阅读说明：本技术 制备6-(1-丙烯酰基哌啶-4-基)-2-(4-苯氧基苯基)尼克酰胺的工艺 (Process for the preparation of 6- (1-acryloylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide ) 是由 陈向阳 于 2020-02-24 设计创作，主要内容包括：本发明涉及大于1公斤的大量制备6-(1-丙烯酰基哌啶-4-基)-2-(4-苯氧基苯基)尼克酰胺(化合物I)的工艺。该工艺提供了良好的产率和至少95％纯度的最终产物,并提供可控且安全的反应。(The invention relates to a process for the preparation of 6- (1-acryloylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide (compound I) in large quantities of more than 1 kg. The process provides good yields and final products of at least 95% purity, and provides a controlled and safe reaction.)