阅读说明：本技术 热稳定的液体轮状病毒疫苗 (Thermostable liquid rotavirus vaccine ) 是由 S.V.卡普雷 I.A.奥拉夫 于 2018-02-14 设计创作，主要内容包括：本发明涉及一种由在非水性液体中的微粉化冻干轮状病毒颗粒乳剂和缓冲赋形剂组成的口服疫苗。这种IVT-06制剂通过在30℃和40℃的温度下保护病毒至少12个月而赋予热稳定性。从12个月的稳定性数据推断,表明保存期在30℃下超过2年,且在50℃下6个月。此外,为易于施用,配制的剂量的体积为0.5 Ml。(The present invention relates to an oral vaccine consisting of an emulsion of micronized lyophilized rotavirus particles in a non-aqueous liquid and a buffering excipient. This IVT-06 formulation confers thermal stability by protecting the virus at temperatures of 30 ℃ and 40 ℃ for at least 12 months. Inferred from the 12 month stability data, the shelf life was shown to be over 2 years at 30 ℃ and 6 months at 50 ℃. Furthermore, for ease of administration, the volume of the dose formulated is 0.5 Ml.)