阅读说明：本技术 一种超声易显影轻量型补片及其制备方法 (Ultrasonic easily-developed light-weight patch and preparation method thereof ) 是由 吴俊� 杨继婷 耿如霞 孙亮 张榆锋 李海燕 李星奥 余韩梅 于 2019-12-06 设计创作，主要内容包括：本发明涉及医疗器械领域,具体的说,是一种超声易显影轻量型补片及其制备方法。本发明包括补片,所述补片上安装有带气囊的显影毛细管；同时本发明还包括一种超声易显影轻量型补片的制备方法,在补片上安装带有气囊的显影毛细管；所述显影毛细管采用医用级聚合物材料制成,通过分段热熔的方式在所述显影毛细管上形成粘结部,相邻两粘结部之间形成所述气囊；以解决现有轻量型补片在植入深度较大时成像检测困难的问题。(The invention relates to the field of medical instruments, in particular to an ultrasonic easily-developed light-weight patch and a preparation method thereof. The invention comprises a patch, wherein a developing capillary tube with an air bag is arranged on the patch; meanwhile, the invention also comprises a preparation method of the ultrasound developing-easy light-weight patch, wherein a developing capillary tube with an air bag is arranged on the patch; the developing capillary is made of medical-grade polymer materials, bonding parts are formed on the developing capillary in a segmented hot melting mode, and the air bag is formed between every two adjacent bonding parts; the problem of imaging detection difficulty when the implantation depth is large in the existing light-weight patch is solved.)

1. An ultrasonic easily-developable light-weight patch is characterized in that: the patch comprises a patch (3), wherein a developing capillary (2) with an air bag (1) is arranged on the patch (3).

2. An ultrasonically developable lightweight patch according to claim 1, characterized by: the developing capillary (2) is a medical polypropylene capillary.

3. An ultrasonically developable lightweight patch according to claim 1, characterized by: the patch (3) is woven into a mesh structure by medical polypropylene monofilaments.

4. An ultrasonically developable lightweight patch according to claim 3, characterized by: the developing capillary (2) is combined with the patch (3) in a weaving mode.

5. An ultrasonically developable lightweight patch according to claim 1, characterized by: a plurality of bonding parts are sequentially arranged on the developing capillary tube (2), and the air bag (1) is arranged between two adjacent bonding parts.

6. An ultrasonically developable lightweight patch according to claim 5, characterized by: the bonding part is formed by bonding the upper wall and the lower wall of the inner cavity of the developing capillary (2).

7. An ultrasonically developable lightweight patch according to claim 1, characterized by: the developing capillary tubes (2) are sequentially and parallelly arranged on the patch (3).

8. A preparation method of an ultrasonic easily-developed light-weight patch is characterized by comprising the following steps: a developing capillary (2) with an air bag (1) is arranged on the patch (3);

the developing capillary tube (2) is made of medical-grade polymer materials, bonding parts are formed on the developing capillary tube (2) in a segmented hot melting mode, and the air bag (1) is formed between every two adjacent bonding parts.

9. The method of making an ultrasonically developable lightweight patch according to claim 8, wherein: the patch (3) is made into a mesh structure by weaving medical polypropylene monofilaments through a warp knitting machine;

weaving the developing capillary (2) into the patch (3) with a mesh structure to prepare a composite patch (3);

and (3) carrying out heat setting on the composite patch (3) to prepare the ultrasonic easily-developed light-weight patch (3).

10. The method of making an ultrasonically developable lightweight patch according to claim 9, characterized by: and the composite patch (3) is naturally cooled and shaped at normal temperature after being subjected to heat shaping.

Technical Field

The invention relates to the field of medical instruments, in particular to an ultrasonic easily-developed light-weight patch and a preparation method thereof.

Background

An incisional hernia is a breach of the abdominal wall with or without a bulge mass in the area of the original surgical incision. It is presently believed that as many as 13% of abdominal surgical incisions eventually develop into incisional hernias. Today, the vast majority of incisional hernias are treated by placing a patch over the abdominal wall defect.

Lightweight patches with reduced polypropylene content and larger pore sizes have been shown to significantly reduce the inflammatory response and promote better in vivo adjacent tissue ingrowth into the patch structure. At present, the light-weight patch is an ideal incisional hernia repair material and has wide application prospect.

According to practical experience of previous work of the inventor, the imaging resolution of deep tissues by ABUS (automated 3D Breast ultrasound) is relatively low. As the depth of imaging of the ABUS increases, the resolvability of its images gradually decreases. When the lightweight patch is implanted to a depth of less than 30mm (about 60% of total abdominal hernia patients), the patch can be effectively distinguished from adjacent tissues by using a coronal view. While abdominal hernia patients with thick residual fat layer have a patch that is not significantly different from adjacent tissues in coronal view due to the deep implantation position of the patch, resulting in a deep position patch that is difficult to identify by the mesh texture of a lightweight patch.

Disclosure of Invention

The invention aims to provide an ultrasonic easily-developable light-weight patch, which solves the problem that the conventional light-weight patch is difficult to image and detect when the implantation depth is large.

In order to solve the problems, the invention adopts the following technical means:

the light-weight patch comprises a patch, wherein a developing capillary tube with an air bag is mounted on the patch.

Preferably, the developing capillary is medical polypropylene capillary.

Further, the patch is woven into a mesh structure through medical polypropylene monofilaments.

Further, the developer capillary is woven in combination with the patch.

Furthermore, a plurality of bonding portions are sequentially arranged on the developing capillary, and the air bag is arranged between two adjacent bonding portions.

Further, the bonding part is formed by bonding the upper wall and the lower wall of the inner cavity of the developing capillary.

Further, the developing capillaries are sequentially mounted on the patch in parallel.

Compared with the common patch, the ultrasound easily-developed light-weight patch disclosed by the invention has the following beneficial effects:

the sound velocity and the acoustic impedance between the air bag structure and the soft tissue are changed greatly, so that the acoustic reflection quantity of the patch is increased remarkably, a high-echo image is formed on the interface of the air bag and the soft tissue, and the imaging significance of ultrasonic equipment on the patch is enhanced effectively. The invention can effectively solve the imaging detection difficulty of the light-weight patch and effectively solve the problem of low imaging resolution of the ABUS at a deeper position.

A preparation method of an ultrasonic easily-developed light-weight patch comprises the steps of mounting a developing capillary tube with an air bag on the patch;

the developing capillary is made of medical-grade polymer materials, bonding parts are formed on the developing capillary in a segmented hot melting mode, and the air bag is formed between every two adjacent bonding parts.

Preferably, the patch is made into a mesh structure by weaving medical grade polypropylene monofilaments through a warp knitting machine;

weaving the developing capillary into the patch with a mesh structure to prepare a composite patch;

and (3) carrying out heat setting on the composite patch to prepare the ultrasonic easily-developable light-weight patch.

Further, the composite patch is naturally cooled and shaped at normal temperature after being subjected to heat shaping.

The preparation method of the ultrasonic easily-developed light-weight patch disclosed by the invention has the following beneficial effects:

the patch is formed by spinning a medical polypropylene monofilament into a sheet, a plurality of air bags are formed on a medical polypropylene capillary tube in a segmented hot melting mode, namely, a plurality of node structures with inner walls attached to each other are formed on the polypropylene capillary tube in a segmented hot melting mode, an air bag is formed between every two adjacent node structures, and the developing capacity of the patch in an ultrasonic developing instrument is enhanced by using the polypropylene capillary tube with the air bag.

Drawings

FIG. 1 is a schematic diagram of the construction of an ultrasound developable lightweight patch of the present invention.

Fig. 2 is a graph of the imaging results of an ultrasound contrast light weight patch of the present invention under an ABUS scan.

Fig. 3 is a flow chart of a method of making an ultrasound developable lightweight patch of the present invention.

Wherein, 1-air bag, 2-developing capillary and 3-patch.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to the embodiments and the accompanying drawings. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

Please refer to fig. 1, which illustrates an ultrasound easily developable lightweight patch, including a patch 3, wherein the patch 3 is made of medical polypropylene monofilament, and is woven into a mesh structure through a 2-3 comb-band empty-through warp-knitted structure, and the diameter of the medical polypropylene monofilament is 0.1 mm;

a plurality of developing capillary tubes 2 used for improving the developing capability are arranged on the patch 3 through bonding or weaving and other processes, the developing capillary tubes 2 adopt medical-grade polypropylene capillary tubes, and a plurality of sequentially arranged fusion nodules are formed on the developing capillary tubes 2 in a multi-section fusion mode, so that a plurality of bonding parts are formed even if the inner walls of the developing capillary tubes 2 are fused and combined up and down, and a closed cavity structure is formed between two adjacent bonding parts, namely the air bag 1 for improving the developing capability;

the bonding portions can form a plurality of air bags 1 in the developing capillary 2, one purpose of the structure of the air bags 1 is to facilitate the cutting of the product at the later stage, so that the most air bags 1 are not damaged due to the cutting, and the other purpose is to enable the developing capillary 2 to form a plurality of separated bright spots (the bonding portions are used for separating the adjacent air bags 1), so that the identification degree of the image is improved.

In the embodiment, the developing capillary 2 provided with the structure of the air bag 1 is specially added according to an ultrasonic imaging mechanism, the sound velocity and the acoustic impedance between the structure of the air bag 1 and the soft tissue are changed greatly, so that the sound reflection quantity of the patch 3 is increased remarkably, a high echo image is formed on the interface between the air bag 1 and the soft tissue, the imaging significance of the developing capillary 2 by an ultrasonic device is effectively enhanced, and by utilizing the imaging localization of the developing capillary 2, even if the depth of the implanted patch 3 is too large and the body of the patch 3 cannot be imaged clearly, the patch 3 can be detected by the clear imaging of the developing capillary 2, so that the imaging detection difficulty of the light-weight patch 3 is effectively solved, and the problem of low imaging resolution of the ABUS at a deeper position is effectively solved.

Meanwhile, in the actual operation process, the developing capillary 2 is often set to be parallel to each other, that is, the developing capillary 2 is distributed on the patch 3 in order, so that the influence of the developing capillary 2 after ultrasonic imaging is more attractive, and the condition that the observation is influenced by disorder or mutual staggering is avoided.

In the light-weight patch easy to develop by ultrasound disclosed by the invention, the patch is implanted to 30mm below the surface of a pig belly cut piece, the imaging effect under ABUS is shown in figure 2, from the imaging photo shown in figure 2, the light spot generated by the structure of the air bag 1 arranged on the developing capillary tube 2 can be clearly observed, the identification degree of the light spot is obviously higher than that of the developing soft tissue around and the developing of the patch 3 per se, it can be obviously found from the figure that the developing identification degree of the patch 3 is obviously reduced, the developing of the soft tissue around is extremely similar, the structure of the air bag 1 on the developing capillary tube 2 is obviously different from the surrounding image, namely, even after the patch 3 is implanted more deeply, the developing capillary tube 2 can better and more clearly image than the patch 3, through the detection of the developing capillary tube 2, the light-weight patch 3 can be implanted to a greater depth, the imaging detection can be conveniently, accurately and clearly carried out.

Referring to a preparation flow chart shown in fig. 3, the lightweight ultrasonic easily developable patch disclosed by the invention is prepared by the following method:

firstly, selecting medical grade polypropylene monofilament with the diameter of 0.1mm, and weaving the medical grade polypropylene monofilament on a 16-20E and 2-3 bar Raschel warp knitting machine to prepare a mesh structure patch 3;

the mesh structure patch 3 which is well woven is lightly washed in cold water to remove surface impurities, and is naturally dried at normal temperature, so that the influence on the polypropylene caused by rearrangement of the molecular chain structure of the polypropylene due to high-temperature drying and the influence on the toughness of the finished product of the patch 3 are avoided.

After the patch 3 is woven, a medical-grade polypropylene capillary with the inner diameter of 1.5mm is selected as the developing capillary 2, and is processed to form a structure with a plurality of air bags 1.

At the temperature of about 200 ℃, the developing capillary 2 is subjected to segmented hot melting by using a plastic packaging part of a plastic packaging machine, namely, the developing capillary 2 moves along the direction vertical to the quick sealing opening, after the developing capillary 2 moves for a distance, the plastic packaging opening is pressed down to press the developing capillary 2, the developing capillary 2 at the pressed part is heated and melted, the upper end and the lower end of the inner wall of the developing capillary 2 are bonded to form a bonding part, the bonding part is naturally cooled at normal temperature, a plurality of discontinuous bonding parts are formed on the developing capillary 2, and thus a closed cavity structure can be formed between two adjacent bonding parts, and the airbag 1 for ultrasonic imaging can be enhanced.

The above-described bonded portion can be formed by a clamping device capable of applying pressure and temperature, such as a pair of pliers with temperature, which sequentially clamp the developing capillary 2 in the direction thereof, and the clamped portion is heated and melted.

After the developing capillary 2 is processed to be provided with a plurality of air bags 1, the developing capillary 2 is woven into a mesh-structured patch 3 to prepare a composite patch 3, and the composite patch 3 is subjected to heat setting in a mould, wherein the heat setting temperature is 120 ℃, and the setting time is 15-20min, so that the developing capillary 2 can be better attached to the mesh-structured patch 3.

After the heat setting is finished, the composite patch 3 is naturally cooled, so that the ultrasonic easily-developed light-weight patch can be cooled at a proper cooling speed, and the conditions of low crystallinity, low strength or too slow cooling speed, low crystallinity and poor toughness caused by too fast cooling are avoided.

The cooled composite patch 3 is cut into a required shape, and the air bags 1 on the developing capillary 2 ensure that most air bags 1 cannot be damaged due to cutting, so that the developing condition cannot be enhanced.

The ultrasound developable lightweight patch according to the present invention was implanted in a pig abdominal incision and subjected to a development test under the ABUS, as shown in figure 2, can obviously find that the white highlight image is the developing capillary 2, can obviously enhance the identification effect of the patch 3, in addition, the identification degree of the image at the two ends of the developing capillary 2 is obviously reduced, the reason is that the structure of the air bag 1 at both ends of the developing capillary 2 is damaged by cutting, and the closed air bag 1 cannot be formed, so that the discrimination is reduced, the multiple air bags 1 on the developing capillary 2 can prevent most of the air bags 1 from being affected by cutting, and the developing capillary 2 has a more obvious developing enhancing effect, so that the light-weight patch easy to develop by ultrasound disclosed by the invention can effectively solve the imaging detection difficulty of the light-weight patch 3 and the problem of low imaging resolution of ABUS at a deeper position.

Although the invention has been described herein with reference to a number of illustrative embodiments thereof, it should be understood that numerous other modifications and embodiments can be devised by those skilled in the art that will fall within the spirit and scope of the principles of this disclosure. More specifically, various variations and modifications are possible in the component parts and/or arrangements of the subject combination arrangement within the scope of the disclosure and claims of this application. In addition to variations and modifications in the component parts and/or arrangements, other uses will also be apparent to those skilled in the art.