阅读说明：本技术 可伸展保持架 (Extensible cage ) 是由 C.恩斯特龙 于 2018-05-04 设计创作，主要内容包括：本发明公开了一种椎间植入物,该椎间植入物在塌缩构型和伸展构型之间迭代,该椎间植入物包括第一板和第二板,该第一板和第二板沿着第一方向彼此间隔开并且限定沿着第一方向背向彼此的骨接触表面。伸展组件相对于第一方向定位在板之间并且包括第一支撑楔形件,该第一支撑楔形件支撑第一板并限定第一坡道；以及第二支撑楔形件,该第二支撑楔形件支撑第二板并限定第二坡道和第三坡道。伸展组件包括限定第四坡道的伸展楔形件。第一坡道、第二坡道、第三坡道和第四坡道各自相对于第二方向倾斜,该第二方向基本上垂直于第一方向。第一支撑楔形件和第二支撑楔形件中的至少一个能够沿着相应的被支撑的第一板或第二板滑动。植入物包括致动器,该致动器被构造为向伸展楔形件施加驱动力,以便致使1)第四坡道沿着第三坡道行进,以便沿着第一方向增加骨接触表面之间的距离,并且2)第二坡道沿着第一坡道行进,从而进一步增加所述距离,从而将植入物从塌缩构型迭代到伸展构型。(An intervertebral implant that iterates between a collapsed configuration and an expanded configuration includes first and second plates that are spaced apart from one another along a first direction and define bone contacting surfaces that face away from one another along the first direction. A spreading assembly positioned between the plates relative to the first direction and including a first support wedge supporting the first plate and defining a first ramp; and a second supporting wedge supporting the second plate and defining a second ramp and a third ramp. The extension assembly includes an extension wedge defining a fourth ramp. The first ramp, the second ramp, the third ramp, and the fourth ramp are each inclined relative to a second direction that is substantially perpendicular to the first direction. At least one of the first and second support wedges is slidable along the respective supported first or second plate. The implant includes an actuator configured to apply a driving force to the extension wedge to cause 1) the fourth ramp to travel along the third ramp to increase a distance between the bone contacting surfaces in the first direction, and 2) the second ramp to travel along the first ramp to further increase the distance to iterate the implant from the collapsed configuration to the extended configuration.)

1. An intervertebral implant configured to iterate between a collapsed configuration and an extended configuration, the implant comprising:

a first plate and a second plate spaced apart from each other along a first direction, the first plate defining a first bone contacting surface, the second plate defining a second bone contacting surface facing away from the first bone contacting surface along the first direction;

a spreader assembly disposed between the first plate and the second plate relative to the first direction, the spreader assembly comprising:

a first support wedge supporting the first plate, the support wedge defining a first ramp;

a second support wedge supporting the second plate, the second support wedge defining a second ramp and a third ramp; and

an expanding wedge defining a fourth ramp,

wherein each of the first, second, third and fourth ramps is inclined relative to a second direction substantially perpendicular to the first direction, and at least one of the first and second support wedges is slidable along the respective supported first or second plate; and

an actuator configured to apply a driving force to the extension wedge so as to cause 1) the fourth ramp to travel along the third ramp so as to increase a distance between the first and second bone contacting surfaces in the first direction, and 2) the second ramp to travel along the first ramp to further increase the distance, thereby iterating the implant from the collapsed configuration to the extended configuration.

2. The implant of claim 1, wherein the distance is increased by a factor of at least 2.0 between the collapsed configuration and the extended configuration.

3. The implant of claim 1, wherein each of the first, second, third, and fourth ramps is inclined at an inclination angle in a range of about 10 degrees and about 60 degrees.

4. The implant of claim 3, wherein the spreading wedge defines an additional ramp configured to travel along the first ramp in response to the driving force, and the additional ramp is inclined at an angle in a range of about 20 degrees and about 50 degrees.

5. The implant of claim 1, wherein:

when the implant is in the collapsed configuration, the entire first support wedge is spaced apart from the entire extension wedge relative to the second direction, and at least a portion of the second support wedge is disposed between the first support wedge and the extension wedge relative to the second direction; and is

When the implant is in the expanded configuration, the first support wedge is located entirely below the expansion wedge relative to the first direction, and the entire second support wedge is spaced apart from the entire first support wedge relative to the first direction.

6. The implant of claim 5, wherein the first plate defines a first channel elongated along the second direction, the second plate defines a second channel elongated along the second direction, the first and second channels open toward and overlap one another so as to define a compartment, and each of the wedges is received within the compartment when the implant is in the collapsed configuration.

7. The implant of claim 6, wherein:

the first channel defines a first base surface extending along the second direction and a third direction, the third direction being perpendicular to the first direction and the second direction;

the second channel defines a second base surface extending along the second and third directions, and the first and second base surfaces face each other;

the second support wedge defines a wedge base surface configured to slide along the second base surface during extension of the implant between the collapsed configuration and the extended configuration, and

the expanding wedge defines another wedge base surface configured to travel along the first base surface during expansion of the implant.

8. The implant of claim 7, wherein the expansion wedge further defines an additional ramp that is inclined relative to the second direction, and the implant is configured such that during a first expansion phase of the implant:

said additional ramp being distal from said first ramp relative to said second direction while said second ramp travels along said first ramp, and;

the fourth ramp travels along the third ramp; and is

The other wedge base surface travels along the first base surface.

9. The implant of claim 8, wherein the implant is configured such that, in a second expansion phase of the implant, 1) the additional ramp travels along the first ramp and 2) the second ramp is distal from the first ramp.

10. The implant of claim 1, wherein the actuator is rotatable about an axis oriented along the second direction and drives the expansion wedge to translate along the second direction as the fourth ramp travels along the third ramp.

11. The implant of claim 1, wherein the actuator is threadably coupled to the extension wedge such that rotation of the actuator about the axis causes the extension wedge to translate along the actuator threads.

12. The implant of claim 1, wherein:

the extension assembly is a first extension assembly; and is

The implant further includes a second extension assembly disposed between the first plate and the second plate relative to the first direction, the second extension assembly being spaced apart from the first extension assembly along the second direction, the second extension assembly including:

a third supporting wedge supporting the first plate, the third supporting wedge defining a fifth ramp;

a fourth supporting wedge supporting the second plate, the second supporting wedge defining a sixth ramp and a seventh ramp; and

a second spreading wedge defining an eighth ramp,

wherein each of the fifth ramp, the sixth ramp, the seventh ramp, and the eighth ramp is inclined relative to the second direction, and at least one of the third support wedge and the fourth support wedge is slidable along the respective supported first plate or second plate, and

the actuator is configured to apply a second driving force to the second extending wedge to cause 1) the eighth ramp to travel along the seventh ramp to collectively increase the distance between the first and second plates in the first direction as the fourth ramp travels along the third ramp, and 2) the sixth ramp to travel along the fifth ramp to collectively further increase the distance between the first and second plates in the first direction as the second ramp travels along the first ramp to iterate the implant from the collapsed configuration to the extended configuration.

13. The implant of claim 1, wherein the expanded configuration is a first expanded configuration, the expansion assembly is a first expansion assembly, the distance is a first distance, and the implant further comprises:

a first side and a second side, the second side being spaced apart from the first side along a third direction, the third direction being substantially perpendicular to the first direction and the second direction, wherein the first distance is measurable at the first side of the implant;

a second spreader assembly disposed between the first plate and the second plate relative to the first direction, the second spreader assembly spaced apart from the first spreader assembly along the third direction, the second spreader assembly comprising:

a third supporting wedge supporting the first plate, the third supporting wedge defining a fifth ramp;

a fourth supporting wedge supporting the second plate, the second supporting wedge defining a sixth ramp and a seventh ramp; and

a second spreading wedge defining an eighth ramp,

wherein each of the fifth ramp, the sixth ramp, the seventh ramp, and the eighth ramp is inclined relative to the second direction and at least one of the third and fourth supporting wedges is slidable along the respective plate supported by the one of the third and fourth supporting wedges; and

a second actuator configured to apply a second driving force to the second expanding wedge, to cause 1) the eighth ramp to travel along the seventh ramp to increase a second distance between the first plate and the second plate in the first direction, wherein the second distance is measurable at the second side, and 2) the sixth ramp travels along the fifth ramp, to further increase the second distance between the first and second plates along the first direction to iterate the implant from the collapsed configuration to the second expanded configuration, wherein, in the second extended configuration, the second distance is different than the first distance such that one of the first and second panels is inclined relative to the other of the first and second panels.

14. An implant for lateral insertion into an intervertebral space, the implant comprising:

an extension mechanism disposed between a first end plate and a second end plate relative to a vertical direction, the first end plate defining a first bone contacting surface, the second end plate defining a second bone contacting surface facing away from the first bone contacting surface along the vertical direction, the extension mechanism comprising:

a front actuation assembly disposed along a first axis; and

a posterior actuation assembly disposed along a second axis, the first and second axes each oriented along a longitudinal direction substantially perpendicular to the vertical direction, the first and second axes spaced apart from one another along a lateral direction substantially perpendicular to the vertical and longitudinal directions, wherein a first distance between the first and second bone contact surfaces along the vertical direction intersects the first axis and a second distance between the first and second bone contact surfaces along the vertical direction intersects the second axis, the anterior and posterior actuation assemblies each comprising:

a first support wedge supporting the first end plate;

a second support wedge supporting the second end plate, the second support wedge being slidable relative to the first support wedge; and

an expanding wedge slidable relative to the second support wedge; and

a drive shaft coupled to the expanding wedge, the drive shaft being rotatable about the respective first or second axis so as to cause 1) the expanding wedge to travel along the second support wedge and 2) the second support wedge to travel along the first support wedge, thereby changing the respective first or second distance;

wherein the drive shafts of the front and rear actuating assemblies are rotatable independently of each other to provide a difference between the first and second distances.

15. The implant of claim 14, wherein each expansion wedge includes a first member and a second member, the first member being rotatable relative to the second member about the respective first or second axis, and the first member being configured to travel along the respective second support wedge in response to rotation of the respective drive shaft, and the second member being configured to travel along the respective first support wedge in response to rotation of the respective drive shaft.

16. The implant of claim 15, wherein:

each end plate defining a front guide feature and a rear guide feature, each of the front and rear guide features extending along the longitudinal direction,

each second support wedge includes a guide element configured to travel along the respective leading or trailing guide feature of the second end plate; and is

The second member of each spreading wedge includes a guide element configured to travel along the respective front or rear guide feature of the first end plate.

17. The implant of claim 16, wherein each second support wedge further comprises a guide feature, and the first member of each expansion wedge defines a guide element configured to travel within the guide feature of the respective second support wedge.

18. The implant of claim 17, wherein each first support wedge defines a guide feature, and the guide element of the respective second member is further configured to travel along the guide feature of the respective first support wedge.

19. The implant of claim 18, wherein each of the guide features is a guide slot and each of the guide elements is a guide projection configured to extend within and travel along the associated guide slot.

20. The implant of claim 19, wherein:

the guide slots of the second end plate and the respective guide protrusions of the second support wedges being cooperatively shaped to rotationally interlock the second end plate to each of the second support wedges with respect to rotation about the respective first or second axis; and is

The guide slots of the second supporting wedge and the respective guide protrusions of the first member are cooperatively shaped to rotationally interlock the second supporting wedge to the respective first member with respect to rotation about the respective first or second axis.

21. The implant of claim 20,

each first support wedge is fixed to the first end plate relative to rotation about the respective first or second axis;

the guide projection of each second member and the respective guide slot of the first end plate are cooperatively shaped to rotationally interlock the first end plate to the associated second member as the guide projection of the associated second member extends within the respective guide slot; and is

The guide projection of each second member and the guide slot of the respective first support wedge are cooperatively shaped to rotationally interlock each first support wedge to the associated first member when the guide projection of the associated first member extends within the guide slot of the associated first support wedge.

Technical Field

The present invention relates to expandable intervertebral implants, and in particular, to implants having a pair of endplates, at least one of which is independently expandable and rotatable relative to the other, and related methods.

Background

If the disc degenerates, it is often desirable to remove the disc. Spinal fusion procedures can be used to treat such conditions and involve replacement of the degenerated intervertebral disc with a device, such as a cage or other spacer, that restores the height of the intervertebral space and allows bone growth through the device to fuse the adjacent vertebrae. Spinal fusion attempts to restore normal spinal alignment, stabilize spinal segments for proper fusion, create an optimal fusion environment, and allow early active activity by minimizing damage to spinal vasculature, dura mater, and neurons. When spinal fusion meets these goals, healing is accelerated and patient function, comfort and mobility are improved. Spacer devices that compact into the intervertebral space and allow bone growth from the adjacent vertebral bodies through the upper and lower surfaces of the implant are known in the art. However, there remains a need for a device that minimizes the invasiveness of the procedure, yet stabilizes the spinal segment and creates an optimal space for spinal fusion.

Disclosure of Invention

According to one embodiment of the present disclosure, an intervertebral implant configured to iterate between a collapsed configuration and an extended configuration includes first and second plates spaced apart from one another along a first direction. The first plate defines a first bone contacting surface and the second plate defines a second bone contacting surface facing away from the first bone contacting surface along the first direction. The implant includes a spreading assembly disposed between the first plate and the second plate relative to the first direction. The extension assembly includes a first support wedge supporting the first plate and defining a first ramp; and a second supporting wedge supporting the second plate and defining a second ramp and a third ramp. The spreading assembly includes a spreading wedge defining a fourth ramp, wherein each of the first, second, third, and fourth ramps are inclined relative to a second direction that is substantially perpendicular to the first direction. At least one of the first and second support wedges is slidable along the respective supported first or second plate. The implant includes an actuator configured to apply a driving force to the extension wedge to cause 1) the fourth ramp to travel along the third ramp to increase a distance between the first bone contacting surface and the second bone contacting surface in the first direction, and 2) the second ramp to travel along the first ramp to further increase the distance to iterate the implant from the collapsed configuration to the extended configuration.

According to another embodiment of the present disclosure, an implant for lateral insertion into an intervertebral space includes an extension mechanism disposed between a first endplate and a second endplate with respect to a vertical direction. The first end plate defines a first bone contacting surface and the second end plate defines a second bone contacting surface facing away from the first bone contacting surface in a vertical direction. The extension mechanism includes a front actuation assembly disposed along a first axis and a rear actuation assembly disposed along a second axis. The first axis and the second axis are each oriented along a longitudinal direction substantially perpendicular to the vertical direction. The first axis and the second axis are spaced apart from each other along a transverse direction substantially perpendicular to the vertical direction and the longitudinal direction. A first distance between the first and second bone contacting surfaces along the vertical direction intersects the first axis and a second distance between the first and second bone contacting surfaces along the vertical direction intersects the second axis. The front and rear actuating assemblies each include a first support wedge that supports the first end plate; and a second support wedge supporting the second end plate and slidable relative to the first support wedge. The actuation assemblies each further comprise an expanding wedge slidable relative to the second supporting wedge; and a drive shaft coupled to the expanding wedge and rotatable about the respective first or second axis to cause 1) the expanding wedge to travel along the second support wedge and 2) the second support wedge to travel along the first support wedge to change the respective first or second distance. The drive shafts of the front and rear actuating assemblies are rotatable independently of each other to provide a difference between the first and second distances.

Drawings

The foregoing summary, as well as the following detailed description of illustrative embodiments of the intervertebral implant of the present application, will be better understood when read in conjunction with the appended drawings. For the purpose of illustrating the expandable intervertebral implant of the present application, there is shown in the drawings exemplary embodiments. It should be understood, however, that the application is not limited to the precise arrangements and instrumentalities shown. In the drawings:

fig. 1 is an end view of an implant positioned between adjacent vertebral bodies with the implant in a collapsed configuration according to a first exemplary embodiment of the present disclosure;

FIG. 2 is a perspective view of the implant of FIG. 1 shown in a collapsed configuration;

FIG. 3 is an end view of the implant of FIG. 1 shown in a collapsed configuration;

FIG. 4 is a longitudinal cross-sectional view of the implant of FIG. 1 shown in a collapsed configuration;

FIG. 5 is a partially exploded perspective view of the implant of FIG. 1 with the bone plates of the implant separated in a manner showing the internal expansion mechanism of the implant in a collapsed configuration;

FIG. 6 is an exploded view of the implant of FIG. 1;

FIG. 7 is an enlarged view of an end portion of one of the bone plates shown in FIG. 6;

FIG. 8 is an opposite perspective view of an end portion of another bone plate shown in FIG. 6;

FIG. 9 is a longitudinal side view of the actuating member of the extension mechanism shown in FIGS. 5 and 6;

FIG. 10 is a perspective view of a first spreading wedge of the spreading assembly shown in FIGS. 5 and 6;

FIG. 11 is another perspective view of the first spreading wedge of FIG. 10;

FIG. 12 is a side view of the first spreading wedge of FIG. 10;

figure 13 is a perspective view of a variant of the first spreading wedge shown in figures 10 to 12;

FIG. 14 is another perspective view of a variation of the first spreading wedge of FIG. 13;

FIG. 15 is a side view of a variation of the first spreading wedge of FIG. 13;

FIG. 16 is a perspective view of a second spreading wedge of the spreading assembly shown in FIGS. 5 and 6;

FIG. 17 is another perspective view of the second spreading wedge of FIG. 16;

FIG. 18 is a side elevational view of the second spreading wedge of FIG. 16;

FIG. 19 is a perspective view of a third spreading wedge of the spreading assembly shown in FIGS. 5 and 6;

FIG. 20 is another perspective view of the third spreading wedge of FIG. 19;

FIG. 21 is a side view of the third spreading wedge of FIG. 19;

FIG. 22 is a perspective view of a fourth spreading wedge of the spreading assembly shown in FIGS. 5 and 6;

FIG. 23 is another perspective view of the fourth spreading wedge of FIG. 22;

FIG. 24 is a side elevational view of the fourth spreading wedge of FIG. 22;

FIG. 25 is a front end view of the fourth spreading wedge of FIG. 22;

FIG. 26 is a side partial cross-sectional view of the first wedge member and the fourth wedge member during a first stage of spreading of the spreading assembly shown in FIGS. 5 and 6;

FIG. 27 is a side partial cross-sectional view of the first wedge member and fourth wedge member of FIG. 26 between a first stage of extension and a second stage of extension of the extension assembly;

FIG. 28 is a side partial cross-sectional view of the first wedge-shaped member and the fourth wedge-shaped member during a second stage of extension of the extension assembly;

fig. 29 is a perspective view of an inner end of the expansion assembly of fig. 5 and 6, with the expansion assembly shown in an expanded and lordotic configuration;

fig. 30 is a side view of the actuation assembly shown in fig. 5 and 6, with the proximal extension assembly shown in a collapsed configuration and the distal extension assembly shown in a fully extended configuration for comparison;

FIG. 31 is an enlarged view of the longitudinal cross-sectional view of FIG. 4, showing the implant in a collapsed configuration;

FIG. 32 is a perspective view of the implant of FIG. 1 in a partially expanded configuration;

FIG. 33 is an end view of the implant shown in FIG. 32;

FIG. 34 is a longitudinal cross-sectional view of the implant illustrated in FIGS. 32 and 33, as taken along section line 34-34 of FIG. 33;

FIG. 35 is a longitudinal cross-sectional view of the implant of FIG. 1 shown in a fully extended configuration;

FIG. 36 is a perspective view of the implant shown in FIG. 35;

FIG. 37 is an end view of the implant shown in FIG. 36;

fig. 38 is a perspective view of the implant of fig. 1 shown in a partially expanded, lordotic configuration;

FIG. 39 is a perspective view of the implant of FIG. 38, shown with the bone plate removed for illustrative purposes;

FIG. 40 is an end view of the implant of FIG. 38;

FIG. 41 is an end view of a pair of wedge members of the actuation assembly shown in FIGS. 5 and 6, illustrating rotation of one of the wedge members relative to the other;

fig. 42 is a perspective view of an implant in a collapsed configuration according to a second exemplary embodiment of the present disclosure;

FIG. 43 is another perspective view of the implant of FIG. 42 showing the bone plates of the implant separated in a manner showing the internal extension mechanism of the implant in a collapsed configuration, further wherein the top one of the bone plates is deployed in a book-like fashion showing the inner faces of the bone plates;

FIG. 44 is a perspective view of a pair of wedge members of the extension mechanism of FIG. 43 positioned along a drive shaft of the extension mechanism;

FIG. 45 is another perspective view of the wedge members of FIG. 44, showing one of the wedge members rotating relative to the other wedge member about the drive shaft;

FIG. 46 is an exploded perspective view of the wedge member of FIG. 44;

FIG. 47 is a perspective view of the implant of FIG. 42 shown in a fully extended configuration with one of the bone plates removed for illustration purposes;

FIG. 48 is an end view of the implant of FIG. 42 in a lordotic configuration;

FIG. 49 is a partially exploded perspective view of the implant of FIG. 48; and is

Fig. 50 is a perspective view of a drive tool configured to extend the implant of fig. 38.

Detailed Description

The disclosure may be understood more readily by reference to the following detailed description taken in conjunction with the accompanying drawings and examples which form a part hereof. It is to be understood that this disclosure is not limited to the specific devices, methods, applications, conditions or parameters described and/or illustrated herein, and that the terminology used herein is for the purpose of describing particular embodiments by way of example only and is not intended to limit the scope of the present disclosure. Furthermore, as used in this specification (including the appended claims), the singular forms "a," "an," and "the" include the plural, and reference to a particular numerical value includes at least that particular value, unless the context clearly dictates otherwise.

The term "plurality" as used herein means more than one. When a range of values is expressed, another embodiment includes from the one particular value and/or to the other particular value. Similarly, when values are expressed as approximations, by use of the antecedent "about," it will be understood that the particular value forms another embodiment. All ranges are inclusive and combinable.

Referring to fig. 1, an upper vertebral body 2 and an adjacent lower vertebral body 4 define an intervertebral space 5 extending between the vertebral bodies 2, 4. The superior vertebral body 2 defines an superior vertebral surface 6 and the adjacent inferior vertebral body 4 defines an inferior vertebral surface 8. The vertebral bodies 2, 4 may be anatomically adjacent or may be the remaining vertebral bodies after removal of the intermediate vertebral bodies from a position between the vertebral bodies 2, 4. The intervertebral space 5 is shown in fig. 1 after a discectomy, whereby disc material has been removed or at least partially removed to prepare the intervertebral space 5 for receiving the expandable intervertebral implant 10. The implant 10 is shown in a collapsed configuration in which the implant 10 may be configured for lateral insertion (i.e., along a medial-lateral trajectory) within the intervertebral space 5.

Once inserted into the intervertebral space 5, the implant 10 may be expanded in a cranio-caudal (i.e., vertical) direction, or otherwise iterated between a collapsed configuration and a fully expanded configuration, to achieve proper height restoration. In addition, one of the lateral sides of the implant 10 may extend vertically to a greater extent than the opposite side to achieve lordosis or kyphosis, as disclosed in greater detail below.

The intervertebral space 5 may be positioned at any location along the spinal column as desired, including at the lumbar, thoracic, and cervical regions of the spinal column. It should be understood that certain features of the implant 10 may be similar to those set forth in U.S. patent publication 2014/0243982a1 issued in the name of Mi ler on 8/28/2014, the entire disclosure of which is incorporated herein by reference.

Certain terminology is used in the following description for convenience only and is not limiting. The words "right", "left", "lower" and "upper" designate directions in the drawings to which reference is made. The words "inner", "inner" and "inner" refer to directions toward the geometric center of the implant 10, while the words "outer", "outer" and "outer" refer to directions away from the geometric center of the implant. The words "anterior," "posterior," "upper," "lower," "medial," "lateral," and related words and/or phrases are used to refer to various positions and orientations within the human body to which reference is made. When these terms are used with respect to the implant 10 or components thereof, they should be understood to refer to the relative position of the implant 10 when implanted in vivo, as shown in fig. 1. The terminology includes the words above listed, derivatives thereof and words of similar import.

Implant 10 is described herein as extending horizontally along longitudinal direction "L" and transverse direction "T" and vertically along vertical direction "V". The longitudinal direction L may be at least substantially perpendicular to each of the transverse direction T and the vertical direction V. The transverse direction T may be at least substantially perpendicular to each of the longitudinal direction L and the vertical direction V. The vertical direction V may be at least substantially perpendicular to each of the longitudinal direction L and the transverse direction T. Unless otherwise indicated herein, the terms "longitudinal," "transverse," and "vertical" are used to describe various implant components and orthogonal components of the implant component axis with reference to the orientation in which the implant 10 is configured to be positioned in the intervertebral space 5; however, such directional terminology may be used consistently with respect to implants regardless of the actual orientation of the implant. Additionally, it should be understood that while the longitudinal direction L and the lateral direction V are shown as extending along and defining a horizontal plane (also referred to herein as a "longitudinal-lateral plane"), and the vertical direction is shown as extending along a vertical plane (such as referred to herein as a "vertical-longitudinal plane" or a "vertical-lateral plane," respectively), planes encompassing the various directions may differ during use. For example, when the implant 10 is inserted into the intervertebral space 5, the vertical direction V generally extends in the superior-inferior (or caudal-cephalad) direction, the longitudinal direction L generally extends in the medial-lateral direction, and the lateral direction L generally extends in the anterior-posterior direction. Thus, the horizontal plane generally lies in the anatomical plane defined by the anterior-posterior direction and the medial-lateral direction. Accordingly, the directional terms "vertical," "longitudinal," "lateral," and "horizontal" and such terms may be used to describe the implant 10 and its components, shown for clarity and explanation purposes only. In view of the foregoing, the terms "expand" and "extend" when used with reference to implant 10 refer to extension along vertical direction V.

Referring now to fig. 2, an implant 10 according to a first embodiment may define a proximal end 12 and a distal end 14 spaced apart from each other along a longitudinal direction L. In particular, the distal end 14 may be spaced from the proximal end 12 in a distal direction, and the proximal end 12 may be spaced from the distal end 14 in a proximal direction opposite the distal direction. Thus, as used herein, the term "longitudinal direction L" is bidirectional and is defined by a unidirectional distal direction and an opposite proximal direction. Additionally, the implant 10 may define an anterior side 16 and a posterior side 18 spaced apart from one another along the transverse direction T. In particular, the front side 16 may be spaced apart from the rear side 18 in a forward direction, and the rear side 18 may be spaced apart from the front side 16 in a rear direction opposite the forward direction. Thus, as used herein, the term "lateral direction T" is bidirectional and is defined by a unidirectional forward direction and an opposite rearward direction.

The implant 10 may include a first or lower plate 20 and a second or upper plate 22 spaced apart from each other along a vertical direction V. Lower plate 20 and upper plate 22 may be referred to as "end plates". The lower plate 20 may define a first or lower plate body 24 and the upper plate 22 may define a second or upper plate body 26. Lower plate body 24 may define a first or lower bone contacting surface 28 on an exterior thereof. The superior plate body 26 can define a second or superior bone contacting surface 30 on an exterior thereof, as shown in fig. 3. The lower bone contacting surface 28 and the upper bone contacting surface 30 may face away from each other. In particular, the superior bone contacting surface 30 can face the superior vertebral surface 6 of the superior vertebra 2, while the inferior bone contacting surface 28 can face the inferior vertebral surface 8 of the inferior vertebral body 4. The lower bone contacting surface 28 and the upper bone contacting surface 30 may each be substantially planar; however, in other embodiments, each bone contacting surface 28, 30 may be at least partially convex, for example, and may at least partially define a texture (not shown), such as spikes, ridges, cones, barbs, indentations, or knurls, configured to engage the respective vertebral body 2, 4 when the implant 10 is inserted into the intervertebral space 5.

When the implant 10 is in the collapsed configuration, the lower and upper bone contacting surfaces 28, 30 may be spaced apart from each other along the vertical direction V by a distance D, which by way of non-limiting example is in the range of about 5mm and about 20mm, although other dimensions are also within the scope of the present disclosure. Additionally, when the implant 10 is in the collapsed configuration, both the lower bone contacting surface 28 and the upper bone contacting surface 30 may be parallel to each other relative to the transverse direction T, and thus may have a neutral (i.e., neither lordotic nor kyphotic) collapsed profile. As used herein, the terms "lordosis," "kyphosis," and their corresponding derivatives are used interchangeably, each term referring to any configuration of the implant 10 in which the inferior and superior bone contacting surfaces 28, 30 are angled relative to each other in a vertical transverse plane.

It should be understood that the lower plate body 24 and the upper plate body 26 can overlap one another such that the proximal end 12 and the distal end 14 of the implant 10 can be characterized as the proximal end 12 and the distal end 14 of each plate 20, 22 or plate body 24, 26. Similarly, the anterior side 16 and the posterior side 18 of the implant 10 may also be characterized as the anterior side 16 and the posterior side 18 of each plate 20, 22 or plate body 24, 26.

As shown in fig. 2 and 3, the proximal end 12 of the implant 10 may include a coupling feature, such as a coupling hole 32, for receiving an insertion instrument configured to insert the implant 10 into the intervertebral space. The attachment holes 32 may be collectively defined by the lower plate body 24 and the upper plate body 26. The implant 10 may also define one or more vertical apertures 34 (fig. 2) extending through the lower plate body 24 and the upper plate body 26 along the vertical direction V. The vertical bores 34 may be in communication with each other and with the coupling bores 32, and may be configured to receive bone growth material for fusion with the superior and inferior vertebral bodies 2, 4 after expansion of the implant 10.

With continued reference to fig. 2, the implant 10 may generally define an anterior portion 36 and a posterior portion 38, each elongated along the longitudinal direction L and located on opposite sides of the vertical bore 34 relative to the transverse direction T. The implant 10 may also generally define a distal portion 40 spaced from the vertical bore 34 in a distal direction. The distal end 14 of the implant 10 may also be referred to as the "insertion end" of the implant 10. To facilitate insertion, the upper and lower plate bodies 12, 18 may each define a tapered surface 42 adjacent the distal end 14, wherein each tapered surface 42 is inclined in the distal direction, as shown in fig. 2 and 4.

Referring now to fig. 5 and 6, each of lower plate body 24 and upper plate body 26 may define an interior face 44 opposite respective bone contacting surfaces 28, 30 relative to vertical direction V. Additionally, the inner faces 44 of the lower plate body 24 and the upper plate body 26 may each define one or more internal contact surfaces 46. When implant 10 is in the collapsed configuration, interior contact surface 46 of upper plate body 26 may abut interior contact surface 46 of lower plate body 24. The inner faces 44 of the lower and upper plate bodies 24, 26 may be coupled to, and configured to engage, a spreading mechanism 48 configured to move spreading members (such as wedges 51, 52, 53, 54) relative to one another in a manner that spreads the implant 10 in the vertical direction V, as discussed in more detail below.

The inner face 44 of each plate body 24, 26 may also define a front channel 56 and a rear channel 58, each elongated along the longitudinal direction L. The anterior and posterior channels 56, 58 of each plate 20, 22 may extend in the vertical direction V from its inner contact surface 46 into the respective plate body 24, 26 toward the respective bone contacting surface 28, 30. The anterior channels 56 of the plates 12, 18 may be located in the anterior portion 36 of the implant 10 and the posterior channels 58 of the plates 12, 18 may be located in the posterior portion 38 of the implant 10. The anterior channels 56 of the plates 12, 18 may overlap one another to at least partially define a first or anterior compartment 60 of the implant 10, while the posterior channels 58 of the plates 12, 18 may overlap one another to at least partially define a second or posterior compartment 62 of the implant 10 (fig. 3). The front compartment 60 and the rear compartment 62 may be configured to house components of the extension mechanism 48. Accordingly, the compartments 60, 62 may be referred to as "extended compartments".

As shown more clearly in the enlarged view of fig. 7, the front and rear channels 56, 58 may each extend between opposing front and rear sidewalls 64, 66 spaced apart along the transverse direction T. Each channel 56, 58 may also extend in the vertical direction V from the inner contact surface 46 to a base surface 68 of the channel 56, 58. Thus, the base surface 68 of each channel 56, 58 may be characterized as being vertically recessed within the plate body 24, 26 from the respective interior contact surface 46 toward the respective bone contact surface 28, 30. The base surface 68 of each channel may extend along the longitudinal direction L and the transverse direction T, and may optionally be substantially planar.

Each channel 56, 58 may also include a guide feature, such as a guide channel 70, recessed from the base surface 68 toward the bone contacting surfaces 28, 30. Each channel 70 of the channels 56, 58 may also be referred to as a "plate channel" 70. The plate guide channels 70 may have a geometry configured to guide one or more components of the extension mechanism 48 within the channels 56, 58 along the longitudinal direction L. Optionally, the plate guide channel 70 may also be configured to provide mechanical interference with such components in the vertical direction V toward the interior contact surface 46 of the associated plate 20, 22. In other words, the plate channel 70 may optionally have a geometry such that the plate bodies 24, 26 interlock with the components of the spreading mechanism 48 in a manner that prevents the components from disengaging from the plate channel 70 (and by extension from the channels 56, 58). Accordingly, the plate channel 70 may also be characterized as a retention feature. For example, the plate guide channels 70 may have a dovetail profile in the vertical transverse plane, as shown. However, it should be understood that other profiles and geometries of the plate channel 70 are also within the scope of the present disclosure.

The inner faces 44 of lower plate body 24 and upper plate body 26 may also define one or more coupling features for coupling lower plate body 24 and upper plate body 26 together, particularly in the collapsed configuration. The coupling features of the plate bodies 14, 20 can be configured to nest with one another in a manner that stabilizes the implant 10 at various stages of the overall operation. For example, as shown in fig. 5 and 6, at the distal portion 40 of the lower plate body 24, the inner face 44 may define a first transverse slot 72, a second transverse slot 74 spaced apart from the first transverse slot 72 in the distal direction, and a transverse wall 76 positioned between the first and second transverse slots 72, 74. The transverse wall 76 may extend along the transverse direction T between a front wall end 78 and a rear wall end 80.

As shown in fig. 8, at the distal portion 40 of the upper plate body 26, the inner face 44 may define a first lateral projection 82, and a second lateral projection 84 spaced apart from the first lateral projection 82 in the distal direction. Each of the first and second lateral projections 82, 84 may project from the upper plate body 26 toward the lower plate body 24 beyond its inner contact surface 46. The first and second lateral projections 82, 84 may each extend in the lateral direction T between a front end 86 and a rear end 88, and may extend in the longitudinal direction L between a proximal face 90 and a distal face 92. When implant 10 is in the collapsed configuration, first and second lateral projections 82, 84 of upper plate body 26 may nest within first and second lateral slots 72, 74 of lower plate body 24, respectively (fig. 4). When implant 10 is extended from the collapsed configuration, transverse projections 82, 84 and transverse slots 72, 74 can effectively stabilize the implant and inhibit relative movement between lower plate body 24 and upper plate body 26 along longitudinal direction L.

Referring again to fig. 5 and 6, an extension mechanism 48 may be positioned between lower plate 20 and upper plate 22. In the illustrated embodiment, the extension mechanism 48 may be configured to convert one or more rotational input forces applied by a physician into one or more corresponding linear extension forces along the vertical direction V. Extension mechanism 48 may include one or more actuation assemblies 94, 96, each configured to convert a rotational input force into a linear extension force along vertical direction V. As shown, the extension mechanism 48 may include a first or forward actuation assembly 94 and a second or rearward actuation assembly 96 spaced apart from each other along the transverse direction T. The front actuating assembly 94 may be configured to input a first rotational input force R₁Converted into a plurality of linear stretching forces Z along the vertical direction V₁、Z₂、Z₃、Z₄So as to stretch the anterior portion 36 of the implant 10 in the vertical direction V. Similarly, rear actuating assembly 96 may be configured to input a second rotational input force R₂Converted into a plurality of linear stretching forces Z along the vertical direction V₁、Z₂、Z₃、Z₄To extend the posterior portion 38 of the implant 10 in the vertical direction V.

Anterior actuation assembly 94 and posterior actuation assembly 96 may be actuated to provide uniform or non-uniform extension or contraction of implant 10 in the vertical direction as desired by the physician. For example, either of the actuating assemblies 94, 96 may be driven independently of the other. When independently driven, anterior and posterior actuation assemblies 94 and 96 can extend anterior and posterior portions 36 and 38 of implant 10 in vertical direction V to different extended heights, thereby providing implant 10 with a lordotic profile in intervertebral space 5, as discussed in more detail below. Thus, the implant 10 allows for vertical extension within the intervertebral space and adjustment of the lordotic angle of the implant 10 independently of each other.

Front actuation assembly 94 and rear actuation assembly 96 may be substantially similarly configured; accordingly, the same reference numerals will be used herein with respect to corresponding components and features of the actuation assemblies 94, 96. Each actuation assembly 94, 96 may include an actuator, such as a drive shaft 98, also shown in fig. 9. The drive shaft 98 may define a central axis X extending along the longitudinal direction L₁And may also define a central axis X along the central axis₁A proximal end 100 and a distal end 102 spaced apart from each other.

With continued reference to fig. 9, the drive shaft 98 may include one or more threaded portions 104, 106 configured to transmit one or more linear drive forces F along the longitudinal direction L₁、F₂. For example, the drive shaft 98 may include a first or proximal threaded portion 104 and along a central axis X₁A second or distal threaded portion 106 spaced from the proximal threaded portion 104 in the distal direction. The threads of the proximal threaded portion 104 and the distal threaded portion 106 may have different thread qualities. For example, in the illustrated embodiment, the proximal threaded portion 104 defines a thread pattern oriented in an opposite direction as the distal threaded portion 106. In this manner, the proximal threaded portion 104 may provide a first linear driving force F upon rotation of the drive shaft 98₁The distal threaded portion 106 may provide a second linear driving force F₂And a first linear driving force F₁And a second linear driving force F₂May be reversed with respect to each other.

The drive shaft 98 may include an intermediate portion 108 positioned between the proximal threaded portion 104 and the distal threaded portion 106. The threads of the proximal threaded portion 104 may substantially interface with the threads of the distal threaded portion 106 at the intermediate portion 108And (7) continuing. Thus, the intermediate portion 108 may define a boundary between the threaded portions 104, 106. In the illustrated embodiment, the intermediate portion 108 can be characterized as an inner end of each of the proximal and distal threaded portions 104, 106, while the proximal end 100 of the drive shaft 98 can define an outer end of the proximal threaded portion 104 and the distal end 102 of the drive shaft 98 can define an outer end of the distal threaded portion 106. Further, in the illustrated embodiment, the intermediate portions 108 of the anterior and posterior drive shafts 98 can define a center or midpoint of the implant 10 relative to the longitudinal direction L. Thus, relative to each threaded portion 104, 106 of the drive shaft 98 (and any components located thereon), the outer longitudinal direction L_EExtending from the inner end 108 to the outer ends 100, 102, an inner longitudinal direction L_IExtending from the outer ends 100, 102 to the inner end 108.

The head 110 may be located at the distal end 102 of the drive shaft 98 and may be continuous with the distal threaded portion 106. The head 110 may be integral with the drive shaft 98 or may be a separate component, such as a nut that is threadably coupled to the distal threaded portion 106. The head 110 may define a proximal end 112 and a distal end 114 spaced from the proximal end 112 along the longitudinal direction L. A drive coupling, such as a nut socket 116, may be threaded to the proximal end 100 of the drive shaft 98 and may be continuous with the proximal threaded portion 104. The nut receptacle 116 may define a receptacle aperture 118 extending from a proximal end 120 of the nut receptacle 116 toward a distal end 122 thereof. As shown, the socket apertures 118 may define hexagonal sockets, but other socket configurations may be employed for connection to a driver tool operated by a physician.

Referring again to fig. 5 and 6, each actuating assembly 94, 96 may include one or more extension assemblies 124, 126 (also referred to as "wedge assemblies") extending along the vertical direction V. For example, a first or proximal wedge assembly 124 may be engaged with the proximal threaded portion 104 of the drive shaft 98 and a second or distal wedge assembly 126 may be engaged with the distal threaded portion 106 of the drive shaft 98. In fig. 6, proximal wedge assembly 124 of rear actuating assembly 96 is shown in phantom, and distal wedge assembly 126 of front actuating assembly 94 is shown in phantom. Proximal wedge assembly 124 and distal wedge assembly 126 may be characterized as subassemblies of respective forward and rearward actuation assemblies 94 and 96. Additionally, within each actuation assembly 94, 96, the proximal and distal wedge assemblies 124, 126 may optionally be substantially mirror images of each other about a vertical transverse plane positioned at the intermediate portion 108 of the drive shaft 98. In other words, distal wedge assembly 126 may be configured to be virtually identical (or at least substantially similar) to proximal wedge assembly 126, with the primary difference being that distal wedge assembly 126 is inverted relative to longitudinal direction L. Some minor variations in proximal wedge assembly 124 and distal wedge assembly 126 are set forth more fully below.

Each of proximal wedge assembly 124 and distal wedge assembly 126 may include a plurality of spreading members or wedges 51, 52, 53, 54 that are movable relative to one another to increase their common height in vertical direction V. For example, the spreading member may include a first wedge-shaped member 51, a second wedge-shaped member 52, a third wedge-shaped member 53, and a fourth wedge-shaped member 54. One or more of the wedges 51, 52, 53, 54 may engage a corresponding threaded portion 104, 106 of the drive shaft 98.

Referring to fig. 4, when implant 10 is in the collapsed configuration, first wedge member 51 may be positioned adjacent the outer ends of respective threaded portions 104, 106 of drive shaft 98; the second wedge-shaped piece 52 may be in the inner longitudinal direction L_ISpaced from first wedge-shaped member 51; the third wedge 53 may be in the inner longitudinal direction L_ISpaced from the second wedge 52; and the fourth wedge-shaped element 54 may be in the inner longitudinal direction L_ISpaced from the third wedge 53. Thus, first wedge 51 may be characterized as an "outermost" wedge, while fourth wedge 54 may be characterized as an "innermost" wedge, although other configurations are possible. Additionally, wedges 51, 52, 53, 54 may define a geometry that provides telescopic movement in longitudinal direction L and vertical direction V for each wedge assembly 124, 126. In other words, wedges 51, 52, 53, 54 may be shaped such that when wedges 51, 52, 53, 54 engage one another, their collective height may increase while their collective length decreases, and vice versa, as set forth in more detail below.

Now refer to10-12, the first wedge-shaped member 51 may have a first wedge-shaped member body 128 defining an inner end 130 and an outer end 132 spaced from the inner end 130 along the longitudinal direction L. The first wedge-shaped body 128 may also define a front side surface 134 and a rear side surface 136 spaced apart from each other along the transverse direction T. The outer end 132 of the first wedge body 128 may define an outer face 138 extending in the vertical direction V between an upward apex 140 and a bottom or base surface 142 of the body 128. The outer face 138 may be substantially planar, but other geometries are within the scope of the present disclosure. Outer face 138 may be configured to limit or prevent first wedge body 128 from following outer longitudinal direction L during operation of implant 10 within a patient_EAdjacent to another component of the implant 10. For example, by way of non-limiting example, in the proximal wedge assembly 124, an outer face 138 of the first wedge 51 may be configured to abut the distal end 122 of the nut receptacle 116.

An upward apex 140 may be located at the outer end 132 of the first wedge body 128. The base surface 142 of the first wedge body 128 may be configured to engage the base surface 68 of the respective front or rear channel 56, 58 of the lower plate body 24. At least a portion of the base surface 142 of the first wedge body 128 may be substantially planar and may be configured to translate at least partially across the bottom surface 68 of the respective channel 56, 58, e.g., at least during assembly of the implant 10. In other embodiments, once in place within the respective channels 56, 58, the first wedge 51 may be secured to the lower plate body 24, such as by welding, brazing, adhesives, or mechanical fasteners. In further embodiments, first wedge 51 may be integral with lower plate body 24. Because first wedge 51 may be characterized as "supporting" lower plate body 24, first wedge 51 may be referred to herein as a "support member" or "supporting wedge".

In the illustrated embodiment, first wedge 51 may also include a first or lower guide element, such as guide protrusion 144, configured to translate within plate guide channel 70 of associated channel 56, 58, for example, during assembly of implant 10. The guide protrusion 144 may extend from the base surface 142 of the first guide body 128.Bottom surface 146 of guide projection 144 may define the bottommost portion of first wedge 51 and the respective wedge assembly 124, 126. The guide protrusions 144 may have a geometry configured to guide movement of the first wedge-shaped body 128 within the respective channel 56, 58 in the longitudinal direction L. Additionally, the guide protrusions 144 of the first wedge body 128 and the corresponding guide channels 70 of the lower plate body 24 may be cooperatively shaped such that the first wedge body 128 interlocks with the lower plate body 24 in a manner that prevents the first wedge body 128 and the lower plate body 24 from disengaging in the vertical direction V. For example, as shown, the guide protrusions 144 and the plate guide slots 70 may have corresponding dovetail profiles in the vertical transverse plane, although other geometries are within the scope of the present disclosure. In this manner, first wedge-shaped member 51 is longitudinally movable within respective channels 56, 58 of lower plate body 24, but is substantially vertically immovable. Accordingly, guide projection 144 may also be characterized as a retention feature of first wedge-shaped member 51. In addition, the profile of guide protrusions 144 and plate guide slots 70 may allow first wedge 51 and lower plate body 24 to rotationally interlock with one another such that, for example, first wedge 51 and lower plate body 24 may remain about central axis X during extension and optionally lordosis₁The same angular position of (a). In other embodiments, the rotational interlocking of first wedge-shaped member 51 and lower plate body 24 may allow first wedge-shaped member 51 to rotate about central axis X₁Thereby causing the lower plate body 24 to rotate about the central axis X₁Substantially similar degrees of rotation, and vice versa.

The first wedge body 128 may also include an engaging element configured to engage a portion of one or more other wedges (such as the second wedge 52 and the fourth wedge 54) of the respective wedge assembly 124, 126. The engaging element may include a first inclined surface or ramp 148 extending between the inner end 130 of the first wedge body 128 and the upward apex 140. When positioned within respective actuating assemblies 94, 96, first wedge-shaped member 51 may be oriented such that first ramp 148 is in outer longitudinal direction L_EAnd (4) inclining. In the illustrated embodiment, the first ramp 148 may be at a range of about 10 degrees and about 60 degrees relative to the longitudinal direction L (fig. 12)First inclination angle alpha₁And (4) orientation. In other embodiments, the first inclination angle α₁May be in a range of about 20 degrees and about 40 degrees relative to the longitudinal direction L. In further embodiments, the first inclination angle α₁May be in a range of about 25 degrees and about 35 degrees relative to the longitudinal direction L. In additional embodiments, the first inclination angle α₁May be less than 10 degrees or greater than 60 degrees relative to the longitudinal direction L.

First wedge-body 128 may also define a second or upper guide feature, such as guide slot 150, configured to guide relative movement between first wedge-piece 51 and another wedge-piece of the associated wedge-piece assembly 124, 126, such as fourth wedge-piece 54. The guide slot 150 may be recessed from the first ramp 148 into the first wedge-shaped body 128. The channel 150 may extend from a channel opening 152 at the inner end 130 of the first wedge body 128 to the outer face 138 of the first guide body 128 relative to the longitudinal direction L. The guide slot 150 may extend parallel to the first ramp 148 and may have a geometry configured to guide movement of an associated guide element of the fourth wedge 54 therein. Optionally, guide slot 150 may also be configured to interlock with an associated guide element in a manner that prevents fourth wedge 54 from disengaging with first wedge 51 at least in a direction orthogonal to first ramp 148. As shown, the guide slot 150 may have a dovetail profile in the vertical transverse plane, but other geometries are within the scope of the present disclosure. The guide slot 150 may traverse the entire length of the first ramp 148, as shown, or may optionally traverse less than the entire length. Additionally, the guide slot 150 may divide the first ramp 148 into a front portion 154 and a rear portion 156, which may be characterized as a "rail".

The first wedge body 128 may define a channel 158 that extends through the body 128 along the longitudinal direction L. Channel 158 may be U-shaped, and the portions of first-wedge body 128 on opposite lateral sides of channel 158 may be characterized as a front arm 160 and a rear arm 162 (fig. 10) of first-wedge body 128. The passage 158 may be sized, shaped, and/or otherwise configured to provide space for the respective threaded portions 104, 106 of the drive shaft 98 to extend at least partially through the body 128 (i.e., between the arms 160, 162) without mechanically interfering with the body 128. Thus, the first wedge-shaped body 128 may have a U-shaped profile in a vertical transverse plane. Channel 158 can also intersect guide slot 150 in a manner that effectively divides a portion of guide slot 150 into a front slot 164 and a rear slot 166 defined in front arm 160 and rear arm 162, respectively.

Referring now to fig. 13-15, a variation of first wedge-shaped member 51' is shown. In particular, the variant 51' may be used in the rear actuating assembly 96. The variant 51' may be substantially similar to the first wedge-shaped member 51 shown in fig. 10 to 12; accordingly, similar reference numerals may be used, with corresponding features of the modified first wedge-shaped member 51' being indicated with an "apostrophe" designation. The primary difference in the modified first wedge-shaped member 51 'is that the outer face 138' of the first wedge-shaped member body 128 'is a first outer face 138' defined by the laterally outer one of the front and rear arms 160', 162'. Additionally, an opposing (i.e., laterally inner) one of the arms 160', 162' may define a second outer face 139 'that extends from the first outer face 138' in the inner longitudinal direction L_IAnd (4) sinking.

The first outer face 138' of the first wedge member 51' may abut the proximal side 112 of the head 110 and the second outer face 139' may abut the proximal side 90 of the first transverse projection 82 of the upper plate body 26 (fig. 30). Accordingly, the proximal face 90 of the first lateral projection 82 may be referred to as an abutment surface of the upper plate body 26. Such a configuration may increase the stability of the implant 10 at least during expansion, contraction, and/or lordotic angulation of the implant 10. However, in other embodiments, first wedge 51 of distal wedge assembly 126 may actually be the same as first wedge 51 of proximal wedge assembly 124. As with first wedge 51, variation 51' may be characterized as a "support member" or "support wedge" and can be securely fixed to lower plate body 24, optionally by welding, brazing, adhesives, or mechanical fasteners. It should be appreciated that the modified first wedge member 51' of the forward actuating assembly 94 may be a substantial mirror image of its counterpart in the rearward actuating assembly 96 about a vertical longitudinal plane positioned between the actuating assemblies 94, 96.

Referring now to fig. 16-18, the second wedge 52 may have a second wedge body 168 defining an inner end 170 and an outer end 172 spaced from the outer end 172 along the longitudinal direction L. The second wedge body 168 may also define a front side surface 174 and a rear side surface 176 spaced apart from each other along the transverse direction T. Second wedge body 168 may also define an outer face 178 at outer end 172. An outer face 178 of second wedge body 168 may extend in vertical direction V and transverse direction T and may be substantially planar, although other geometries are within the scope of the present disclosure. Second wedge body 168 may also define an upper base surface 180 and an opposing downward apex 182 spaced from upper base surface 180 along vertical direction V. The upper base surface 180 may extend along the longitudinal direction L between the inner end 170 and the outer end 172 of the body 168. Downward vertex 182 may be located between inner end 170 and outer end 172 of second wedge body 168 relative to longitudinal direction L.

The upper base surface 180 may be configured to engage the base surface 68 of the respective front or rear channel 56, 58 of the upper plate body 26. Accordingly, second wedge 52 may be characterized as "supporting" upper plate body 26, and may be referred to herein as a "support member" or "supporting wedge. At least a portion of the upper base surface 180 may be substantially planar and may be configured to translate at least partially across the base surface 68 of the respective channel 56, 58 during expansion of the implant 10. Accordingly, the second wedge-shaped member 52 may also be referred to as a "slider".

Second wedge body 168 may define a third or upper guide element, such as guide protrusion 184, extending from upper base surface 180 along vertical direction V. A top surface 186 of guide projection 184 may define a topmost portion of second wedge-shaped member 52. Top surface 186 may also define the topmost portion of the respective wedge assembly 124, 126. The guide projection 184 may be configured to translate within the guide slot 70 of the associated channel 56, 58 of the upper plate body 26. The guide protrusions 184 of the second wedge body 168 may have designs and functions substantially similar to those of the guide protrusions 144 of the first wedge body 128 set forth above. By way of non-limiting example, the guide protrusions 184 of the second wedge body 168 and the guide slots 70 of the associated channels 56, 58 of the upper plate body 26 may have corresponding dovetail profiles, with the dovetails beingThe contoured profile interlocks the second wedge 52 to the upper plate body 26. In this manner, the guide projections 184 (which may also be characterized as "retention" features) are longitudinally movable within the respective channels 56, 58 of the upper plate body 26, but are substantially vertically immovable. In addition, the profile of guide protrusion 184 and plate guide slot 70 may allow second wedge 52 and upper plate body 26 to rotationally interlock with one another such that, for example, second wedge 52 is about central axis X of drive shaft 98₁Causes the upper plate body 26 to rotate about the central axis X₁Substantially similar degrees of rotation, and vice versa.

The second wedge 52 may include one or more engagement elements configured to engage portions of one or more of the other wedges of the associated wedge assembly 124, 126. By way of non-limiting example, second wedge body 168 may define a second sloped surface or ramp 188 extending from outer face 178 to downward vertex 182, and a third sloped surface or ramp 190 extending from downward vertex 182 to inner end 170 of second wedge body 168. Inner end 170 of second wedge body 168 may define a shared edge between upper base surface 180 and third ramp 190. The second wedge 52 may be oriented in each of the actuating assemblies 94, 96 such that the second ramp 188 is in the outer longitudinal direction L_EInclined and the third ramp 190 is in the outer longitudinal direction L_EDescending (and thus in the inner longitudinal direction L)_ITilt). Second ramp 188 may be configured to engage first ramp 148 of first wedge body 128 during extension of implant 10. Third ramp 190 may be configured to engage a portion of another wedge (such as third wedge 53) of the respective wedge assembly 124, 126.

Second ramp 188 may optionally be substantially parallel to first ramp 148 of first wedge-shaped body 128. The second ramp 188 may be at a second angle of inclination α within a range of about 10 degrees and about 60 degrees relative to the longitudinal direction L (fig. 18)₂And (4) orientation. In other embodiments, the second angle of inclination α₂May be in a range of about 20 degrees and about 40 degrees relative to the longitudinal direction L. In further embodiments, the second angle of inclination α₂May be in a range of about 25 degrees and about 35 degrees with respect to the longitudinal direction LInside the enclosure. In additional embodiments, the second angle of inclination α₂May be less than 10 degrees or greater than 60 degrees relative to the longitudinal direction L.

The third ramp 190 may be at a third inclination angle α in a range of about 10 degrees and about 60 degrees relative to the longitudinal direction L₃And (4) orientation. In other embodiments, the third angle of inclination α₃May be in a range of about 20 degrees and about 40 degrees relative to the longitudinal direction L. In further embodiments, the third inclination angle α₃May be in a range of about 25 degrees and about 35 degrees relative to the longitudinal direction L. In additional embodiments, the third angle of inclination α₃May be less than 10 degrees or greater than 60 degrees relative to the longitudinal direction L.

Second wedge-shaped member 52 may include a fourth guide feature, such as guide slot 192, configured to guide relative movement between second wedge-shaped member 52 and another wedge-shaped member of an associated wedge-shaped member assembly 124, 126, such as third wedge-shaped member 53. Guide channel 192 may be recessed from third ramp 190 into second wedge body 168 and may divide third ramp 190 into a forward portion 194 and a rearward portion 196, which may be characterized as a "rail". The guide slot 192 may extend parallel to the third ramp 190 and may have a geometry configured to guide the movement of and optionally interlock with an associated guide element of the third wedge 53. As shown, the guide slot 192 may have a dovetail profile and may be configured similar to the guide slot 150 of the first wedge-shaped body 128, as set forth above, although other geometries are within the scope of the present disclosure. The guide slot 192 may extend from a guide slot opening 198 at the upper base surface 180 to a stop feature 200 configured to prevent the guide element of the third wedge 53 from following the outer longitudinal direction L_EMoves beyond stop feature 200. The stop feature 200 may be along the inner longitudinal direction L_ISpaced from downward vertex 182. Thus, the guide slot 192 may extend less than the entire length of the third ramp 190.

Second wedge body 168 may define a channel 202 extending therethrough along longitudinal direction L. The channel 202 of the second wedge body 168 may be configured similarly to the first wedge body 128 channel 158 set forth above. Thus, second wedge body 168 may have a U-shaped profile in a vertical transverse plane and may include front and rear arms 204, 206 on opposite transverse sides of channel 202. Additionally, channel 202 may divide second ramp 188 into a forward portion 208 and an aft portion 210, which may be characterized as a "rail". The channel 202 can also intersect the guide slot 192 in a manner that effectively converts a portion of the guide slot 192 into a front slot 212 and a rear slot 214 defined in the front arm 204 and the rear arm 206, respectively.

Referring now to fig. 19-21, the second wedge-shaped piece 53 may have a third wedge-shaped body 216 defining an inner end 218 and an outer end 220 spaced from the inner end 218 along the longitudinal direction L. The third wedge body 216 may also define a front side surface 222 and a rear side surface 224 that are spaced apart from each other along the transverse direction T. The third wedge body 216 may also define an inner face 226 at its inner end 218 and an outer face 228 at its outer end 220. The inner face 226 and the outer face 228 of the third wedge body 216 may each extend along the vertical direction V and the lateral direction T, and may each be substantially planar, although other geometries are within the scope of the present disclosure. The third wedge body 216 may define a central bore axis X along₂An extended central aperture 230. The central bore 230 may be a through bore and the central bore axis X₂May extend along the longitudinal direction L. The central bore 230 may define threads 232 configured to engage at least one of the proximal threaded portion 104 and the distal threaded portion 106 of the drive shaft 98 such that rotation of the drive shaft 98 threadably translates the third wedge 53 along the longitudinal direction L. Thus, the central bore axis X₂Can be aligned with the central axis X₁Are coextensive. The third wedge body 216 may also be configured to surround the central bore axis X₂Rotation, as set forth in more detail below.

Third wedge 53 may include one or more engagement elements configured to engage portions of one or more of the other wedges (such as second wedge 52 and fourth wedge 54) of the associated wedge assembly 124, 126. For example, an inner face 226 of the third wedge 53 may be configured to engage (such as by abutting) a portion of the fourth wedge 54. Additionally, the third wedge body 216 may defineA fourth inclined surface or ramp 234 at the upper side of the body 216. The fourth ramp 234 may extend between the inner face 226 and the outer face 228 along the longitudinal direction L. The fourth ramp 234 may be in the outer longitudinal direction L_EDescending (and thus in the inner longitudinal direction L)_ITilt).

Fourth ramp 234 may be configured to engage third ramp 188 of second wedge body 168, including during extension of implant 10. Fourth ramp 234 may optionally be substantially parallel to third ramp 190 of second wedge body 168. The fourth ramp 234 may be at a fourth inclination angle α in a range of about 10 degrees and about 60 degrees relative to the longitudinal direction L (FIG. 21)₄And (4) orientation. In other embodiments, the fourth angle of inclination α₄May be in a range of about 20 degrees and about 40 degrees relative to the longitudinal direction L. In further embodiments, the fourth angle of inclination α₄May be in a range of about 25 degrees and about 35 degrees relative to the longitudinal direction L. In additional embodiments, the fourth angle of inclination α₄May be less than 10 degrees or greater than 60 degrees relative to the longitudinal direction L.

Third wedge 53 may include a fifth guide element, such as guide protrusion 236, configured to guide movement between third wedge 53 and second wedge 52. For example, guide projection 236 of third wedge 53 may extend vertically from fourth ramp 234 and may be configured to translate within guide slot 192 of second wedge 52. The guide projection 236 may be cooperatively shaped with the guide slot 192 in a manner that prevents the guide projection 236 from exiting the guide slot 192 at least in a direction orthogonal to the third ramp 190. For example, the guide protrusions 236 and the guide slots 192 may have corresponding dovetail profiles in the vertical transverse plane, as shown. In such embodiments, the guide projection 236 may only enter and exit the guide slot 192 through the guide slot opening 198. In addition, the profiles of guide slot 192 and guide projection 236 may also allow second wedge-shaped member 52 and third wedge-shaped member 53 to rotationally interlock with one another such that, for example, third wedge-shaped member 53 surrounds central bore axis X₂Causes the second wedge-shaped member 52 to rotate about the central bore axis X₂Substantially similar degrees of rotation.

Third wedge 53 may have a profile configured to avoid interference between first wedge 51 and third wedge 51The geometry of contact with first wedge-shaped member 51 during relative movement between members 53. For example, the third wedge body 216 may have a rounded underside 238 that is configured to not contact or otherwise directly engage or interfere with the first ramp 148 or the front and rear arms 160, 162 of the first wedge body 128 during translational and rotational movement of the third wedge body 216 over the first wedge body 128. Additionally, the underside 238 may define a fifth inclined surface or ramp 240 at a first angle of inclination α to the first ramp 148₁The substantially parallel fifth inclination angle α 5 is oriented. The fifth ramp 240 may be configured to not contact the first ramp 148. For example, the fifth ramp 240 may include a pair of planar portions 242 positioned on opposite lateral sides of a rounded portion 244. Rounded portions 244 may be configured to extend within guide slots 150 of first wedge body 128 during translational and rotational movement of third wedge body 216 over first wedge body 128 without contacting first ramp 148 or any other portion of first wedge body 128. Additionally, during movement of third wedge body 216 over first wedge body 128, planar portion 242 of fifth ramp 240 may be moved away from first ramp 148 or any other portion of first wedge body 128.

Referring now to fig. 22-25, the fourth wedge-shaped piece 54 may have a fourth wedge-shaped piece body 246 defining an inner end 248 and an outer end 250 spaced from the inner end 248 along the longitudinal direction L. The fourth wedge-shaped body 246 may also define a front side surface 252 and a rear side surface 254 that are spaced apart from each other along the transverse direction T. Fourth wedge-shaped body 246 may also define an inner face 256 at its inner end 248 and an outer face 258 at its outer end 250. Inner face 256 and outer face 258 of fourth wedge-shaped body 246 may each extend along vertical direction V and lateral direction T, and may each be substantially planar, although other geometries are within the scope of the present disclosure. Fourth wedge-shaped body 246 may include a top surface 260 and a bottom surface 262 opposite top surface 260 with respect to vertical direction V. Bottom surface 262 may also be referred to as a "base" surface of fourth wedge-shaped piece 54, and may extend along longitudinal direction L and transverse direction T. Bottom surface 262 may optionally be planar. For example, the fourth wedge-body 246 may be rounded or chamfered between the top surface 260 and the side surfaces 252, 254 to avoid contact or otherwise directly engaging or interfering with the third ramp 190 or any other portion of the second wedge-body 168 during translational and rotational movement of the fourth wedge-body 246 under the second wedge-body 168.

Fourth wedge-shaped body 246 may define a central bore axis X₃An extended central bore 264. The central bore 264 may be a through bore and may extend along the longitudinal direction L. Center bore axis X of fourth wedge-shaped body 246₃About a central axis X of the drive shaft 98₁And with the central bore axis X of the third wedge body 216₂Are coextensive. The central bore 264 of the fourth wedge body 246 may define threads 266 configured to engage the same threads in one of the proximal and distal threaded portions 104, 106 as the threads 232 of the third wedge body 216. In the illustrated embodiment, rotation of the drive shaft 98 may threadably translate the third wedge 53 and the fourth wedge 54 together at the same rate along the longitudinal direction L. However, in other embodiments, third wedge 53 and fourth wedge 54 of each wedge assembly 124, 126 may move along drive shaft 98 at different rates and/or in opposite directions.

Fourth wedge 54 may include one or more engagement elements configured to engage portions of at least one of the other wedges (such as third wedge 53) of the associated wedge assembly 124, 126. For example, an outer face 258 of fourth wedge-shaped body 246 may be characterized as an engagement element, as it may be configured to abut inner face 226 of third wedge-shaped body 216. An outer face 258 of fourth wedge body 54 may optionally be configured to abut inner face 226 of third wedge body 216 in a manner that ensures that third wedge body 216 and fourth wedge body 158 translate at the same rate along respective threaded portions 104, 106 of drive shaft 98. In this manner, the fourth wedge-shaped element 54 may be characterized as effectively being in the outer longitudinal direction L_EThe "pusher" or "pusher member" of the third wedge 53. Additionally, it should be understood that the third wedge shapePieces 53 and fourth wedge 54 may be collectively referred to as an "expanding wedge," with third wedge 53 being referred to as a "first member" or "first portion" of the expanding wedge, and fourth wedge 54 being referred to as a "second member" or "second portion" of the expanding wedge. Additionally, each of the third wedge-shaped member 53 and the fourth wedge-shaped member 54 may be individually referred to as an "extended wedge-shaped member".

Fourth wedge-shaped body 246 may also define a sixth inclined surface or ramp 268 adjacent bottom surface 262 of body 246. Sixth ramp 268 may extend between bottom surface 262 and outer face 256 of fourth wedge-shaped body 246 relative to longitudinal direction L. The sixth ramp 268 may be in the outer longitudinal direction L_EInclined (and thus in the inner longitudinal direction L)_IDown). Sixth ramp 268 may be configured to engage first ramp 148 of first wedge body 128 during extension of implant 10. The sixth ramp 268 may optionally be substantially parallel to the first ramp 148. The sixth ramp 268 may be at a sixth inclination angle α in a range of about 10 degrees and about 60 degrees relative to the longitudinal direction L (FIG. 24)₆And (4) orientation. In other embodiments, the sixth angle of inclination α₆May be in a range of about 20 degrees and about 40 degrees relative to the longitudinal direction L. In further embodiments, the sixth inclination angle α₆May be in a range of about 25 degrees and about 35 degrees relative to the longitudinal direction L. In additional embodiments, the sixth angle of inclination α₆May be less than 10 degrees or greater than 60 degrees relative to the longitudinal direction L.

The fourth wedge 54 may include a sixth guide element, such as a guide protrusion 270, configured to guide movement between the fourth wedge 54 and each of the inner plate 12 and the first wedge 51. A guide tab 270 may extend from each of the bottom surface 262 and the sixth ramp 268. The guide protrusions 270 may be configured such that in one stage of extension of the implant 10, the protrusions 270 may translate within the guide slots 70 of the corresponding channels 68 of the lower plate body 24, and during another stage of extension, the protrusions 270 may translate within the guide slots 150 of the first wedge 51.

Guide protrusion 270 of fourth wedge-shaped body 246 may include one or more portions configured to selectively engage the guide features of lower plate body 24 and the guide features of first wedge-shaped member 51. For example, in the non-limiting example shown in fig. 22-24, the guide projection 270 may include a first portion 271, a second portion 272, a third portion 273, and a fourth portion 274. The first portion 271 may extend from the sixth ramp 268. A fourth portion 274 may extend from the bottom surface 262. The second portion 272 may be located below the first portion 271. The third portion 273 may be generally located below the fourth portion 274. The first portion 271 and the fourth portion 274 may each have a rectangular profile in a vertical transverse plane. The second and third portions 272, 273 can each have a dovetail profile in the vertical transverse plane. On each of front side 252 and rear side 254 of fourth wedge-shaped body 246, edge 276 between first portion 271 and second portion 272 may be parallel to bottom surface 262. Also on each side 252, 254, an edge 278 between the third portion 273 and the fourth portion 274 may be parallel to the sixth ramp 268. The second portion 272 may taper laterally inward from an edge 280 between the second portion 272 and the third portion 273 toward the first portion 271. The third portion 273 may taper laterally inward from an edge 280 between the second portion 272 and the third portion 273 toward the fourth portion 274.

As shown in fig. 26, during the first expansion stage of the implant 10, the second, third and fourth portions 272, 273 and 274 of the guide projection 270 of the fourth wedge member 54 may be positioned within the respective plate guide channel 70 while the first portion 271 is positioned outside of the plate guide channel 70. At the end of the first stage (which may also be considered the beginning of the second expansion stage), as shown in fig. 27, protrusion 270 may be positioned in both plate channel 70 and channel 150 of first wedge-shaped member 51. The geometry of the protrusion 270 allows it to be transferred from the plate channel 70 to the first wedge channel 150 and remain in the first wedge channel 150 during the second stage of extension, as shown in fig. 28. During the second stage, the first, second, and third portions 271, 272, 273 of the guide protrusion 270 may be positioned within the channel 150 of the first wedge member 51, while the fourth portion 274 may be outside of the channel 150.

It should be appreciated that the dovetail profile of the guide projection 270, particularly at the edge 280 between the second and third portions 272, 273, may substantially match the dovetail profile of the channel 70 of each channel 62, 64 and the channel 102 of the first wedge member 51. Second portion 272 of guide protrusion 270 may be configured to allow guide protrusion 270 to transition from channel 70 of lower plate body 24 to channel 150 of first wedge member 51 during the first and second stages. Third portion 273 of guide protrusion 270 may be configured to allow guide protrusion 270 to transfer from channel 150 of first wedge member 51 to channel 70 of lower plate body 24 during an optional reverse expansion process (i.e., during a collapsing or "collapsing" process) of implant 10, as set forth in more detail below.

A third portion 273 of guide projection 270, particularly at an edge 280 between second portion 272 and third portion 273, can be cooperatively shaped with channel 150 of first wedge member 51 in a manner that prevents guide projection 270 from exiting channel 150 at least in a direction orthogonal to first ramp 148 and optionally in any direction other than a direction parallel to first ramp 148. In the embodiment shown, the guide protrusions 270 may enter and exit the channel 150 only at the inner end 130 (through the channel opening 198), or optionally at the outer end 132 of the first wedge body 128.

In addition, the second portion 272 of the guide projection 270, particularly at the edge 280 between the second portion 272 and the third portion 273, can be cooperatively shaped with the guide slot 70 of the respective channel 62, 64 of the lower plate body 24 in a manner that prevents the guide projection 270 from exiting the guide slot 70 at least in a direction orthogonal to the channel base surface 68 and optionally in any direction other than the longitudinal direction L or a direction parallel to the first ramp 148. Additionally, when the guide protrusion 270 is positioned within the plate channel 70 (fig. 26), the profile of the guide protrusion 270 and the plate channel 70 may allow the lower plate body 24 to rotationally interlock with the fourth wedge 54 such that, for example, the fourth wedge 54 and the lower plate body 24 may be rotationally interlocked about the central axis X₁Maintaining the same angular position. Because the first wedge-shaped member 51 can be rotationally interlocked with the lower plate body 24 (fig. 40) and the fourth wedge-shaped member 54 can be rotationally interlocked with the lower plate body 24 or with the first wedge-shaped member 51 (fig. 26-28), the lower plate body 24 can be rotationally interlocked with both the first wedge-shaped member 51 and the fourth wedge-shaped member 54 during all stages of extension.

It should be appreciated that in the illustrated embodiment, second wedge-shaped member 52, third wedge-shaped member 53, and fourth wedge-shaped member 54 of proximal wedge-shaped member assembly 124 may be substantially similar, or even virtually identical, to their corresponding counterparts in distal wedge-shaped member assembly 126. However, in other embodiments, one or more of second wedge-shaped member 52, third wedge-shaped member 53, and fourth wedge-shaped member 54 of proximal wedge-shaped member assembly 124 may be configured differently than their corresponding counterparts in distal wedge-shaped member assembly 126.

Referring now to FIG. 29, distal wedge assembly 126 is shown during the second expansion stage. About the axis X of the drive shaft 98 in the third wedge-shaped element 53 relative to the fourth wedge-shaped element 54₁The profiles of the guide groove 192 of the second wedge-shaped member 52 and the guide projection 236 of the third wedge-shaped member may allow the second wedge-shaped member 52 to rotationally interlock with the third wedge-shaped member 53 when rotated, as set forth above. Additionally, as also set forth above, the profile of guide protrusions 270 of guide slots 150 of first wedge-shaped member 51 and guide protrusions 270 of fourth wedge-shaped member 54 may allow first wedge-shaped member 51 and fourth wedge-shaped member 54 to rotationally interlock with one another when guide protrusions 270 are within guide slots 150, such that, for example, first wedge-shaped member 51 and fourth wedge-shaped member 54 rotate about central axis X₁Maintain the same angular position, or in other embodiments, so that first wedge-shaped member 51 and fourth wedge-shaped member 54 are about central axis X during operation of implant 10₁Rotated by the same extent.

Referring now to FIG. 30, wedges 51, 52, 53, 54 of each wedge assembly 124, 126 may have telescopic mobility in longitudinal direction L and vertical direction V. It should be appreciated that each of forward and rearward actuation assemblies 94, 96, and each of proximal and distal wedge assemblies 124, 126 may also be considered to be in their respective collapsed configurations when implant 10 is in the collapsed configuration. For comparison purposes, fig. 30 depicts proximal wedge assembly 124 in a collapsed configuration, while distal wedge assembly 124 is depicted in a fully extended configuration. Each wedge assembly 124, 126 may define a length measured along longitudinal direction L from an outer face 138 of first wedge 51 to an inner face 256 of fourth wedge 54, and a guide projection along vertical direction V from first wedge 51The height of the bottom surface 146 of the horn 144 as measured from the top surface 186 of the guide projection 184 of the second wedge 122. In the collapsed configuration, each wedge assembly 124, 126 may define a collapsed length L₁And a collapsed height H₁. In the fully extended configuration, each wedge assembly 124, 126 may define a length less than the collapsed length L₁Is extended length L₂And greater than collapse height H₁Is extended to a height H₂. In other words, each wedge assembly 124, 126 may decrease in length as the height increases. By way of non-limiting example, the ratio of extended height H2 to collapsed height H1 may be in the range of about 1.5:1 to 3.5: 1. Thus, the vertical distance D between the bone contacting surfaces 28, 30 (fig. 31) may also increase by a similar margin during extension of the implant 10. For example, by way of non-limiting example, the vertical distance D may increase by a factor in the range of about 1.05 and about 3.0 from the collapsed configuration to the fully extended configuration.

Operation of the implant 10, including expansion and lordosis, will now be discussed with reference to fig. 31-41, starting with the implant in a collapsed configuration, as shown in fig. 31.

Referring now to fig. 31, while a rear actuation assembly 96 is depicted, it should be understood that the following description may also apply to the corresponding components of the front actuation assembly 94. When implant 10 is in the collapsed configuration, interior contact surfaces 46 of lower plate body 24 and upper plate body 26 may abut one another. Additionally, when collapsed, each actuation assembly 94, 96 may be disposed substantially entirely within an associated compartment 60, 62 (fig. 2) defined by the overlying channels 56, 58 of the plates 12, 18. The proximal end 120 of the nut receptacle 116 may be generally aligned with the proximal end 12 of the implant 10 along the transverse direction T. The drive shaft 98 may extend through the passages 56, 58 along the longitudinal direction L. One or both of the distal end 114 of the head 110 and the distal end 102 of the drive shaft 98 can abut or be adjacent the proximal face 90 of the second transverse projection 84 of the upper plate body 26. Proximal end 112 of head 110 may abut or be adjacent to distal face 92 of first lateral projection 82 of upper plate body 26. In this manner, head 110 may be aligned with transverse wall 76 of lower plate body 24 along transverse direction T.

An outer face 138 of first wedge 51 may abut or be adjacent to distal end 122 of nut receptacle 116 relative to proximal wedge assembly 124 in the collapsed configuration. The bottom base surface 142 of the first wedge-shaped member 51 may abut the base surface 68 of the rear channel 58 of the lower plate body 24, and the guide protrusion 144 of the first wedge-shaped member 51 may be received in the guide groove 70 of the rear channel 58 of the lower plate body 24. Proximal threaded portion 104 of drive shaft 98 may extend through U-shaped channel 158 of first wedge 51.

Second wedge-shaped member 52 may be positioned such that second ramp 188 abuts first ramp 148 at a location adjacent inner end 130 of first wedge-shaped member 51. An upper base surface 180 of the second wedge-shaped member 52 may abut the base surface 68 of the rear channel 58 of the upper plate body 26, and a guide protrusion 184 of the second wedge-shaped member 52 may be received within the guide slot 70 of the rear channel 58 of the upper plate body 26. Proximal threaded portion 104 of drive shaft 98 may extend through a U-shaped channel 202 of second wedge 52.

Third wedge 53 may be positioned such that its fourth ramp 234 abuts third ramp 190 of second wedge 52 at a location adjacent its inner end 170. Guide projection 236 of third wedge 53 may be received in guide groove 192 of second wedge 52. The drive shaft 98 may extend through the central bore 230 of the third wedge 53 with its threads 232 engaged with the proximal threaded portion 104 of the drive shaft 98.

Fourth wedge 54 may be positioned such that its outer face 258 abuts or is adjacent to inner face 226 of third wedge 53. An inner face 256 of the fourth wedge 54 may be positioned at or near the intermediate portion 108 of the drive shaft 98 (i.e., at or near the inner end of the proximal threaded portion 104). The bottom surface 262 of the fourth wedge-shaped member 54 may abut the base surface 68 of the rear channel 58 of the lower plate body 24, and the guide protrusions 270 of the fourth wedge-shaped member 54 may be received in the guide grooves 70 of the rear channel 58 of the lower plate body 24. The drive shaft 98 may extend through the central bore 264 of the fourth wedge 53 with its threads 266 engaging the proximal threaded portion 104 of the drive shaft 98.

It should be appreciated that, as set forth above, the distal wedge assembly 126 may effectively be a substantial mirror image of the proximal wedge assembly 124 about a vertical transverse plane positioned at the intermediate portion 108 of the drive shaft 98. Thus, the relative positions of wedges 51', 52, 53, 54 of distal wedge assembly 126 and distal threaded portion 106 of drive shaft 98 may be substantially similar to the relative positions of proximal wedge assembly 124 and proximal threaded portion 104 of the drive shaft. With respect to variations of the first wedge-shaped member 51', a first outer face 138' thereof may abut or be adjacent the proximal end 112 of the head 110 (fig. 5), while a second outer face 139 'of the first wedge-shaped member 51' may abut or be adjacent the proximal face 90 of the first transverse projection 82 of the upper plate body 26 (fig. 4).

The expansion of the implant 10 between the collapsed configuration and the first partially expanded configuration as shown in fig. 32-34 will now be discussed in accordance with an exemplary expansion mode. It should be understood that although fig. 32-34 depict simultaneous actuation of anterior and posterior actuation assemblies 94, 96 to extend implant 10 in unison, each of anterior and posterior actuation assemblies 94, 96 can be independently operated to provide non-uniform extension or contraction of implant 10 (i.e., lordosis).

During the first extension phase, the drive shaft 98 may be about its central shaft axis X₁Rotated in a first rotational direction (such as clockwise) such that the proximal threaded portion 104 is in its outer longitudinal direction L_E(i.e., proximal direction) provides a first or proximal driving force F₁And the distal threaded portion 106 is in its outer longitudinal direction L_E(i.e., in the distal direction) provides a second or distal driving force F₂. Threads 232, 178 of central bores 146, 176 of third wedge 53 and fourth wedge 54, respectively, may engage associated threaded portions 104, 106 of drive shaft 98 in the following manner: will respond to driving force F₁、F₂To the third wedge-shaped element 53 and the fourth wedge-shaped element 54, so that the third wedge-shaped element 53 and the fourth wedge-shaped element 54 are arranged in the outer longitudinal direction L_EAnd (4) translating.

Referring to fig. 34, as third wedge 53 and fourth wedge 54 translate, each of the following may occur: the bottom surface 262 of the fourth wedge 54 travels along the base surface 68 of the respective front channel 56, 58 of the lower plate 20; the guide projection 270 of the fourth wedge 54 travels within the guide slot 70 of the respective channel 56, 58; fourth ramp 234 of third wedge 53 rides along third ramp 190 of second wedge 52; and a guide projection of the third wedge 53The lug 236 rides in the channel 192 of the second wedge 52. As the fourth ramp 234 travels along the third ramp 190, the vertical distance D between the inferior bone contacting surface 28 and the superior bone contacting surface 30 may increase by a factor in the range of about 0.2 and about 1.0. When the fourth ramp 234 travels along the third ramp 190, the first driving force F₁May be transferred to at least second wedge member 52 such that second ramp 188 (not visible in fig. 34) travels along first ramp 148 of first wedge member 51, further increasing the distance D between bone contacting surfaces 28, 30 in vertical direction V by a factor in the range of about 0.2 to 1.0 (relative to the collapse distance D).

Sixth ramp 268 of fourth wedge 54 may approach first ramp 148 of first wedge 51 as fourth ramp 234 travels along third ramp 190 and as second ramp 188 travels along first ramp 148. In this example, a first expansion phase may be completed when sixth ramp 268 abuts first ramp 148, at which point protrusion 270 of fourth wedge member 54 may enter opening 152 of guide slot 150 of first wedge member 51 (FIG. 28). As set forth above, the geometry of guide protrusion 270 of fourth wedge-shaped member 54 may allow protrusion 270 to be simultaneously positioned within plate channel 70 and channel 150 of first wedge-shaped member 51 at the end of the first expansion phase (and at the beginning of the second expansion phase).

At the end of the first phase and the beginning of the second expansion phase, outer end 172 of second wedge-shaped member 52 and the entire second ramp 188 may be positioned intermediate inner end 130 and outer end 132 of first wedge-shaped member 51 with respect to longitudinal direction L. Further, the entire fourth ramp 234 may be positioned intermediate the downward apex 182 and the inner end 170 of the second wedge-shaped member 52, while the protrusion 236 of the third wedge-shaped member 53 may be positioned intermediate the stop feature 200 of the second wedge-shaped member 52 and the opening 198 of the guide slot 192, each relative to the longitudinal direction L. It should be understood that while the view of inner end 90 of first wedge-shaped member 51, and downward apex 182 and stop feature 200 of second wedge-shaped member 52 are each blocked in FIG. 34, such features are visible in FIG. 31.

Extension of implant 10 between the first partially extended configuration, as shown in fig. 32-34, and the fully extended configuration, as shown in fig. 35-37, will now be discussed in accordance with an exemplary extension mode.

Referring now to fig. 35-37, the implant 10 is shown to expand in unison at the end of the second expansion stage, which may be commensurate with a fully expanded configuration. As discussed above, it should be appreciated that anterior actuation assembly 94 and posterior actuation assembly 96 are each independently operable to provide non-uniform expansion or contraction of implant 10 (i.e., lordosis) between the first partially expanded configuration and the fully expanded configuration.

Referring to fig. 35-37, during the second extension phase, the drive shaft 98 may be further rotated in the first rotational direction about its central axis X₁And (4) rotating. The threads 232, 178 of the third wedge-shaped member 53 and the fourth wedge-shaped member 54, respectively, may be such that the third wedge-shaped member 53 and the fourth wedge-shaped member 54 may be further in the outer longitudinal direction L_EThe manner of translation continues to engage the associated threaded portions 104, 106 of the drive shaft 98. The second extension phase may be characterized as when the sixth ramp 268 travels along the first ramp 148, which further increases the distance D between the inferior bone contacting surface 28 and the superior bone contacting surface 30.

As the fourth wedge-shaped member 54 translates at the beginning of the second expansion phase, the protrusions 270 may transition from the channels 70 of the channels 56, 58 of the lower plate body 24 to the channels 150 of the first wedge-shaped member 51. In particular, the geometry of the first, second, third, and fourth portions 271, 272, 273, 274 of the protrusion 270 may engage the channels 150 of the first wedge member 51 such that the protrusion 270 exits the plate channel 70 and is fully received within the channels 150 of the first wedge member 51. Additionally, fifth ramp 240 of third wedge 53 may extend within guide channel 150 of first wedge 51 without contacting first wedge body 128.

During at least a portion of the second extension phase, sixth ramp 268 may ride along first ramp 148 while fourth ramp 234 rides along third ramp 190, resulting in relative movement between second wedge 52 and each of third wedge 53 and fourth wedge 54 in longitudinal direction L and vertical direction V. Relative movement between second wedge-shaped member 52 and third and fourth wedge-shaped members 53, 54 during the second stage may cause second ramp 188 to separate from first ramp 148 relative to vertical V, or so asOtherwise becoming distant from the first ramp. In addition, such relative movement between second wedge-shaped member 52 and third and fourth wedge-shaped members 53, 54 may be induced by a reaction force applied to at least one of second wedge-shaped member 52, third wedge-shaped member 53, and fourth wedge-shaped member 54. For example, when a component of the implant 10 (such as a stop feature in the channels 56, 58, the channel 70, or other portion of the plate bodies 24, 26) obstructs the second wedge-shaped member 52 in the outer longitudinal direction L_ECan generate a reaction force. In another non-limiting example, the second ramp 124 and the sixth ramp 180 may travel at or near the same rate along the first ramp 148 until, in the proximal wedge assembly 124, the outer face 178 of the second wedge 52 abuts the distal end 122 of the nut receptacle 116, and, in the distal wedge assembly 126, the outer face 178 of the second wedge 52 abuts the proximal face 90 of the first transverse projection 82. In each of proximal wedge assembly 124 and distal wedge assembly 126, the aforementioned abutment may impede second wedge 52 along outer longitudinal direction L_EWhile fourth ramp 234 continues to travel along third ramp 190 and sixth ramp 268 continues to travel along first ramp 148, thereby driving second wedge 52 upward relative to first wedge 51.

In another non-limiting example, a reaction force may occur at the beginning of the second extension phase, causing the fourth ramp 234 to travel along the third ramp 190 once the sixth ramp 268 travels along the first ramp 148. In such an example, in each of the proximal and distal wedge assemblies 124, 126, the fourth ramp 234 may travel along the third ramp 190 until the guide projection 236 of the third wedge 53 abuts the stop feature 200 of the guide slot 192 of the second wedge 52, after which the sixth ramp 268 may continue to travel along the first ramp 148 without any relative movement between the second wedge 52 and the third and fourth wedges 53, 54 in the longitudinal direction L and the vertical direction V. Thus, in each of the two preceding non-limiting examples, the second expansion phase may include at least one portion or sub-phase (which involves relative movement between the second wedge-shaped piece 52 and each of the third and fourth wedge-shaped pieces 53, 54 with respect to the longitudinal direction L and the vertical direction V), and at least another portion or sub-phase (during which the second, third and fourth wedge-shaped pieces 52, 53, 54 are driven together along the longitudinal direction L and the vertical direction V without any relative movement therebetween).

In yet another non-limiting example, relative movement may occur between the second wedge-shaped member 52 and each of the third and fourth wedge-shaped members 53, 54 along the longitudinal direction L and the vertical direction V during substantially the entire second stretch stage. In this example, in each of the proximal and distal wedge assemblies 124, 126, a reaction force may occur at the beginning of the second expansion phase, causing the fourth ramp 234 to travel along the third ramp 190 once the sixth ramp 268 travels along the first ramp 148 and the guide projection 236 of the third wedge 53 to simultaneously travel within the guide slot 192. Further, in this example, the guide protrusion 236 of the third wedge 53 may abut the stop feature 200 of the second wedge 52 substantially while the outer face 178 of the second wedge 52 abuts the distal end 122 of the nut receptacle 116.

At the end of the second expansion phase, the outer end 172 of the second wedge 52 may be substantially aligned with the outer end 132 of the first wedge 51 in the vertical direction V in the proximal wedge assembly 124, and the outer end 172 of the second wedge 52 may be substantially aligned with the second outer face 139 'of the first wedge 51' in the distal wedge assembly. Additionally, in each wedge assembly 124, 126, third wedge 53 and fourth wedge 54 may each be completely intermediate inner end 130 and outer end 132 of first wedge 51 and inner end 170 and outer end 172 of second wedge 52. Similarly, at the end of the second expansion phase, downward vertex 182 of second wedge-shaped member 52 may be spaced upward from upward vertex 140 of first wedge-shaped member 51.

Throughout the extension of implant 10, respective first wedges 51, 51' of proximal and distal wedge assemblies 124, 126 may remain adjacent the outer ends of proximal and distal threaded portions 104, 106 of drive shaft 98. Additionally, the second wedge 52, the third wedge 52 of each wedge assembly 124, 12653 and the fourth wedge-shaped element 54 can be extended in the outer longitudinal direction L_EAnd (4) moving. Thus, the point of contact between wedge assemblies 124, 126 and upper and lower plates 12, 28 is initially located near proximal and distal ends 12, 14 of implant 10 (as in the case of first wedges 51, 51' coupled to lower plate 20), or moves toward proximal and distal ends 12, 14 of implant 10 during extension (as in the case of second wedge 52 coupled to upper plate 22). Such an arrangement provides enhanced support and stability to the implant 10 during extension, particularly with respect to reactive forces, such as internal forces, applied to the implant 10 in the vertical direction V within the intervertebral space 5. However, it should be understood that in other embodiments (not shown), the respective first wedges 51, 51' of proximal and distal wedge assemblies 124, 126 may be located near the inner ends of threaded portions 104, 106 of drive shaft 98, and that second, third, and fourth wedges 52, 53, 54 of each wedge assembly 124, 126 may be in the inner longitudinal direction L during extension_IAnd (4) moving.

The operation of the implant 10 to achieve lordosis will now be discussed.

Referring now to fig. 38-40, anterior actuation assembly 94 and posterior actuation assembly 96 can be independently driven in a manner that provides implant 10 with a lordotic profile, as set forth above. In other words, front and rear actuating assemblies 94, 96 may operate in a manner such that at least one of lower and upper plates 20, 22 is inclined relative to the other plate 20, 22 relative to transverse direction T. In some embodiments, at least one of the plates 20, 22 may be centered about first and second central axes X relative to the other plate 20, 22₁Is inclined. This may be accomplished by placing the wedge assemblies 124, 126 of one of the front and rear actuating assemblies 94, 96 at a different degree of extension than the wedge assemblies 124, 126 of the other actuating assembly 94, 96. In the exemplary forwardly convex configuration of fig. 38-40, in the rearward actuation assembly 96, its proximal and distal wedge assemblies 124, 126 may be generally in the collapsed configuration (fig. 39), while in the forward actuation assembly 94, its wedge assemblies 124, 126 may extend to approximate the firstPartially extended configuration, thereby causing upper plate 22 to tilt relative to lower plate 20 with a lordotic angle β (fig. 40) relative to transverse direction T.

The first distance D between the inferior and superior bone contacting surfaces 28, 30 when at least one of the plates 20, 22 is convexly inclined relative to each other₁(measured along the vertical direction L and aligned with the central axis X of the front actuating assembly 94)₁Intersect) may be shorter or longer than the second distance D between the lower bone contacting surface 28 and the upper bone contacting surface 30₂(measured along the vertical direction L and aligned with the central axis X of the rear actuating assembly 96)₁An intersection). In addition, when at least one of the plates 20', 22' is convexly inclined relative to the other, the vertical distance D between the lower plate 20 'and the upper plate 22' at the anterior side 16 'of the implant 10' is₃Is shorter or longer than the vertical distance D between the plates 20', 22' at the posterior side 18' of the implant 10₄. As shown in FIG. 40, D₃And D₄One of which may be as small as zero, in which case the internal contact surfaces 46 at the respective sides 16, 18 of the implant 10 may define a fulcrum point. In some embodiments, inner faces 44 of lower and upper plate bodies 24, 26 may be curved, sloped, or may otherwise define a gap therebetween at one or both of anterior side 16 and posterior side 18 such that at least one of plates 20, 22 may be frontwardly sloped (i.e., lordosis may be induced from the collapsed configuration) when one of anterior and posterior actuation assemblies 94, 96 is in the collapsed configuration.

It should be understood that the lordotic profile shown in fig. 38-40 represents only one of many lordotic profiles achievable with the implant 10 of the present disclosure. For example, a practitioner may actuate front actuation assembly 94 to a first extended configuration and rear actuation assembly 96 to a second extended configuration to provide first distance D₁At a second distance D₂The difference between them. In particular, a physician may actuate one of anterior actuation assembly 94 and posterior actuation assembly 96 to a fully extended configuration while the other actuation assembly 96, 94 remains near the fully collapsed configuration to provide implant 10 with a maximum lordotic angle β in the range of about 0 degrees and about 45 degrees. It should be understood that the physician may use the actuating assembly 94. 96 are independently disposed in the collapsed configuration, the fully extended configuration, or any position therebetween to provide the implant 10 with the desired lordotic angle beta. It should also be understood that an initial lordotic angle β may be built into the implant 10. In such embodiments, the lower and upper bone plates 20, 22 may be configured such that their bone contacting surfaces 28, 30 are oriented in the lordotic angle β when the implant 10 is in the collapsed configuration.

At least because lower plate 20 is rotationally interlocked with first wedge-shaped element 51, upper plate 22 is rotationally interlocked with second wedge-shaped element 52, second wedge-shaped element 52 is rotationally interlocked with third wedge-shaped element 53, third wedge-shaped element 53 being able to rotate about respective central axis X₁Tilting is made possible by rotation relative to fourth wedge-shaped element 54 (as shown in fig. 41) and fourth wedge-shaped element 54 is rotationally interlocked with lower plate 20 (direct rotational interlock, as in the first extension phase, or rotational interlock via rotational interlock with first wedge-shaped element 51, which is rotationally interlocked with lower plate 20). It should be appreciated that the fourth wedge 54 acts as a hinge for the implant 10, which facilitates lordotic tilting of at least one of the plates 20, 22. By using the drive shaft 98 as a "through pin" for the hinge, the strength of the hinge can be increased and the number of parts required to complete the hinge can be reduced. In addition, base surfaces 68 of channels 56, 58, base surfaces 142, 180, 262 of each wedge assembly 124, 126, and ramp surfaces 148, 188, 190, 234, 268 of each wedge assembly 124, 126 cooperatively provide increased stability and strength to implant 10 to withstand internal body forces during and after implantation.

It should also be appreciated that the implant 10 provides the physician with enhanced freedom in achieving the desired extension of the implant 10 and/or ordering of lordosis. In particular, after a desired amount of extension and/or lordosis of the implant 10 in the intervertebral space 5 is predetermined, the physician may insert the implant 10 in the collapsed configuration into the intervertebral space 5 in a medial-lateral direction, as shown in fig. 1. If both extension and lordosis are desired, the physician may extend the implant 10 to a partially extended configuration in unison and then extend or retract the implant 10 in an inconsistent manner to achieve the desired lordosis angle β of the implant 10. The implant 10 can expand or contract in various ways, including, for example: independently operating one of the actuating assemblies 94, 96; operating both actuation assemblies 94, 96 simultaneously but at different rates; operating both actuating assemblies 94, 96 simultaneously but in different rotational directions; or any combination of the foregoing. As disclosed herein, the design of the implant 10 allows the physician to utilize any of the aforementioned patterns of expansion, contraction, and/or lordosis to achieve the final desired configuration, and to adjust the configuration of the implant 10 as needed, including during subsequent physical surgery on the patient. The compact nature of the implant 10 in the collapsed configuration allows the implant 10 to fit within a standard lumbar disc space. In addition, because the implant 10 can be adjusted to achieve an extension of maximum 30mm or more and lordosis of maximum 45 degrees or more, the physician can use the implant 10 in many different locations within the spine and for many different purposes.

Referring now to fig. 42, a second embodiment of the implant 10' is shown. It will be appreciated that the second embodiment may be similar to the first embodiment of the implant shown in figures 1 to 41. Accordingly, the same reference numerals used above with respect to the first embodiment may also be used with an "apostrophe" designation with respect to the second embodiment. It should also be understood that the components (and features thereof) of the implant 10' of the second embodiment may be similar to those of the first embodiment, unless otherwise noted below.

The lower plate 20 'and the upper plate 22' of the second embodiment may define a single vertical hole 34 'extending through the implant 10' along the vertical direction V. The anterior portion 36' and the posterior portion 38' of the implant 10 may be located on opposite sides of the vertical bore 34 '. The distal portion 40' of the implant 10' may be spaced apart from the vertical bore 34' in a distal direction.

Referring now to fig. 43, the front and rear channels 56', 58' of each of the lower and upper plate bodies 24', 26' may include a proximal channel portion 55 'that is contoured to match the outer profile of the nut receptacle 116'. At the distal end of each proximal channel portion 55', each plate body 24', 26 'may define a shoulder 57'. The shoulder 57 'of the lower plate body 24' may be configured to abut the outer faces 138 'of the first wedges 51' of the front and rear actuating assemblies 94', 96'. Shoulder 57 'of upper plate body 22' may be configured to abut or at least be adjacent to outer face 178 'of second wedge member 52' of actuating assembly 94', 96' when actuating assembly 94', 96' is in the fully extended configuration.

Each of the channels 56', 58' of the lower plate body 24' may define a first pair of cutouts 59' and a second pair of cutouts 61' spaced apart from each other along the longitudinal direction L. In each channel 56', 58', a first pair of cutouts 59 'may be opposite each other along the transverse direction T, and a second pair of cutouts 61' may be opposite each other along the transverse direction T. Although the view of FIG. 43 only shows the front notches 61' of each pair, it should be understood that the rear notches 61' of each pair may be a mirror image of the associated front notches 61 '. The first and second pairs of cutouts 59', 61' may each communicate with the plate guide channel 70 'of the lower plate body 24', and may be sized to allow the base protrusions 142 'of the first wedge member 51' to be inserted into the plate guide channel 70 'during assembly of the implant 10'.

Each of the channels 56', 58' of the upper plate body 26 'may define a pair of cutouts 63' that are generally centered with respect to the longitudinal direction L. In each channel 56', 58', the central cuts 63' of each pair may be opposite each other along the transverse direction T. Although the view of FIG. 43 only shows the rear central cutouts 63' of each pair, it should be understood that the front central cutouts 63' of each pair may be a mirror image of the associated rear central cutouts 63 '. The central cutouts 63' may each communicate with the plate guide slots 70' of the upper plate body 26' and may be sized to allow the bottom protrusions 270' (fig. 44-46) of the fourth wedge 54' of each actuating assembly 94', 96' to be inserted into the plate guide slots 70' during assembly of the implant 10 '.

With continued reference to fig. 43, each of the plate guide channels 70' can define a proximal end 70a ' and a distal end 70b '. In lower plate body 24', proximal end 70a' of plate guide channel 70 'may optionally be configured to abut a base projection of first wedge 51 "of proximal wedge assembly 124', and distal end 70b 'of plate guide channel 70' may optionally be configured to abut a base projection of first wedge 51 '" of distal wedge assembly 126'. Although the base protrusions of the first wedge-shaped pieces 51 ", 51'" of this embodiment are not visible in fig. 43, they are not visible in the drawingsIt should be understood that these base projections may be configured similarly to the base projections 144, 144' shown in fig. 10-15. In upper plate body 26', proximal ends 70a' of plate guide channels 70 'may optionally be configured to abut base protrusions 184' of second wedges 52 'of proximal wedge assemblies 124' during operation of the implant, such as when each respective actuation assembly 94', 96' is in a fully extended configuration. Similarly, distal end 70b 'of plate guide channel 70' may optionally be configured to abut base projection 184 'of second wedge 52' of distal wedge assembly 126 'during operation of implant 10', such as when each respective actuation assembly 94', 96' is in a fully extended configuration. It should be appreciated that proximal and distal ends 70a ', 70b' of channel 70 'of upper plate 22 can inhibit second wedge member 52' from following outer longitudinal direction L during extension of implant 10_EThe movement of (2).

At the distal portion 40 'of the lower plate body 24', the inner face 44 'may define a single transverse slot 73' elongated along the transverse direction T. The distal portion 40' of the upper plate body 26' may define a single lateral protrusion 83' that protrudes beyond the interior contact surface 46' of the upper plate body 26 '. When implant 10' is in the collapsed configuration, lateral projections 83' of upper plate body 26' may nest within lateral slots 73' of lower plate body 24 '. The transverse projection 83' may define a pair of opposed recesses 85' extending into the projection 83' along the transverse direction T. Recess 85 'may be configured to receive therein portions of head 110' of drive shaft 98 'of front and rear actuation assemblies 94' and 96', at least when implant 10' is in the collapsed configuration.

It should be understood that the third and fourth wedges 53', 54' of each of the actuation assemblies 94', 96' of the second embodiment may differ from their counterparts in the first embodiment. Referring to fig. 44-46, the third wedge body 216 'may define an upper surface 231' that extends between the inner face 226 'and the fourth ramp 234' along the longitudinal direction L. The third wedge body 216 'may define a vertical bore 233' extending through the fourth ramp 234 'and the guide projection 236', and may further define a pair of arms 235', 237' extending from the inner face 226 'to the outer face 228'. The vertical bore 233' may communicate with the central bore 230' of the third wedge 53 '. Screw of central hole 230A portion of the striations 232' may be defined on the inner side of the arms 235', 237 '. Each of the pair of arms 235', 237' may define a lower surface 239 '(fig. 46) facing towards the axis X of the central aperture 230' of the third wedge 53₂And (4) inclining. Rounded portions 244' of the third wedges 53' may extend downwardly from the lower surfaces 239' of the arms 235', 237' and may have a generally semi-circular profile in a vertical transverse plane. The rounded portion 244' of the present embodiment may optionally be non-oblique with respect to the longitudinal direction L. The rounded portion 244' may surround at least a portion of the central bore 230' of the third wedge body 216 '.

Fourth wedge-shaped body 246' may define an outer longitudinal direction L from outer face 258_EAn extended front basket 253'. Front basket 253 'may provide an increased length to bottom base surface 262' of fourth wedge-shaped body 246 'and thus increased stability as bottom base surface 262' abuts and/or translates along channel base surface 68. An outer face 258 'of fourth wedge-shaped body 246' may be a first outer face thereof, and front basket 253 'may define a second outer face 255' along outer longitudinal direction L_ESpaced from the first outer face 256'. A second outer face 255' may be positioned at the outer end 250' of the fourth wedge-shaped body 246 '. A bottom surface 262' of the fourth wedge-shaped body 246' may extend along the longitudinal direction L from the inner face 256' to a sixth ramp 268' and may extend along a portion of the basket 253 '. Sixth ramp 268 'may extend from bottom surface 262' to second outer face 255 'of fourth wedge-shaped body 246'. The guide protrusions 270' of the fourth wedge-shaped body 246' of the second embodiment may be configured similarly to the guide protrusions 270' of the first embodiment.

The basket 253 'may define a central recessed portion 257' extending along the longitudinal direction L. Central recess 257 'may be characterized as an extension along central bore 264' of fourth wedge-shaped body 246 'of basket 253'. The central recessed portion 257' may divide an upper portion of the basket 253' into a pair of arms 259', 261', each extending generally along the longitudinal direction L and each having an upper surface 263' facing toward the central bore axis X of the fourth wedge 54₃And (4) inclining. The basket 253 'may also define a slot 265' configured to receive the rounded portion 244 'of the third wedge body 216'. The slot 265' may have a pairCorresponds to the rounded profile of the rounded portion 244 'of the third wedge body 216', and may allow the rounded portion 244 'of the third wedge body 216' to surround the central bore axis X of the third wedge body 216₃Rotating within the slot 265. Central recess 257 'may also define a portion of threads 266' of central bore 264 'of fourth wedge-shaped body 246'. The fourth wedge body 216 'may define a vertical bore 267' extending through the basket 253 'at its outer end 250'. Vertical bores 233', 267' of third wedge-shaped member 216 'and fourth wedge-shaped member 246' may be aligned with each other along vertical direction V.

As shown in fig. 44 and 45, third wedge body 216 'may be coupled to fourth wedge body 54' such that: rounded portion 244 'of third wedge body 216' is received within slot 265 'of fourth wedge body 246'; the inner face 226' of the third wedge body 216' abuts or is adjacent to the first outer face 256' of the fourth wedge body; and outer face 228 'of third wedge-shaped body 216' is substantially aligned with second outer face 255 'of fourth wedge-shaped body 246' along vertical direction V. When plates 20', 22' are in the neutral (i.e., non-lordotic) configuration, a gap 275' is defined between the lower surfaces 239' of arms 235', 237' of third wedge body 216' and the upper surfaces 263' of arms 259', 261' of fourth wedge body 246 '. Gap 275' and angled arm surfaces 239', 263' may be configured to allow third wedge body 216' to rotate relative to fourth wedge body 246', as shown in FIG. 45. Additionally, the rounded portion 244' of the third wedge body 216' and the slot 265' of the fourth wedge body 246' may be cooperatively configured to translationally attach the third wedge 53' and the fourth wedge 54' together relative to translation along the drive shaft 98 '.

Referring now to fig. 47, a second embodiment of implant 10 'is shown with each wedge assembly 124', 126 'in a fully extended configuration (with upper plate 22' removed for visualization purposes). It should be appreciated that the actuating assemblies 94', 96' and wedge assemblies 124', 126' of the second embodiment may operate as set forth above with respect to the first embodiment.

Referring now to fig. 48 and 49, actuation assemblies 94', 96' of implant 10 'can be independently operated such that upper plate 22' is opposed relative to lower plate 20Is inclined in the transverse direction T to provide the implant 10' with a lordotic profile, as explained above. As shown in fig. 48, the lower bone contacting surface 28 'and the upper bone contacting surface 30' can be oriented with a lordotic angle β in the range of about 0 degrees and about 25 degrees. As set forth above, when at least one of the plates 20', 22' is convexly inclined relative to the other, the central axis X between the lower bone contacting surface 28 'and the upper bone contacting surface 30' associated therewith₁First vertical distance of intersection D₁May be shorter or longer than the associated central axis X between the bone contacting surfaces 28', 30₁Second vertical distance of intersection D₂. In addition, when at least one of the plates 20', 22' is convexly inclined relative to the other, the vertical distance D between the lower plate 20 'and the upper plate 22' at the anterior side 16 'of the implant 10' is₃Is shorter or longer than the vertical distance D between the plates 20', 22' at the posterior side 18' of the implant 10₄As set forth above.

As shown in the exemplary forward-convex configuration of fig. 49, in forward actuation assembly 94', its proximal and distal wedge assemblies 124', 126' may be approximated in the collapsed configuration, while in rearward actuation assembly 96', its wedge assemblies 124', 126' may be extended near or at the fully extended configuration, causing the forward-convex of upper plate 22' to tilt. It should be understood that while fig. 49 shows lower and upper plates 20', 22' vertically separated to provide an unobstructed view of actuation assemblies 94', 96', plates 20', 22' are shown with the same lordotic angle β as shown in fig. 48.

It should be understood that although the illustrated embodiment depicts the implant 10 having a pair of actuation assemblies 94, 96, in other embodiments (not shown), the implant 10 may have a single actuation assembly 94 to extend the implant 10 in the vertical direction V. In one such embodiment, plates 20, 22 can be configured to remain in contact with one another in a hinge-like manner at one of anterior side 16 and posterior side 18 such that operation of a single actuation assembly 94 extends implant 10 vertically and, at the same time, provides lordosis.

Referring now to fig. 50, drive tool 300 may be configured to engage anterior actuation assembly 94 and posterior actuation assembly 96 of implant 10. For example, the drive tool 300 may include a handle 302 coupled to a first driver 304 and a second driver 306 spaced apart from each other along the transverse direction T. The first driver 304 may carry a first drill bit 308 configured to engage the drive coupling of the front actuation assembly 94, and the second driver 306 may carry a second drill bit 310 configured to engage the drive coupling of the rear actuation assembly 96. For example, in the illustrated embodiment, the first drill bit 308 and the second drill bit 310 may each define a hexagonal profile configured to engage a corresponding hexagonal profile of the socket bore 118 of a corresponding actuation assembly 94, 96.

The drive tool 300 may include one or more selector switches that allow the physician to select between various operating modes of the tool 300. For example, the first selector switch 312 may be switched between a first drive mode a, a second drive mode B, and a third drive mode C. In the first driving mode a, the tool 300 may be set to operate only the first driver 304. In the second driving mode B, the tool 300 may be set to operate the first driver 304 and the second driver 306 simultaneously. In the third mode C, the tool 300 may be set to operate only the second driver 306.

The second selector switch 314 may be in communication with the first driver 304. For example, the second selector switch 314 may be switched between a first position E in which the tool 300 is arranged to rotate the first driver 304 in a clockwise direction and a second position F; in this second position F, the tool 300 is arranged to rotate the first driver 304 in a counter-clockwise direction. Similarly, the third selector switch 316 may be in communication with the second driver 306. For example, the third selector switch 316 may be switched between a first position G in which the tool 300 is arranged to rotate the second driver 306 in a clockwise direction and a second position H; in this second position H, the tool 300 is arranged to rotate the second driver 306 in a counter-clockwise direction.

The fourth selector switch 318 may allow the physician to select a torque and/or speed setting of the first driver 304. The fifth selector switch 320 may allow the physician to select the torque and/or speed settings of the second driver 306. Accordingly, first selector switch 312, second selector switch 314, third selector switch 316, fourth selector switch 318, and fifth selector switch 320 allow the practitioner to use tool 300 to operate front actuation assembly 94 and rear actuation assembly 96 in unison or independently as desired. Additionally, the selector switch may also allow the physician to independently adjust the rotational direction, speed, and/or torque of each of the actuation assemblies 94, 96.

Although the present disclosure has been described in detail, it should be understood that various changes, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims. Additionally, any of the embodiments disclosed herein can incorporate features disclosed with respect to any of the other embodiments disclosed herein. Furthermore, the scope of the present disclosure is not intended to be limited to the specific embodiments described in the specification. One of ordinary skill in the art will readily appreciate from the disclosure that processes, machines, manufacture, compositions of matter, means, methods, or steps, presently existing or later to be developed that perform substantially the same function or achieve substantially the same result as the corresponding embodiments described herein may be utilized according to the present disclosure.