阅读说明：本技术 镁合金肾动脉支架 (Magnesium alloy renal artery stent ) 是由 王瑞罡 朱世杰 李天晓 李荣福 于 2019-11-15 设计创作，主要内容包括：本发明公开了镁合金肾动脉支架,涉及医疗器械技术领域,包括第一支撑环架与第二支撑环架,轴向固定条上嵌接有支撑片,第一支撑环架与第二支撑环架的外表面均设有凸起带,第二支撑环架的一侧固定连接有柔性网。本发明通过设置镁合金制成的第一支撑环架、第二支撑环架,该肾动脉血管支架能够在血管中降解,可有效减少血管内膜增生、再狭窄、晚期血栓等问题发生的可能性,通过设置柔性网,避免肾动脉血管与大动脉血管结合处再次变窄,第一支撑环架与第二支撑环架无需伸出至大动脉血管内,因而不影响大动脉血管正常运输血液,通过设置凸起带,在一定程度上起到阻止第一支撑环架与第二支撑环架偏移的作用。(The invention discloses a magnesium alloy renal artery stent, which relates to the technical field of medical instruments and comprises a first support ring frame and a second support ring frame, wherein support sheets are embedded on axial fixing strips, the outer surfaces of the first support ring frame and the second support ring frame are respectively provided with a convex belt, and one side of the second support ring frame is fixedly connected with a flexible net. According to the invention, the first support ring frame and the second support ring frame made of magnesium alloy are arranged, the renal artery stent can be degraded in a blood vessel, the possibility of occurrence of problems such as intimal hyperplasia, restenosis, late thrombosis and the like of the blood vessel can be effectively reduced, the flexible net is arranged, the re-narrowing of the joint of the renal artery blood vessel and the aorta blood vessel is avoided, the first support ring frame and the second support ring frame do not need to extend into the aorta blood vessel, and therefore, the normal blood transportation of the aorta blood vessel is not influenced, and the effect of preventing the first support ring frame and the second support ring frame from shifting to a certain extent is achieved by arranging the bulge band.)

1. Magnesium alloy renal artery support includes first support ring frame (1) and second support ring frame (9), its characterized in that: one side fixedly connected with support bar (2) and axial fixity strip (3) of first support ring frame (1), it has support piece (4) to scarf joint on axial fixity strip (3), the surface of first support ring frame (1) and second support ring frame (9) all is equipped with protruding area (10), one side fixedly connected with flexible net (11) of second support ring frame (9).

2. The magnesium alloy renal artery stent of claim 1, wherein: the support bar (2) and the axial fixing bar (3) are far away from one end of the first support ring frame (1) and are fixedly connected with the second support ring frame (9), and the support bar (2) and the axial fixing bar (3) are distributed in an annular array.

3. The magnesium alloy renal artery stent of claim 1, wherein: the arc-shaped fixing strip is characterized in that arc-shaped fixing strips (5) are fixedly connected to the two sides of the supporting piece (4), and the arc-shaped fixing strips (5) are fixedly connected with the supporting piece (2).

4. The magnesium alloy renal artery stent of claim 1, wherein: the outer surface of the support sheet (4) is provided with a drug-loaded layer (6), the outer surface of the drug-loaded layer (6) is sprayed with paclitaxel, the middle of the support sheet (4) is provided with a drug storage cavity (7), rapamycin is arranged in the drug storage cavity (7), and the inner surface of the support sheet (4) is provided with capillary holes (8).

5. The magnesium alloy renal artery stent of claim 1, wherein: one side fixedly connected with circular support body (12) of flexible net (11), the first connecting strip (13) of upper portion fixedly connected with of circular support body (12), the lower part fixedly connected with second connecting strip (18) of circular support body (12).

6. The magnesium alloy renal artery stent of claim 5, wherein: the upper surface of the first connecting strip (13) is fixedly connected with a first limiting ring frame (14), and the lower surface of the second connecting strip (18) is fixedly connected with a second limiting ring frame (17).

7. The magnesium alloy renal artery stent of claim 6, wherein: the lower surface of the first limiting ring frame (14) is fixedly connected with an elastic telescopic strip (16), and the lower end of the elastic telescopic strip (16) is fixedly connected with a second limiting ring frame (17).

8. The magnesium alloy renal artery stent of claim 6, wherein: the upper surface of the first limiting ring frame (14) and the lower surface of the second limiting ring frame (17) are fixedly connected with radiopaque marker rings (15), and the radiopaque marker rings (15) are made of tungsten-gold alloy.

9. The magnesium alloy renal artery stent of claims 1, 3, and 6, wherein: first support ring frame (1), support bar (2), axial fixity strip (3), arc fixed strip (5), second support ring frame (9), first spacing ring frame (14) and second spacing ring frame (17) are made by the magnesium alloy, flexible net (11) are made by the nitinol alloy.

Technical Field

The invention relates to the technical field of medical appliances, in particular to a magnesium alloy renal artery stent.

Background

The renal artery is divided into a left renal artery and a right renal artery which are vertically divided from an abdominal aorta, the lower part of the superior mesenteric artery is 1-2cm and enters the left kidney and the right kidney through the renal hilum respectively, the incidence rate of renal artery vascular stenosis is continuously increased along with the advance of aging in recent years, the renal artery stenosis can cause secondary hypertension and ischemic nephropathy and is also an important cause of renal failure of the old people, the traditional percutaneous transluminal renal angioplasty has higher initial and later restenosis rates when treating the renal artery stenosis, the renal artery endoluminal stent implantation overcomes the defect and has higher success rate, meanwhile, researches show that the stent also obtains better long-term recanalization rate when treating the renal artery stenosis, the renal artery endoluminal stent implantation becomes an important alternative method for surgical renal artery reconstruction because of less safety and complications, the renal artery stent is immature in domestic development, only a few manufacturers can produce the artificial stent, more similar foreign products are imitated, the clinical use still mainly comprises imported foreign products, peripheral vascular stents are mostly adopted for replacing the products, stents specially aiming at renal arteries are not common in the market, renal artery lesions are usually positioned at openings of the renal arteries, and the stents must protrude to the aorta after being implanted by 1-2mm to prevent the junction of the renal artery vessels and the aorta from narrowing, so that the hemodynamics shape of the aorta is obviously influenced, and the influence is particularly great after the bilateral stent implantation is needed.

Although a combined renal artery stent disclosed in chinese patent application publication CN107647938A is formed by combining segmented stents, a certain number of segmented stents can be selected according to the location and range of a lesion to form a renal artery stent with a suitable length, but the renal artery stent still needs to protrude into the aorta to prevent the narrowing of the bifurcation of the blood vessel, and thus the problem that the renal artery stent affects the hemodynamic configuration of the aorta is not solved.

Disclosure of Invention

Technical problem to be solved

Aiming at the defects of the prior art, the invention provides a magnesium alloy renal artery stent, which solves the problems in the background technology.

(II) technical scheme

In order to achieve the purpose, the invention is realized by the following technical scheme: including first support ring frame and second support ring frame, one side fixedly connected with support bar and the axial fixity strip of first support ring frame, the last scarf joint of axial fixity strip has the support piece, first support ring frame all is equipped with protruding area with the surface of second support ring frame, one side fixedly connected with flexible net of second support ring frame.

Optionally, the end, far away from the first support ring frame, of the support bar and the axial fixing bar is fixedly connected with the second support ring frame, and the support bar and the axial fixing bar are distributed in an annular array.

Optionally, the two sides of the supporting sheet are fixedly connected with arc-shaped fixing strips, and the arc-shaped fixing strips are fixedly connected with the supporting sheet.

Optionally, the outer surface of the supporting sheet is provided with a drug-loaded layer, paclitaxel is sprayed on the outer surface of the drug-loaded layer, the middle of the supporting sheet is provided with a drug storage cavity, rapamycin is arranged in the drug storage cavity, and the inner surface of the supporting sheet is provided with pores.

Optionally, one side of the flexible net is fixedly connected with a circular frame body, the upper portion of the circular frame body is fixedly connected with a first connecting strip, and the lower portion of the circular frame body is fixedly connected with a second connecting strip.

Optionally, the upper surface of the first connecting strip is fixedly connected with a first limit ring frame, and the lower surface of the second connecting strip is fixedly connected with a second limit ring frame.

Optionally, the lower surface of the first limit ring frame is fixedly connected with an elastic telescopic strip, and the lower end of the elastic telescopic strip is fixedly connected with the second limit ring frame.

Optionally, a radiopaque marker ring is fixedly connected to each of the upper surface of the first stop collar frame and the lower surface of the second stop collar frame, and the radiopaque marker ring is made of a tungsten-gold alloy.

Optionally, the first support ring frame, the support bars, the axial fixing bars, the arc fixing bars, the second support ring frame, the first limit ring frame and the second limit ring frame are all made of magnesium alloy, and the flexible net is made of nitinol alloy.

(III) advantageous effects

The invention provides a magnesium alloy renal artery stent which has the following beneficial effects:

1. this magnesium alloy renal artery support, first support ring frame through setting up the magnesium alloy and making, the support bar, axial fixity strip and second support ring frame, this renal artery support can degrade in the blood vessel, and have good biocompatibility and stronger holding power, can effectively reduce vascular intimal hyperplasia, restenosis, the possibility that late stage thrombus scheduling problem takes place, furthermore, through setting up flexible net, second support ring frame holds up flexible net with circular support body, the inner wall of renal artery opening part is hugged closely to flexible net, avoid renal artery blood vessel and aorta blood vessel junction to narrow once more, first support ring frame need not to stretch out to the aorta in the blood vessel with second support ring frame, because of not influencing the normal blood of transporting of aorta blood.

2. This magnesium alloy renal artery support through setting up the bellying area, increases the area of contact of first support ring frame and second support ring frame and blood vessel inner wall, increases the friction, plays the effect that prevents first support ring frame and second support ring frame skew to a certain extent, in addition, through setting up first spacing ring frame and second spacing ring frame, the inner wall of aorta is hugged closely to first spacing ring frame and second spacing ring frame, restricts the removal of first support ring frame and second support ring frame.

Drawings

FIG. 1 is a schematic cross-sectional view of the present invention;

FIG. 2 is a schematic structural view of a circular frame according to the present invention;

FIG. 3 is a schematic perspective view of a first support ring and a second support ring according to the present invention;

fig. 4 is a schematic cross-sectional structure of the support sheet of the present invention;

fig. 5 is an enlarged schematic view of the structure at a in fig. 1 according to the present invention.

In the figure: 1. a first support ring frame; 2. a supporting strip; 3. an axial fixing strip; 4. a support sheet; 5. an arc-shaped fixing strip; 6. a drug-loaded layer; 7. a drug storage cavity; 8. capillary pores; 9. a second support ring frame; 10. a raised band; 11. a flexible mesh; 12. a circular frame body; 13. a first connecting bar; 14. a first limit ring frame; 15. a radiopaque marker ring; 16. an elastic expansion strip; 17. a second limit ring frame; 18. a second connecting strip.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

Referring to fig. 1 to 5, the present invention provides a technical solution: the magnesium alloy renal artery stent comprises a first support ring frame 1 and a second support ring frame 9, one side of the first support ring frame 1 is fixedly connected with a support strip 2 and an axial fixing strip 3, one ends, far away from the first support ring frame 1, of the support strip 2 and the axial fixing strip 3 are fixedly connected with the second support ring frame 9, the support strip 2 and the axial fixing strip 3 are distributed in an annular array mode, a support piece 4 is embedded on the axial fixing strip 3, the support piece 4 not only can play a role of supporting the inner wall of a blood vessel, but also can play a role of supporting drugs, a drug-carrying layer 6 is arranged on the outer surface of the support piece 4, paclitaxel is sprayed on the outer surface of the drug-carrying layer 6, a drug storage cavity 7 is formed in the middle of the support piece 4, rapamycin is arranged inside the drug storage cavity 7, capillary holes 8 are formed in the inner surface of the support piece 4, arc-shaped fixing strips 5 are fixedly connected with the two sides of the support piece, the outer surfaces of the first supporting ring frame 1 and the second supporting ring frame 9 are respectively provided with a convex belt 10, the contact area between the first supporting ring frame 1 and the inner wall of the blood vessel and the contact area between the second supporting ring frame 9 and the inner wall of the blood vessel are increased by arranging the convex belts 10, the friction is increased, the function of preventing the deviation to a certain extent is achieved, one side of the second supporting ring frame 9 is fixedly connected with a flexible net 11, the flexible net 11 is made of nitinol, the flexible net 11 and the circular frame body 12 support the flexible net 11 by arranging the flexible net 11, the flexible net 11 is tightly attached to the inner wall of the opening of the renal artery, the joint of the renal artery blood vessel and the aorta blood vessel is prevented from being narrowed again, the first supporting ring frame 1 and the second supporting ring frame 9 do not need to stretch out into the aorta blood vessel, the normal transportation of the blood by the aorta blood vessel is not influenced, one side of the flexible net 11 is fixedly connected with the circular frame body 12, the, the lower part of the circular frame body 12 is fixedly connected with a second connecting strip 18, the upper surface of the first connecting strip 13 is fixedly connected with a first limit ring frame 14, the lower surface of the second connecting strip 18 is fixedly connected with a second limit ring frame 17, the first limit ring frame 14 and the second limit ring frame 17 are arranged to be tightly attached to the inner wall of the aorta to limit the movement of the first support ring frame 1 and the second support ring frame 9, the lower surface of the first limit ring frame 14 is fixedly connected with an elastic expansion strip 16, the lower end of the elastic expansion strip 16 is fixedly connected with the second limit ring frame 17, the upper surface of the first limit ring frame 14 and the lower surface of the second limit ring frame 17 are both fixedly connected with a radiopaque marker ring 15, the radiopaque marker ring 15 is made of tungsten alloy, the first support ring frame 1, the support bar 2, the axial fixing strip 3, the arc fixing strip 5, the second limit ring frame 17, the radiopaque marker ring is fixedly connected with the support bar 1, the axial fixing strip 2, the second support ring frame 9, the first limit ring frame 14 and the second limit ring frame 17 are made of magnesium alloy, the first support ring frame 1, the support bars 2, the axial fixing bars 3 and the second support ring frame 9 made of magnesium alloy are arranged, the renal artery stent can be degraded in the blood vessel, has good biocompatibility and strong supporting force, and can effectively reduce the possibility of occurrence of problems of intimal hyperplasia, restenosis, late thrombosis and the like.

When the device is used, the radiopaque marker rings 15 on the first limiting ring frame 14 and the second limiting ring frame 17 are lightly pressed, the first limiting ring frame 14 and the second limiting ring frame 17 are made to approach each other until the distance between the first limiting ring frame 14 and the second limiting ring frame 17 is equal to the diameter of the second supporting ring frame 9, meanwhile, the elastic expansion strip 16 is shortened, the flexible net 11 and the circular frame body 12 are reduced, the compressed first limiting ring frame 14 and the second limiting ring frame 17 are inserted into the catheter for conveying the stent, the first supporting ring frame 1 is completely retracted into the catheter, the position of the radiopaque marker ring 15 is observed by using medical imaging equipment, one end of the catheter is made to run to the opening of the renal artery, the guide wire is pushed, the first supporting ring frame 1 and the second supporting ring frame 9 are pushed into the renal artery, when the first limiting ring frame 14 and the second limiting ring frame 17 extend out of the inside of the catheter, the elastic expansion strip 16 supports the first limiting ring frame 14 and the second limiting ring frame 17, meanwhile, the first connecting strip 13 and the second connecting strip 18 drive the circular frame body 12 to restore to the original state, the flexible net 11 also restores to the original state, the flexible net 11 is tightly attached to the joint of a renal artery blood vessel and a aorta blood vessel, the renal artery is supported by the first supporting ring frame 1 and the second supporting ring frame 9, the first limiting ring frame 14 and the second limiting ring frame 17 are tightly attached to the inner wall of the aorta, so that the first supporting ring frame 1 and the second supporting ring frame 9 are prevented from moving, the medicine components in the medicine storage cavity 7 are quickly transferred to the blood vessel at a lesion position through the capillary holes 8, the medicine is quickly applied at the initial stage of treatment, the medicine components on the medicine carrying layer 6 are slowly transferred to the inner wall of the blood vessel and absorbed by the inner wall of the blood vessel, and the effect of long-term control is achieved.

The working principle and the beneficial effects of the invention are as follows: when the service life of the magnesium alloy stent exceeds the service life of the magnesium alloy stent, the magnesium alloy stent is gradually degraded and broken, loses mechanical support property and is finally completely absorbed by the body, the renal artery stent can be degraded by arranging the first support ring frame 1, the support strips 2, the axial fixing strips 3 and the second support ring frame 9 which are made of magnesium alloy, has good biocompatibility and strong support force, and can effectively reduce the possibility of occurrence of problems of intimal hyperplasia, restenosis, late thrombosis and the like of blood vessels, the flexible net 11 is propped up by arranging the flexible net 11, the second support ring frame 9 and the circular frame body 12, the flexible net 11 is tightly attached to the inner wall of the opening of the renal artery, the joint of the renal artery blood vessel and the aortic blood vessel is prevented from being narrowed again, the first support ring frame 1 and the second support ring frame 9 do not need to extend into the aortic blood vessel, therefore the normal blood transportation of the aortic blood is not influenced, and by arranging the convex, the contact area between the first supporting ring frame 1 and the second supporting ring frame 9 and the inner wall of the blood vessel is increased, friction is increased, the function of preventing deviation is achieved to a certain degree, and the first limiting ring frame 14 and the second limiting ring frame 17 are arranged, so that the first limiting ring frame 14 and the second limiting ring frame 17 are tightly attached to the inner wall of the aorta, and the movement of the first supporting ring frame 1 and the second supporting ring frame 9 is limited.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.