阅读说明：本技术 一种自动进样器与洗针方法 (Automatic sample injector and needle washing method ) 是由 张习志 张恩来 卜秋祥 孙阳阳 于 2019-09-11 设计创作，主要内容包括：本发明公开了一种自动进样器,包括进样装置、样品盘,所述进样装置包括进样臂壳、进样臂、进样针和第一驱动装置,所述第一驱动装置设置于进样臂壳内,所述样品盘包括上盘体、下盘体,所述上盘体上设置有放置样品管或洗针管的管孔,所述管孔沿上盘体边缘一圈同心圆分布,所述下盘体上设置有对应管孔的定位圆槽,所述任一个管孔内固定放置一个抵接于对应的定位圆槽的洗针管,所述洗针管底端侧壁朝向样品盘中心的一侧设置有进液口,所述进液口通过连通管连接至清洗瓶底端侧壁的出液口,转盘底座内设有第二驱动装置。本发明还公开了一种自动进样器洗针方法。本发明实现了为洗针管自动加液的目的,提高了分析人员的工作效率,节省了人力。(The invention discloses an automatic sample injector which comprises a sample injection device and a sample disc, wherein the sample injection device comprises a sample injection arm shell, a sample injection arm, a sample injection needle and a first driving device, the first driving device is arranged in the sample injection arm shell, the sample disc comprises an upper disc body and a lower disc body, pipe holes for placing sample tubes or needle washing tubes are arranged on the upper disc body, the pipe holes are distributed along a circle of concentric circles on the edge of the upper disc body, positioning circular grooves corresponding to the pipe holes are arranged on the lower disc body, a needle washing tube abutting against the corresponding positioning circular groove is fixedly placed in any one pipe hole, a liquid inlet is formed in one side, facing the center of the sample disc, of the side wall at the bottom end of the needle washing tube, the liquid inlet is connected to a liquid outlet in the side wall at the bottom end of a cleaning bottle. The invention also discloses a needle washing method of the automatic sample injector. The automatic liquid feeding device realizes the purpose of automatically feeding liquid into the needle washing tube, improves the working efficiency of analysts and saves manpower.)

1. An automatic sample injector comprises a sample injection device (2) and a sample tray, wherein the sample injection device (2) is positioned on one side of the sample tray, the sample injection device (2) comprises a sample injection arm shell (201), a sample injection arm (203), a sample injection needle (206) and a first driving device, the first driving device is arranged in the sample injection arm shell (201) and is used for driving the sample injection arm (203) to move along the up-and-down direction, the sample injection needle (206) is matched and connected with the sample injection arm (203) through the first driving device, the automatic sample injector is characterized in that the sample tray comprises an upper tray body (101) and a lower tray body (102) which is connected with the upper tray body (101) through a supporting rod (104), the upper tray body (101) is a circular ring with a circular ring hole (111) in the middle, a tube hole (106) for placing a sample tube (105) or a needle washing tube (107) is arranged on the upper tray body (101), and the tube hole (106) is distributed, be provided with location circular slot (110) that correspond tube hole (106) on lower disk body (102), any tube hole (106) internal fixation places a butt in syringe (107) of washing of location circular slot (110) that corresponds, syringe (107) bottom lateral wall is provided with inlet (107a) towards one side at sample dish center, inlet (107a) are connected to liquid outlet (103b) of washing bottle (103) bottom lateral wall through communicating pipe (108), it sets firmly in lower disk body (102) central authorities to wash bottle (103) to pass ring hole (111), lower disk body (102) set firmly on carousel base (109), be equipped with the second drive arrangement that drive sample dish along the direction of the level or reverse rotation in carousel base (109).

2. The autosampler according to claim 1, wherein said lower tray (102) is provided with a rotating shaft (102a) connected to the second driving means in the middle, said rotating shaft (102a) protrudes upward from the surface of said lower tray (102), said cleaning bottle (103) is provided with a bottle bottom groove (103c) protruding inward in the center of the bottom, said bottle bottom groove (103c) is engaged with said rotating shaft (102 a).

3. The autosampler of claim 2, characterized in that said lower disc (102) is provided with an annular groove (102b) around the rotation axis (102a), said bottom groove (103c) extending outwards forming an annular boss (103d), said annular boss (103d) being snap-fitted into the annular groove (102 b).

4. The autosampler of claim 2, wherein said wash needle tube (107) has an inner diameter that decreases from top to bottom.

5. The autosampler according to claim 2, characterized in that, the first driving device comprises a screw (209), a guide post (208) symmetrically disposed parallel to the screw (209), a sliding block (212) and a first driving motor (210), the screw (209) is disposed vertically, one end of the screw (209) is connected to the first driving motor (210), the screw (209) and the guide post (208) are slidably connected to the sliding block (212), the first fixing seat (211) is disposed horizontally inside the sample arm housing (201), and the first driving motor (210) is fixed to the first fixing seat (211).

6. The autosampler according to claim 5, characterized in that a second fixing seat (213) is vertically arranged in the sample arm housing (201), one end of the second fixing seat (213) is vertically connected below the first fixing seat (211), and a slot (207) for allowing the edge of the lower tray (102) to pass through is arranged at the lower end of the second fixing seat (213).

7. The autosampler according to claim 6, characterized in that one end of the sampling arm (203) is connected to the slide block (212), the other end far away from the slide block (212) is provided with a first through hole (204a), one end of the sampling needle guide plate (205) is connected to the second fixing seat (213), and the other end is provided with a second through hole (205 a).

8. The autosampler according to claim 7, wherein the side of the arm housing (201) facing the sample plate is opened with an open slot (202), and the arm (203), the needle guide plate (205) and the slot (207) extend out of the arm housing (201) through the open slot (202).

9. The autosampler of claim 1, wherein said second drive means is a rack drive or a belt drive.

10. The method for needle washing of an autosampler according to claims 1-9, characterized in that it comprises the following steps:

step one, a second driving device drives a sample disc to drive a needle washing tube (107) to move to a position right below a sample injection needle (206), and a first driving device drives a sample injection arm (203) to move downwards so as to drive the sample injection needle (206) to be inserted downwards into the needle washing tube (107) to absorb liquid for needle washing;

step two, the liquid level in the syringe (107) is lowered, and the liquid in the cleaning bottle (103) is supplemented to the syringe (107) through the communicating pipe (108) under the action of atmospheric pressure;

and step three, repeating the steps until the liquid in the cleaning bottle (103) is used up.

Technical Field

The invention relates to the technical field of sample injection devices, in particular to an automatic sample injector and a needle washing method.

Background

Most modern analytical instruments adopt automatic sample injectors, which can reduce errors caused by manual operation and improve the measurement precision of samples; on the other hand, the measurement of multiple samples is automated, the analysis speed is improved, the working strength of analysts is reduced, and the working efficiency of the analysts is improved. An autosampler can be said to be one of the important components of modern analytical instruments. The automatic sample injector is an important functional device of an analysis instrument and provides a front-end sample loading function for instrument analysis, but the mechanical structures of the automatic sample injector are various, and for the sample injector with a simple structure, because the used driving part is simple, the moving range of a mechanical part is limited, and some functions cannot be realized. For example, in a general situation, an automatic sample injector is applied to operate on the basis of a preset program, so that a single timing, quantitative and fixed-point sample injection function is realized, and for a common needle washing function, one method is realized by alternately placing needle washing tubes and sample tubes on a sample disc; the other method is to place only one needle washing tube on the sample disc, but the volume of the needle washing tube is very small, the needle washing liquid can not be automatically added in the sample introduction process, and a large amount of manual liquid adding work is also needed. Therefore, in the prior art, the needle washing and liquid adding of the automatic sample injector are complicated, and the working efficiency is low.

Disclosure of Invention

The technical problem to be solved by the invention is as follows: the automatic sample injector and the needle washing method solve the problem that the needle washing and liquid adding of the automatic sample injector in the prior art are complicated, so that the working efficiency is low, realize the function of needle washing and liquid adding of the automatic sample injector, improve the working efficiency of analysts and save manpower.

In order to solve the technical problems, the invention adopts the following technical scheme:

an automatic sample injector comprises a sample injection device and a sample disc, wherein the sample injection device is positioned on one side of the sample disc, the sample injection device comprises a sample injection arm shell, a sample injection arm, a sample injection needle and a first driving device, the first driving device is arranged in the sample injection arm shell and used for driving the sample injection arm to move along the up-down direction, the sample injection needle is matched and connected with the sample injection arm through the first driving device, the sample disc comprises an upper disc body and a lower disc body which is connected with the upper disc body through a supporting rod, the upper disc body is in a ring shape with a ring hole in the middle, a tube hole for placing a sample tube is arranged on the upper disc body, the tube hole is distributed along a circle of concentric circles on the edge of the upper disc body, a positioning circular groove corresponding to the tube hole is arranged on the lower disc body, a needle tube which is abutted to the corresponding positioning circular groove is fixedly placed in any tube hole, and, the inlet is connected to the liquid outlet of wash-bottle bottom lateral wall through communicating pipe, the wash-bottle passes the ring hole and sets firmly in lower disk body central authorities, the lower disk body sets firmly on the carousel base, be equipped with the second drive arrangement that drives sample dish along the forward or reverse rotation of horizontal direction in the carousel base.

The automatic sample injector provided by the invention adopts the principle of a communicating vessel, under the conditions that the original structure is not changed and a driving part is not added, when a needle needs to be washed, liquid in a washing bottle flows into a needle washing tube along a communicating tube under the action of atmospheric pressure, after the liquid in the needle washing tube is sucked away by a sample injection needle, the liquid level in a sample tube descends, and the liquid in the washing bottle is supplemented to the needle washing tube under the action of atmospheric pressure, and the steps are repeated until the solution in the washing bottle is used up; in addition, the second driving device can drive the sample disc to rotate forward or backward, so that the needle washing tube or the sample tube rotates to the position below the sample injection needle, and then the first driving device drives the sample injection needle to move up and down, so that the sample injection needle is inserted into the corresponding needle washing tube to wash the needle or is inserted into the corresponding sample tube to absorb a sample.

According to the automatic sample injector, the rotating shaft connected with the second driving device is arranged in the middle of the lower tray body, the rotating shaft protrudes upwards out of the surface of the lower tray body, the center of the bottom of the cleaning bottle is provided with a bottle bottom groove protruding inwards, and the bottle bottom groove is clamped on the rotating shaft.

As above automatic sample injector, the lower disk is fitted with a contraceptive ring and is provided with the annular groove around the axis of rotation, the outside extension of bottle bottom recess forms annular boss, annular boss joint is in the annular groove.

According to the automatic sample injector, the inner diameter of the needle washing tube is reduced from top to bottom in sequence.

As above autosampler, first drive arrangement includes lead screw, the guide post that is on a parallel with the lead screw symmetry and sets up, slider and first driving motor, the vertical setting of lead screw, the one end and the first driving motor of lead screw are connected, lead screw and guide post respectively with slider sliding connection, first fixing base level set up in advance in the appearance arm shell, first driving motor sets firmly on first fixing base.

The automatic sample injector is characterized in that a second fixing seat is vertically arranged in the sample injection arm shell, one end of the second fixing seat is vertically connected to the first fixing seat, and a clamping groove which is used for accommodating the edge of the lower tray body and penetrates when the edge of the lower tray body rotates is formed in the lower end of the second fixing seat.

According to the automatic sample injector, one end of the sample injection arm is connected to the sliding block, the other end, far away from the sliding block, of the sample injection arm is provided with the first through hole, one end of the sample injection needle guide plate is connected to the second fixing seat, and the other end of the sample injection needle guide plate is provided with the second through hole.

According to the automatic sample injector, an open slot is formed in one side, facing the sample disc, of the sample injection arm shell, and the sample injection arm, the sample injection needle guide plate and the clamping slot extend out of the sample injection arm shell through the open slot.

In the automatic sample injector, the second driving device is a rack gear or a belt gear.

In another aspect of the present invention, there is provided a needle washing method of an autosampler, comprising the steps of:

the method comprises the following steps that firstly, a second driving device drives a sample disc to drive a needle washing tube to move to a position right below a sample injection needle, and a first driving device drives a sample injection arm to move downwards so as to drive the sample injection needle to be inserted downwards into the needle washing tube to absorb liquid to wash the needle;

step two, the liquid level in the needle washing tube is lowered, and the liquid in the cleaning bottle is supplemented to the needle washing tube through the communicating tube under the action of atmospheric pressure;

and step three, repeating the steps until the liquid in the cleaning bottle is used up.

The invention has the following advantages and beneficial effects:

1. by adopting the design of the invention, under the condition of not influencing the positioning accuracy, as only one needle washing tube is provided, more sample tubes can be placed in a certain space, and the working efficiency of measuring the sample to be measured is greatly improved.

2. The automatic sample injector provided by the invention is matched with the existing analytical instrument, the automatic liquid adding function of the needle washing tube is realized under the conditions of not changing the original structure and not increasing a driving part, the resources are saved, the processing is convenient, and the cost is low.

Drawings

In order to more clearly illustrate the technical solutions of the present invention or the prior art, the following will briefly describe the drawings needed for the embodiments or the prior art descriptions, and it is obvious that the following description is only one embodiment of the present invention, and those skilled in the art can also obtain other drawings according to the drawings without creative efforts.

FIG. 1 is a schematic diagram of an autosampler configuration according to the present invention;

FIG. 2 is a schematic side view of an autosampler according to the present invention;

FIG. 3 is a cross-sectional view of the cleaning bottle and the cleaning needle tube respectively connected to the communicating tube;

FIG. 4 is a cross-sectional view of the cleaning bottle;

FIG. 5 is a cross-sectional view of the needle wash tube;

FIG. 6 is a side view of the internal structure of the sample injection device;

FIG. 7 is a front view of the internal structure of the sample injection device;

FIG. 8 is a sectional view of the internal structure of the sample injection device.

101-upper tray body, 102-lower tray body, 102 a-rotating shaft, 102 b-annular groove, 103-cleaning bottle, 103 a-bottle cap, 103 b-liquid outlet, 103 c-bottle bottom groove, 103 d-annular boss, 104-supporting rod, 105-sample tube, 106-tube hole, 107-syringe tube, 107 a-liquid inlet, 108-communicating tube, 109-turntable base, 110-positioning circular groove, 111-circular hole, 2-sample injection device, 201-sample injection arm shell, 202-open slot, 203-sample injection arm, 204-sample injection needle fixed block, 204 a-first through hole, 205-sample injection needle guide plate, 205 a-second through hole, 206-sample injection needle, 207-neck, 208-guide column, 209-lead screw, 210-a first driving motor, 211-a first fixed seat, 212-a sliding block, 213-a second fixed seat, 214-a first optical coupling baffle, 3-a sample feeding base, 301-a touch screen, 302-a six-way valve and 303-a peristaltic pump.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments of the present invention, belong to the protection scope of the present invention.

In the present invention, unless otherwise expressly specified or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.