阅读说明：本技术 用于治疗癌症的氮杂芳环酰胺衍生物 (Azaaromatic cyclic amide derivatives for the treatment of cancer ) 是由 朱程刚 杨铉 张朝春 塔利·约翰·J 陈超乐 包丽茗 徐良亮 于 2020-03-30 设计创作，主要内容包括：涉及用于治疗癌症的氮杂芳环酰胺衍生物。具体而言,涉及氮杂芳环酰胺衍生物的制备方法和用途。涉及式(I)、式(II)、式(III)、式(IV)、式(V)所示的氮杂芳环酰胺衍生物和苯胺基-嘧啶化合物及其药学上可接受的盐,所述化合物或其盐可通过调节某些突变形式的表皮生长因子受体而用于治疗或预防疾病或病症。还涉及包含所述化合物或其盐的药物组合物,以及使用所述化合物及其盐治疗由EGFR或HER2或HER4所介导的多种疾病的方法。(To nitrogen heteroaromatic amide derivatives useful in the treatment of cancer. In particular to a preparation method and application of nitrogen heterocyclic aromatic ring amide derivatives. To aza-aromatic cyclic amide derivatives of formula (I), formula (II), formula (III), formula (IV), formula (V) and anilino-pyrimidine compounds and their pharmaceutically acceptable salts, which compounds or salts can be used for the treatment or prevention of diseases or disorders by modulating certain mutated forms of epidermal growth factor receptors. Also relates to pharmaceutical compositions comprising the compounds or salts thereof, and methods of using the compounds and salts thereof to treat various diseases mediated by EGFR or HER2 or HER 4.)