阅读说明：本技术 快速治疗慢性湿疹的药水及其制备方法 (Liquid medicine for quickly treating chronic eczema and preparation method thereof ) 是由 陈晓楠 陈晓军 张维霞 杜乃云 于 2019-09-30 设计创作，主要内容包括：本发明公开了一种快速治疗慢性湿疹的药水,包括以下重量配比的组分,地塞米松0.35～0.65g、冰片10～20g、水杨酸5～50g、醋酸双氯苯双胍己烷0.5～6g、维生素B<Sub>1</Sub> 5～20g、甘油45～55毫升、95％的乙醇790毫升,蒸馏水适量加到1000毫升混匀即可；还公开了该药物的具体制备方法,使用方法是药水涂抹在皮肤表面湿疹的地方,一分钟左右即可见效,如有分泌物渗出,搽药后约十分钟左右,湿疹处干燥不再有分泌物渗出,适合各年龄段人群使用,治疗效果好,治愈后复发率低,治疗周期短,费用低。(The invention discloses a liquid medicine for quickly treating chronic eczema, which comprises, by weight, 0.35-0.65 g of dexamethasone, 10-20 g of borneol, 5-50 g of salicylic acid, 0.5-6 g of chlorhexidine acetate, and vitamin B 1 5-20 g of glycerinAdding 45-55 ml of 95% ethanol 790 ml and a proper amount of distilled water to 1000ml of the mixture, and uniformly mixing; the medicine is applied to the eczema part on the skin surface, the effect can be achieved within about one minute, if secretion exudes, the medicine is applied for about ten minutes, the eczema part is dry and does not exude any more, the medicine is suitable for people of all ages, the treatment effect is good, the recurrence rate after healing is low, the treatment period is short, and the cost is low.)

1. The liquid medicine for quickly treating chronic eczema is characterized by comprising 1000ml of liquid medicine prepared from the following components in parts by weight:

0.35-0.65 g of dexamethasone, 10-20 g of borneol, 5-50 g of salicylic acid, 0.5-6 g of chlorhexidine acetate and vitamin B₁5-20 g, 45-55 ml of glycerol, 790 ml of 95% ethanol and a proper amount of distilled water added to 1000 ml.

2. The liquid medicine for rapidly treating chronic eczema as claimed in claim 1, wherein the liquid medicine comprises 1000ml of liquid medicine prepared from the following components in parts by weight:

dexamethasone 0.5g, borneol 20g, salicylic acid 20g, chlorhexidine acetate 3g, vitamin B₁20g, 50 ml of glycerol, 790 ml of 95% ethanol and a proper amount of distilled water added to 1000 ml.

3. The method for preparing the lotion for rapidly treating chronic eczema as claimed in claim 1 or 2, comprising the steps of:

step one, taking 0.5g of dexamethasone, putting the dexamethasone into a 100 ml measuring cup, and adding 50 ml of distilled water at 60 ℃ for dissolving for later use;

step two, dissolving 20g of salicylic acid into 790 ml of 95% ethanol, stirring for dissolving, then adding 20g of borneol, and stirring for dissolving for later use;

step three, 3g of chlorhexidine acetate is added into 50 ml of distilled water with the temperature of 60 ℃ for dissolution, and then 20g of vitamin B is added₁Dissolving for later use;

step four, sequentially adding the solutions prepared in the steps into a 1000ml measuring cup, uniformly stirring, adding 50 ml of glycerol, uniformly mixing, adding a proper amount of distilled water, uniformly mixing to prepare 1000ml of solution, and uniformly mixing;

and step five, subpackaging the liquid medicine prepared in the step four into 50 ml bottles, and storing the bottles in dark at normal temperature.

Technical Field

The invention relates to the technical field of eczema treatment, in particular to a liquid medicine for quickly treating chronic eczema and a specific preparation method of the liquid medicine.

Background

Eczema is one of the most common diseases in dermatology, and various types of eczema can account for 20% of outpatients of dermatology. Eczema is a complex etiology, often resulting from the interaction of internal and external factors. Internal factors such as chronic digestive system diseases, mental stress, insomnia, overfatigue, mood changes, endocrine dyscrasia, infection, metabolism disorder and the like, and external factors such as living environment, climate changes, food and the like can influence the occurrence of eczema. External stimuli such as sunlight, cold, dryness, heat, hot water scald, and various animal skins, plants, cosmetics, soaps, artificial fibers, etc. can induce, in short, a delayed type allergic reaction caused by complicated internal and external factors. Most of the existing medicines for treating eczema take antiallergic medicines and hormone therapy, and have the advantages of slow effect, poor effect and high recurrence rate.

Disclosure of Invention

The invention aims to solve the problem of quickly treating chronic eczema by taking effect quickly, externally applying medicine, having small side effect and high cure rate.

In order to solve the technical problems, the technical scheme of the invention is as follows: the liquid medicine for quickly treating chronic eczema comprises 1000ml of liquid medicine prepared from the following components in parts by weight:

0.35-0.65 g of dexamethasone, 10-20 g of borneol, 5-50 g of salicylic acid, 0.5-6 g of chlorhexidine acetate and vitamin B₁5-20 g, 45-55 ml of glycerol, 790 ml of 95% ethanol and a proper amount of distilled water added to 1000 ml.

As an improvement to the technical scheme, the lotion comprises 1000ml of lotion prepared from the following components in parts by weight:

dexamethasone 0.5g, borneol 20g, salicylic acid 20g, chlorhexidine acetate 3g, vitamin B₁20g, 50 ml of glycerol, 790 ml of 95% ethanol and a proper amount of distilled water added to 1000 ml.

As an improvement to the above technical scheme, the method comprises the following steps:

step one, taking 0.5g of dexamethasone, putting the dexamethasone into a 100 ml measuring cup, and adding 50 ml of distilled water at 60 ℃ for dissolving for later use;

step two, dissolving 20g of salicylic acid into 790 ml of 95% ethanol, stirring for dissolving, then adding 20g of borneol, and stirring for dissolving for later use;

step three, 3g of chlorhexidine acetate is added into 50 ml of distilled water with the temperature of 60 ℃ for dissolution, and then 20g of vitamin B is added₁Dissolving for later use;

step four, sequentially adding the solutions prepared in the steps into a 1000ml measuring cup, uniformly stirring, adding 50 ml of glycerol, uniformly mixing, adding a proper amount of distilled water, uniformly mixing to prepare 1000ml of solution, and uniformly mixing;

and step five, subpackaging the liquid medicine prepared in the step four into 50 ml bottles, and storing the bottles in dark at normal temperature.

Due to the adoption of the technical scheme, the invention has the following technical effects: the liquid medicine is smeared on the part where eczema grows on the surface of the skin, itching relieving speed is high, the liquid medicine can take effect within about one minute, a patient with serious eczema and secretion exudation has about ten minutes, the eczema is dry, secretion exosmosis is avoided, the recurrence rate after healing is low, the liquid medicine is suitable for people of all ages, the universality is strong, the treatment period is short, the treatment cost is low, and the problems that most of chronic eczema is difficult to treat, needs to be maintained by hormone and anti-allergic medicines and recurs are solved.

Detailed Description

The invention is further illustrated by the following examples. In the following detailed description, certain exemplary embodiments of the present invention are described by way of illustration only. Needless to say, a person skilled in the art realizes that the described embodiments can be modified in various different ways without departing from the spirit and scope of the present invention. Accordingly, the description is illustrative in nature and not intended to limit the scope of the claims.

Liquid medicine for quickly treating chronic eczema comprising the following components1000ml of liquid medicine prepared from the components according to the weight ratio, 0.35-0.65 g of dexamethasone, 10-20 g of borneol, 5-50 g of salicylic acid, 0.5-6 g of chlorhexidine acetate, and vitamin B₁5-20 g, 45-55 ml of glycerol, 790 ml of 95% ethanol and a proper amount of distilled water added to 1000 ml.

The medicine comprises the following components, by weight, 0.5g of dexamethasone, 20g of borneol, 20g of salicylic acid, 3g of chlorhexidine acetate and vitamin B₁20g, 50 ml of glycerol and 790 ml of 95 percent ethanol, and when the components in the weight ratio are mixed and then added with distilled water to form 1000ml of liquid medicine, the treatment effect is good.

The invention also relates to a specific preparation method of the liquid medicine for quickly treating chronic eczema, which comprises the following steps:

step one, 0.5g of dexamethasone is taken and put into a 100 ml measuring cup, and 50 ml of distilled water with the temperature of 60 ℃ is added for dissolving for standby. Dexamethasone has strong antiinflammatory effect, can contract blood vessel of inflammation part, reduce capillary permeability, reduce exudation, congestion, edema and cell infiltration of inflammation, relieve red swelling and pain of skin, and has antiinflammatory, antiviral and antiallergic effects.

And step two, dissolving 20g of salicylic acid into 790 ml of 95% ethanol, stirring for dissolving, then adding 20g of borneol, and stirring for dissolving for later use. Salicylic acid has effects of dissolving skin cutin and killing fungi, and Borneolum has effects of relieving pain and resisting bacteria.

Step three, 3g of chlorhexidine acetate is added into 50 ml of distilled water with the temperature of 60 ℃ for dissolution, and then 20g of vitamin B is added₁Dissolving for later use. The chlorhexidine acetate is a broad-spectrum bactericide, can kill bacteria, fungi and viruses on the surface of the skin, has strong penetrating power even in the presence of blood stains, and has an effective treatment effect on skin bacterial and viral infection. Vitamin B₁Can effectively treat skin edema and peripheral nerve inflammation, and the combination of the two can effectively improve the treatment effect.

And step four, sequentially adding the solutions prepared in the steps into a 1000ml measuring cup, uniformly stirring, adding 50 ml of glycerol, uniformly mixing, adding a proper amount of distilled water, uniformly mixing to prepare 1000ml of solution, and uniformly mixing. The glycerin plays a role of a suspending agent in the medicine, belongs to a high molecular hydrophilic colloid substance, and has the functions of preventing or reducing the attraction or flocculation among particles and maintaining the uniform dispersion state of the particles, thereby ensuring the uniform distribution of effective molecules in the liquid medicine and having the lubrication effect on the skin.

And step five, subpackaging the liquid medicine prepared in the step four into 50 ml per bottle, and storing the liquid medicine at the normal temperature in a dark place to ensure the quality of the liquid medicine after the liquid medicine is prepared and subpackaged.

The using method comprises the following steps: the medicine is applied for 1-2 times every day.

The use effect is as follows: common infantile and children eczema and chronic eczema, serious patients have pruritus of different degrees and even secretion exudation, after the liquid medicine is applied, itching can be relieved within about one minute, the serious patients can be cured within 3-10 days generally, the possible cure time of the serious patients is prolonged, and more than 60 percent of patients can be cured basically. When used by adults, the medicine can be taken orally and used together with other medicines, and infants do not need to be matched with the oral medicines.

Contraindications or precautions: through trial, no side effect is found at present, but the traditional Chinese medicine composition is used with caution by people with allergic constitution and is strictly taken orally.

Specific case 1:

five-year-old boys suffer from eczema in 80% of the whole body, and local secretion is seriously exuded, so that the five-year-old boys are extremely painful. The treatment is carried out in a hospital for about four months, the patient is hospitalized for more than ten days in the initial treatment period, oral medicines are matched in the treatment period, the dosage of the medicines is large, and the hormone medicines have large specific gravity, so that the face is fat and the skin color is pale, and the eczema is faded after the treatment, but gradually relapsed after the medicine is stopped for about twenty days, so that the treatment of the eczema after the patient is hospitalized is not radical. The recurrence of the eczema on the whole body of the boy is serious, the exudation part of the secretion is dry after the medicine of the embodiment is used for about ten minutes, the part with red lesion is obviously lightened, and the skin is recovered to be normal after half a month of the medicine application.

Specific case 2:

the ten-month-old infant has eczema with different degrees at forehead, cheek, mouth corner and lower jaw, local secretion exudation, facial obesity caused by hormone administration due to the age of the patient, dark background color and early scar after the medicine control of serious parts. After the medicine of the embodiment is used for about ten minutes, the exudation of the secretion exudation part stops, and the skin of the eczema part is healed without scar formation on the 20 th day of the medicine application.

Specific case 3:

twelve-year-old girls suffer from eczema in the whole body, are different in degree and intensity, have secretion exudation in the local part, are extremely itchy and unbearable, and seriously affect sleeping and learning. After ten minutes of the initial administration, the secretion of the eczema part disappears, and the itching is immediately relieved, the eczema is completely eliminated after about one month of the administration, and no relapse sign is observed in the period.

Synthesize above-mentioned clinical trial situation, select 50 1 ~ 15 year of the volunteer subjects, two sets of subjects age and eczema severity are the same, and a set uses the treatment medicine that this embodiment was prepared according to the advice, and another group uses the conventional treatment medicine on the existing market to treat according to the advice, and in the same treatment time, compare two sets of treatment effect before and after using, specifically as shown in Table 1.

Somewhat effective: no secretion continues to exude from the eczema part, the itching feeling is obviously relieved, and the influence on sleep or learning is basically avoided.

Obviously effective: the skin of the eczema part is healed without scar formation, and no relapse signs are continuously observed.

Basically, ineffective: the eczema part is not obviously improved, the itching relieving effect is obvious after each time of medicine application, and the itching relieving effect is obviously weakened after the medicine effect is over.

When the liquid medicine is used, the liquid medicine is smeared on the part where eczema grows on the surface of the skin, the itching relieving speed is high, the liquid medicine can take effect within about one minute, the serious eczema has secretion exudation for about ten minutes, the eczema is dry, the secretion extravasation is not caused, the recurrence rate after curing is low, the liquid medicine is suitable for people of all ages, the universality is strong, the treatment period is short, the treatment cost is low, and the problems that most of chronic eczema is difficult to treat, needs to be maintained by hormone and antiallergic medicines and is recurrent are solved.

The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.