阅读说明：本技术 3d打印可降解防凝血吻合支架 (3D prints identical support of degradable anti-coagulation blood ) 是由 杨林 孙衎达 徐青峰 韦凯 于 2019-09-26 设计创作，主要内容包括：本发明公开了一种3D打印可降解防凝血吻合支架,包括3D打印制作的支架本体,支架本体呈管状,支架本体内壁喷涂防凝血药物层,支架本体外管口处通过3D打印制作多个自锚件,支架本体两端管口打印有斜坡,支架本体中部通过3D打印制作有环状凸起。该血管吻合支架具有防凝血、与血管内壁平滑过渡,方便操作的特点。(The invention discloses a 3D printing degradable anti-coagulation anastomosis stent which comprises a stent body manufactured by 3D printing, wherein the stent body is tubular, an anti-coagulation medicine layer is sprayed on the inner wall of the stent body, a plurality of self-anchoring parts are manufactured at the outer pipe openings of the stent body through 3D printing, slopes are printed at the pipe openings at two ends of the stent body, and an annular bulge is manufactured in the middle of the stent body through 3D printing. The blood vessel anastomosis stent has the characteristics of blood coagulation prevention, smooth transition with the inner wall of a blood vessel and convenient operation.)

1. The utility model provides a 3D prints identical support of degradable anti-coagulation blood which characterized by: print support body (1) of preparation including 3D, support body (1) be the tubulose, support body (1) inner wall spraying anticoagulant medicine layer (2), the mouth of pipe department is printed a plurality of from anchor (3) through 3D outside support body (1), support body (1) both ends mouth of pipe is printed and is had slope (4), support body (1) middle part is printed and is made through 3D and is had annular arch (5).

2. The 3D printed degradable anti-coagulation anastomosis stent of claim 1, which is characterized in that: the bracket body (1), the self-anchoring piece (3) and the annular bulge (5) are all made of degradable high polymer materials or degradable magnesium alloys.

3. The 3D printed degradable anti-coagulation anastomosis stent of claim 1, which is characterized in that: the stent body (1) is printed into a circular tube shape or a conical tube shape so as to adapt to the inner diameters of blood vessels of a supply area and a receiving area.

4. The 3D printed degradable anti-coagulation anastomosis stent of claim 1, which is characterized in that: the anticoagulant drug layer (2) is sprayed through 3D printing.

5. The 3D printed degradable anti-coagulation anastomosis stent of claim 1, which is characterized in that: the self-anchoring piece (3) is a barb-shaped bulge and is arranged 2-3 mm away from the pipe orifices on two sides.

6. The 3D printed degradable anti-coagulation anastomosis stent of claim 5, which is characterized in that: the barb-shaped bulges are arranged into 3-8 circumferential arrays.

7. The 3D printed degradable anti-coagulation anastomosis stent of claim 1, which is characterized in that: the included angle formed by the slope (4) and the inner wall of the bracket body (1) is 10-15 degrees.

Technical Field

The invention relates to the technical field of blood vessel anastomosis stents, in particular to a 3D printing degradable anti-coagulation anastomosis stent.

Background

Vascular anastomosis is one of basic surgical techniques, and is widely applied to trauma, plastic surgery, tissue repair, organ transplantation, arteriovenous fistulization and ureteral anastomosis.

There are three types of conventional vascular anastomosis: suturing, needle ring, and anastomosis clip. The suture method is the most common blood vessel anastomosis method in clinic at present, but the technical requirement is high, the operation is time-consuming, the needle thread causes platelet aggregation to the full-layer penetrating injury of the blood vessel wall, particularly the injury of the intima of the blood vessel, the intima laceration causes the occurrence rate of aneurysm at an anastomosis port to be high, the suture thread is left in the lumen, on one hand, the inflammation reaction is caused, on the other hand, the knot of the suture thread surrounds the anastomosis port to cause the stiffness and the stenosis of the suture thread, which are important factors causing thrombosis and often cause anastomosis failure; the needle ring method has high requirements on blood vessels, needs to be operated by auxiliary instruments, is not suitable for a stenotic region, has a fixed inner ring diameter, cannot be completely suitable for the inner diameter of anastomotic vessels, exists as an implant for a long time, limits the contraction and relaxation functions of the blood vessels, and does not meet the physiological characteristics of the blood vessels; the anastomosis clip method has been abandoned basically because of the disadvantages of easy loosening, blood leakage after anastomosis surgery and the like.

With the application of 3D printing technology and biodegradable materials in the medical field, the invention provides a vascular anastomosis stent, which solves the problems in the vascular anastomosis process.

Disclosure of Invention

The technical problem to be solved by the invention is as follows: in order to solve the problems existing in the prior art, the 3D printing degradable anti-coagulation anastomosis stent which is capable of preventing coagulation, smoothly transits with the inner wall of a blood vessel and is convenient to operate is provided.

The technical scheme adopted by the invention for solving the technical problems is as follows: the utility model provides a 3D prints degradable and prevents anastomotic support of blood coagulation, includes that 3D prints the support body of preparation, the support body be the tubulose, the spraying of support body inner wall prevents blood coagulation medicine layer, the mouth department of pipe is printed through 3D outside the support body and is made a plurality of anchors certainly, the mouth of pipe is printed and is had the slope at support body both ends, support body middle part is printed through 3D and is made annular arch.

Furthermore, the bracket body, the self-anchoring piece and the annular bulge are all made of degradable high polymer materials or degradable magnesium alloys.

Further, the stent body is printed to be in a circular tube shape or a conical tube shape so as to adapt to the inner diameters of blood vessels of the supply area and the receiving area.

Further, the anticoagulant drug layer is sprayed through 3D printing.

Further, the self-anchoring piece is a barb-shaped bulge and is arranged 2-3 mm away from the pipe orifices on the two sides.

Furthermore, the barb-shaped bulges are arranged into 3-8 circumferential arrays.

Further, the slope and the included angle that the support body inner wall formed be 10 ~ 15.

The 3D printing degradable anti-coagulation anastomosis stent has the beneficial effects that: the stent is made by 3D printing, the material is degradable high molecular material or degradable magnesium alloy, different degradation time materials are selected according to the purpose of the operation, and the stent can be absorbed by the human body after the blood vessel is healed; 3D printing and spraying a layer of anti-coagulation medicine on the inner wall of the bracket to prevent blood from coagulating, manufacturing barb-shaped bulges in pipe orifices on two sides, and sleeving the bracket into a blood vessel to be anastomosed to achieve a self-anchoring state to avoid slipping; the middle part of the bracket is provided with an annular bulge, so that the bracket is convenient to clamp by instruments during operation and is cut off after the blood vessels are anastomosed; the pipe orifices at the two ends can be printed into different diameters so as to adapt to the inner diameters of blood vessels of a supply area and a receiving area; the orifices at two ends are printed into a slope shape so as to be smoothly transited with the inner wall of the blood vessel and avoid forming turbulent flow when blood flows.

Drawings

The invention is further illustrated with reference to the following figures and examples.

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a cross-sectional view of the stent body;

in the figure: 1. the anti-coagulation stent comprises a stent body, 2, an anti-coagulation medicine layer, 3, a self-anchoring part, 4, a slope and 5, an annular bulge.

Detailed Description

The present invention will now be described in further detail with reference to the accompanying drawings. These drawings are simplified schematic views illustrating only the basic structure of the present invention in a schematic manner, and thus show only the constitution related to the present invention.

As shown in fig. 1, 2 the 3D prints degradable and prevents anastomotic support of blood coagulation, print the support body 1 of preparation including 3D, support body 1 is the tubulose, 1 inner wall of support body prints spraying anticoagulant medicine thing layer 2 through 3D, 1 outer mouth of pipe department of support body prints through 3D and makes a plurality ofly from anchor 3, it is protruding for barb form from anchor 3, and set up in 2 ~ 3mm departments apart from the mouth of pipe of both sides, barb form protruding setting up to 3 ~ 8 of circumference array, 1 both ends mouth of pipe of support body is printed and is had slope 4, the contained angle that slope 4 and 1 inner wall of support body formed is 10 ~ 15, 1 middle part of support body prints the preparation through 3D and has annular protrusion 5.

The bracket body 1, the self-anchoring piece 3 and the annular bulge 5 are all made of degradable high polymer materials or degradable magnesium alloys.

The stent body 1 can be printed into a circular tube shape or a conical tube shape to adapt to the inner diameters of blood vessels of a supply area and a receiving area.

The stent is manufactured by 3D printing, the material is degradable high polymer material or degradable magnesium alloy, different degradation time materials are selected according to the purpose of the operation, and the stent can be absorbed by the human body after the blood vessel is healed; 3D printing and spraying a layer of anti-coagulation medicine on the inner wall of the bracket to prevent blood from coagulating, manufacturing barb-shaped bulges in pipe orifices on two sides, and sleeving the bracket into a blood vessel to be anastomosed to achieve a self-anchoring state to avoid slipping; the middle part of the bracket is provided with an annular bulge, so that the bracket is convenient to clamp by instruments during operation and is cut off after the blood vessels are anastomosed; the pipe orifices at the two ends can be printed into different diameters so as to adapt to the inner diameters of blood vessels of a supply area and a receiving area; the orifices at two ends are printed into a slope shape so as to be smoothly transited with the inner wall of the blood vessel and avoid forming turbulent flow when blood flows.

In light of the foregoing description of the preferred embodiment of the present invention, many modifications and variations will be apparent to those skilled in the art without departing from the spirit and scope of the invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.