beautifying method usually adopts collagen and hyaluronic acid for filling, and has single mode and limited effect.

Disclosure of Invention

The present invention has been made to solve the above-mentioned problems occurring in the prior art, and an object of the present invention is to provide an injection for tissue for improving aging.

In order to achieve the purpose, the invention provides the following technical scheme: an aging-improving tissue injection comprises the following substances in percentage by mass:

collagen 5-10 mg/ml;

4-8mg/ml of sodium hyaluronate;

5-10mg/ml tranexamic acid;

10-30mg/ml of glutathione;

2-4mg/ml of L-carnosine;

0.1-0.2mg/ml of glycine;

proline 0.2-0.4 mg/ml;

5-10mg/ml of lidocaine;

sodium chloride 9 mg/ml.

The invention has the beneficial effects that:

collagen protein: when collagen is injected into the skin, which has been deflated and depressed, syneresis rearranges to approximate the natural collagen fibers in the body. Promoting fibroblasts, capillaries and fat cells in vivo to migrate and grow into the collagen graft, synthesizing self collagen, and finally forming self normal connective tissue to recover the depression and lighten or eliminate wrinkles.

Sodium hyaluronate: sodium hyaluronate is a biological substance inherent to skin, and exogenous injection of sodium hyaluronate can promote the regeneration of skin at the injured part by promoting the proliferation and differentiation of epidermal cells and scavenging oxygen free radicals. The sodium hyaluronate aqueous solution has strong viscoelasticity and lubricity, can reduce water loss, promote blood microcirculation, and is beneficial to the absorption of skin on nutrient substances, thereby preventing skin aging and playing a role in beautifying and resisting wrinkles.

Tranexamic acid: the tranexamic acid is a protease inhibitor, and after the skin is irradiated by ultraviolet rays, the tranexamic acid can inhibit not only tyrosinase enzyme, but also release of prostaglandin PGE2, and prevent melanin aggregation. Can also inhibit the expression of protease activated receptor, thereby preventing the transport and diffusion of melanin. The black-removing and spot-removing efficacy of the vitamin C is about 50 times higher than that of vitamin C, and is about 10 times higher than that of tartaric acid.

Glutathione: glutathione has high inhibition rate on tyrosinase, is an antioxidant and a free radical scavenger, and active sulfydryl in a tripeptide structure of the glutathione can reduce bivalent copper at the enzyme activity center in the tyrosinase into monovalent copper. Thereby reducing the generation of melanin and achieving the whitening effect.

L-carnosine: can promote cell metabolism, delay aging, prevent glycosylation reaction, eliminate active oxygen free Radicals (ROS) formed by excessive oxidation of fatty acid in cell membrane during oxidative stress process, and enhance whitening effect by matching with whitening components.

Glycine proline: essential amino acids for protein synthesis promote regeneration of skin collagen protein and provide nutrient substances.

Preferably, the following substances are included according to mass concentration:

collagen 10 mg/ml;

8mg/ml of sodium hyaluronate;

5mg/ml of tranexamic acid;

glutathione is 10 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml.

Preferably, the following substances are included according to mass concentration:

collagen 5 mg/ml;

4mg/ml of sodium hyaluronate;

10mg/ml of tranexamic acid;

glutathione is 30 mg/ml;

2mg/ml of L-carnosine;

glycine 0.1 mg/ml;

proline 0.2 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml.

Preferably, the following substances are included according to mass concentration:

4mg/ml of sodium hyaluronate;

5mg/ml of tranexamic acid;

glutathione is 20 mg/ml;

2mg/ml of L-carnosine;

glycine 0.1 mg/ml;

proline 0.2 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml.

Preferably, the following substances are included according to mass concentration:

collagen 10 mg/ml;

6mg/ml of sodium hyaluronate;

10mg/ml of tranexamic acid;

glutathione is 30 mg/ml;

2mg/ml of L-carnosine;

glycine 0.1 mg/ml;

proline 0.2 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml.

The invention has the technical effects and advantages that:

according to the invention, by adding the collagen and the sodium hyaluronate, the protein and the hyaluronic acid which are lost by an organism can be quickly supplemented, a tissue cavity is formed to stimulate autologous tissue proliferation, the tissue plumpness of an injection part is promoted, the L-carnosine, tranexamic acid and glutathione are anti-inflammatory and antioxidant, the adaptability of the skin to the environment is improved, the color deposition is reduced, the skin is healthier and glossy, the glycine and the proline increase the protein synthesis nutrition, the nutrition can be provided for skin tissue cells, and the beautifying effect is more durable. The injection pain and discomfort can be reduced due to the addition of lidocaine during the injection process.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

An aging-improving tissue injection comprises the following substances in percentage by mass:

collagen 10 mg/ml;

8mg/ml of sodium hyaluronate;

5mg/ml of tranexamic acid;

glutathione is 10 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml. For filling the frontotemporal part.

Example 2

An aging-improving tissue injection comprises the following substances in percentage by mass:

collagen 5 mg/ml;

4mg/ml of sodium hyaluronate;

10mg/ml of tranexamic acid;

glutathione is 30 mg/ml;

2mg/ml of L-carnosine;

glycine 0.1 mg/ml;

proline 0.2 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml. Used for filling cheeks and cheeks.

Example 3

An aging-improving tissue injection comprises the following substances in percentage by mass:

4mg/ml of sodium hyaluronate;

5mg/ml of tranexamic acid;

glutathione is 20 mg/ml;

2mg/ml of L-carnosine;

glycine 0.1 mg/ml;

proline 0.2 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml. For filling the facial hypodermis.

Example 4

An aging-improving tissue injection comprises the following substances in percentage by mass:

collagen 10 mg/ml;

6mg/ml of sodium hyaluronate;

10mg/ml of tranexamic acid;

glutathione is 30 mg/ml;

2mg/ml of L-carnosine;

glycine 0.1 mg/ml;

proline 0.2 mg/ml;

5mg/ml of lidocaine;

sodium chloride 9 mg/ml. For filling the hands.

Test for aging improving Effect

30 female volunteers of 35-55 years old, dark-skinned, dry and striae are recruited, and the examples (1-4) are randomly given to the corresponding sites of the volunteers and given a follow-up visit for 3-6 months, with the following observations:

according to the data, 30 cases of injection on different parts are observed for 3 months to half a year, the skin color of a volunteer is obviously brightened, fine lines are obviously improved, the skin quality is improved, 1 case shows red and swollen, symptoms disappear after ice compress, other unsuitable symptoms do not exist, and the effect is stable.

According to the invention, by adding the collagen and the sodium hyaluronate, the protein and the hyaluronic acid which are lost by an organism can be quickly supplemented, a tissue cavity is formed to stimulate autologous tissue proliferation, the tissue plumpness of an injection part is promoted, the L-carnosine, tranexamic acid and glutathione are anti-inflammatory and antioxidant, the adaptability of the skin to the environment is improved, the color deposition is reduced, the skin is healthier and glossy, the glycine and the proline increase the protein synthesis nutrition, the nutrition can be provided for skin tissue cells, and the beautifying effect is more durable. The injection pain and discomfort can be reduced due to the addition of lidocaine during the injection process.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.