阅读说明：本技术 一种芹菜素的半合成方法 (Semi-synthesis method of apigenin ) 是由 张琦 郭涛 孙绿华 于 2020-06-19 设计创作，主要内容包括：一种芹菜素的半合成方法,包括：以二甲基亚砜为溶剂,将柚皮素与碘在100-120℃温度下进行反应；向反应液中加入保险粉或保原粉以及体积分数25%-50%的乙醇水溶液,在碱性环境下,于70-90℃温度下反应；将反应液趁热过滤,收集滤液,调节温度为30-40℃、pH值为6-7,加入体积分数50%-80%的乙醇水溶液,待晶体析出后过滤,收集滤饼,即得芹菜素产品。该方法反应条件温和、易于控制、步骤简单、操作方便、耗时短、成本低、收率高,且对环境无污染。(A semi-synthesis method of apigenin comprises the following steps: reacting naringenin and iodine at the temperature of 100-120 ℃ by using dimethyl sulfoxide as a solvent; adding sodium hydrosulfite or preservative powder and 25-50% of ethanol aqueous solution by volume fraction into the reaction solution, and reacting at 70-90 ℃ in an alkaline environment; filtering the reaction solution while the reaction solution is hot, collecting filtrate, adjusting the temperature to be 30-40 ℃ and the pH value to be 6-7, adding 50-80% ethanol water solution by volume fraction, filtering after crystals are separated out, collecting filter cakes, and obtaining the apigenin product. The method has the advantages of mild reaction conditions, easy control, simple steps, convenient operation, short time consumption, low cost, high yield and no pollution to the environment.)