表皮生长因子在治疗糖尿病性足溃疡中的用途

文档序号:1909092 发布日期:2021-11-30 浏览:4次 >En<

阅读说明:本技术 表皮生长因子在治疗糖尿病性足溃疡中的用途 (Use of epidermal growth factor in the treatment of diabetic foot ulcers ) 是由 A·德里奥马丁 J·E·萨屋里察维兹 R·乌比塔戈麦斯 S·冈萨雷斯巴兰寇 J·A·贝尔兰嘉 于 2020-03-16 设计创作,主要内容包括:本发明涉及表皮生长因子(EGF)在制备可注射药物中的用途,所述可注射药物用于在评价之时不具备患病肢截肢标准的患者中治疗糖尿病性足溃疡(DFU),其中每周一次通过损伤内浸润到所述溃疡中来施用所述包含EGF的药物。此外,本发明提供了用于在患者中治疗DFU的包含EGF的药用组合物,其中每周一次施用所述组合物。本发明还考虑了用于在评价之时不具备患病肢截肢标准的患者中治疗DFU的方法,其包括每周一次通过损伤内浸润到所述溃疡的床体中来向所述患者施用EGF。(The present invention relates to the use of Epidermal Growth Factor (EGF) in the preparation of an injectable medicament for the treatment of Diabetic Foot Ulcers (DFU) in patients not having criteria for affected limb amputation at the time of evaluation, wherein said medicament comprising EGF is administered once a week by intralesional infiltration into said ulcers. Further, the present invention provides a pharmaceutical composition comprising EGF for use in treating DFU in a patient, wherein the composition is administered once weekly. The invention also contemplates a method for treating DFU in a patient who does not have the criteria for diseased limb amputation at the time of evaluation, comprising administering EGF once per week to said patient by intralesional infiltration into the bed of said ulcer.)

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