阅读说明：本技术 一种防血栓血管内支架 (Thrombosis-proof intravascular stent ) 是由 李亮 张金龙 王茂强 崔豹 于 2020-12-31 设计创作，主要内容包括：本专利涉及一种防血栓血管内支架,包括支架本体,所述支架本体采用镍钛合金材料经激光切割热定型、电解剖光制成,所述支架本体上设置有X线下显影的标记点；所述支架本体包括一体设置的覆膜支架和裸支架,所述覆膜支架的内表面设置聚四氟乙烯覆膜；所述覆膜支架由多个支撑段固定连接组成,所述支撑段的厚度差异化设置,相邻两个所述支撑段的厚度不同；所述覆膜支架和裸支架的内表面均设置疏水涂层。本发明结构简单,操作方便,通过在支架本体的内表面设置疏水涂层,有效防止血栓,提高了支架的通畅性；且覆膜支架为分段式结构,各支撑段的厚度差异化设置,柔性好,能够适应各种曲度的病变血管,且设置有X线下显影的标记点,便于支架的识别定位。(The patent relates to an anti-thrombus intravascular stent, which comprises a stent body, wherein the stent body is made of a nickel-titanium alloy material through laser cutting, heat setting and electrolytic polishing, and mark points for developing under X-rays are arranged on the stent body; the stent body comprises a covered stent and a bare stent which are integrally arranged, and a polytetrafluoroethylene covering film is arranged on the inner surface of the covered stent; the covered stent is formed by fixedly connecting a plurality of supporting sections, the thickness of the supporting sections is arranged in a differentiated manner, and the thickness of two adjacent supporting sections is different; and the inner surfaces of the covered stent and the bare stent are both provided with hydrophobic coatings. The invention has simple structure and convenient operation, and effectively prevents thrombus and improves the smoothness of the stent by arranging the hydrophobic coating on the inner surface of the stent body; and the covered stent is of a sectional type structure, the thickness of each supporting section is differentiated, the flexibility is good, the covered stent can adapt to diseased blood vessels with various curvatures, and mark points for developing under X-rays are arranged, so that the covered stent is convenient to identify and position.)

1. The thrombus-preventing intravascular stent is characterized by comprising a stent body (1), wherein the stent body (1) is made of a nickel-titanium alloy material through laser cutting, heat setting and electrolytic polishing, and mark points for developing under X-rays are arranged on the stent body (1);

the stent body (1) comprises a covered stent (11) and a bare stent (12) which are integrally arranged, and a polytetrafluoroethylene covering film is arranged on the inner surface of the covered stent (11); the covered stent (11) is composed of a plurality of supporting sections which are fixedly connected, the thickness of the supporting sections is differentiated, and the thickness of the two adjacent supporting sections is different.

And the inner surfaces of the covered stent (11) and the bare stent (12) are both provided with hydrophobic coatings.

2. The anti-thrombotic endovascular stent according to claim 1, wherein the support section comprises a plurality of support cells comprising consecutively arranged peaks and valleys;

in two adjacent supporting units, the wave crest of one supporting unit is connected with the wave trough of the other supporting unit.

3. An anti-thrombotic endovascular stent according to claim 2, wherein the stent graft (11) comprises at least three support segments, and the number of support segments is an odd number.

4. An anti-thrombotic endovascular stent according to claim 3, wherein the thickness of the strut section is equal to the thickness of the strut elements that make up the strut section;

the covered stent (11) comprises supporting sections with two thicknesses, the supporting sections comprise supporting sections with a first thickness and supporting sections with a second thickness, the thickness of the supporting sections at two ends of the covered stent (11) is the first thickness, and the first thickness is larger than the second thickness.

5. An anti-thrombotic endovascular stent according to claim 4, wherein the first thickness is 2-3 times greater than the second thickness.

6. An anti-thrombotic endovascular stent according to claim 1, wherein the stent body (1) has a diameter of 2mm-35mm and the stent body (1) has a length of 20mm-130 mm.

7. An anti-thrombotic endovascular stent according to claim 1, wherein marker points are provided at both ends of the stent body (1).

8. The thromboresistant intravascular stent of claim 1 or 7, wherein the marker points are provided at the boundaries of the covered stent (11) and the bare stent (12).

9. The anti-thrombotic endovascular stent according to claim 8, wherein the marker points are rounded protrusion marker points (8), the rounded protrusion marker points (8) comprise rounded protrusions, and a visualization groove is arranged on the rounded protrusions, and is filled with visualization material.

10. An anti-thrombotic endovascular stent according to claim 9, wherein the rounded raised marker points (8) are provided at the peaks of the support cells of at least one support section in the middle of the stent body (1);

the number of the marking points is one or more.

Technical Field

This patent belongs to intravascular stent technical field, particularly relates to a prevent thrombus endovascular stent.

Background

The stent implantation is a common operation formula for treating vascular diseases such as vascular occlusion, vascular rupture/rupture, aneurysm/pseudo-aneurysm, arterial dissection and the like, and is also a key step for treating portal hypertension Through Intrahepatic Portosystemic Shunt (TIPS) of internal jugular vein, an intravascular stent is an essential material, and the patency of the stent has a decisive influence on treatment prognosis. The current clinical routine stents are: the other stents except the heparin coating covered stent need to be orally taken with anticoagulation and/or antiplatelet drugs for a long time to prevent thrombosis in the stent from causing stent blockage, but the stent blockage still occurs in a high proportion.

Therefore, it is urgently needed to provide an antithrombotic intravascular stent which has an antithrombotic function and can avoid stent blockage caused by thrombus formed in the stent without oral administration of anticoagulant and/or antiplatelet drugs.

Disclosure of Invention

In view of the above analysis, the present invention aims to provide an anti-thrombus intravascular stent, which is used to solve the problem that the existing stent itself does not have an anti-thrombus function, and even if an anticoagulant and/or antiplatelet drug is orally taken for a long time, the stent cannot be prevented from being blocked due to thrombus formation in the stent.

The purpose of the invention is realized as follows:

an anti-thrombus intravascular stent comprises a stent body, wherein the stent body is made of a nickel-titanium alloy material through laser cutting, heat setting and electrolytic polishing, and mark points for X-ray lower development are arranged on the stent body; the stent body comprises a covered stent and a bare stent which are integrally arranged, the covered stent is provided with a polytetrafluoroethylene covering film, the covered stent is formed by fixedly connecting a plurality of supporting sections, the thickness of the supporting sections is arranged in a differentiated manner, and the thickness of two adjacent supporting sections is different; the inner surfaces of the covered stent 11 and the bare stent 12 are both provided with hydrophobic coatings.

In a preferred embodiment of the present invention, the supporting section comprises a plurality of supporting units, and the supporting units comprise wave crests and wave troughs which are arranged in series; in two adjacent supporting units, the wave crest of one supporting unit is connected with the wave trough of the other supporting unit.

In a preferred embodiment of the present invention, the stent graft comprises at least three support sections, and the number of the support sections is odd.

In a preferred embodiment of the present invention, the thickness of the support section is equal to the thickness of the support unit constituting the support section; the covered stent comprises supporting sections with two thicknesses, the supporting sections comprise supporting sections with first thicknesses and supporting sections with second thicknesses, the first thicknesses are larger than the second thicknesses, the thicknesses of the two adjacent supporting sections are different, and the thicknesses of the supporting sections at the two ends of the covered stent are the first thicknesses.

In a preferred embodiment of the invention, the first thickness is 2-3 times the second thickness.

In a preferred embodiment of the invention, the diameter of the stent body is 2mm-35mm, and the length of the stent body is 20mm-130 mm.

In a preferred embodiment of the present invention, the two ends of the stent body are provided with mark points.

In a preferred embodiment of the present invention, the mark point is located at a boundary between the covered stent and the bare stent.

In a preferred embodiment of the present invention, the mark points are round and smooth bump mark points, each round and smooth bump mark point includes a round and smooth bump, the round and smooth bump is provided with a developing tank, and a developing material is filled in the developing tank.

In a preferred embodiment of the present invention, the rounded convex mark points are disposed at the wave crests of the supporting units of at least one supporting section in the middle of the stent body; the number of the marking points is one or more.

In a preferred embodiment of the present invention, the marking points are marking portions, a plurality of the marking portions are uniformly distributed on the circumference of the outermost support unit, and the marking portions are arranged parallel to the axis of the support; at least a part of the marking portion is made of an alloy containing a developing material.

In a preferred embodiment of the present invention, the marking portion is detachably provided with a developing member made of an alloy containing a developing material.

In a preferred embodiment of the present invention, the developing member is connected to the marking portion by a snap-fit connection.

In a preferred embodiment of the present invention, the developing member is a collar, and a collar mounting portion is provided at a marking end of the marking portion; the lantern ring installation part is a U-shaped elastic sheet, the U-shaped elastic sheet and the marking part are integrally formed, a blocking part is arranged on a side lug of the U-shaped elastic sheet, and the blocking part is used for blocking the lantern ring.

In a preferred embodiment of the present invention, the blocking portions are protruding structures, the number of the blocking portions on each side ear is two, the blocking portions are disposed at the front and rear ends of the side ear, and the distance between the two blocking portions on the same side ear is equal to the length of the collar.

In a preferred embodiment of the present invention, the developing member is connected to the marking portion by a screw connection.

In a preferred embodiment of the present invention, the developing member is a threaded sleeve, the threaded sleeve is a circular threaded sleeve, and the main body of the marking portion is a round rod provided with an external thread.

In a preferred embodiment of the present invention, the developing member is connected to the marking portion by a combination of a screw connection and a snap connection; the developing piece is a threaded sleeve, the main body of the marking part is a round rod, external threads are arranged on the round rod, the front end of the round rod is a threaded section, and the rear end of the round rod is connected with the support; the front end of the round rod is provided with a U-shaped elastic sheet, each side lug of the U-shaped elastic sheet is provided with a blocking part at the outer side of the opening end, and the distance from the blocking end surface of each blocking part to the concave point of the U-shaped elastic sheet is smaller than the length of the screw sleeve.

In a preferred embodiment of the present invention, the distance from the blocking end surface of the blocking portion to the concave point of the U-shaped elastic piece is equal to the length of 1/2 thread sleeves, and the length of the thread section at the front end of the round rod is at least the length of 1/2 thread sleeves.

In a preferred embodiment of the invention, the U-shaped elastic piece side lug is provided with a first blocking part, the round bar is also provided with a second blocking part, and the distance between the first blocking part and the second blocking part is equal to the length of the screw sleeve.

Compared with the prior art, the invention can realize at least one of the following beneficial effects:

a) according to the thrombus-preventing intravascular stent provided by the invention, the hydrophobic material coating is arranged on the surface of the inner wall of the stent, so that the stent has a thrombus-preventing function, specifically, the stent body comprises the covered stent and the bare stent, the hydrophobic coatings are arranged on the inner side surfaces of the covered stent and the bare stent, blood is separated from the inner surface of the stent body by the hydrophobic coatings, the blood is prevented from directly contacting with the stent body, the purpose of thrombus formation is achieved, and thrombus formation in the stent can be avoided without orally taking anticoagulant and/or antiplatelet drugs.

b) According to the thrombus-preventing intravascular stent provided by the invention, the stent body is of a sectional structure, the thicknesses of the supporting sections are arranged in a differentiated manner, the thicknesses of the two adjacent supporting sections are different, and different supporting sections have different supporting strengths and softness, so that the thrombus-preventing intravascular stent can adapt to diseased blood vessels with various curvatures; the two ends of the stent, the boundary of the covered stent and the bare stent are all provided with marking points which can be developed under X-rays and are used for developing the position of the stent in a blood vessel in an operation, so that the stent can be conveniently identified and positioned.

c) According to the thrombus-preventing intravascular stent provided by the invention, the mark points are arranged at the subsection positions of the support sections, so that the stent can be accurately released to a blood vessel lesion position, the operation efficiency and the accuracy are improved, and the subsection-arranged stent has high flexibility due to the thickness difference of each section, so that the requirements of different lesion positions of a blood vessel on different support forces can be met, and the thrombus-preventing intravascular stent can adapt to lesion blood vessels with various curvatures.

d) The thrombus-preventing intravascular stent provided by the invention has the advantages of simple structure and simple and convenient transportation; the stent body is made of nickel-titanium alloy materials through laser cutting heat setting and electro-polishing, and has the advantages of abrasion resistance, corrosion resistance and superelasticity.

Drawings

In order to more clearly illustrate the embodiments of the present specification or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments described in the embodiments of the present specification, and other drawings can be obtained by those skilled in the art according to the drawings.

FIG. 1 is a schematic structural diagram of an anti-thrombotic endovascular stent in an embodiment of the invention;

FIG. 2 is a schematic structural diagram of a segmented antithrombotic endovascular stent in an embodiment of the invention;

FIG. 3 is a schematic structural view of a segmented antithrombotic endovascular stent-graft in an embodiment of the invention;

FIG. 4 is a first schematic structural diagram of an anti-thrombotic endovascular stent with marker points according to an embodiment of the present invention;

FIG. 5 is a schematic structural diagram of a thrombus-prevention endovascular stent with marker points according to an embodiment of the present invention;

FIG. 6 is a schematic structural diagram of a marking portion according to an embodiment of the present invention;

FIG. 7 is a schematic structural diagram of a U-shaped resilient piece of the marking portion according to the embodiment of the present invention;

FIG. 8 is a schematic structural view of a developing member of a rectangular sleeve structure of a marking portion according to an embodiment of the present invention;

FIG. 9 is a schematic structural diagram of another marking portion according to an embodiment of the present invention;

fig. 10 is a schematic structural diagram of a circular ring nut in an embodiment of the present invention.

Reference numerals:

1-a stent body; 11-a covered stent; 12-a bare stent; 2, coating a film on the inner liner; 3-a biological glue layer; 4-a first support section; 5-a second support section; 6-a third support section; 7-outermost support unit; 8-smooth bump mark points; 9-a marker portion; 91-a developing member; 92-U-shaped shrapnel; 93-thread segment.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are some embodiments of the present application, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

For the purpose of facilitating understanding of the embodiments of the present application, the following description will be made in terms of specific embodiments with reference to the accompanying drawings, which are not intended to limit the embodiments of the present application.

A specific embodiment of the present invention, as shown in fig. 1 to 2 and 4 to 5, discloses an anti-thrombus intravascular stent, wherein the inner side surface (the side contacting blood) of the stent is coated with a hydrophobic material, so as to achieve the purpose of anti-thrombus formation, specifically, the anti-thrombus intravascular stent comprises a stent body 1, the stent body 1 is a cylindrical structure, a partial stent cover of the stent body 1 comprises a stent cover 11 and a bare stent 12 which are integrally arranged, a liner membrane 2 is arranged on the inner surface of the stent cover 11, the liner membrane 2 is preferably made of a polytetrafluoroethylene material, and the bare stent 12 is not provided with the liner membrane 2; the inner surface of the stent body 1 is coated with hydrophobic materials, that is, the inner surface of the lining film 2 of the covered stent 11 and the inner surface of the bare stent 12 are both provided with hydrophobic coatings, the hydrophobic coatings separate blood from the inner surface of the stent body 1 and prevent the blood from directly contacting the stent body 1, so that the condition that the stent body 1 promotes the coagulation reaction in the blood is effectively avoided, and the thrombus is prevented.

In this embodiment, the hydrophobic coating is a nano coating of a super-hydrophobic coating, the nano coating is a fluorine-containing nano polymer, the fluorine-containing nano polymer is a fluorocarbon nano polymer, a fluorosilane nano polymer or a fluoromolybdenum nano polymer, and the thickness of the nano coating is 50-5000 nm. The fluorine-containing nano polymer has good super-hydrophobicity, the nano coating covers the surface of the stent body 1, which is in contact with blood, to form a protective film, the protective film separates the blood from the inner surface of the stent body 1, and the stent body 1 is prevented from promoting the blood coagulation reaction in the blood, so that the thrombus is effectively prevented. The setting of nanometer coating extension support body 1's life alleviates patient's misery, reduces the time of being in hospital, saves treatment cost.

In the embodiment, the stent body 1 is made of a nickel-titanium alloy material, is made by laser cutting heat setting and electro-polishing, and has the advantages of wear resistance, corrosion resistance and superelasticity.

When the thrombus-preventing intravascular stent is used, the stent is fixed in the access sleeve at the front end of the delivery catheter, the access sleeve restrains the naked stent part of the stent, and the stent is guided into the delivery catheter from the hemostatic valve of the guide sheath without removing the access sleeve before use; the passage sleeve is provided with a mark which can be used as a mark for determining the correct depth of the passage sleeve inserted into the large-scale valve component, the conveying catheter is compatible with the small-diameter guide wire, and the working length is 75 cm; stent covered stent 11 the mounting sleeve is provided with a removable sleeve for deployment wire through the catheter shaft for stent deployment. The tail end of the delivery catheter is provided with a seat assembly which comprises a central hemostatic guide wire port, an irrigation port and a deployment thread/deployment knob port. When the compressed stent is conveyed to the appointed position in the blood vessel by the conveying catheter, the stent unfolding knob is operated to release and unfold the stent, and the unfolded covered stent supports the inner wall of the blood vessel.

In this embodiment, the stent body 1 is a segmented structure, as shown in fig. 2 and 4, the stent body 1 is formed by fixedly connecting a plurality of corrugated supporting sections, the stent graft 11 of the stent body 1 includes at least three supporting sections, the number of the supporting sections is odd, each supporting section is formed by a plurality of supporting units, and the supporting units are corrugated structures and include continuously arranged wave crests and wave troughs. In two adjacent supporting units, the wave crest of one supporting unit is connected with the wave trough of the other supporting unit. The thickness differentiation of each section of supporting of tectorial membrane support 11 sets up, and the thickness that two sections adjacent supported the section is different, and different sections of supporting have different support intensity and compliance, can adapt to the blood vessel of various curvatures.

In a preferred embodiment of the present invention, as shown in fig. 3, the thickness of each supporting section of the stent graft 11 is equal to the thickness of the supporting unit constituting the supporting section, and the thickness of each supporting section of the stent graft 11 is 0.02mm-0.2mm, preferably 0.02mm-0.1mm, which can reduce the amount of the vessel lumen diameter occupied by the stent. Each of the supporting sections of the stent graft 11 includes a first thickness and a second thickness, the first thickness is larger than the second thickness, the thicknesses of the two adjacent supporting sections are different, the thicknesses of the supporting sections at the two ends of the stent graft 11 are the first thicknesses, the stent graft 11 adopts a thin and thick interval arrangement mode, the flexibility can be improved, and the supporting strength can be kept.

Exemplarily, the stent graft 11 of the stent body 1 includes three support sections, as shown in fig. 3, specifically includes a first support section 4, a second support section 5 and a third support section 6, wherein the second support section 5 is located in the middle, the thickness of the second support section 5 is smaller than the thickness of the first support section 4 and the third support section 6, due to the thickness difference, the thickness of the support section at the middle portion of the stent is small, and the support section is easy to bend at the middle portion, and has good anterograde performance, and is suitable for tortuous blood vessels, and meanwhile, the thickness of the two ends of the stent is large, so that the stent graft has strong support strength, and it is ensured that enough strength is provided to support the blood vessel lumen.

In a preferred embodiment of this embodiment, the first thickness is L₁And the second thickness is L₂，L₁Is L₂2-3 times of the total weight of the product. Illustratively, the first thickness L₁Between 0.06mm and 0.18mm, a second thickness L₂The length of the first thickness supporting section and the length of the second thickness supporting section are set according to the shape, the curvature of the blood vessel and the length of the blood vessel at the position of a lesion between 0.03mm and 0.06mm, and the flexibility of the stent can be improved through the differential setting of the thickness of the stent wall, so that the support of the blood vessels with various curvature shapes is met.

More preferably, the thickness is L₁The supporting section is also provided with an auxiliary bending section, wherein the auxiliary bending section is that the supporting section with large thickness is provided with a thickness L₃The auxiliary bending section consists of 1-3 continuous supporting units, and the length of the auxiliary bending section is L in thickness₁1/10, the thickness of the auxiliary bent section is greater than the second thickness L₂Is a first thickness L₁2/3-4/5.

In a preferred embodiment of this embodiment, the stent body 1 has a diameter of 2mm to 35mm, the total length of the stent body 1 is 20mm to 130mm, and the length of the support section having the first thickness is 1 to 3 times the length of the support section having the second thickness.

In a preferred embodiment of the present embodiment, the bare stent 12 has a length of 20mm, the stent graft 11 has a length of 80mm, the supporting segment of the first thickness has a length of 30mm, and the supporting segment of the second thickness has a length of 20 mm.

In this embodiment, the stent body 1 is provided with a marking point which can be developed under X-ray for developing the position of the stent in the blood vessel during the operation, so as to facilitate the identification and positioning of the stent.

In a preferred embodiment of this embodiment, as shown in fig. 5, end mark points are provided at both ends of the stent, the end mark points are mark parts 9 provided at both ends of the stent body 1, the mark parts 9 are fixed on the outermost support unit 7, or the mark parts 9 are integrally formed with the outermost support unit 7, the plurality of mark parts 9 are uniformly distributed on the circumference of the outermost support unit 7, and the mark parts 9 are provided parallel to the axis of the stent.

In a preferred embodiment of the present embodiment, at least a part of the marking portion 9 is made of an alloy containing a developing material, and the marking portion 9 is welded to the holder outermost support unit 7.

In a preferred embodiment of this embodiment, the marking portion 9 is detachably provided with a developing member 91, and the developing member 91 is made of an alloy containing a developing material including one or more of gold, platinum-tungsten, palladium, platinum-iridium, rhodium, and tantalum.

In a preferred embodiment of this embodiment, the developing member 91 is mounted on the marking portion 9 by a snap-fit connection or a screw-fit connection.

In one embodiment of the snap-fit connection, the developing member 91 is a collar, and a collar mounting portion is provided at a marking end of the marking portion 9. As shown in fig. 6 to 8, the collar mounting portion is a U-shaped elastic piece 92, the U-shaped elastic piece 92 and the marking portion 9 are integrally formed, and a blocking portion is arranged on a side ear of the U-shaped elastic piece 92 and used for blocking the collar.

Particularly, the stop part is protruding structure, and the quantity of the stop part on every side ear is two, sets up both ends around the side ear, and the distance between two stop parts on same side ear equals the length of the lantern ring, through the both sides ear of extrusion U-shaped shell fragment 92, makes the size of the open end of U-shaped shell fragment 92 be less than the ring mouth size of the lantern ring, adorns the lantern ring on U-shaped shell fragment 92, and U-shaped shell fragment 92 resets and props the inner wall of the lantern ring, and the stop part restriction is fixed the lantern ring. The technical scheme that the developing piece 91 with the annular structure is sleeved on the U-shaped elastic piece 92 is adopted, so that the operation is simple, and the manufacturing cost is low.

In a technical scheme of the threaded connection, the developing part 91 is a threaded sleeve, the threaded sleeve is a circular threaded sleeve, an internal thread is arranged, the main body of the marking part 9 is a round rod, an external thread is arranged on the round rod, and the threaded sleeve is screwed on the round rod provided with the external thread. Because the support mounting is in the blood vessel in-process and accomplish the installation back, the swivel nut of support tip only receives the effect of force along the blood vessel central line, can not receive the effort that makes the swivel nut rotatory, adopts threaded connection's mode, can guarantee the installation stability of swivel nut, effectively prevents that the swivel nut from droing.

In order to further improve the installation stability of the developing member 91 and prevent the developing member 91 from falling off, in a preferred embodiment of the present embodiment, the developing member 91 is connected to the marking portion 9 by means of a snap connection or a combination of a threaded connection, as shown in fig. 9 to 10, specifically, the developing member 91 is a threaded sleeve, the marking portion 9 is a round bar, the round bar is provided with an external thread, the front end of the round bar is a threaded section 93, the rear end of the round bar is connected to the bracket, the front end of the round bar is provided with a U-shaped elastic sheet 92, each side ear of the U-shaped elastic sheet 92 is provided with a blocking portion outside the opening end, and the distance from the blocking end surface of the blocking portion to the concave point of the U-shaped elastic sheet 92 is smaller than the length of.

Furthermore, the distance from the blocking end surface of the blocking part to the concave point of the U-shaped elastic sheet 92 is equal to the length of 1/2 thread sleeves, and the length of the thread section 93 at the front end of the round rod is at least 1/2 thread sleeves. The length of the thread at the front end of the round rod is at least 1/2 threads, so that the installation stability of the threads can be guaranteed, the threads are effectively prevented from falling off, and the processing difficulty is reduced.

Still further, a first blocking portion is arranged on a side ear of the U-shaped elastic sheet 92, a second blocking portion is further arranged on the round rod, and the distance between the first blocking portion and the second blocking portion is equal to the length of the screw sleeve. Through the effect that the screw thread is limited and the two blocking parts block bidirectionally, the double protection effect is achieved on preventing the screw sleeve from falling off, and the working stability of the support is greatly improved.

In a preferred embodiment of the present invention, at least one end of the stent and the middle of the stent are provided with a marker, which can visualize the reached position of the stent in the blood vessel during the operation, and facilitate the identification and positioning of the stent. Specifically, a marker is disposed on at least one support section located in the middle of the stent. The number of the marking points is one or more, smooth convex marking points 8 are arranged at the wave crests of the supporting unit at least one end of the supporting section, each smooth convex marking point 8 comprises a smooth bulge, a developing tank is arranged on each smooth bulge, and developing materials are filled in the developing tank to form the marking points with the developing function. The smooth convex mark points 8 can also be arranged at the middle position of the bracket, namely the smooth convex mark points 8 are arranged at the wave crest of a supporting unit in the middle of the bracket, the smooth convex mark points 8 are arranged at the two ends and the middle position of the bracket, and the mounting position of the bracket is more visually displayed in the operation process.

In a preferred embodiment of this embodiment, as shown in fig. 4 to 5, a marker point is set at a boundary between the covered stent 11 and the bare stent 12 of the stent, the marker point is a smooth convex marker point 8, the smooth convex marker point 8 is uniformly set on an annular boundary between the covered stent 11 and the bare stent 12, or a developing marker ring is sleeved at the boundary between the covered stent 11 and the bare stent 12, and the developing marker ring is made of a developing material.

In this embodiment, the mark points at the two ends of the stent may be the mark portion 9 of this embodiment, or may be the same mark as the development mark at the middle of the stent, that is, the smooth protruding mark points 8 are arranged at the wave crests of the outermost support units 7 of the two end support sections.

The smooth protrusions arranged at the wave crests of the supporting unit can be of a solid structure or a structure with a hole in the center. The number and the interval of the round bulges are determined according to the actual treatment requirement.

In a preferred embodiment of this embodiment, the segmented stent is provided with marking points at the segments, and because the thickness of different supporting segments of the segmented stent is different, the supporting strength and flexibility of different supporting segments are different, and the length and thickness of different supporting segments can be designed according to the blood vessel at the lesion.

Specifically, the support with the sectional type structure comprises a plurality of support sections, each support section is composed of a plurality of support units, the support units are of a corrugated structure, the thickness of each support section of the support body 1 is set in a differentiated mode, the thickness of two adjacent support sections is different, different support sections have different support strength and softness, mark points are arranged at the connection positions of the two support sections, and the mark points of the smooth protruding structures are arranged at the wave crests where the two support sections are connected. The marking points are arranged at the segmented positions of the supporting sections, so that the stent can be accurately released to the position of the vascular lesion, the operation efficiency and the accuracy are improved, the stent arranged in the segmented mode has high flexibility due to the thickness difference of each section, the requirements of different lesion positions of the blood vessel on different supporting forces can be met, and the stent can adapt to the lesion blood vessels with various curvatures.

Compared with the prior art, the thrombus-prevention intravascular stent provided by the embodiment at least has the following beneficial effects:

(1) the support body is the sectional type structure, and the thickness differentiation of each section of supporting sets up, and the thickness that two sections adjacent supported the section is different, and different sections of supporting have different support intensity and compliance, can adapt to the pathological change blood vessel of various curvatures.

(2) The two ends of the stent, the boundary of the covered stent and the bare stent are all provided with marking points which can be developed under X-rays, so that the position of the stent in a blood vessel can be developed in an operation, and the stent can be conveniently identified and positioned.

(3) The marking points are arranged at the segmented positions of the supporting sections, so that the stent can be accurately released to the position of the vascular lesion, the operation efficiency and the accuracy are improved, the stent arranged in the segmented mode has high flexibility due to the thickness difference of each section, the requirements of different lesion positions of the blood vessel on different supporting forces can be met, and the stent can adapt to the lesion blood vessels with various curvatures.

(4) The stent has the advantages of simple structure and simple and convenient transportation, the stent body is made by laser cutting and heat setting, and the stent body is made of nickel-titanium alloy material, so that the stent has the advantages of wear resistance, corrosion resistance and superelasticity.

Example 2

In another embodiment of the present invention, an anti-thrombus intravascular stent is disclosed, which is different from embodiment 1 in that: the outer surface of the stent body 1 is provided with a biological glue layer 3, and the biological glue layer 3 is used for adhering the stent body 1 to the vessel wall. As shown in fig. 4-5, the outer surface of the covered stent 11 is provided with a biological glue layer 3; or, the outer surface of the bare stent 12 is provided with the biological glue layer 3; or the biological glue layer 3 wraps the whole outer surface of the stent body 1.

Through the biological glue layer 3 that can adhere the vascular wall at the surface parcel one deck of support body 1, can closely adhere together with the vascular wall after the support release, avoid the support aversion, avoid the blood flow to flow backward.

In a preferred embodiment of this embodiment, the thickness of the biological glue layer 3 is 0.01mm-0.02mm, and the coagulation time is 3-5 minutes, so as to avoid the defects that the operation difficulty is increased due to too fast coagulation, and the operation time is prolonged and the failure rate is increased due to too slow coagulation.

Compared with the prior art, the thrombus-preventing intravascular stent provided by the embodiment can adhere to the biological adhesive layer of the vascular wall through the surface coating layer on the stent body, can be closely adhered to the vascular wall after the stent is released, avoids the displacement of the stent, avoids the reverse flow of blood flow, and improves the success rate of treating vascular injury diseases by implanting the stent.

The above-mentioned embodiments, objects, technical solutions and advantages of the present application are described in further detail, it should be understood that the above-mentioned embodiments are merely exemplary embodiments of the present application, and are not intended to limit the scope of the present application, and any modifications, equivalent substitutions, improvements and the like made within the spirit and principle of the present application should be included in the scope of the present application.