Microbicidal pyridine carboxamide derivatives
阅读说明：本技术 杀微生物的吡啶甲酰胺衍生物 (Microbicidal pyridine carboxamide derivatives ) 是由 S·伦迪安 M·R·莫纳克 C·拉姆比尔斯 R·比奥德格尼斯 M·布勒姆 于 2018-12-11 设计创作，主要内容包括：披露了具有式(I)的化合物,其中取代基是如在权利要求1中所定义的,所述化合物可用作杀有害生物剂并且尤其是杀真菌剂。<Image he="241" wi="700" file="DDA0002547004880000011.GIF" imgContent="drawing" imgFormat="GIF" orientation="portrait" inline="no"></Image>(Compounds of formula (I) wherein the substituents are as defined in claim 1 are disclosed which are useful as pesticides and especially fungicides.)
1.A compound having the formula (I):
wherein the content of the first and second substances,
R1is C1-C12Alkyl or C1-C6A haloalkyl group;
R2is hydroxy, C2-C6Acyloxy, C2-C6Halogenoacyloxy, C1-C6Alkoxy radical C1-C6Alkoxy radical, C1-C6Halogenoalkoxy radical C1-C6Alkoxy radical, C1-C6Alkoxy radical C1-C6Haloalkoxy, C2-C6Acyloxy C1-C6Alkoxy radical, C2-C6Halogenoacyloxy C1-C6Alkoxy, or C2-C6Acyloxy C1-C6A haloalkoxy group;
R3is hydrogen, C1-C6Alkyl radical, C1-C6Alkoxy or C3-C8A cycloalkyl group;
R4and R5Each independently is C1-C12Alkyl radical, C3-C8Cycloalkyl radical, C1-C6Haloalkyl or C1-C6Alkoxy radical C1-C6An alkyl group;
R6is hydrogen, C1-C12Alkyl radical, C3-C8Cycloalkyl, aryl or heteroaryl, wherein the heteroaryl moiety is a 5-or 6-membered aromatic ring comprising 1,2,3 or 4 heteroatoms independently selected from N, O and S, and wherein the aryl and heteroaryl moieties are each optionally substituted with 1,2 or 3 heteroatoms, which may be the same or different, selected from R9Substituted with the substituent(s);
R7is hydrogen, C1-C12Alkyl radical, C3-C8Cycloalkyl, aryl or heteroaryl, wherein the heteroaryl moiety is a 5-or 6-membered aromatic ring comprising 1,2,3 or 4 heteroatoms independently selected from N, O and S, and wherein the aryl and heteroaryl moieties are each optionally substituted with 1,2 or 3 heteroatoms, which may be the same or different, selected from R9Substituted with the substituent(s); or
R6And R7Together with the carbon atom to which they are attached form C3-C8A cycloalkyl ring, said ring optionally substituted by 1,2 or 3 substituents which may be the same or different and are selected from R9Substituted with the substituent(s);
R8is C1-C12Alkyl radical, C3-C8Cycloalkyl, aryl, aryloxy, heteroaryl, or heteroaryloxy, wherein the heteroaryl moiety is a 5-or 6-membered aromatic ring containing 1,2,3, or 4 heteroatoms independently selected from N, O and S, and wherein the aryl and heteroaryl moieties are each optionally substituted with 1,2, or 3 heteroatoms, which may be the same or different, selected from R9Substituted with the substituent(s);
R9is halogen, cyano, C1-C4Alkyl radical, C1-C4Haloalkyl, C1-C4Alkoxy, or C1-C4A haloalkoxy group;
or a salt or N-oxide thereof.
2. The compound of claim 1, wherein R1Is methyl or ethyl.
3. A compound according to claim 1 or claim 2, wherein R2Is hydroxy, acetoxy or 2-methyl-propionyloxymethoxy.
4. A compound according to any one of claims 1 to 3, wherein R3Is hydrogen.
5. A compound according to any one of claims 1 to 4, wherein R4And R5Each independently is C1-C4An alkyl group.
6. A compound according to any one of claims 1 to 5, wherein R6Is hydrogen or C1-C4An alkyl group.
7. A compound according to any one of claims 1 to 6, wherein R7Is hydrogen, C1-C6Alkyl radical, C3-C6Cycloalkyl, aryl or heteroaryl, wherein the heteroaryl moiety is a 5-or 6-membered aromatic ring comprising 1 or 2 heteroatoms independently selected from N and O, and wherein the aryl and heteroaryl moieties are each optionally substituted with 1 or 2 heteroatoms which may be the same or different selected from R9Is substituted with the substituent(s).
8. A compound according to any one of claims 1 to 5, wherein R6Is hydrogen and R7Is C3-C6A cycloalkyl group.
9. A compound according to any one of claims 1 to 8, wherein R8Is C1-C6Alkyl radical, C3-C6Cycloalkyl, aryl or heteroaryl, wherein the heteroaryl moiety is a 5-or 6-membered aromatic ring comprising 1 or 2 heteroatoms independently selected from N and O, and wherein the aryl and heteroaryl moieties are each optionally substituted with 1 or 2 heteroatoms which may be the same or different selected from R9Is substituted with the substituent(s).
10. The compound of any one of claims 1 to 9, wherein R8Is phenyl or naphthyl, wherein the phenyl and naphthyl moieties are each optionally substituted by 1 or 2 groups which may be the same or different selected from R9Is substituted with the substituent(s).
11. The compound of any one of claims 1 to 10, wherein R9Is halogen, C1-C3Alkyl, or C1-C3A haloalkyl group.
12. An agrochemical composition comprising a fungicidally effective amount of a compound of formula (I) according to any one of claims 1 to 11.
13. The composition according to claim 12, further comprising at least one additional active ingredient and/or an agrochemically acceptable diluent or carrier.
14. A method for controlling or preventing infestation of useful plants by phytopathogenic microorganisms, wherein a fungicidally effective amount of a compound of formula (I) according to any one of claims 1 to 11, or a composition comprising this compound as active ingredient, is applied to the plants, parts thereof or the locus thereof.
15. Use of a compound of formula (I) according to any one of claims 1 to 11 as a fungicide.
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