阅读说明：本技术 用于在蛋白a色谱法期间增强杂质去除的方法 (Methods for enhanced impurity removal during protein a chromatography ) 是由 C·A·贝吉 于 2018-12-20 设计创作，主要内容包括：本文提供涉及经由蛋白A色谱法纯化包含Fc区的多肽(例如,抗体)的方法；涉及在蛋白A色谱法期间使用包含苯甲酸盐和/或苯甲醇的洗涤溶液的方法；以及在蛋白A色谱法之前使用苯甲酸钠调节收获物的方法。(Provided herein are methods involving purification of polypeptides (e.g., antibodies) comprising an Fc region via protein a chromatography; methods involving the use of wash solutions comprising benzoate and/or benzyl alcohol during protein a chromatography; and a method of conditioning the harvest using sodium benzoate prior to protein a chromatography.)