阅读说明：本技术 噬菌体和转导颗粒 (Bacteriophage and transduction particles ) 是由 J.K.哈贝尔 S.扎博尔克斯 于 2018-11-21 设计创作，主要内容包括：本发明涉及使用DNA(例如,质粒和辅助噬菌体、可移动遗传元件(MGE)、或具有染色体整合的辅助噬菌体基因的质粒)的噬菌体和转导颗粒的生产,以及所述噬菌体、辅助噬菌体、试剂盒、组合物和涉及这些的方法。颗粒可特别用于将有毒的有效载荷递送到靶细菌内用于抗菌作用。实施方案使得能够生产此类颗粒的高纯度组合物用于医学或环境用途以及用于遏制颗粒,其可以用于遏制抗菌作用。(The present invention relates to the production of phage and transduction particles using DNA (e.g., plasmids and helper phage, Mobile Genetic Elements (MGEs), or plasmids with chromosomally integrated helper phage genes), as well as the phage, helper phage, kits, compositions, and methods involving these. The particles are particularly useful for delivering toxic payloads into target bacteria for antimicrobial action. Embodiments enable the production of high purity compositions of such particles for medical or environmental uses and for containment of particles, which may be used to contain antimicrobial effects.)